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Journal Articles

Impact of midostaurin in younger AML patients intensively treated with high-dose anthracycline

Free
Pierre-Yves Dumas, Mathieu Leclerc, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Thibaut Leguay, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Sylvain Chantepie, Mael Heiblig, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Delphine Lebon, Madalina Uzunov, Jean-Valère Malfuson, Thomas Cluzeau, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Eric Delabesse, Jean-François Hamel, Raphael Itzykson, Claude Preudhomme, Stephane De Botton, Nicolas Duployez, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2025) 146 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2025-1682
Published: 2025
Journal Articles

Comprehensive mutational profiling and clinical outcome of adults AML with NUP98 rearrangement

Free
Ducourneau Benoit, Arnaud Pages, Stéphanie Struski, Matthieu Decamp, Emmanuel Raffoux, Céline Berthon, Laurene Fenwarth, Vincent Marmouset, Cecile Pautas, Thomas Cluzeau, Delphine Lebon, Madalina Uzunov, Patricio Pereyra, Mael Heiblig, Jean-Valère Malfuson, Laure Farnault, Pierre-Yves Dumas, Julia HIEULLE, Sarah Bertoli, Sylvain Chantepie, Nathalie Auger, Audrey Bidet, Marie Joelle Mozziconacci, Augustin Boudry, Isabelle Luquet, Laureen Chat, Romain Loyaux, Lina EL-MURR, Emmanuelle Clappier, Claude Gardin, Mathilde Hunault, Stephane De Botton, Arnaud Pigneux, Dominique Penther, Eric Delabesse, Raphael Itzykson, Claude Preudhomme, Herve Dombret, Christian Recher, Nicolas Duployez, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 7002.
https://doi.org/10.1182/blood-2025-7002
Published: 2025
Journal Articles

Retromomelo: Real-world use of momelotinib – the french experience from the FIM group

Free
Mathilde Chanut, Imane Belhadi, Emmanuel Raffoux, Juliette Soret, Geoffroy Venton, Vincent Alcazer, Lenaig Le Clech, Jean-Christophe Ianotto, Mathieu Meunier, Paul Denous Chataigner, Mathilde Hunault, Ugo Thévenet, Elsa Lestang, Antoine Bonnet, Rafael Daltro De Oliveira, Ahmad Aljijakli, Florence Sabirou, Lina Benajiba, Jean-Jacques Kiladjian
Journal: Blood
Blood (2025) 146 (Supplement 1): 7316.
https://doi.org/10.1182/blood-2025-7316
Published: 2025
Journal Articles

Frequency and impact of FLT3-ITD microclones in younger AML patients

Free
Nicolas Duployez, Romane Joudinaud, Augustin Boudry, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean-François Hamel, Stephane De Botton, Arnaud Pigneux, Herve Dombret, Christian Recher, Claude Preudhomme, Pierre-Yves Dumas
Journal: Blood
Blood (2025) 146 (Supplement 1): 456.
https://doi.org/10.1182/blood-2025-456
Published: 2025
Journal Articles

Age‐adapted chemotherapy and MRD‐oriented transplant for Ph-negative acute lymphoblastic leukemia: the GRAALL-2014 trial

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Clinical Trials & Observations
Nicolas Boissel, Sylvie Chevret, Françoise Rigal-Huguet, Thibaut TL Leguay, Mathilde Hunault, Carlos Graux, Yves Chalandon, Eric Delabesse, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Cedric Pastoret, Martine Escoffre-Barbe, Florence Pasquier, Magalie Joris, Anne Thiebaut, Anne Huynh, Nathalie Dhedin, Emilie Lemasle, Caroline Bonmati, Sebastien Maury, Gaelle Guillerm, Ana Berceanu, Urs Schanz, Thomas Cluzeau, Pascal Turlure, Philippe Rousselot, Bernard De Prijck, Nathalie Grardel, Marie-Christine Béné, Marina Lafage-Pochitaloff, Wendy Cuccuini, Norbert H Ifrah, Véronique Lheritier, Vahid Asnafi, Emmanuelle Clappier, Hervé Dombret
Journal: Blood
Blood blood.2025029611.
https://doi.org/10.1182/blood.2025029611
Published: 2025
Includes: Supplemental data
Journal Articles

Long Term Follow-up Data after Consolidation Therapy with Ponatinib in Combination with Cytarabine in Patients with FLT3 Mutated Acute Myeloid Leukemia in First Complete Remission

Free
Thibaut Leguay, Laurène Fenwarth, Thomas Cluzeau, Anne Vekoff, Etienne Lengline, Juliette Lambert, Denis Caillot, Mathilde Hunault, Jean-Valère Malfuson, Sylvain Chantepie, Emmanuelle Tavernier, Berengere Gruson, José Fernandes, Pierre Peterlin, Melody Fort, Laure Morisset, Herve Dombret, Claude Preudhomme, Arnaud Pigneux, Philippe Rousselot
Journal: Blood
Blood (2024) 144 (Supplement 1): 2905.
https://doi.org/10.1182/blood-2024-209998
Published: 2024
Journal Articles

Sequential Intensified Conditioning Regimen Allogeneic Transplantation in Younger Adult Patients with Adverse-Risk Acute Myeloid Leukemia: A Multi-Center Prospective Study from the Acute Leukemia French Intergroup on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Free
Regis Peffault de Latour, Edouard Forcade, Anne Huynh, Mathieu Leclerc, Stéphanie Nguyen Quoc, Patrice Ceballos, Jean-Baptiste Méar, Michael Loschi, Helene Labussiere-vallet, Jean-Henri Bourhis, Bruno Lioure, Ibrahim Yakoub-Agha, Jacques-Olivier Bay, Sylvie François, Claude-Éric Bulabois, Sylvain Chantepie, Marie-Thérèse Rubio, Patrice Chevallier, Anne Lise Mesnard, Delphine Lebon, Jean Valere Malfuson, Jérôme Cornillon, Etienne Daguindau, Pascal Turlure, Natacha Maillard, Alban Villate, Marie Robin, Nicole Raus, Jean-Yves Cahn, Arnaud Pigneux, Mathilde Hunault, Christian Recher, Hervé Dombret, Gerard Socie, Jean François Hamel, Raynier Devillier
Journal: Blood
Blood (2024) 144 (Supplement 1): 3483.
https://doi.org/10.1182/blood-2024-198603
Published: 2024
Journal Articles

Flow MRD Monitoring Combining Laip/Dfn and CD34+CD38- LSCs Is a Strong Predictor of Outcome in Adult AML Independently of the ELN-2022 Risk: First Results from the Multicentric Acute Leukemia French Intergroup MRD Flow Network

Free
Adriana Plesa, Stéphanie Mathis, Florent Dumezy, Anne-Catherine Lhoumeau, Veronique Saada, Isabelle Arnoux, Jennifer Osman, Nicolas Chapuis, Franck Geneviève, Mikael Roussel, Delphine Manzoni, Anne Roggy, Remi Letestu, Veronique Harrivel, Elsa Bera, Jean Feuillard, Hélène Lapillonne, Richard Veyrat-Masson, Tatiana Raskovalova, Bouchra Badaoui, Valerie Bardet, Caroline Mayeur-Rousse, Francois Vergez, Jean Philippe Vial, Valerie Goncalves Monteiro, Frédéric Feger, Dominique Penther, Isabelle Luquet, Eric Delabesse, Nicolas Duployez, Karine Celli-Lebras, Mathilde Hunault, Raphael Itzykson, Arnaud Pigneux, Christian Récher, Hervé Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2024) 144 (Supplement 1): 226.
https://doi.org/10.1182/blood-2024-205457
Published: 2024
Journal Articles

Inflammatory Biomarkers Predict Response and Survival in Chemotherapy-Ineligible and Untreated Acute Myeloid Leukemia Patients Receiving Venetoclax-Azacytidine As Front-Line Therapy

Free
Mathilde Bastien, Maxime Jullien, Nicolas Vallet, Aline Schmidt, Tony Marchand, Amandine Le Bourgeois, Alice Garnier, Sophie Vantyghem, Aude-Marie Fourmont, Corentin Orvain, Marc Bernard, Thierry Guillaume, Jean-Baptiste Méar, Mathilde Hunault, Emmanuel Gyan, Pierre Peterlin, Patrice Chevallier
Journal: Blood
Blood (2024) 144 (Supplement 1): 1531.
https://doi.org/10.1182/blood-2024-201589
Published: 2024
Journal Articles

Cyclosporine Versus Cyclosporine Plus Mycophenolate Mofetil in Reduced Intensity Allogeneic Stem Cell Transplantation for Intermediate-Risk AML: A Multi-Center Randomized Study from the Acute Leukemia French Intergroup, on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Free
Edouard Forcade, Raynier Devillier, Jean-François Hamel, Jean-Baptiste Méar, Claude-Éric Bulabois, Jean-Henri Bourhis, Sylvain Chantepie, Pascal Turlure, Patrice Chevallier, Patrice Ceballos, Bruno Lioure, Jacques-Olivier Bay, Jean Valere Malfuson, Stéphanie Nguyen-Quoc, Marianne Schwarz, Jérôme Cornillon, Michael Loschi, Mathieu Leclerc, Marie-Thérèse Rubio, Etienne Daguindau, Natacha Maillard, Amandine Charbonnier, Nathalie Contentin, Hélène Labussière-Wallet, Alban Villate, Ibrahim Yakoub-Agha, Arnaud Pigneux, Mathilde Hunault, Christian Recher, Hervé Dombret, Nicole Raus, Marie Robin, Jean-Yves Cahn, Gerard Socie, Anne Huynh, Régis Peffault De Latour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4909.
https://doi.org/10.1182/blood-2024-203964
Published: 2024
Journal Articles

Diagnosis, prognostic factors, and assessment of ALL in adults: 2024 ELN recommendations from a European expert panel

Free
Nicola Gökbuget, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan
Journal: Blood
Blood (2024) 143 (19): 1891–1902.
https://doi.org/10.1182/blood.2023020794
Published: 2024
Includes: Supplemental data
Journal Articles

Management of ALL in adults: 2024 ELN recommendations from a European expert panel

Free
Nicola Gökbuget, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan
Journal: Blood
Blood (2024) 143 (19): 1903–1930.
https://doi.org/10.1182/blood.2023023568
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Free
Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Impact of Arsenic Trioxide in the Treatment of Higher Risk Acute Promyelocytic Leukemia

Free
Audrey Da Rocha, Bruno Cassinat, Mael Heiblig, Christian Recher, Sarah Bertoli, Caroline Bonmati, Gabrielle Roth-Guepin, Anne Zilliox, Marie Laloi, Mathilde Hunault, Céline Berthon, Nicolas Duployez, Christophe Willekens, Maria Pilar Gallego Hernanz, Marlene Ochmann, Thomas Cluzeau, Fatiha Chermat, Alexis Caulier, Emmanuel Raffoux, Pierre Fenaux, Jean Pierre Marolleau, Lionel Ades, Delphine Lebon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1471.
https://doi.org/10.1182/blood-2023-174446
Published: 2023
Journal Articles

Frontline Consolidation with Nelarabine for Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia. Results of the Graall-2014/T Atriall Phase 2 Study

Free
Nicolas Boissel, Carlos Graux, Francoise Huguet, Florence Pasquier, Aurore Touzart, Thomas Cluzeau, Ludovic Lhermitte, Eric Delabesse, Patrice Chevallier, Mathilde Hunault, Cedric Pastoret, Sebastien Maury, Nathalie Grardel, Martine Escoffre Barbe, Pascal Turlure, Beat Schafer, Marie Balsat, Philippe Rousselot, Thibaut Leguay, Eric Jourdan, Delphine Pranger, Michael Gregor, Emilie Lemasle, Anne Marie Ronchetti, Ana Berceanu, Ingrid Lafon, Madalina Uzunov, Etienne Lengline, Norbert Ifrah, Yves Chalandon, Véronique Lhéritier, Vahid Asnafi, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 962.
https://doi.org/10.1182/blood-2023-177696
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Free
Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

Hyperleukocytosis Increases the Risk of Early Relapses Independently of Genetics in AML

Free
Raphaël Liévin, Nicolas Duployez, Loïc Vasseur, Juliette Lambert, Mael Heiblig, Mathilde Hunault, Claude Gardin, Stephane De Botton, Elise Fournier, Cecile Pautas, Christine Terré, Eric Delabesse, Norbert Ifrah, Arnaud Pigneux, Celli-Lebras Karine, Christian Recher, Claude Preudhomme, Herve Dombret, Raphael Itzykson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4322.
https://doi.org/10.1182/blood-2023-173614
Published: 2023
Journal Articles

Venetoclax in Combination with Intermediate Doses of Cytarabine in Consolidation Phase for Acute Myeloid Leukemia Patients in First Complete Remission; Results of the Part 1 of the Phase 1/2 Multicentric Covenidac Study

Free
Lauris Gastaud, Pierre Peterlin, Mathilde Hunault, Emmanuel Raffoux, Sarah Bertoli, Martin Carré, Cecile Pautas, Sylvain Chantepie, Juliette Lambert, Nicolas Duployez, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Vey, Arnaud Pigneux, Eric Delabesse, Claude Preudhomme, Adriana Plesa, Francois Vergez, Jean-François Hamel, Herve Dombret, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2023-173656
Published: 2023
Journal Articles

Fms-like Tyrosine Kinase 3 Ligand Kinetic Profile Is the Strongest Factor Predicting Refractoriness after Induction and Event-Free Survival in Adults with AML: A Filo Prospective Multicentric Study

Free
Pierre Peterlin, Joëlle Gaschet, Sarah Bertoli, Marc Bernard, Martin Carre, Pierre-Yves Dumas, Mathilde Hunault, Amine Belhabri, Anne Banos, Caroline Bonmati, Emmanuelle Tavernier, Gaelle Guillerm, Sarah Bonnet, Justine Decroocq, Alain Saad, Mario Ojeda-Uribe, Romain Guieze, Tony Marchand, Christian Recher, Alice Garnier, Marie-Anne Vibet, Patrice Chevallier
Journal: Blood
Blood (2023) 142 (Supplement 1): 975.
https://doi.org/10.1182/blood-2023-173518
Published: 2023
Journal Articles

Clonal Dynamics of FLT3 -ITD Positive Acute Myeloid Leukemia Patients with Relapsed/Refractory Disease Following Intensive Chemotherapy +/- Midostaurin

Free
Romane Joudinaud, Augustin Boudry, Laurène Fenwarth, Sandrine Geffroy, Mikaël Salson, Herve Dombret, Céline Berthon, Arnaud Pigneux, Delphine Lebon, Lamya Haddaoui, Raphael Itzykson, Christian Recher, Audrey Bidet, Eric Delabesse, Mathilde Hunault, Claude Preudhomme, Nicolas Duployez, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 976.
https://doi.org/10.1182/blood-2023-182018
Published: 2023