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Jean-Baptiste Micol
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Journal Articles

Mutational Profile and Dynamics of PPM1D -Mutant Clones in the Spectrum of Myeloid Disorders

Jean Pegliasco, David Fandrei, Florence Pasquier, Nathalie Ibrahim, Maria Kfoury, Guillemette Imbert-De-Tremiolles, Nourhan Lizziek, Céline Berthon, Mael Heiblig, Delphine Lebon, Ambroise Marcais, Mathieu Meunier, Ahmad Aljijakli, Emilie Lemasle, Sylvain Chantepie, Cécile Pautas, Pierre-Yves Dumas, Stephanie Haiat, Cyril Quivoron, Ileana antony-Debre, Sophie Cotteret, Raphael Itzykson, Hervé Dombret, Nicolas Duployez, Nathalie Droin, Christophe Marzac, Elsa Bernard, Jean-Baptiste Micol
Journal: Blood
Blood (2023) 142 (Supplement 1): 4064.
https://doi.org/10.1182/blood-2023-189428
Published: 2023
Journal Articles

Long-Term Real-World Experience of CPX-351 in Combined French-Italian Cohorts Identified High Rate of Negative Measurable Residual Disease (MRD) and Prolonged Overall Survival

Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahmé, Sarah Bertoli, Livio Pagano, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Mohamad Mohty, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina Dargenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christian Recher, Norbert Vey, Francesco Grimaldi, Lionel Ades, Roberto Massimo Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 4255.
https://doi.org/10.1182/blood-2023-177951
Published: 2023
Journal Articles

1-Year Data Analysis from a Cancer Center Molecular Tumor Board Dedicated to Clonal Hematopoiesis

Jean-Baptiste Micol, Ahmadreza Arbab, Damien Vasseur, Arnaud Bayle, Mihaela Aldea, Romain Loyaux, Veronique Verge, Veronique Saada, Alice Fievet, Nathalie Auger, Sophie Cotteret, Florence Pasquier, Christophe Willekens, Camille Bigenwald, Cristina Castilla-Llorente, Stephane De Botton, Eric Solary, Elsa Bernard, Etienne Rouleau, Antoine Italiano, Christophe Marzac, Aline Renneville
Journal: Blood
Blood (2023) 142 (Supplement 1): 1322.
https://doi.org/10.1182/blood-2023-186721
Published: 2023
Journal Articles

Therapy Related Myeloid Neoplasms Following PARP Inhibitors : Real-Life Experience

Vincent Marmouset, Justine Decroocq, Sylvain Garciaz, Gabriel Etienne, Amine Belhabri, Sarah Bertoli, Lauris Gastaud, Celestine Simand, Sylvain Chantepie, Madalina Uzunov, Alexis Genthon, Celine Berthon, Edmond Chiche, Pierre-Yves Dumas, Jacques Vargaftig, Géraldine Salmeron, Emilie Lemasle, Emmanuelle Tavernier, Jeremy Delage, Marion Loirat, Nadine Morineau, Felix Blanc-Durand, Patricia Pautier, Veronique Vergé, Nathalie Auger, Myrtille Thomas, Laetitia Stefani, Marion Lepelley, Thomas Boyer, Sylvain Thepot, Marie-Pierre Gourin, Pascal Bourquard, Matthieu Duchmann, Pierre Morice, Mauricette Michallet, Lionel Ades, Pierre Fenaux, Christian Recher, Hervé Dombret, Arnaud Pages, Christophe Marzac, Alexandra Leary, Jean-Baptiste Micol
Journal: Blood
Blood (2022) 140 (Supplement 1): 12335–12338.
https://doi.org/10.1182/blood-2022-163478
Published: 2022
Journal Articles

Reduced Venetoclax Exposition to Seven Days of Azacitidine Is Efficient in Treatment-Naïve Patients with Acute Myeloid Leukemia

Christophe Willekens, Samy Chraibi, Justine Decroocq, Benjamin Carpentier, Delphine Lebon, Sarah Bonnet, Nicolas Gauthier, Arnaud Pagès, Matteo Dragani, Sabine Khalife-Hachem, Jean-Baptiste Micol, Florence Pasquier, Stefan Wickenhauser, Véronique Saada, Véronique Vergé, Ahmadreza Arbab, Christophe Marzac, Laurent Pascal, Damien Roos-Weil, Eric Jourdan, Didier Bouscary, Stéphane de Botton
Journal: Blood
Blood (2022) 140 (Supplement 1): 537–538.
https://doi.org/10.1182/blood-2022-165464
Published: 2022
Journal Articles

Prognostic impact of DDX41 germline mutations in intensively treated acute myeloid leukemia patients: an ALFA-FILO study

Clinical Trials & Observations
Nicolas Duployez, Laëtitia Largeaud, Matthieu Duchmann, Rathana Kim, Julie Rieunier, Juliette Lambert, Audrey Bidet, Lise Larcher, Jean Lemoine, François Delhommeau, Pierre Hirsch, Laurène Fenwarth, Olivier Kosmider, Justine Decroocq, Anne Bouvier, Yannick Le Bris, Marlène Ochmann, Alberto Santagostino, Lionel Adès, Pierre Fenaux, Xavier Thomas, Jean-Baptiste Micol, Claude Gardin, Raphael Itzykson, Jean Soulier, Emmanuelle Clappier, Christian Recher, Claude Preudhomme, Arnaud Pigneux, Hervé Dombret, Eric Delabesse, Marie Sébert
Journal: Blood
Blood (2022) 140 (7): 756–768.
https://doi.org/10.1182/blood.2021015328
Published: 2022
Includes: Supplemental data
Journal Articles

Frequency and Outcome of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with BCR-ABL1 Clonal Hematopoiesis after Blast Clearance: Results from the Graaph-2014 Trial

Rathana KIM, Philippe Rousselot, Jean-Michel Cayuela, Yves Chalandon, Marie Passet, Xavier Thomas, Nicole Straetmans, Patrice Chevallier, Francoise Huguet, Celine Berthon, Georg Stüssi, Sébastien Maury, Sylvain Chantepie, Jean-Baptiste Micol, Isabelle Plantier, Sylvie Chevret, Jean Soulier, Norbert Ifrah, Veronique Lheritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2021) 138 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2021-150126
Published: 2021
Journal Articles

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

CME Clinical Trials & Observations
Raphael Itzykson, Elise Fournier, Céline Berthon, Christoph Röllig, Thorsten Braun, Alice Marceau-Renaut, Cécile Pautas, Olivier Nibourel, Emilie Lemasle, Jean-Baptiste Micol, Lionel Adès, Delphine Lebon, Jean-Valère Malfuson, Lauris Gastaud, Laure Goursaud, Emmanuel Raffoux, Kevin-James Wattebled, Philippe Rousselot, Xavier Thomas, Sylvain Chantepie, Thomas Cluzeau, Hubert Serve, Nicolas Boissel, Christine Terré, Karine Celli-Lebras, Claude Preudhomme, Christian Thiede, Hervé Dombret, Claude Gardin, Nicolas Duployez
Journal: Blood
Blood (2021) 138 (7): 507–519.
https://doi.org/10.1182/blood.2021011103
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic significance of concurrent gene mutations in intensively treated patients with IDH -mutated AML: an ALFA study

CME Clinical Trials & Observations
Matthieu Duchmann, Jean-Baptiste Micol, Nicolas Duployez, Emmanuel Raffoux, Xavier Thomas, Jean-Pierre Marolleau, Thorsten Braun, Lionel Adès, Sylvain Chantepie, Emilie Lemasle, Céline Berthon, Jean-Valère Malfuson, Cécile Pautas, Juliette Lambert, Nicolas Boissel, Karine Celli-Lebras, Denis Caillot, Pascal Turlure, Norbert Vey, Arnaud Pigneux, Christian Recher, Christine Terré, Claude Gardin, Raphaël Itzykson, Claude Preudhomme, Hervé Dombret, Stéphane de Botton
Journal: Blood
Blood (2021) 137 (20): 2827–2837.
https://doi.org/10.1182/blood.2020010165
Published: 2021
Includes: Supplemental data
Journal Articles

Therapy Related Myeloid Neoplasm Post PARP Inhibitors: Potential Clonal Selection.

Jean-Edouard Martin, Sabine Khalife-Hachem, Thomas Grinda, Maria Kfoury, Sylvain Garciaz, Florence Pasquier, MD PhD, Jacques Vargaftig, Madalina Uzunov, MD, Amine Belhabri, MD, Sarah Bertoli, MD PhD, Nathalie Auger, Veronique Saada, Christel Guillouf, Iléana Antony-Debre, PhD, Etienne Rouleau, Flore Salviat, Olivier Caron, Patricia Pautier, Gabriel Etienne, MD PhD, Norbert Vey, MD, Filippo Rosselli, Stephane De Botton, Alexandra Leary, Christophe Marzac, MD, Jean-Baptiste Micol, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-139971
Published: 2020
Journal Articles

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Alexandre Fagnan, Frederik Otzen Bagger, Maria-Riera Piqué-Borràs, Cathy Ignacimouttou, Alexis Caulier, Cécile K. Lopez, Elie Robert, Benjamin Uzan, Véronique Gelsi-Boyer, Zakia Aid, Cécile Thirant, Ute Moll, Samantha Tauchmann, Amina Kurtovic-Kozaric, Jaroslaw Maciejewski, Christine Dierks, Orietta Spinelli, Silvia Salmoiraghi, Thomas Pabst, Kazuya Shimoda, Virginie Deleuze, Hélène Lapillonne, Connor Sweeney, Véronique De Mas, Betty Leite, Zahra Kadri, Sébastien Malinge, Stéphane de Botton, Jean-Baptiste Micol, Benjamin Kile, Catherine L. Carmichael, Ilaria Iacobucci, Charles G. Mullighan, Martin Carroll, Peter Valent, Olivier A. Bernard, Eric Delabesse, Paresh Vyas, Daniel Birnbaum, Eduardo Anguita, Loïc Garçon, Eric Soler, Juerg Schwaller, Thomas Mercher
Journal: Blood
Blood (2020) 136 (6): 698–714.
https://doi.org/10.1182/blood.2019003062
Published: 2020
Includes: Supplemental data
Journal Articles

Results of a Clinical Trial of H3B-8800, a Splicing Modulator, in Patients with Myelodysplastic Syndromes (MDS), Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML)

David P. Steensma, MD, Martin Wermke, MD, Virginia M. Klimek, MD, Peter L Greenberg, MD, Patricia Font, Rami S. Komrokji, MD, Jay Yang, MD, Andrew M. Brunner, MD, Hetty E. Carraway, MD MBA, Lionel Ades, MD PhD, Aref Al-Kali, MD, Juan Manuel Alonso Dominguez, MD PhD MSc, Ana Alonso, MD, Catherine C. Coombs, MD, H. Joachim Deeg, MD, William B. Donnellan, MD, James M. Foran, MD, Guillermo Garcia-Manero, MD, Michael B. Maris, MD, Malgorzata McMasters, MD, Jean-Baptiste Micol, MD, Jaime Perez De Oteyza, MD PhD, Felicitas Thol, MD, Eunice S. Wang, MD, Justin M. Watts, MD, Silvia Buonamici, PhD, Amy Kim, MSPh PhD, Vikram Gourineni, MS, PharmD, Alyssa J Marino, Nathalie Rioux, MSc, PhD, Joanne Schindler, MD, Sherri Smith, MS, Huilan Yao, PhD, Xiaobin Yuan, Kun Yu, PhD, Uwe Platzbecker
Journal: Blood
Blood (2019) 134 (Supplement_1): 673.
https://doi.org/10.1182/blood-2019-123854
Published: 2019
Journal Articles

Clonal Hematopoiesis in the Molecular Landscape of Therapy-Related Myeloid Neoplasms in Patients Previously Treated for Gynecologic and Breast Cancers

Sabine Khalife-Hachem, Khalil Saleh, MD, Florence Pasquier, MD PhD, Anthony Tarabay, Cyril Quivoron, Sophie Cotteret, Christophe Willekens, MD, Veronique Saada, Ines-Maria Vaz-Luis, Suzette Delaloge, Alexandra Leary, Hana Raslova, PhD, Filippo Rosselli, Olivier Caron, Iléana Antony-Debre, PhD, Eric Solary, MD PhD, Stephane de Botton, MD PhD, Christophe Marzac, MD, Jean-Baptiste Micol, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3722.
https://doi.org/10.1182/blood-2019-126872
Published: 2019
Journal Articles

CPX-351 Induces Deep Response and Suppress the Impact of Poor Prognosis Mutations ( TP53, ASXL1, RUNX1 and EVI1 ) Defined By ELN-2017 in t-AML and MRC AML: A Report from a Multicentric French Cohort

Edmond Chiche, Sarah Bertoli, MD PhD, Ramy Rahmé, MD, Jean Baptiste Micol, Florence Pasquier, MD PhD, Pierre Peterlin, Patrice Chevallier, MD, Xavier Thomas, MD PhD, Michael Loschi, MD PhD, Alexis Genthon, Olivier Legrand, MD PhD, Mohamad Mohty, MD PhD, Emmanuel Raffoux, MD, Patrick Auberger, PhD, Alexis Caulier, MD, Magalie Joris, MD, Caroline Bonmati, Gabrielle Roth Guepin, Mathieu Sauvezie, Caroline Lejeune, Arnaud Pigneux, Christian Recher, MD PhD, Lionel Ades, MD PhD, Thomas Cluzeau, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1355.
https://doi.org/10.1182/blood-2019-125623
Published: 2019
Journal Articles

Prognostic Significance of Concurrent Gene Mutations in Intensively Treated Patients with IDH1/2 Mutated AML

Matthieu Duchmann, Jean-Baptiste Micol, MD, Nicolas Duployez, PharmD, PhD, Emmanuel Raffoux, MD, Xavier Thomas, MD PhD, Jean-Pierre Marolleau, MD PhD, Thorsten Braun, MD, Lionel Ades, MD PhD, Sylvain Chantepie, MD, Emilie Lemasle, MD, Celine Berthon, MD PhD, Jean Valère Malfuson, MD, Cecile Pautas, MD, Juliette Lambert, MD, Nicolas Boissel, MD PhD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Pascal Turlure, MD, Norbert Vey, MD PhD, Arnaud Pigneux, Christian Recher, MD PhD, Christine Terré, PharmD, PhD, Claude Gardin, Raphael Itzykson, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD, Stephane De Botton
Journal: Blood
Blood (2019) 134 (Supplement_1): 1416.
https://doi.org/10.1182/blood-2019-127082
Published: 2019
Journal Articles

Oncogenic Predictors of Outcome in Older AML Patients Treated Intensively. Analysis of the ALFA-1200 Trial

Raphael Itzykson, MD PhD, Elise Fournier, Thorsten Braun, MD PhD, Céline Berthon, MD PhD, Alice Marceau-Renaut, Cecile Pautas, Olivier Nibourel, Emilie Lemasle, MD, Nicolas Duployez, PharmD, PhD, Jean-Baptiste Micol, MD PhD, Lionel Ades, MD PhD, Jean-Pierre Marolleau, MD PhD, Jean Valère Malfuson, MD, Lauris Gastaud, Emmanuel Raffoux, MD, Philippe Rousselot, MD, Xavier Thomas, MD, Sylvain Chantepie, MD, Thomas Cluzeau, MDPhD, Benjamin Papoular, Nicolas Boissel, MD PhD, Christine Terré, PharmD, PhD, Karine Celli-Lebras, CRA, Herve Dombret, MD, Claude Gardin, Claude Preudhomme
Journal: Blood
Blood (2018) 132 (Supplement 1): 993.
https://doi.org/10.1182/blood-2018-99-111144
Published: 2018
Journal Articles

ATG2B/Gskip in De Novo Acute Myeloid Leukemia (AML): High Prevalence of Germline Predisposition in French West Indies and Potential Role of Overexpression in Acquired AML

Jean Pegliasco, Barbara Panneau-Schmaltz, PhD, Jean-Edouard Martin, Samy Chraibi, Clemence Legoupil, Florence Pasquier, MD PhD, Christophe Willekens, MD, Odile Bera, Olivier Caron, Jean-Henri Bourhis, Roseline Tang, Adel Ben-Ali, Maureen Lopez, Sophie Cotteret, Veronique Saada, Nathalie Auger, Jacques Delaunay, MD, Pascale Cornillet-Lefebvre, Christian Recher, MD PhD, Stephane de Botton, MD PhD, William Vainchenker, MD PhD, Pascal Fuseau, Raouf Benabelali, Philippe Helias, Christophe Marzac, MD, Isabelle Plo, PhD, Jean-Come Meniane, MD, Christine Bellanné-Chantelot, PharmD, PhD, Jean-Baptiste Micol, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1482.
https://doi.org/10.1182/blood-2018-99-110366
Published: 2018
Journal Articles

Clonal interference of signaling mutations worsens prognosis in core-binding factor acute myeloid leukemia

Raphael Itzykson, Nicolas Duployez, Annette Fasan, Gauthier Decool, Alice Marceau-Renaut, Manja Meggendorfer, Eric Jourdan, Arnaud Petit, Hélène Lapillonne, Jean-Baptiste Micol, Pascale Cornillet-Lefebvre, Norbert Ifrah, Guy Leverger, Hervé Dombret, Nicolas Boissel, Torsten Haferlach, Claude Preudhomme
Journal: Blood
Blood (2018) 132 (2): 187–196.
https://doi.org/10.1182/blood-2018-03-837781
Published: 2018
Includes: Supplemental data
Journal Articles

The Impact of Risk-Adapted Treatment Strategy on Outcome of Patients with Acute Myeloid Leukemia Aged ≥ 60 Years after Allogeneic Stem Cell Transplantation

Riwa Sakr, MD, Sylvain Pilorge, MD, Stephane De Botton, Claude Chahine, MD, Tereza Coman, MD PhD, Marcel Adler, MD, Jean-Baptiste Micol, MD PhD, Florence Pasquier, MD PhD, Christophe Willekens, MD, Alina Danu, MD, Julien Lazarovici, MD, David Ghez, MD PhD, Eric Solary, MD, Vincent Ribbag, Jean-Henri Bourhis, Cristina Castilla-LLorente, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5544.
https://doi.org/10.1182/blood.V130.Suppl_1.5544.5544
Published: 2017
Journal Articles

Clonal Interference of Signaling Mutations Holds Prognostic Relevance in Core Binding Factor (CBF) Acute Myeloid Leukemia (AML)

Raphael Itzykson, MD PhD, Nicolas Duployez, PharmD, PhD, Annette Fasan, PhD, Alice Marceau-Renaut, PharmD, Manja Meggendorfer, PhD, Eric Jourdan, MD, Arnaud Petit, MD PhD, Hélène Lapillonne, MD PhD, Jean-Baptiste Micol, MD PhD, Pascale Cornillet-Lefebvre, Norbert Ifrah, MD, Guy Leverger, MD PhD, Herve Dombret, MD, Nicolas Boissel, MD PhD, Torsten Haferlach, MD, Claude Preudhomme, PharmD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 26.
https://doi.org/10.1182/blood.V130.Suppl_1.26.26
Published: 2017