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Journal Articles

Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial

Blood (2023) 142 (20): 1697–1707.

https://doi.org/10.1182/blood.2023020630

Published: 2023

Includes: Supplemental data

Journal Articles

GATA1 Target Gene CSF2RB Is Functionally Coupled to MPL and Marks a TPO-Dependent Preleukemic TAM Cell Population Sustained By the Fetal Liver but Not Bone Marrow

David Cruz Hernandez, Nicolas Papadopoulos, Elise Sepulchre, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Leila Varghese, Gabriel Levy, Irene Roberts, Stefan N Constantinescu, Paresh Vyas

Blood (2023) 142 (Supplement 1): 404.

https://doi.org/10.1182/blood-2023-174449

Published: 2023

Journal Articles

Single Cell Characterisation of Transcriptional Programmes of Responsive and Resistant Leukaemic Progenitors in IDH2 -Mutant Acute Myeloid Leukaemia in the AG221-AML-005 Study

Prodromos Chatzikyriakou, Douglas RA Silveira, Maria del Pilar Casares Aláez, Batchimeg Usukhbayar, Marlen Metzner, Paresh Vyas, Anita K. Gandhi, Alberto Risueño, Maroof Hasan, Lynn Quek

Blood (2022) 140 (Supplement 1): 3414–3415.

https://doi.org/10.1182/blood-2022-163717

Published: 2022

Journal Articles

Genotyping of Multiple Genomic Loci with Chromatin Accessibility Profiling in Single Cells Links Clonal Hierarchy with Epigenetic Variation in Acute Myeloid Leukemia

Sven Turkalj, Niels Asger Jakobsen, Angus Groom, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Kevin Clark, E. Ravza Gür, Lance D. Hentges, Paul Sopp, James O.J. Davies, Jim R. Hughes, Paresh Vyas

Blood (2022) 140 (Supplement 1): 1193–1194.

https://doi.org/10.1182/blood-2022-163139

Published: 2022

Journal Articles

Single-Cell Analysis of Human Clonal Hematopoiesis Identifies Distinct Impact of DNMT3A and TET2 mutations on Hematopoietic Differentiation

Niels Asger Jakobsen, Sven Turkalj, Bilyana Stoilova, Marlen Metzner, Rachel Moore, Batchimeg Usukhbayar, Mirian Angulo Salazar, Alison Kennedy, Simon Newman, Benjamin Kendrick, Adrian Taylor, Rasheed Afinowi-Luitz, Roger Gundle, Bridget Watkins, Kim Wheway, Debra Beazley, Andrew Carr, Paresh Vyas

Blood (2022) 140 (Supplement 1): 2227–2228.

https://doi.org/10.1182/blood-2022-166474

Published: 2022

Journal Articles

Graft Versus Leukaemia (GvL): Identification & Characterisation of Alloreactive Antigens and Cognate T Cell Responses in Acute Myeloid Leukemia

Connor Sweeney, Gerda Mickute, Kinam Gupta, Marlen Metzner, Batchimeg Usukhbayar, Maria Chiara Barbanti, Gavinda Sangha, Ronjon Chakraverty, Persephone Borrow, Nicola Ternette, Ane Ogbe, Maria Aggelakopoulou, Paresh Vyas

Blood (2022) 140 (Supplement 1): 1576–1578.

https://doi.org/10.1182/blood-2022-166918

Published: 2022

Journal Articles

Dynamics of Clonal Hematopoiesis Inferred By Modelling Deep Bulk Whole-Genome Sequencing Data at a Single Time Point

Naser Ansari-Pour, Verena Körber, Niels Asger Jakobsen, Rachel Moore, Nina Claudino, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Simon Newman, Benjamin Kendrick, Adrian Taylor, Rasheed Afinowi-Luitz, Roger Gundle, Bridget Watkins, Kim Wheway, Debra Beazley, Andrew Carr, Paresh Vyas, Thomas Höfer

Blood (2022) 140 (Supplement 1): 5753–5754.

https://doi.org/10.1182/blood-2022-166236

Published: 2022

Journal Articles

Dysregulation of Stem-Progenitor and Differentiation Programmes through Modulation of Bivalent Chromatin Drives Leukemogenesis in Mutant IDH2 Acute Myeloid Leukaemia

Douglas RA RA Silveira, Prodromos Chatzikyriakou, Maria del Pilar Casares Alaez, Sarah Mackie, Roan Hulks, Olena Yavorska, Paulina Siejka-Zielinska, Marlen Metzner, Alastair Smith, Batchimeg Usukhbayar, Virginie Penard-Lacronique, Chunxiao Song, Anita K. Gandhi, Maroof Hasan, Paresh Vyas, Thomas A. Milne, Skirmantas Kriaucionis, Lynn Quek

Blood (2022) 140 (Supplement 1): 8698–8699.

https://doi.org/10.1182/blood-2022-165898

Published: 2022

Journal Articles

A Randomized Comparison of the Fractionated Versus Single Dose Schedule of Gemtuzumab Ozogamicin at Induction with Determinants of Benefit for Older AML Patients: UK NCRI AML18 Trial Results

Blood (2022) 140 (Supplement 1): 532–533.

https://doi.org/10.1182/blood-2022-162245

Published: 2022

Journal Articles

Repressed Chromatin Drives Leukaemogenesis in Mutant IDH2 Acute Myeloid Leukaemia Via Inhibition of Granulocyte Differentiation and Cell Cycle Progression

Douglas RA Silveira, Prodromos Chatzikyriakou, Olena Yavorska, Sarah Mackie, Roan Hulks, Paulina Siejka-Zielinska, Anna Corby, Alastair Smith, Benjamin Brown, Marlen Metzner, Thomas A. Milne, Virginie Penard-Lacronique, Chunxiao Song, Maroof Hasan, Anjan Thakurta, Paresh Vyas, Skirmantas Kriaucionis, Lynn Quek

Blood (2021) 138 (Supplement 1): 3467.

https://doi.org/10.1182/blood-2021-149519

Published: 2021

Journal Articles

A Phase 1b Study of Eltrombopag and Azacitidine in Patients with High Risk Myelodysplastic Syndromes and Related Disorders

Alex Sternberg, MRCP,FRCPath, Rebecca H. Boucher, BSc, MSc, PhD, Helen C Coulthard, BSc, Manoj Raghavan, MBBS, PhD MRCP, FRCPath, Dominic J. Culligan, MD, Aimee Jackson, BSc, MSc, Catherine Cargo, MB, PhD, Mike Dennis, MD, Marlen Metzner, MSc, Rachel Moore, BA, David Bowen, MD, Paresh Vyas, MRCP, FRCP, FRCPath

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-134227

Published: 2020

Journal Articles

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome

David Cruz Hernandez, Marlen Metzner, Anne Pieta de Groot, Batchimeg Usukhbayar, Natalina Elliott, Irene Roberts, Paresh Vyas

Blood (2020) 136 (12): 1460–1465.

https://doi.org/10.1182/blood.2020005610

Published: 2020

Includes: Supplemental data

Journal Articles

Identification of 2 DNA methylation subtypes of Waldenström macroglobulinemia with plasma and memory B-cell features

Damien Roos-Weil, Brian Giacopelli, Marine Armand, Véronique Della-Valle, Hussein Ghamlouch, Camille Decaudin, Marlen Metzner, Junyan Lu, Magali Le Garff-Tavernier, Véronique Leblond, Paresh Vyas, Thorsten Zenz, Florence Nguyen-Khac, Olivier A. Bernard, Christopher C. Oakes

Blood (2020) 136 (5): 585–595.

https://doi.org/10.1182/blood.2020005081

Published: 2020

Includes: Supplemental data

Journal Articles

Modelling the Progression of a Preleukemic Stage to Overt Leukemia in Children with Down Syndrome

Blood (2018) 132 (Supplement 1): 543.

https://doi.org/10.1182/blood-2018-99-116661

Published: 2018

Journal Articles

Clonal Heterogeneity in Differentiation Response and Resistance to the IDH2 Inhibitor Enasidenib in Acute Myeloid Leukemia

Blood (2017) 130 (Supplement 1): 724.

https://doi.org/10.1182/blood.V130.Suppl_1.724.724

Published: 2017

Journal Articles

Mature Analysis of the Prospective Oxford Down Syndrome (DS) Cohort Study: Timing and Clinical Impact of Preleukemic GATA1 Mutations and Lessons for Management of Newborns with DS

Irene Roberts, MD, Neha Bhatnagar, ND, Amelie Chaussade, MD, Laure Nizery, MD, Helen Richmond, RSCN, Natalina Elliott, PhD, Gemma Buck, BSc, Marlen Metzner, MSc, Alison Kennedy, MSc, Catherine Garnett, Kelly Perkins, PhD, Paresh Vyas, DPhil, FRCP, FRCPath, MRCP, MRCPath

Blood (2017) 130 (Supplement 1): 569.

https://doi.org/10.1182/blood.V130.Suppl_1.569.569

Published: 2017

NARROW

Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial

GATA1 Target Gene CSF2RB Is Functionally Coupled to MPL and Marks a TPO-Dependent Preleukemic TAM Cell Population Sustained By the Fetal Liver but Not Bone Marrow

Single Cell Characterisation of Transcriptional Programmes of Responsive and Resistant Leukaemic Progenitors in IDH2 -Mutant Acute Myeloid Leukaemia in the AG221-AML-005 Study

Genotyping of Multiple Genomic Loci with Chromatin Accessibility Profiling in Single Cells Links Clonal Hierarchy with Epigenetic Variation in Acute Myeloid Leukemia

Single-Cell Analysis of Human Clonal Hematopoiesis Identifies Distinct Impact of DNMT3A and TET2 mutations on Hematopoietic Differentiation

Graft Versus Leukaemia (GvL): Identification & Characterisation of Alloreactive Antigens and Cognate T Cell Responses in Acute Myeloid Leukemia

Dynamics of Clonal Hematopoiesis Inferred By Modelling Deep Bulk Whole-Genome Sequencing Data at a Single Time Point

Dysregulation of Stem-Progenitor and Differentiation Programmes through Modulation of Bivalent Chromatin Drives Leukemogenesis in Mutant IDH2 Acute Myeloid Leukaemia

A Randomized Comparison of the Fractionated Versus Single Dose Schedule of Gemtuzumab Ozogamicin at Induction with Determinants of Benefit for Older AML Patients: UK NCRI AML18 Trial Results

Repressed Chromatin Drives Leukaemogenesis in Mutant IDH2 Acute Myeloid Leukaemia Via Inhibition of Granulocyte Differentiation and Cell Cycle Progression

A Phase 1b Study of Eltrombopag and Azacitidine in Patients with High Risk Myelodysplastic Syndromes and Related Disorders

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome

Identification of 2 DNA methylation subtypes of Waldenström macroglobulinemia with plasma and memory B-cell features

Modelling the Progression of a Preleukemic Stage to Overt Leukemia in Children with Down Syndrome

Clonal Heterogeneity in Differentiation Response and Resistance to the IDH2 Inhibitor Enasidenib in Acute Myeloid Leukemia

Mature Analysis of the Prospective Oxford Down Syndrome (DS) Cohort Study: Timing and Clinical Impact of Preleukemic GATA1 Mutations and Lessons for Management of Newborns with DS

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American Society of Hematology

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ASH Publications

American Society of Hematology

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