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Journal Articles

Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy

Available to Purchase
Sven Turkalj, Felix A. Radtke, Bilyana Stoilova, Rabea Mecklenbrauck, Angus J. Groom, Niels Asger Jakobsen, Curtis A. Lachowiez, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Zhihong Zeng, Sanam Loghavi, Jennifer Marvin-Peek, Verena Körber, Farhad Ravandi, Ghayas C. Issa, Tapan M. Kadia, Vasiliki Symeonidou, Anne P. de Groot, Hagop M Kantarjian, Koichi Takahashi, Marina Konopleva, Courtney D. DiNardo, Paresh Vyas
Journal: Blood
Blood blood.2024027948.
https://doi.org/10.1182/blood.2024027948
Published: 2025
Includes: Supplemental data
Journal Articles

BLAST: a globally applicable and molecularly versatile survival model for chronic myelomonocytic leukemia

Available to Purchase
Ayalew Tefferi, Saubia Fathima, Maymona Abdelmagid, Ali Khalid A. Alsugair, Fnu Aperna, Mahsa Rezasoltani, Muhammad Yousuf, Anuya Natu, Clifford M. Csizmar, Mark Gurney, Terra L. Lasho, Christy M. Finke, Rashmi Kangal-Shamanna, Danielle Hammond, Kelly Chien, Alexandre Bazinet, Courtney D. DiNardo, Tapan M. Kadia, Abhishek A. Mangaonkar, Naval Daver, Animesh Pardanani, Gautam Borthakur, Cinthya Zepeda-Mendoza, Kaaren K. Reichard, Rong He, Sanam Loghavi, Francesco Passamonti, Farhad Ravandi, Koji Sasaki, Dirk R. Larson, Guillermo Garcia-Manero, Francesco Onida, Naseema Gangat, Guillermo Montalban-Bravo, Mrinal M. Patnaik
Journal: Blood
Blood (2025) 146 (7): 874–886.
https://doi.org/10.1182/blood.2024027170
Published: 2025
Includes: Supplemental data
Journal Articles

Blood-based proteomic profiling identifies OSMR as a novel biomarker of AML outcomes

Open Access
Patrick K. Reville, Bofei Wang, Jennifer Marvin-Peek, Bin Yuan, Yu-An Kuo, Araceli Garza, Jessica Root, Wei Qiao, Andrea Arruda, Ivo Veletic, Yiwei Liu, Nicholas J. Short, Courtney D. DiNardo, Tapan M. Kadia, Naval G. Daver, Philip L. Lorenzi, Koji Sasaki, Steven Kornblau, Mark D. Minden, Farhad Ravandi, Hagop M. Kantarjian, Hussein A. Abbas
Journal: Blood
Blood (2025) 145 (25): 3015–3029.
https://doi.org/10.1182/blood.2024027244
Published: 2025
Includes: Supplemental data
Journal Articles

Results of a Phase I/II Study of Tagraxofusp in Combination with Decitabine for Patients with Myelodysplastic/Myeloproliferative Neoplasms and Higher Risk Myelodysplastic Syndromes

Free
Mehmet Sevki Uyanik, Guillermo Garcia-Manero, Abhishek Maiti, Farhad Ravandi, Kelly S. Chien, Danielle Hammond, Alexandre Bazinet, Heather Schneider, Stephany Hendrickson, Sherry Pierce, Hagop M. Kantarjian, Naveen Pemmaraju, Guillermo Montalban-Bravo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1842.
https://doi.org/10.1182/blood-2024-207503
Published: 2024
Journal Articles

A Phase II Trial of Azacitidine with Ipilimumab, Nivolumab, or Ipilimumab and Nivolumab in Previously Untreated Myelodysplastic Syndrome

Free
Ian M. Bouligny, Guillermo Montalban-Bravo, Koji Sasaki, Naval Daver, Elias Jabbour, Yesid Alvarado Valero, Courtney D. DiNardo, Farhad Ravandi, Gautam Borthakur, Prithviraj Bose, Naveen Pemmaraju, Steven M. Kornblau, Tapan M. Kadia, Lucia Masarova, Koichi Takahashi, Michael Andreeff, Alexandre Bazinet, Hui Yang, Rashmi Kanagal-Shamanna, Chitra Hosing, Sherry Pierce, Meghan Anne Meyer, Xuelin Huang, Guillermo Garcia-Manero
Journal: Blood
Blood (2024) 144 (Supplement 1): 4601.
https://doi.org/10.1182/blood-2024-204040
Published: 2024
Journal Articles

Characteristics and Outcomes of Patients (pts) with Acute Myeloid Leukemia (AML) and FLT3 -Tyrosine Kinase Domain (TKD) Mutations

Free
Sankalp Arora, Musa Yilmaz, Wei-Ying Jen, Nicholas J. Short, Sanam Loghavi, Tapan M. Kadia, Courtney D. DiNardo, Gautam Borthakur, Indraneel Deshmukh, Ghayas C. Issa, Joseph E. Jabbour, Naveen Pemmaraju, Michael Andreeff, Koichi Takahashi, Kapil N. Bhalla, Hussein A. Abbas, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 841.
https://doi.org/10.1182/blood-2024-204042
Published: 2024
Journal Articles

Blinatumomab and Ponatinib for Adults with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Updated Results and Predictors of Relapse

Free
Nicholas J. Short, Hagop Kantarjian, Nitin Jain, Koichi Takahashi, Ken Furudate, Jayastu Senapati, Fadi G. Haddad, Omer Karrar, Tapan M. Kadia, Kelly S. Chien, Koji Sasaki, Eitan Kugler, Rebecca Garris, Farhad Ravandi, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 837.
https://doi.org/10.1182/blood-2024-206602
Published: 2024
Journal Articles

Phase II Study of Cladribine with Low Dose Cytarabine and Venetoclax Alternating with Azacytidine and Venetoclax for Newly Diagnosed Acute Myeloid Leukemia

Free
Alex Bataller, Hagop M. Kantarjian, Alexandre Bazinet, Jayastu Senapati, Gautam Borthakur, Nicholas J. Short, Elias Jabbour, Koichi Takahashi, Naval Daver, Ghayas C. Issa, Courtney D. DiNardo, Naveen Pemmaraju, Nitin Jain, Guillermo Montalban-Bravo, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 56.
https://doi.org/10.1182/blood-2024-202620
Published: 2024
Journal Articles

A Phase I/II Study of Mini-Hyper-CVD, Venetoclax and Navitoclax in Patients with Relapsed/Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Free
Nicholas J. Short, Hagop Kantarjian, Nitin Jain, Jayastu Senapati, Fadi G. Haddad, Omer Karrar, Kelly S. Chien, Eitan Kugler, Adaeze Elechi, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2024-206487
Published: 2024
Journal Articles

Phase II Study of Inotuzumab Ozogamicin for the Treatment of Measurable Residual Disease-Positive B-Cell Acute Lymphoblastic Leukemia: 3-Year Update

Free
Fadi G. Haddad, Hagop M. Kantarjian, Nicholas J. Short, Jayastu Senapati, Nitin Jain, Koji Sasaki, Jeffrey L. Jorgensen, Joseph E. Jabbour, Sa A. Wang, Yesid Alvarado Valero, Xuemei Wang, Alessandra Ferrajoli, Diane Habib, Jan A. Burger, Courtney D. DiNardo, Zena Komrokji, Lucia Masarova, Tapan M. Kadia, Guillermo Garcia-Manero, Farhad Ravandi, Rebecca Garris, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4194.
https://doi.org/10.1182/blood-2024-210642
Published: 2024
Journal Articles

A Phase I Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with High Risk or Refractory/Relapsed Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Free
Gheath Alatrash, Cristina Knape, Laura Whited, Dawen Sui, Cara L Haymaker, Jason Yeh, Megan Marcotulli, Pariya Sukhumalchandra, Lisa St. John, Hsinyi Lu, Daniela E. Duenas, Ignacio Wistuba, Julia Mendoza Perez, Beatriz Sanchez Espiridion, Roland L. Bassett, Tapan M. Kadia, Courtney D. DiNardo, Farhad Ravandi, Jeremy Ramdial, Rohtesh S. Mehta, Amin M. Alousi, Betul Oran, Issa F. Khouri, Qaiser Bashir, Chitra Hosing, Muzaffar H. Qazilbash, Jin S. Im, Partow Kebriaei, Pavan Bachireddy, Jeffrey J. Molldrem, Jeffrey L. Jorgensen, Sa A. Wang, Wei WANG, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2024-211343
Published: 2024
Journal Articles

Phase 1b/2 Study of Decitabine and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Olutasidenib for Patients with Relapsed/Refractory AML, High Risk MDS, or Newly Diagnosed AML Not Eligible for Chemotherapy with an IDH1 Mutation

Free
Courtney D. DiNardo, Kelly S. Chien, Jillian Mullin, Danielle Hammond, Jeremy Ramdial, Tapan M. Kadia, Fadi G. Haddad, Musa Yilmaz, Koji Sasaki, Ghayas C. Issa, Koichi Takahashi, Elizabeth J. Shpall, Farhad Ravandi, Naval Daver, Hagop Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1527.2.
https://doi.org/10.1182/blood-2024-208771
Published: 2024
Journal Articles

A Phase I/II Study of Gilteritinib and Momelotinib for Patients with Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia: A Trial in Progress

Free
Nicholas J. Short, Farhad Ravandi, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Tapan M. Kadia, Musa Yilmaz, Ghayas C. Issa, Regina Abramova, Araceli Isabella Garza, Hagop M. Kantarjian, Hussein A. Abbas
Journal: Blood
Blood (2024) 144 (Supplement 1): 4288.1.
https://doi.org/10.1182/blood-2024-200923
Published: 2024
Journal Articles

Performance of the Molecular International Prognostic Scoring System (IPSS-M) in Myelodysplastic Syndromes Treated with Hypomethylating Agent-Based Therapy: A Multicenter Analysis

Free
Kelly S. Chien, Ziyi Li, Luca Lanino, Najla H. Al Ali, Samuel Urrutia, Rashmi Kanagal-Shamanna, Ahmed Abdelhakeem, Tareq Abuasab, Emmanuel Almanza, Georgina Gener-Ricos, Alex Bataller, Alexandre Bazinet, Alessia Campagna, Giulia Maggioni, Eric Padron, Zhuoer Xie, Guillermo Montalban-Bravo, Nicholas J. Short, Elias Jabbour, Tapan M. Kadia, Farhad Ravandi, Gautam Borthakur, Danielle Hammond, Mahesh Swaminathan, Koji Sasaki, Xiao Qin Dong, Sherry Pierce, David Sallman, Hagop M. Kantarjian, Matteo Giovanni Della Porta, Guillermo Garcia-Manero, Rami S. Komrokji
Journal: Blood
Blood (2024) 144 (Supplement 1): 4584.
https://doi.org/10.1182/blood-2024-210646
Published: 2024
Journal Articles

Combination of CPX-351 and Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Acute Myeloid Leukemia and Post Hypomethylating Agent (HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS)

Free
Jayastu Senapati, Farhad Ravandi, Emmanuel Almanza, Tapan M. Kadia, Guillermo Montalban-Bravo, Stefan Faderl, Koji Sasaki, Nicholas J. Short, Naval Daver, Courtney D. DiNardo, Lucia Masarova, Alessandra Ferrajoli, Fadi G. Haddad, Elias Jabbour, Gautam Borthakur, Sheila Tan, Sherry Pierce, Guillermo Garcia-Manero, Michael Andreeff, Yesid Alvarado Valero
Journal: Blood
Blood (2024) 144 (Supplement 1): 2903.
https://doi.org/10.1182/blood-2024-207962
Published: 2024
Journal Articles

A Phase II Study of Cladribine, Idarubicin, and Cytarabine (CLIA) in Combination with Gilteritinib for Patients with Newly Diagnosed FLT3 -Mutated Acute Myeloid Leukemia

Free
Hannah Goulart, Hagop M. Kantarjian, Naval Daver, Musa Yilmaz, Guillermo Garcia-Manero, Kelly S. Chien, Jan A. Burger, Naveen Pemmaraju, Courtney D. DiNardo, Nicholas J. Short, Guillermo Montalban-Bravo, Abhishek Maiti, Danielle Hammond, Ghayas C. Issa, Elias Jabbour, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 2901.
https://doi.org/10.1182/blood-2024-205340
Published: 2024
Journal Articles

Fully Oral Combination of Decitabine/Cedazuridine (ASTX727) Plus Venetoclax for the Treatment of Newly Diagnosed Acute Myeloid Leukemia in Patients Ineligible for Intensive Chemotherapy

Free
Alexandre Bazinet, Guillermo Garcia-Manero, Alex Bataller, Yesid Alvarado Valero, Musa Yilmaz, Elias Jabbour, Guillermo Montalban-Bravo, Naveen Pemmaraju, Ghayas C. Issa, Nicholas J. Short, Tapan M. Kadia, Nitin Jain, Lucia Masarova, Naval Daver, Danielle Hammond, Gautam Borthakur, Abhishek Maiti, Koichi Takahashi, Kelly S. Chien, Steven M. Kornblau, Hussein A. Abbas, Maro Ohanian, Jayastu Senapati, Courtney D. DiNardo, Hagop M. Kantarjian, Farhad Ravandi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2896.
https://doi.org/10.1182/blood-2024-198541
Published: 2024
Journal Articles

Clinical Outcomes Using Frontline “Triplet” Regimens for Newly Diagnosed IDH -Mutated Acute Myeloid Leukemia (AML): A Pooled Analysis of Two Phase Ib/2 Clinical Trials

Free
Jennifer Marvin-Peek, Himachandana Atluri, Nicholas J. Short, Abhishek Maiti, Koichi Takahashi, Sanam Loghavi, Curtis A Lachowiez, Yesid Alvarado Valero, Guillermo Montalban-Bravo, Koji Sasaki, Fadi G. Haddad, Ghayas C. Issa, Lucia Masarova, Hussein A. Abbas, Michael Andreeff, Gautam Borthakur, Jillian Mullin, George Donovan Tippett, Kelly S. Chien, Danielle Hammond, Jo Ishizawa, Nitin Jain, Patrick K. Reville, Mahesh Swaminathan, Musa Yilmaz, Naval Daver, Tapan M. Kadia, Farhad Ravandi, Guillermo Garcia-Manero, Hagop M. Kantarjian, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 2883.
https://doi.org/10.1182/blood-2024-200387
Published: 2024
Journal Articles

Myeloid Progenitor Cells with Preleukemic Immunophenotypes Are Common in Myelodysplasia-Related and NPM1- mutated Acute Myeloid Leukemia and Should Not be Interpreted As Measurable Residual Disease

Free
Sanam Loghavi, Sa A. Wang, Wei-Ying Jen, Wei Wang, Hong Fang, Shaoying Li, Sofia A. Garces, Andres E Quesada, Jie Xu, Chi Young Ok, Shimin Hu, Jeffrey L. Jorgensen, Guilin Tang, Cedric Nasnas, Omer Karrar, Ghayas C. Issa, Naval Daver, Courtney D. DiNardo, Tapan M. Kadia, Hagop M. Kantarjian, L. Jeffrey Medeiros, Farhad Ravandi, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 4336.
https://doi.org/10.1182/blood-2024-209462
Published: 2024
Journal Articles

CNS Involvement in Adult Patients with B-Cell Acute Lymphoblastic Leukemia

Free
Susan Y. Wu, Koji Sasaki, Penny Q. Fang, Nicholas J. Short, Jillian R. Gunther, Wenli Dong, Ethan P. Damron, Lewis F. Nasr, David R. Boyce, Abhishek Maiti, Chelsea C. Pinnix, Ghayas C. Issa, Nitin Jain, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Partow Kebriaei, Bouthaina S. Dabaja
Journal: Blood
Blood (2024) 144 (Supplement 1): 4182.
https://doi.org/10.1182/blood-2024-209393
Published: 2024