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Journal Articles

Arterio-occlusive events among patients with chronic myeloid leukemia on tyrosine kinase inhibitors

Lukas Veltmaat, Jorge Cortes
Journal: Blood
Blood (2024) 143 (10): 858–865.
https://doi.org/10.1182/blood.2023022403
Published: 2024
Journal Articles

Patient-Reported Outcomes in Acute Myeloid Leukemia Patients with FLT3 -ITD Mutation Receiving Quizartinib Vs. Standard Chemotherapy: Results from the Quantum-First Trial

Esther Natalie Oliva, Sudhir Unni, Francesco Cottone, Rohan Vashi, Xiaocong Li, Jorge Cortes, Mikkael A. Sekeres
Journal: Blood
Blood (2023) 142 (Supplement 1): 918.
https://doi.org/10.1182/blood-2023-189035
Published: 2023
Journal Articles

Hidac Consolidation Cycles May Impede Stem Cell Transplant Planning for High-Risk Acute Myeloid Leukemia Patients

Michael Stokes, Danielle Bradshaw, Yazmin Reategui, Isabela Pavkov, Mohammad Mian, Locke Johnson Bryan, Amany R. Keruakous, Ayushi Chauhan, Jorge Cortes, Anand Jillella, Vamsi K. Kota
Journal: Blood
Blood (2023) 142 (Supplement 1): 5854.
https://doi.org/10.1182/blood-2023-191220
Published: 2023
Journal Articles

Asciminib (ASC) in Combination with Imatinib (IMA), Nilotinib (NIL), or Dasatinib (DAS) May be a Potential Treatment (Tx) Option in Patients (Pts) with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase or Accelerated Phase (Ph+ CML-CP/AP): Final Results from the Asciminib Phase 1 Study

Jorge Cortes, Fabian Lang, Delphine Rea, Andreas Hochhaus, Massimo Breccia, Yeow Tee Goh, Michael C. Heinrich, Timothy P Hughes, Jeroen J.W.M. Janssen, Philipp le Coutre, Hironobu Minami, Koji Sasaki, Daniel J. DeAngelo, Gessami Sanchez-Olle, Nathalie Pognan, Jomy Jose, Matthias Hoch, Michael Mauro
Journal: Blood
Blood (2023) 142 (Supplement 1): 868.
https://doi.org/10.1182/blood-2023-189270
Published: 2023
Journal Articles

Long-Term Results from the Optic Trial: A Dose-Optimization Study of 3 Starting Doses of Ponatinib

Jorge Cortes, Michael Deininger, Elza Lomaia, Beatriz Moiraghi, Soledad Undurraga, Carolina Pavlovsky, Charles Chuah, Tomasz Sacha, Jeffrey H. Lipton, James McCloskey, Andreas Hochhaus, Philippe Rousselot, Gianantonio Rosti, Hugues de Lavallade, Anna Turkina, Lori Maness, Moshe Talpaz, Michael Mauro, Vickie Lu, Alexander Vorog, Jane F Apperley
Journal: Blood
Blood (2023) 142 (Supplement 1): 3164.
https://doi.org/10.1182/blood-2023-178790
Published: 2023
Journal Articles

The Overuse of C. Difficile T esting Among Autologous Transplant Patients with Melphalan Conditioning: A Single Center Experience

James Dickey, Meaghan Standridge, Shreya Desai, Isabela Pavkov, Stacy Bedore, Priyanshu Nain, Mohammad Mian, Ayushi Chauhan, Amany R. Keruakous, Locke Johnson Bryan, Anand Jillella, Jorge Cortes, Vamsi K. Kota
Journal: Blood
Blood (2023) 142 (Supplement 1): 7065.
https://doi.org/10.1182/blood-2023-191226
Published: 2023
Journal Articles

Update of Olverembatinib (HQP1351) Overcoming Ponatinib and/or Asciminib Resistance in Patients (Pts) with Heavily Pretreated/Refractory Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph + ALL)

Elias Jabbour, Hagop M. Kantarjian, Paul B. Koller, Omer Jamy, Vivian G. Oehler, Elza Lomaia, Anthony M. Hunter, Olga Uspenskaya, Svetlana Samarina, Sudipto Mukherjee, Maria R. Baer, Vera Zherebtsova, Vasily Shuvaev, Anna Turkina, Igor Davydkin, Jorge Cortes, Huanshan Guo, Zi Chen, Lei Fu, Hengbang Wang, Lixin Jiang, Cunlin Wang, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1798.
https://doi.org/10.1182/blood-2023-187744
Published: 2023
Journal Articles

Does Detection of <20% Lymphoblasts in Patients with CML Herald Imminent Blast Crisis? a Study from BCR::ABL1 Pathology Group

Zimu Gong, Lianqun Qiu, Joseph DiGiuseppe, Mengxing Xue, Lorinda Soma, Wei Wang, Yi Zhou, Qi Shen, Mingqing Zhu, Anisha Naik, Weina Chen, Wei J Wang, Sa A. Wang, L. Jeffrey Medeiros, Elias Jabbour, Hagop M. Kantarjian, Jorge Cortes, Jerald P. Radich, Joseph D. Khoury, Andreas Hochhaus, Jane F Apperley, Suning Chen, Kikkeri N Naresh, Shimin Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2023-187020
Published: 2023
Journal Articles

Improving Clinical Outcomes in APL: Weight Maintenance Strategies to Reduce Complications during Induction Therapy

Shreya Desai, Anvay Shah, Michael Stokes, Danielle Bradshaw, Mohammad Mian, Ayushi Chauhan, Amany R. Keruakous, Locke Johnson Bryan, Jorge Cortes, Vamsi K. Kota, Anand Jillella
Journal: Blood
Blood (2023) 142 (Supplement 1): 5873.
https://doi.org/10.1182/blood-2023-190745
Published: 2023
Journal Articles

Serum Ferritin Levels Prior to Mobilization and Collection May Not Influence Stem Cell Yield

Charles Weeks, Danielle Bradshaw, Sujith Abbagoni, Mohammad Mian, Sarah Jimenez, Courtney Corley, Amany R. Keruakous, Ayushi Chauhan, Locke Johnson Bryan, Jorge Cortes, Anand Jillella, Vamsi K. Kota
Journal: Blood
Blood (2023) 142 (Supplement 1): 4894.
https://doi.org/10.1182/blood-2023-191204
Published: 2023
Journal Articles

HJKC3-0006: Outcome of Patients with CML Treated on Second Line or Later Therapy in Routine Clinical Practice

James E Thompson, Yan Gao, Alexis Visotcky, Kathryn E Flynn, Michael Mauro, Emily Giever, Arielle Baim, Idayat Akinola, Richard Larson, Omer Jamy, Anthony M. Hunter, Vamsi K. Kota, Jorge Cortes, Brian J. Druker, Neil P. Shah, Javier Pinilla-Ibarz, Jay Yang, Ellen K. Ritchie, Lindsay A.M Rein, B. Douglas Smith, Srinivas K. Tantravahi, Talha Badar, Michael W. Deininger, Ehab L. Atallah
Journal: Blood
Blood (2023) 142 (Supplement 1): 7420.
https://doi.org/10.1182/blood-2023-179963
Published: 2023
Journal Articles

ASC2ESCALATE: A US Phase 2, Open-Label, Single-Arm, Dose-Escalation Study of Asciminib (ASC) Monotherapy in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) As Second-Line (2L) and First-Line (1L) Treatment

Ehab L. Atallah, Michael Mauro, Koji Sasaki, Moshe Levy, Paul B. Koller, Daisy Yang, Dramane Laine, John Sabo, Ennan GU, Jorge Cortes
Journal: Blood
Blood (2023) 142 (Supplement 1): 6389.
https://doi.org/10.1182/blood-2023-186974
Published: 2023
Journal Articles

ASC4START and ASC4FIRST: Two Ongoing Phase 3 Trials Investigating Asciminib Monotherapy As First-Line Therapy Versus Tyrosine Kinase Inhibitors in Patients with Newly Diagnosed Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase

Andreas Hochhaus, Jorge Cortes, Naoto Takahashi, Richard A. Larson, Ghayas C. Issa, Felice Bombaci, Susanne Saussele, Francois Mahon, Tim H. Brümmendorf, Shruti Kapoor, Tracey McCulloch, Peter Schuld, Timothy P Hughes
Journal: Blood
Blood (2023) 142 (Supplement 1): 6388.
https://doi.org/10.1182/blood-2023-186773
Published: 2023
Journal Articles

Financial Trends of AML Patients over the Past Decade

Mark Dalgetty, Mahran Shoukier, Danielle Bradshaw, Faizan Boghani, Sruthi Athota, Anvay Shah, Meaghan Standridge, Michael Stokes, Mohammad Mian, Ayushi Chauhan, Amany R. Keruakous, Locke Johnson Bryan, Jorge Cortes, Anand Jillella, Vamsi K. Kota
Journal: Blood
Blood (2023) 142 (Supplement 1): 5876.
https://doi.org/10.1182/blood-2023-191103
Published: 2023
Journal Articles

Drug Development for Leukemia : Comprehensive Analysis of Clinical Trial Success Rates Presented at the American Society Hematology (ASH) Annual Meetings

Kellen Tjioe, Marisol Miranda-Galvis, Thalyta Medeiros, Kenza Mamouni, Brenda Santellano, Claudia Guillen, Jorge Cortes
Journal: Blood
Blood (2023) 142 (Supplement 1): 3802.
https://doi.org/10.1182/blood-2023-182247
Published: 2023
Journal Articles

With up to 8 Years of Therapy, Asciminib (ASC) Monotherapy Demonstrated Continued Favorable Efficacy, Safety, and Tolerability in Patients (Pts) with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase (Ph+ CML-CP) without the T315I Mutation: Final Results from the Phase 1 X2101 Study

Andreas Hochhaus, Dong-Wook Kim, Jorge Cortes, Koji Sasaki, Michael Mauro, Timothy P Hughes, Massimo Breccia, Moshe Talpaz, Hironobu Minami, Yeow Tee Goh, Daniel J. DeAngelo, Fabian Lang, Michael C. Heinrich, Valle Gomez G De Soria, Philipp le Coutre, Gessami Sanchez-Olle, Jomy Jose, Nathalie Pognan, Shruti Kapoor, Delphine Rea
Journal: Blood
Blood (2023) 142 (Supplement 1): 450.
https://doi.org/10.1182/blood-2023-187322
Published: 2023
Journal Articles

Disparities in Phase 3 Leukemia Trials from the Last Decade: A Long Way to Go

Andres Noyola-Perez, Alejandra J. Osuna-Corrales, Manali I. Patel, Jorge Cortes, Lillian Sung, Juan C. Angulo-Lozano, Perla R. Colunga-Pedraza, David Gomez-Almaguer, Guillermo José Ruiz-Arguelles, Andres Gomez-De Leon
Journal: Blood
Blood (2023) 142 (Supplement 1): 494.
https://doi.org/10.1182/blood-2023-189576
Published: 2023
Journal Articles

Olutasidenib for the Treatment of mIDH1 Acute Myeloid Leukemia in Patients Relapsed or Refractory to Hematopoietic Stem Cell Transplant, Prior mIDH1 Inhibitor, or Venetoclax

Jorge Cortes, Joseph Jurcic, Maria R. Baer, William Blum, P. Brent Ferrell, Jr., Brian A. Jonas, Sangmin Lee, Alice Mims, Shyam Ajay Patel, Gary J. Schiller, Jay Yang, Justin M. Watts
Journal: Blood
Blood (2023) 142 (Supplement 1): 2888.
https://doi.org/10.1182/blood-2023-187861
Published: 2023
Journal Articles

Quantum-First Trial: FMS-like Tyrosine Kinase 3-Internal Tandem Duplication ( FLT3 -ITD)-Specific Measurable Residual Disease (MRD) Clearance Assessed through Induction (IND) and Consolidation (CONS) Is Associated with Improved Overall Survival (OS) in Newly Diagnosed (nd) FLT3 -ITD+ AML Patients (pts)

Alexander Perl, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E Rohrbach, Ken C N Chang, Li Liu, Yasser Mostafa Kamel, Karima Imadalou, Arnaud Lesegretain, Jorge Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F Schlenk, Mark J. Levis
Journal: Blood
Blood (2023) 142 (Supplement 1): 832.
https://doi.org/10.1182/blood-2023-186785
Published: 2023
Journal Articles

A Highly Successful Model to Decrease Racial Disparities and Increase Access to Autologous Transplants Among African Americans with Multiple Myeloma - Outreach and Satellite Transplant Clinics

Anand Jillella, Danielle Bradshaw, Mohammad Mian, Jorge Cortes, Amany R. Keruakous, Ayushi Chauhan, Locke Johnson Bryan, Molly Denlinger, Vamsi K. Kota
Journal: Blood
Blood (2023) 142 (Supplement 1): 4969.
https://doi.org/10.1182/blood-2023-191069
Published: 2023