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Gabriel Levy
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Journal Articles

Modulation of human thrombopoietin receptor conformations uncouples JAK2 V617F-driven activation from cytokine-induced stimulation

Nicolas Papadopoulos, Ajda Pristavec, Audrey Nédélec, Gabriel Levy, Judith Staerk, Stefan N. Constantinescu
Journal: Blood
Blood (2023) 142 (21): 1818–1830.
https://doi.org/10.1182/blood.2022019580
Published: 2023
Includes: Supplemental data
Journal Articles

GATA1 Target Gene CSF2RB Is Functionally Coupled to MPL and Marks a TPO-Dependent Preleukemic TAM Cell Population Sustained By the Fetal Liver but Not Bone Marrow

David Cruz Hernandez, Nicolas Papadopoulos, Elise Sepulchre, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Leila Varghese, Gabriel Levy, Irene Roberts, Stefan N Constantinescu, Paresh Vyas
Journal: Blood
Blood (2023) 142 (Supplement 1): 404.
https://doi.org/10.1182/blood-2023-174449
Published: 2023
Journal Articles

Modulation of the Human Thrombopoietin Receptor Conformation Uncouples JAK2 V617F-Driven from Cytokine-Induced Activation

Nicolas Papadopoulos, Ajda Pristavec, Gabriel Levy, Audrey Nédélec, Judith Staerk, Stefan N. Constantinescu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3878–3879.
https://doi.org/10.1182/blood-2022-166405
Published: 2022
Journal Articles

Canonical Thrombopoietin Receptor Mutants in Myeloproliferative Neoplasms Rely Differently on the Extracellular Domain of the Receptor but Share Similar Mechanisms of Inactivation: An Open Field for the Development of New Therapies

Gabriel Levy, Nicolas Papadopoulos, Christian Pecquet, Jean-Philippe Defour, Emilie Leroy, Nabih Maslah, Bruno Cassinat, Steven Smith, Stefan N Constantinescu
Journal: Blood
Blood (2022) 140 (Supplement 1): 8736–8737.
https://doi.org/10.1182/blood-2022-168663
Published: 2022
Journal Articles

CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag

Francesca Basso-Valentina, Gabriel Levy, Leila N. Varghese, Myriam Oufadem, Benedicte Neven, Charlotte Boussard, Nathalie Balayn, Caroline Marty, William Vainchenker, Isabelle Plo, Paola Ballerini, Stefan N. Constantinescu, Remi Favier, Hana Raslova
Journal: Blood
Blood (2021) 138 (6): 480–485.
https://doi.org/10.1182/blood.2020010567
Published: 2021
Includes: Supplemental data
Journal Articles

MPL mutations in essential thrombocythemia uncover a common path of activation with eltrombopag dependent on W491

Brief Report
Gabriel Levy, Serge Carillo, Benjamin Papoular, Bruno Cassinat, Jean-Marc Zini, Emilie Leroy, Leila N. Varghese, Ilyas Chachoua, Jean-Philippe Defour, Steven O. Smith, Stefan N. Constantinescu
Journal: Blood
Blood (2020) 135 (12): 948–953.
https://doi.org/10.1182/blood.2019003240
Published: 2020
Includes: Supplemental data