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Naveen Pemmaraju
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Journal Articles

Preclinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms transformed to AML

Warren Fiskus, Christopher P Mill, Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Andrew Dunbar, Christine Birdwell, John A Davis, Kaberi Das, Hanxi Hou, Taghi Manshouri, Antrix Jain, Anna Malovannaya, Kevin Philip, Noor Alhamadani, Alicia Matthews, Katie Lin, Lauren Flores, Sanam Loghavi, Courtney D. DiNardo, Xiaoping Su, Raajit K. Rampal, Kapil N Bhalla
Journal: Blood
Blood blood.2024026388.
https://doi.org/10.1182/blood.2024026388
Published: 2024
Includes: Supplemental data
Journal Articles

Proposals for revised International Working Group–European LeukemiaNet criteria for anemia response in myelofibrosis

Brief Report
Ayalew Tefferi, Giovanni Barosi, Francesco Passamonti, Juan-Carlos Hernandez-Boluda, Prithviraj Bose, Konstanze Döhner, Martin Ellis, Naseema Gangat, Jacqueline S. Garcia, Heinz Gisslinger, Jason Gotlib, Paola Guglielmelli, Vikas Gupta, Claire Harrison, Elizabeth O. Hexner, Gabriela S. Hobbs, Jean-Jacques Kiladjian, Steffen Koschmieder, Nicolaus Kroger, Andrew T. Kuykendall, Giuseppe G. Loscocco, John Mascarenhas, Lucia Masarova, Ruben Mesa, Barbara Mora, Olatoyosi Odenike, Stephen T. Oh, Animesh Pardanani, Anand Patel, Naveen Pemmaraju, Alessandro Rambaldi, Raajit Rampal, Shireen Sirhan, Natasha Szuber, Moshe Talpaz, Pankit J. Vachhani, Alessandro M. Vannucchi, Tiziano Barbui
Journal: Blood
Blood (2024) 144 (17): 1813–1820.
https://doi.org/10.1182/blood.2024025802
Published: 2024
Journal Articles

How I treat Blastic Plasmacytoid Dendritic Cell Neoplasm

Mohamed A Kharfan-Dabaja, Andrew A. Lane, Naveen Pemmaraju
Journal: Blood
Blood blood.2024024262.
https://doi.org/10.1182/blood.2024024262
Published: 2024
Journal Articles

Moving toward disease modification in polycythemia vera

Jan Philipp Bewersdorf, Joan How, Lucia Masarova, Prithviraj Bose, Naveen Pemmaraju, John Mascarenhas, Raajit K. Rampal
Journal: Blood
Blood (2023) 142 (22): 1859–1870.
https://doi.org/10.1182/blood.2023021503
Published: 2023
Journal Articles

Venetoclax abrogates the prognostic impact of splicing factor gene mutations in newly diagnosed acute myeloid leukemia

Clinical Trials & Observations
Jayastu Senapati, Samuel Urrutia, Sanam Loghavi, Nicholas J. Short, Ghayas C. Issa, Abhishek Maiti, Hussein A. Abbas, Naval G. Daver, Naveen Pemmaraju, Sherry Pierce, Kelly S. Chien, Koji Sasaki, Tapan M. Kadia, Danielle E. Hammond, Gautam Borthakur, Keyur Patel, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, Courtney D. DiNardo
Journal: Blood
Blood (2023) 142 (19): 1647–1657.
https://doi.org/10.1182/blood.2023020649
Published: 2023
Includes: Supplemental data
Journal Articles

Prevalence of Second Cancers in Patients with Polycythemia Vera (PV): A Retrospective Analysis of US Real-World Claims Data

Naveen Pemmaraju, Alina Markova, Lucia Masarova, Nancy Reaven, Susan Funk, Pedro Oyuela, Frank Valone, Phil Dinh, Lucy Bellamy, Nikita Modi, Arturo Molina, Suneel Gupta
Journal: Blood
Blood (2023) 142 (Supplement 1): 3190.
https://doi.org/10.1182/blood-2023-180045
Published: 2023
Journal Articles

Ibrutinib, Fludarabine, Cyclophosphamide and Obinutuzumab (iFCG) for Firstline Treatment of Patients with CLL with Mutated IGHV and without Del(17p)/ TP53 Mutation: Six-Year Follow-up Analyses

Nitin Jain, Philip Thompson, Akhil Jain, Jan A. Burger, Alessandra Ferrajoli, Jayastu Senapati, Koichi Takahashi, Mahesh Swaminathan, Zeev Estrov, Gautam Borthakur, Prithviraj Bose, Tapan M. Kadia, Naveen Pemmaraju, Koji Sasaki, Divyam Bansal, Marina Y. Konopleva, Elias Jabbour, Naveen Garg, Xuemei Wang, Rashmi Kanagal-Shamanna, Keyur P. Patel, Wei Wang, Sa A. Wang, Jeffrey L. Jorgensen, Wanda Lopez, Ana Ayala, William Plunkett, Varsha Gandhi, Hagop M. Kantarjian, Susan M. O'Brien, Michael J. Keating, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 3267.
https://doi.org/10.1182/blood-2023-188084
Published: 2023
Journal Articles

Transform-1: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, International Phase 3 Study of Navitoclax in Combination with Ruxolitinib Versus Ruxolitinib Plus Placebo in Patients with Untreated Myelofibrosis

Naveen Pemmaraju, Adam J Mead, Tim CP Somervaille, James K McCloskey, Francesca Palandri, Steffen Koschmieder, David Lavie, Brian Leber, Su-Peng Yeh, Maria Teresa Gómez-Casares, Emanuele Ammatuna, Ho-Jin Shin, Keita Kirito, Eric Jourdan, Timothy Devos, Hun S Chuah, Atanas Radinoff, Andrija Bogdanovic, Rastislav Moskal, Qi Jiang, Avijeet S Chopra, Elektra Papadopoulos, Jalaja Potluri, Francesco Passamonti
Journal: Blood
Blood (2023) 142 (Supplement 1): 620.
https://doi.org/10.1182/blood-2023-173509
Published: 2023
Journal Articles

Pivekimab Sunirine (PVEK, IMGN632), a CD123-Targeting Antibody-Drug Conjugate, in Combination with Azacitidine and Venetoclax in Patients with Newly Diagnosed Acute Myeloid Leukemia

Naval Daver, Pau Montesinos, Jessica K. Altman, Eunice S. Wang, Giovanni Martinelli, Gail J. Roboz, Kebede Begna, Paresh Vyas, Monia Lunghi, Uwe Platzbecker, Patrick W. Burke, Roland B. Walter, Anjali S. Advani, Sylvain Garciaz, Lauris Gastaud, David A Sallman, Naveen Pemmaraju, Laura Torres, Yasmin Abaza, Onyee Chan, Hagop M. Kantarjian, Benjamin Oshrine, Yining Du, Kara Malcolm, Kendra Sweet
Journal: Blood
Blood (2023) 142 (Supplement 1): 2906.
https://doi.org/10.1182/blood-2023-173413
Published: 2023
Journal Articles

Prospective Pharmacokinetic Evaluation of Venetoclax (VEN) in AML Demonstrates Significant and Variable Drug Interactions with Azole Antifungals That Increase Ven Exposure, Reduce Clearance, and Necessitate Re-Evaluation of Dose Adjustments

Jitesh Kawedia, Caitlin R Rausch, Xiaoqian Li, Courtney D. DiNardo, Farhad Ravandi, Naval Daver, Gautam Borthakur, Naveen Pemmaraju, Patrick K Reville, Nicholas J. Short, Elias Jabbour, Guillermo Garcia-Manero, Hagop M. Kantarjian, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 2885.
https://doi.org/10.1182/blood-2023-180491
Published: 2023
Journal Articles

Azacitidine Plus Venetoclax Maintenance in Acute Myeloid Leukemia Produces Sustained Remissions with Low Toxicity: Results of a Phase 2 Study

Alexandre Bazinet, Hagop M. Kantarjian, Gautam Borthakur, Musa Yilmaz, Prithviraj Bose, Elias Jabbour, Yesid Alvarado Valero, Kelly S. Chien, Naveen Pemmaraju, Koichi Takahashi, Nicholas J. Short, Naval Daver, Ghayas C. Issa, Nitin Jain, Danielle E. Hammond, Debra Bull-Linderman, Courtney D. DiNardo, Jan A. Burger, Alessandra Ferrajoli, Guillermo Montalban-Bravo, Koji Sasaki, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 2884.
https://doi.org/10.1182/blood-2023-172882
Published: 2023
Journal Articles

Tagraxofusp in Combination with Azacitidine and Venetoclax in Newly Diagnosed CD123+ Acute Myeloid Leukemia, Expansion Cohort of a Phase 1b Multicenter Trial

Andrew A. Lane, Jacqueline S. Garcia, Evangeline G. Raulston, Jada L. Garzon, Ilene Galinsky, Emilie W. Baxter, Rebecca Leonard, Daniel J. DeAngelo, Marlise R. Luskin, Christopher R. Reilly, Maximilian Stahl, Richard M Stone, Rahul Vedula, Martha Wadleigh, Eric S. Winer, Tariq Mughal, Christopher Brooks, Ira V. Gupta, Kristen E. Stevenson, Donna S. Neuberg, Siyang Ren, Marina Y. Konopleva, Anthony Stein, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4277.
https://doi.org/10.1182/blood-2023-180010
Published: 2023
Journal Articles

Influence of Co-Mutational Patterns in Disease Phenotype and Clinical Outcomes of Chronic Myelomonocytic Leukemia

Guillermo Montalban-Bravo, David Swanson, Rashmi Kanagal-Shamanna, Juan Jose Rodriguez-Sevilla, Danielle E. Hammond, Kelly S. Chien, Koji Sasaki, Elias Jabbour, Courtney D. DiNardo, Koichi Takahashi, Nicholas J. Short, Ghayas C. Issa, Naveen Pemmaraju, Tapan M. Kadia, Farhad Ravandi, Naval Daver, Gautam Borthakur, Sanam Loghavi, Sherry Pierce, Carlos E. Bueso-Ramos, Hagop M. Kantarjian, Guillermo Garcia-Manero
Journal: Blood
Blood (2023) 142 (Supplement 1): 4601.
https://doi.org/10.1182/blood-2023-178061
Published: 2023
Journal Articles

Validation of the Prognostic Risk Signatures for Older Patients with Acute Myeloid Leukemia Treated with Hypomethylating Agents and Venetoclax

Alex Bataller, Alexandre Bazinet, Courtney D. DiNardo, Gautam Borthakur, Nicholas J. Short, Elias Jabbour, Koichi Takahashi, Naval Daver, Ghayas C. Issa, Naveen Pemmaraju, Nitin Jain, Guillermo Montalban-Bravo, William G. Wierda, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M. Kantarjian, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 4228.
https://doi.org/10.1182/blood-2023-182841
Published: 2023
Journal Articles

A Phase II Study of Low-Intensity Chemotherapy (Mini-Hyper-CVD) and Ponatinib Followed By Blinatumomab and Ponatinib in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Wei-Ying Jen, Elias Jabbour, Fadi G. Haddad, Lewis Nasr, Nicholas J. Short, Marianne Zoghbi, Cedric Nasnas, Ghayas C. Issa, Musa Yilmaz, Naval Daver, Naveen Pemmaraju, Lucia Masarova, Farhad Ravandi, Nitin Jain, Wuliamatu Deen, Christopher Loiselle, Lourdes Waller, Glenda Banks, Rebecca Garris, Hagop M. Kantarjian
Journal: Blood
Blood (2023) 142 (Supplement 1): 2868.
https://doi.org/10.1182/blood-2023-182997
Published: 2023
Journal Articles

Single-Cell Characterization of TP53-Mutated AML Patients Treated with Frontline Azacitidine, Venetoclax, and Magrolimab Reveals Mechanisms of Response and Resistance

Poonam N Desai, Bofei Wang, Patrick K Reville, Fatima Z Jelloul, Pamella Borges, Jayastu Senapati, Micah Castillo, Preethi Gunaratne, Naveen Pemmaraju, Tapan M. Kadia, Farhad Ravandi, Guillermo Garcia-Manero, Naval Daver, Hussein A Abbas
Journal: Blood
Blood (2023) 142 (Supplement 1): 64.
https://doi.org/10.1182/blood-2023-187307
Published: 2023
Journal Articles

Phase I/II Study of Quizartinib, Venetoclax, and Decitabine Triple Combination in FLT3-ITD Mutated AML

Musa Yilmaz, Muharrem Muftuoglu, Courtney D. DiNardo, Tapan M. Kadia, Marina Y. Konopleva, Gautam Borthakur, Naveen Pemmaraju, Nicholas J. Short, Yesid Alvarado Valero, Abhishek Maiti, Lucia Masarova, Guillermo Montalban-Bravo, Carissa Jurisprudencia, Allison Pike, Sanam Loghavi, Keyur P. Patel, Guilin Tang, Jairo Matthews, Steven M. Kornblau, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi, Michael Andreeff, Naval Daver
Journal: Blood
Blood (2023) 142 (Supplement 1): 158.
https://doi.org/10.1182/blood-2023-186699
Published: 2023
Journal Articles

Early Results of the Phase I/II Study Investigating the All-Oral Combination of the Menin Inhibitor Revumenib (SNDX-5613) with Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

Ghayas C. Issa, Branko Cuglievan, Courtney D. DiNardo, Nicholas J. Short, David McCall, Amber Gibson, Cesar Nunez, Miriam B. Garcia, Michael Roth, Aram Bidikian, Allison Pike, Sheila Tan, Brianna Kammerer, Musa Yilmaz, Tapan M. Kadia, Naveen Pemmaraju, Maro Ohanian, Naval Daver, Elias Jabbour, Gautam Borthakur, Farhad Ravandi, Guillermo Garcia-Manero, Michael Andreeff, Hagop M. Kantarjian
Journal: Blood
Blood (2023) 142 (Supplement 1): 58.
https://doi.org/10.1182/blood-2023-182337
Published: 2023
Journal Articles

Patient Characteristics and Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Muzaffar H. Qazilbash, Hina N. Khan, Denái R. Milton, Oren Pasvolsky, Mark R. Tanner, Uday R. Popat, Partow Kebriaei, Chitra Hosing, Issa F. Khouri, Katayoun Rezvani, Yago Nieto, Betul Oran, Samer A. Srour, Neeraj Y. Saini, Amanda L. Olson, Sairah Ahmed, Gheath Alatrash, Gabriela Rondon, Marina Y. Konopleva, Richard E. Champlin, Elizabeth J. Shpall, Qaiser Bashir, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4988.
https://doi.org/10.1182/blood-2023-181031
Published: 2023
Journal Articles

CPX-351 with Venetoclax in Patients with Relapsed/Refractory Acute Myeloid Leukemia: Results of a Phase Ib Study

Alex Bataller, Alexandre Bazinet, Gautam Borthakur, Nicholas J. Short, Elias Jabbour, Koichi Takahashi, Naval Daver, Ghayas C. Issa, Courtney D. DiNardo, Naveen Pemmaraju, Nitin Jain, Guillermo Montalban-Bravo, William G. Wierda, Farhad Ravandi, Hagop M. Kantarjian, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 4259.
https://doi.org/10.1182/blood-2023-181786
Published: 2023