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Dominique Penther
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Journal Articles

Randomized study of high-dose cytarabine with or without dexamethasone as post-remission therapy in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Marie-Anne Hospital, Thibaut Leguay, Martin Carre, Corentin Orvain, Caroline Bonmati, Emmanuel Raffoux, Celestine Simand, Romain Guieze, Jamilé Frayfer, Juliette Lambert, Sylvain Chantepie, Marc Bernard, Pierre Peterlin, Magda Alexis, Pascal Turlure, Cecile Pautas, Sarah Bertoli, Ludovic Gabellier, Edouard Forcade, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Pierre-Yves Dumas, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Herve Dombret, Arnaud Pigneux, Hunault-Berger Mathilde, Stephane De Botton
Journal: Blood
Blood (2025) 146 (Supplement 1): 881.
https://doi.org/10.1182/blood-2025-881
Published: 2025
Journal Articles

Impact of midostaurin in younger AML patients intensively treated with high-dose anthracycline

Free
Pierre-Yves Dumas, Mathieu Leclerc, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Thibaut Leguay, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Sylvain Chantepie, Mael Heiblig, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Delphine Lebon, Madalina Uzunov, Jean-Valère Malfuson, Thomas Cluzeau, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Eric Delabesse, Jean-François Hamel, Raphael Itzykson, Claude Preudhomme, Stephane De Botton, Nicolas Duployez, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2025) 146 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2025-1682
Published: 2025
Journal Articles

Induction chemotherapy with a single anthracycline-containing cycle in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Cecile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Martin Carre, Sylvain Chantepie, Pierre Peterlin, Maria Pilar Gallego Hernanz, Juliette Lambert, Corentin Orvain, Romain Guieze, Pascal Turlure, Celestine Simand, Emilie Lemasle, Chantal Himberlin, Caroline Bonmati, Jean Valère Malfuson, Delphine Lebon, Thomas Cluzeau, Emmanuelle Tavernier, Jean-Baptiste Micol, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Anne Huynh, Thibaut Leguay, Isabelle Luquet, Dominique Penther, Nicolas Duployez, Eric Delabesse, Claude Preudhomme, Herve Dombret, Jean-François Hamel, Arnaud Pigneux, Hunault-Berger Mathilde
Journal: Blood
Blood (2025) 146 (Supplement 1): 43.
https://doi.org/10.1182/blood-2025-43
Published: 2025
Journal Articles

Comprehensive mutational profiling and clinical outcome of adults AML with NUP98 rearrangement

Free
Ducourneau Benoit, Arnaud Pages, Stéphanie Struski, Matthieu Decamp, Emmanuel Raffoux, Céline Berthon, Laurene Fenwarth, Vincent Marmouset, Cecile Pautas, Thomas Cluzeau, Delphine Lebon, Madalina Uzunov, Patricio Pereyra, Mael Heiblig, Jean-Valère Malfuson, Laure Farnault, Pierre-Yves Dumas, Julia HIEULLE, Sarah Bertoli, Sylvain Chantepie, Nathalie Auger, Audrey Bidet, Marie Joelle Mozziconacci, Augustin Boudry, Isabelle Luquet, Laureen Chat, Romain Loyaux, Lina EL-MURR, Emmanuelle Clappier, Claude Gardin, Mathilde Hunault, Stephane De Botton, Arnaud Pigneux, Dominique Penther, Eric Delabesse, Raphael Itzykson, Claude Preudhomme, Herve Dombret, Christian Recher, Nicolas Duployez, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 7002.
https://doi.org/10.1182/blood-2025-7002
Published: 2025
Journal Articles

Real-life CD34+CD38- leukemic stem cell (LSC) flow quantification in adult AML at diagnosis independently predicts survival of intensively but not AZA-VEN treated patients: A study of prospective observational ALFA-PPP acute leukemia french association

Free
Adriana Plesa, Alexandra COELHO, Stéphanie Mathis, Veronique Saada, Isabelle Arnoux, Valerie Bardet, Florent Dumezy, Clémentine Chauvel, Jaja Zhu, Vanessa Nivaggioni, Delphine Manzoni, Iole Oster, Dominique Penther, Nicolas Duployez, Karine Celli-Lebras, Nicole Raus, Emmanuel Raffoux, Lionel Ades, Christophe Willekens, Jean-Baptiste Micol, Stephane De Botton, Laure Farnault, Sylvain Chantepie, Thomas Cluzeau, Julia HIEULLE, Céline Berthon, Ahmad Aljijakli, Claire Bories, Kevin-James Wattebled, Renaud Buffet, Raphael Itzykson, Hervé Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2025) 146 (Supplement 1): 3483.
https://doi.org/10.1182/blood-2025-3483
Published: 2025
Journal Articles

Frequency and impact of FLT3-ITD microclones in younger AML patients

Free
Nicolas Duployez, Romane Joudinaud, Augustin Boudry, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean-François Hamel, Stephane De Botton, Arnaud Pigneux, Herve Dombret, Christian Recher, Claude Preudhomme, Pierre-Yves Dumas
Journal: Blood
Blood (2025) 146 (Supplement 1): 456.
https://doi.org/10.1182/blood-2025-456
Published: 2025
Journal Articles

Real life treatments and outcomes of older patients aged more than 60 years with FLT3-mutated acute myeloid leukemia: Report from the multicentric french observational ALFA-PPP study

Free
Ramy Rahmé, Emmanuel Raffoux, Lionel Ades, Stephane De Botton, Nicolas Duployez, Alexandra COELHO, Jean-Baptiste Micol, Sylvain Chantepie, Thomas Cluzeau, Delphine Lebon, Pierre Arnautou, Mathieu Leclerc, Laure Farnault, Ollivier Legrand, Ahmad Aljijakli, Céline Berthon, Juliette Lambert, Claire Bories, Ambroise Marçais, Julia HIEULLE, Celia Salanoubat, Pascal Turlure, Kevin-James Wattebled, Benjamin Carpentier, Jamile Frayfer, Ioana Vaida, Madalina Uzunov, Reda Garidi, Luca Inchiappa, Karine Celli-Lebras, Dominique Penther, Raynier Devillier, Raphael Itzykson, Claude Preudhomme, Renaud Buffet, Herve Dombret, Thorsten Braun
Journal: Blood
Blood (2025) 146 (Supplement 1): 449.
https://doi.org/10.1182/blood-2025-449
Published: 2025
Journal Articles

Treatments and outcomes of adult patients with TP53-mutated acute myeloid leukemia (AML) in the real-life –Report of the prospective french observational ALFA-PPP study.

Free
Jean-Baptiste Micol, Raphael Itzykson, Laure Farnault, Thomas Cluzeau, Jean-Valère Malfuson, Sylvain Chantepie, Delphine Lebon, Claire Bories, Ramy Rahme, Mathieu Leclerc, Ahmad Aljijakli, Laurene Fenwarth, Alexandra COELHO, Renaud Buffet, Emmanuel Raffoux, Christophe Willekens, Marie Sebert, Stephane De Botton, Claude Preudhomme, Herve Dombret, Dominique Penther, Nicolas Duployez, Elsa Bernard
Journal: Blood
Blood (2025) 146 (Supplement 1): 6386.
https://doi.org/10.1182/blood-2025-6386
Published: 2025
Journal Articles

Clonal Dominance in Follicular Lymphoma: A Predictor of Poor Prognosis and Histological Transformation

Free
Vincent Camus, Mathieu Viennot, Victor Bobée, Pierre-Julien Viailly, Elodie Bohers, Vinciane Rainville, Marie-Delphine Lanic, Elena-Liana Veresezan, Fanny Drieux, Emilie Leveque, Pascaline Etancelin, Dominique Penther, Hervé Tilly, Alexandra Zduniak, Philippe Ruminy, Fabrice Jardin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4353.
https://doi.org/10.1182/blood-2024-200543
Published: 2024
Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Free
Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

Flow MRD Monitoring Combining Laip/Dfn and CD34+CD38- LSCs Is a Strong Predictor of Outcome in Adult AML Independently of the ELN-2022 Risk: First Results from the Multicentric Acute Leukemia French Intergroup MRD Flow Network

Free
Adriana Plesa, Stéphanie Mathis, Florent Dumezy, Anne-Catherine Lhoumeau, Veronique Saada, Isabelle Arnoux, Jennifer Osman, Nicolas Chapuis, Franck Geneviève, Mikael Roussel, Delphine Manzoni, Anne Roggy, Remi Letestu, Veronique Harrivel, Elsa Bera, Jean Feuillard, Hélène Lapillonne, Richard Veyrat-Masson, Tatiana Raskovalova, Bouchra Badaoui, Valerie Bardet, Caroline Mayeur-Rousse, Francois Vergez, Jean Philippe Vial, Valerie Goncalves Monteiro, Frédéric Feger, Dominique Penther, Isabelle Luquet, Eric Delabesse, Nicolas Duployez, Karine Celli-Lebras, Mathilde Hunault, Raphael Itzykson, Arnaud Pigneux, Christian Récher, Hervé Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2024) 144 (Supplement 1): 226.
https://doi.org/10.1182/blood-2024-205457
Published: 2024
Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Free
Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024
Journal Articles

Current Results of Intensive Therapy in Younger Adults with Acute Myeloid Leukemia (AML): The Large Randomized French Backbone Intergroup (BIG)-1 Study on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Free
Hunault-Berger Mathilde, Cécile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Tony Marchand, Marie Anne Hospital, Mael Heiblig, Sylvain Chantepie, Martin Carré, Pierre Peterlin, Emilie Lemasle, Célestine Simand, Maria Pilar Gallego Hernanz, Anne Huynh, Edouard Forcade, Raynier Devillier, Stéphanie Nguyen Quoc, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Gerard Socié, Jean-Yves Cahn, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Arnaud Pigneux, Christian Recher, Hervé Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 967.
https://doi.org/10.1182/blood-2023-179376
Published: 2023
Journal Articles

Optical Mapping, a Promising Alternative to Gold Standard Cytogenetic Approaches in Acute Lymphoblastic Leukemias: A Blind Comparison on 10 Patients

Free
Valentin Lestringant, Nicolas Duployez, PharmD, PhD, Dominique Penther, MD, Nathalie Grardel, MD, Anne Lutun, MD, Claude Preudhomme, MD PhD, Michaela West, Joyce Lee, Jean-Pierre Marolleau, MD PhD, Loïc Garçon, Yann Ferret, PharmD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-136257
Published: 2020
Journal Articles

B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) with t(5;14)(q31;q32)/ IL3-IGH Rearrangement and Eosinophilia: A Peculiar IGH BCP-ALL

Free
Benjamin Fournier, Estelle Balducci, PharmD, Nicolas Duployez, PharmD, PhD, Emmanuelle Clappier, PharmD,PhD, Wendy Cuccuini, Elodie Bottolier-Colomb, MD, Denis Caillot, MD, Helene Cave, PharmD, PhD, Aurélie Caye-Eude, PharmD, Eric Delabesse, MD PhD, Coralie Derrieux, PharmD, Nathalie Dhedin, MD, Florent Dumezy, MD, Pascaline Etancelin, PharmD, Odile Fenneteau, MD, Jamilé Frayfer, MD, Antoine Gourmel, MD, Marie Loosveld, MD PhD, Gerard Michel, MD, Nathalie Nadal, Claire-Helene Oudin, Dominique Penther, MD, Isabelle Tigaud, MD, Nathalie Grardel, MD, Marine Lafage, MD, Andre Baruchel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2572.
https://doi.org/10.1182/blood.V130.Suppl_1.2572.2572
Published: 2017
Journal Articles

Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and Non-L265P Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases

Free
Sydney Dubois, Pierre-Julien Viailly, Elodie Bohers, PhD, Philippe Bertrand, PhD, Philippe Ruminy, PhD, Vinciane Marchand, Catherine Maingonnat, Sylvain Mareschal, PhD, Jean-Michel Picquenot, MD, Dominique Penther, Jean-Philippe Jais, Bruno Tesson, Pauline Peyrouze, Martin Figeac, PhD, Fabienne Desmots, Thierry Fest, Corinne Haioun, MD PhD, Thierry Lamy, MD PhD, Christiane Copie-Bergman, Bettina Fabiani, Richard Delarue, MD, Frédéric Peyrade, Marc Andre, MD, Nicolas Ketterer, Karen Leroy, MD PhD, Gilles A. Salles, Thierry Jo Molina, MD, Hervé Tilly, MD PhD, Fabrice Jardin, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4097.
https://doi.org/10.1182/blood.V128.22.4097.4097
Published: 2016
Journal Articles

Haploinsufficiency for NR3C1 , the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

Free
Anouk Emadali, Neda Hoghoughi, Samuel Duley, Azadeh Hajmirza, Els Verhoeyen, Francois-Loic Cosset, Philippe Bertrand, Christophe Roumier, Anne Roggy, Céline Suchaud-Martin, Martine Chauvet, Sarah Bertrand, Sieme Hamaidia, Sophie Rousseaux, Véronique Josserand, Julie Charles, Isabelle Templier, Takahiro Maeda, Juliana Bruder-Costa, Laurence Chaperot, Joel Plumas, Marie-Christine Jacob, Thierry Bonnefoix, Sophie Park, Remy Gressin, Cornelis P. Tensen, Cristina Mecucci, Elizabeth Macintyre, Dominique Leroux, Elisabeth Brambilla, Florence Nguyen-Khac, Isabelle Luquet, Dominique Penther, Christian Bastard, Fabrice Jardin, Christine Lefebvre, Francine Garnache, Mary B. Callanan
Journal: Blood
Blood (2016) 127 (24): 3040–3053.
https://doi.org/10.1182/blood-2015-09-671040
Published: 2016
Includes: Supplemental data
Journal Articles

Highly Multiplexed Targeted Sequencing of Recurrent Fusion Genes in Acute Leukemia

Free
Philippe Ruminy, PhD, Nimrod Buchbinder, MD, Thomas Larson, Vinciane Marchand, Bérangère Joly, Sylvain Mareschal, Mathieu Viennot, Marie Cornic, Elodie Bohers, PhD, Philippe Bertrand, PhD, Dominique Penther, Pascaline Etancelin, Vincent Camus, Sydney Dubois, Stéphane Lepretre, MD, Emilie Lemasle, MD, Gérard Buchonnet, MD PhD, Florian Clatot, MD, Pascale Schneider, MD, Jean-Michel Picquenot, MD, jean-Pierre Vannier, MD, Christian Bastard, MD, Herve Tilly, MD PhD, Fabrice Jardin, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2335.
https://doi.org/10.1182/blood.V124.21.2335.2335
Published: 2014
Journal Articles

Value of Cytogenetic Abnormalities in Adult Patients with Philadelphia Chromosome (Ph)-Negative Acute Lymphoblastic Leukemia (ALL) Treated in the Pediatric-Inspired Trials from the Group for Research on Adult ALL (GRAALL)

Free
Marina Lafage-Pochitaloff, Laurence Baranger, Mathilde Hunault, Wendy Cuccuini, MD, Audrey Bidet, Nicole Dastugue, MD, Isabelle Tigaud, MD, Catherine Henry, Carine Gervais, MD, Dominique Penther, Christine Lefebvre, Nathalie Nadal, Francine Mugneret, Virginie Eclache, Isabelle Radford, Nathalie Gachard, Marie-Joelle Mozziconacci, Eric Delabesse, Marie C Bene, Agnès Chassevent, Kheira Beldjord, Vahid Asnafi, MDPhD, Françoise Huguet, Véronique Lhéritier, Norbert Ifrah, Hervé Dombret, MD PhD
Journal: Blood
Blood (2014) 124 (21): 492.
https://doi.org/10.1182/blood.V124.21.492.492
Published: 2014
Journal Articles

Cytogenetic Abnormalities In a Cohort of 171 Patients with Waldenström Macroglobulinemia Before Treatment: Clinical and Biological Correlations

Free
Florence Nguyen-Khac, Julie Lejeune, Elise Chapiro, Aurore Grelier, Sarah Mould, Carole Barin, Agnes Daudignon, Nathalie Gachard, Stephanie Struski, Catherine Henry, Dominique Penther, Hossein Mossafa, Joris Andrieux, Lauren Veronese, Virginie Eclache, Chrystele Bilhou-Nabera, Isabelle Luquet, Christine Terré, Laurence Baranger, Francine Mugneret, marie-Jose Gregoire, Jean Chiesa, Sylvie Ramond, Marie-Joelle Mozziconacci, MD, PhD, Evelyne Callet-Bauchu, Helene Merle-Beral, Véronique Leblond
Journal: Blood
Blood (2010) 116 (21): 801.
https://doi.org/10.1182/blood.V116.21.801.801
Published: 2010