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Journal Articles

High frequency of clonal hematopoiesis in Erdheim-Chester disease

Fleur Cohen Aubart, Damien Roos-Weil, Marine Armand, Alice Marceau-Renaut, Jean-François Emile, Nicolas Duployez, Frédéric Charlotte, Stéphanie Poulain, Raphael Lhote, Zofia Hélias-Rodzewicz, Véronique Della-Valle, Olivier Bernard, Karim Maloum, Florence Nguyen-Khac, Jean Donadieu, Zahir Amoura, Omar Abdel-Wahab, Julien Haroche

Blood (2021) 137 (4): 485–492.

https://doi.org/10.1182/blood.2020005101

Published: 2021

Includes: Supplemental data

Journal Articles

Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development

Raksha Shrestha, MD, DiMM, Maie Koichiro, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Olivier Bernard, Hirotaka Matsui, MD PhD, Yaeko Nakajima-Takagi, PhD, Takayasu Kato, MD PhD, Haruhiko Koseki, PhD, Atsushi Iwama, MD PhD, Shigeru Chiba, MD PhD

Blood (2018) 132 (Supplement 1): 1330.

https://doi.org/10.1182/blood-2018-99-112352

Published: 2018

Journal Articles

Genetic Characterization of B-Cell Prolymphocytic Leukemia (B-PLL): A Hierarchical Prognostic Model Involving MYC and TP53 Abnormalities. on Behalf of the Groupe Francophone De Cytogenetique Hematologique (GFCH) and the French Innovative Leukemia Organization (FILO) Group

Blood (2018) 132 (Supplement 1): 943.

https://doi.org/10.1182/blood-2018-99-115085

Published: 2018

Journal Articles

Clonal Heterogeneity in Differentiation Response and Resistance to the IDH2 Inhibitor Enasidenib in Acute Myeloid Leukemia

Blood (2017) 130 (Supplement 1): 724.

https://doi.org/10.1182/blood.V130.Suppl_1.724.724

Published: 2017

Journal Articles

Clonal Evolution in CLL

Simon Bouzy, Marine Armand, Clementine Gabillaud, Elise Chapiro, Nadia Bougacha, Fotini Kostopoulou, PhD, Frederic Davi, MD PhD, Magali Le Garff-Tavernier, Karim Maloum, Veronique Leblond, Veronique Morel, Damien Roos-Weil, Anne Lavaud, Jean Gabarre, Choquet Sylvain, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD

Blood (2017) 130 (Supplement 1): 3008.

https://doi.org/10.1182/blood.V130.Suppl_1.3008.3008

Published: 2017

Journal Articles

The Gain of the Short Arm of Chromosome 2 (2pgain) Plays an Important Role in CLL Drug Resistance, and Has to be Systematically Considered before Deciding an Adapted Therapy

Fotini Kostopoulou, PhD, Nadia Bougacha, Clementine Gabillaud, Elise Chapiro, Simon Bouzy, Magali Le Garff-Tavernier, Pharm, PhD, Karim Maloum, Choquet Sylvain, Veronique Leblond, Jean Gabarre, Anne Lavaud, Veronique Morel, Damien Roos-Weil, Madalina Uzunov, Romain Guieze, MD PhD, Olivier Tournilhac, MD PhD, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD

Blood (2017) 130 (Supplement 1): 1729.

https://doi.org/10.1182/blood.V130.Suppl_1.1729.1729

Published: 2017

Journal Articles

AG-120, an Oral, Selective, First-in-Class, Potent Inhibitor of Mutant IDH1, Reduces Intracellular 2HG and Induces Cellular Differentiation in TF-1 R132H Cells and Primary Human IDH1 Mutant AML Patient Samples Treated Ex Vivo

Erica Hansen, Cyril Quivoron, Kim Straley, René M Lemieux, Janeta Popovici-Muller, Hossein Sadrzadeh, Amir T Fathi, Camelia Gliser, Muriel David, Véronique Saada, Jean-Baptiste Micol, Olivier Bernard, Marion Dorsch, Hua Yang, Michael Su, Sam Agresta, Stéphane de Botton, Virginie Penard-Lacronique, Katharine Yen

Blood (2014) 124 (21): 3734.

https://doi.org/10.1182/blood.V124.21.3734.3734

Published: 2014

Journal Articles

AG-221, an Oral, Selective, First-in-Class, Potent IDH2-R140Q Mutant Inhibitor, Induces Differentiation in a Xenotransplant Model

Cyril Quivoron, Muriel David, Kim Straley, Jeremy Travins, Hyeryun Kim, Yue Chen, Dongwei Zhu, Véronique Saada, Olivia Bawa, Paule Opolon, Mélanie Polrot, Jean-Baptiste Micol, Christophe Willekens, Olivier Bernard, Hua Yang, Sam Agresta, Stéphane de Botton, Katharine Yen, Virginie Penard-Lacronique

Blood (2014) 124 (21): 3735.

https://doi.org/10.1182/blood.V124.21.3735.3735

Published: 2014

Journal Articles

TET2 Favors Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Barbara da Costa Reis Monte Mor, Ph.D, Thierry Langlois, Nathalie Droin, Ph.D, Elodie Pronier, Jean-Pierre Le Couédic, Nathalie Auger, M.D., Carole Almire, M.D., Thomas Mercher, PhD, Francois Delhommeau, PharmD, PhD, Debili Najet, Ph.D, Olivier Bernard, Eric Solary, Isabelle Plo, Ph.D, William Vainchenker, MD., Ph.D

Blood (2011) 118 (21): 2418.

https://doi.org/10.1182/blood.V118.21.2418.2418

Published: 2011

Journal Articles

IDH1/2, TET2 and DNMT3A Mutations Are Not Mutually Exclusive in Secondary Acute Myeloid Leukemias,

Olivier Kosmider, Olivier LaRochelle, Marie-Magdelaine Coude, Veronique Mansat-De Mas, Eric Delabesse, Pascale Cornillet-Lefebvre, Odile Blanchet, Christian Recher, Alain Delmer, MD, Sophie Raynaud, Catherine Lacombe, Olivier Bernard, Norbert Ifrah, Francois Dreyfus, Michaela Fontenay

Blood (2011) 118 (21): 3556.

https://doi.org/10.1182/blood.V118.21.3556.3556

Published: 2011

Journal Articles

Novel Mutations: Dissecting Pathogenetic Contribution

William Vainchenker, MD, PhD, Francois Delhommeau, PharmD, PhD, Isabelle Plo, Jean-Luc Villeval, Olivier Bernard

Blood (2010) 116 (21): SCI-34.

https://doi.org/10.1182/blood.V116.21.SCI-34.SCI-34

Published: 2010

Journal Articles

TET2 Mutations in Secondary Acute Myeloid Leukemias: A French Retrospective Study

Olivier Kosmider, Véronique De Mas, Eric Delabesse, Pascale Cornillet-lefevre, Odile Blanchet, Christian Récher, Sophie Raynaud, Catherine Lacombe, Olivier Bernard, Norbert Ifrah, Francois Dreyfus, Michaëla Fontenay on behalf of the GOELAMS

Blood (2010) 116 (21): 176.

https://doi.org/10.1182/blood.V116.21.176.176

Published: 2010

Journal Articles

Analysis of the Ten-Eleven Translocation 2 ( TET2 ) gene in familial myeloproliferative neoplasms

Cécile Saint-Martin, Gwendoline Leroy, François Delhommeau, Gérard Panelatti, Sabrina Dupont, Chloé James, Isabelle Plo, Dominique Bordessoule, Christine Chomienne, André Delannoy, Alain Devidas, Martine Gardembas-Pain, Françoise Isnard, Yves Plumelle, Olivier Bernard, William Vainchenker, Albert Najman, Christine Bellanné-Chantelot, the French Group of Familial Myeloproliferative Disorders

Blood (2009) 114 (8): 1628–1632.

https://doi.org/10.1182/blood-2009-01-197525

Published: 2009

Includes: Supplemental data

Journal Articles

IGH@ Translocations Involving the Pseudoautosomal Region 1 (PAR1) of Both Sex Chromosomes Deregulate the Cytokine Receptor-Like Factor 2 (CRLF2) Gene in B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Lisa J Russell, Melania Capasso, Inga Vater, Anthony V Moorman, Takashi Akasaka, Lana Harder, Olaf Heidenreich, Lee Machado, Stephan Gest, Jonathan C Strefford, Thiruppavai Chandrasekaran, Holger Tönnies, Aneela Majid, Olivier Bernard, Martin JS Dyer, Reiner Siebert, Christine J Harrison

Blood (2008) 112 (11): 787.

https://doi.org/10.1182/blood.V112.11.787.787

Published: 2008

Journal Articles

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

Francois Delhommeau, Sabrina Dupont, Chloe James, MD, PhD, Aline Masse, Jean Pierre le Couedic, Veronique Della Valle, Antonio Alberdi, Philippe Dessen, Michaela Fontenay, Nicole Casadevall, MD, Jean Soulier, MD, PhD, Olivier Bernard, William Vainchenker

Blood (2008) 112 (11): lba-3.

https://doi.org/10.1182/blood.V112.11.lba-3.lba-3

Published: 2008

Journal Articles

OTT-MAL Activates the Notch Signaling Transcription Factor RBPJ and Cooperates with Mutant MPL to Induce Acute Megakaryoblastic Leukemia

Thomas Mercher, Ph.D, Glen D. Raffel, MD, PhD, Sandra A Moore, Melanie G Cornejo, Dominique Baudry-Bluteau, Ph.D, Nicolas Cagnard, Jonathan Jesneck, Yana Pikman, Dana E. Cullen, Ifor Williams, Koichi Akashi, MD, PhD, Hirokazu Shigematsu, Jean-Pierre Bourquin, MD, PhD, Marco Giovannini, MD, PhD, William Vainchenker, Ross L Levine, MD, Benjamin H. Lee, MD, PhD, Olivier Bernard, D. Gary Gilliland

Blood (2008) 112 (11): 508.

https://doi.org/10.1182/blood.V112.11.508.508

Published: 2008

Journal Articles

High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.

Marc Loriaux, Ross Levine, Jeffrey Tyner, Stephan Frohling, Claudia Scholl, Eric Stoffregen, Gerlinde Wernig, Heidi Erickson, Chris Eide, Roland Berger, Olivier Bernard, James Griffin, Richard Stone, Matthew Meyerson, Michael Heinrich, Michael Deininger, Gary Gilliland, Brian Druker

Blood (2007) 110 (11): 886.

https://doi.org/10.1182/blood.V110.11.886.886

Published: 2007

Journal Articles

Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy

Vahid Asnafi, Kheira Beldjord, Marta Libura, Patrick Villarese, Corrine Millien, Paola Ballerini, Emilienne Kuhlein, Marina Lafage-Pochitaloff, Eric Delabesse, Olivier Bernard, Elizabeth Macintyre

Blood (2004) 104 (13): 4173–4180.

https://doi.org/10.1182/blood-2003-11-3944

Published: 2004

Journal Articles

A Molecular Signature of the Transcription Factor GATA1 in Acute Megakaryoblastic Leukemia of Childhood.

Jean-Pierre Bourquin, MD-PhD, Claudia Langebrake, PharmD, Aravind Subramanian, PhD, Xiaochun Li, PhD, Dirk Reinhardt, MD, Olivier Bernard, MD, Christian M. Zwaan, MD-PhD, Henrik Hasle, MD, Martin Schrappe, MD, Todd R. Golub, MD, Stuart H. Orkin, MD

Blood (2004) 104 (11): 1117.

https://doi.org/10.1182/blood.V104.11.1117.1117

Published: 2004

Journal Articles

Homeodomain Expression in AML and T-ALL Cell Lines.

Harry Drabkin, MD, Sharvari Gadgil, BS, Chan Zeng, PhD, Anna Baron, PhD, Olivier Bernard, PhD

Blood (2004) 104 (11): 3369.

https://doi.org/10.1182/blood.V104.11.3369.3369

Published: 2004

NARROW

High frequency of clonal hematopoiesis in Erdheim-Chester disease

Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development

Genetic Characterization of B-Cell Prolymphocytic Leukemia (B-PLL): A Hierarchical Prognostic Model Involving MYC and TP53 Abnormalities. on Behalf of the Groupe Francophone De Cytogenetique Hematologique (GFCH) and the French Innovative Leukemia Organization (FILO) Group

Clonal Heterogeneity in Differentiation Response and Resistance to the IDH2 Inhibitor Enasidenib in Acute Myeloid Leukemia

Clonal Evolution in CLL

The Gain of the Short Arm of Chromosome 2 (2pgain) Plays an Important Role in CLL Drug Resistance, and Has to be Systematically Considered before Deciding an Adapted Therapy

AG-120, an Oral, Selective, First-in-Class, Potent Inhibitor of Mutant IDH1, Reduces Intracellular 2HG and Induces Cellular Differentiation in TF-1 R132H Cells and Primary Human IDH1 Mutant AML Patient Samples Treated Ex Vivo

AG-221, an Oral, Selective, First-in-Class, Potent IDH2-R140Q Mutant Inhibitor, Induces Differentiation in a Xenotransplant Model

TET2 Favors Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

IDH1/2, TET2 and DNMT3A Mutations Are Not Mutually Exclusive in Secondary Acute Myeloid Leukemias,

Novel Mutations: Dissecting Pathogenetic Contribution

TET2 Mutations in Secondary Acute Myeloid Leukemias: A French Retrospective Study

Analysis of the Ten-Eleven Translocation 2 ( TET2 ) gene in familial myeloproliferative neoplasms

IGH@ Translocations Involving the Pseudoautosomal Region 1 (PAR1) of Both Sex Chromosomes Deregulate the Cytokine Receptor-Like Factor 2 (CRLF2) Gene in B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

OTT-MAL Activates the Notch Signaling Transcription Factor RBPJ and Cooperates with Mutant MPL to Induce Acute Megakaryoblastic Leukemia

High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.

Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy

A Molecular Signature of the Transcription Factor GATA1 in Acute Megakaryoblastic Leukemia of Childhood.

Homeodomain Expression in AML and T-ALL Cell Lines.

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