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Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Fms-like Tyrosine Kinase 3 Ligand Kinetic Profile Is the Strongest Factor Predicting Refractoriness after Induction and Event-Free Survival in Adults with AML: A Filo Prospective Multicentric Study

Pierre Peterlin, Joëlle Gaschet, Sarah Bertoli, Marc Bernard, Martin Carre, Pierre-Yves Dumas, Mathilde Hunault, Amine Belhabri, Anne Banos, Caroline Bonmati, Emmanuelle Tavernier, Gaelle Guillerm, Sarah Bonnet, Justine Decroocq, Alain Saad, Mario Ojeda-Uribe, Romain Guieze, Tony Marchand, Christian Recher, Alice Garnier, Marie-Anne Vibet, Patrice Chevallier
Journal: Blood
Blood (2023) 142 (Supplement 1): 975.
https://doi.org/10.1182/blood-2023-173518
Published: 2023
Journal Articles

Oncogenetic-Driven Targeted Therapy for Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia : A French ALL-Target Observatory Report

Aurelie Cabannes-Hamy, Lucien Courtois, Marie Balsat, Mathieu Simonin, Françoise Huguet, Martine Escoffre-Barbe, Florence Pasquier, Caroline Bonmati, Pascal Turlure, Thomas Cluzeau, Delphine Lebon, Eve Gehlkopf, Eolia Brissot, Justine Decroocq, Patrice Chevallier, Sylvain Chantepie, Victoria Cacheux, Sebastien Maury, Safia Chebrek, Thibaut Leguay, Melody Fort, Natacha Mauz, Mathlide Lamarque, Hunault-Berger Mathilde, Stefan Wickenhauser, Jamilé Frayfer, Anne Banos, Emmanuelle Tavernier, Denis Caillot, Anne Marie Ronchetti, Celine Berthon, Etienne Lengline, Véronique Lhéritier, Hervé Dombret, Ambroise Marçais, Antoine Pinton, Guillaume P Andrieu, Nicolas Boissel, Ludovic Lhermitte, Vahid Asnafi, Philippe Rousselot
Journal: Blood
Blood (2023) 142 (Supplement 1): 518.
https://doi.org/10.1182/blood-2023-179192
Published: 2023
Journal Articles

Venetoclax and Azacitidine for Molecular Relapse during First Line Intensive Chemotherapy in Patients with NPM1 Mutated or Core Binding Factor (CBF) AML. a Study from the Dataml Registry

Jules Higué, Pierre-Yves Dumas, Laetitia Largeaud, Audrey Bidet, Émilie Klein, Olivier Mansier, Lucie Rigolot, Eric Delabesse, Anne Banos, Suzanne Tavitian, Thibaut Leguay, Sarah Guenounou, Edouard Forcade, Sarah Bertoli, Arnaud Pigneux, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 2887.
https://doi.org/10.1182/blood-2023-180773
Published: 2023
Journal Articles

Dexaml-02 : A Phase II Study of Dexamethasone Added to Induction and Postremission Therapy in Older Patients with Newly Diagnosed AML. a French Innovative Leukemia Organization (FILO) Study

Christian Recher, Sarah Bertoli, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Yosr Hicheri, Omar Benbrahim, Martin Carre, Hunault-Berger Mathilde, Anne Banos, Marc Bernard, Emmanuel Gyan, Alain Saad, Safia Chebrek, Gabrielle Roth Guepin, Veronique Dorvaux, Laurence Sanhes, Maria Pilar Gallego Hernanz, Carole Exbrayat, Laure Vincent, Chantal Himberlin, Laetitia Largeaud, Eric Delabesse, Francois Vergez, Norbert Vey, Ariane C Mineur, Célestine Simand, Isabelle Luquet, Arnaud Pigneux
Journal: Blood
Blood (2022) 140 (Supplement 1): 6149–6151.
https://doi.org/10.1182/blood-2022-158665
Published: 2022
Journal Articles

Gilteritinib Activity in Refractory or Relapsed FLT3 -Mutated Acute Myeloid Leukemia Patients Previously Treated By Intensive Chemotherapy and Midostaurin: A Study from the French AML Intergroup ALFA/Filo

Pierre-Yves Dumas, Emmanuel Raffoux, Emilie Berard, Sarah Bertoli, Marie Anne Hospital, Mael Heiblig, Yohan Desbrosses, Caroline Bonmati, Cecile Pautas, Juliette Lambert, Corentin Orvain, Anne Banos, Florence Pasquier, Pierre Peterlin, Tony Marchand, Madalina Uzunov, Jamilé Frayfer, Pascal Turlure, Thomas Cluzeau, Eric Jourdan, Chantal Himberlin, Emmanuelle Tavernier, Alban Villate, Stéphanie Haiat, Marie-Lorraine Chretien, Martin Carre, Sylvain Chantepie, Iona Vaida, Mathieu Wemeau, Safia Chebrek, Gaëlle Guillerm, Romain Guieze, Houria Debarri, Eve Gehlkopf, Kamel Laribi, Ambroise Marçais, Alberto Santagostino, Marie C Bene, Ariane C Mineur, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2022) 140 (Supplement 1): 8996–8998.
https://doi.org/10.1182/blood-2022-159125
Published: 2022
Journal Articles

Epag 2015 : A Phase II Randomized Placebo-Controlled Study to Assess the Impact on Outcome of Eltrombopag Administered to Elderly Patients with Acute Myeloid Leukemia Receiving Induction Chemotherapy. a French Innovative Leukemia Organization (FILO) Study

Arnaud Pigneux, Pierre-Yves Dumas, Marc Bernard, Norbert Vey, Audrey Bidet, Ariane Mineur, Mathilde Hunault, Martin Carre, Mario Ojeda, Anne Banos, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Gabrielle Roth Guepin, Celestine Simand, Thibaut Leguay, Emmanuel Gyan, Eric Jourdan, Jean-Philippe Vial, Tony Marchand, Yosr Hicheri, Marie C Bene, Jean Francois Hamel, Christian Recher
Journal: Blood
Blood (2022) 140 (Supplement 1): 6142–6144.
https://doi.org/10.1182/blood-2022-167000
Published: 2022
Journal Articles

A Fixed-Duration Immunochemotherapy Approach Combined with Ibrutinib in CLL Produces Deep and Sustained MRD Responses: 5.5-Year Results from the Icll-07 Filo Trial

Anne-Sophie Michallet, Rémi Letestu, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Marie-Sarah Dilhuydy, Stephane Morisset, Valérie Rouille, Béatrice Mahé, Kamel Laribi, Bruno Villemagne, Emmanuelle Ferrant, Olivier Tournilhac, Alain Delmer, Christelle Portois, Lysiane Molina, Véronique Leblond, Cécile Tomowiak, Sophie de Guibert, Frederique Orsini, Anne Banos, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, Loic Ysebaert, Caroline Dartigeas, Margot Truchan, Jean-Pierre Vilque, Therese Aurran Schleinitz, Cymbalista Florence, Stéphane Leprêtre, Vincent Lévy, Florence Nguyen Khac, Pierre Feugier
Journal: Blood
Blood (2022) 140 (Supplement 1): 7013–7015.
https://doi.org/10.1182/blood-2022-157963
Published: 2022
Journal Articles

Addition of Brentuximab Vedotin to Gemcitabine in Relapsed or Refractory T-Cell Lymphoma: Final Analysis of a Lysa Multicenter, Phase II Study. "the TOTAL Trial"

Olivier Tournilhac, Solene Lecolant, Maya Hacini, Krimo Bouabdallah, Sebastien Bailly, Kamel Laribi, Thibaut Belmondo, Marie Maerevoet, Loic Ysebaert, Stéphanie Guidez, Steven Le Gouill, Christophe Bonnet, Marc Andre, Jehan Dupuis, Catherine Thieblemont, Emmanuel Bachy, Nicolas Daguindau, Franck Morschhauser, Sabine Tricot, Pierre Feugier, Anne Banos, Thierry Lamy, Adrien Chauchet, Emmanuel Gyan, Guillaume Cartron, Hassan Farhat, Vincent Camus, Bernard Drenou, Hacene Zerazhi, David Sibon, Emmanuelle Nicolas-Virelizier, Caroline Delette, Sylvia Snauwaert, Nicole Straetmans, Richard Delarue, Marie Parrens, Samuel Griolet, Philippe Gaulard, Marie-Helene Delfau-Larue, Laurence De Leval, Gandhi Laurent Damaj
Journal: Blood
Blood (2022) 140 (Supplement 1): 2302–2305.
https://doi.org/10.1182/blood-2022-165217
Published: 2022
Journal Articles

A Phase II Study of the Efficacy and Tolerance of Azacytidine (AZA) in Steroid Dependent/Refractory Systemic Autoimmune and Inflammatory Disorders (SAID) Associated with MDS or CMML (GFM- AZA-SAID -trial)

Arsène Mékinian, Lin-Pierre Zhao, Kristell Desseaux, Rose Rose, Laurent Pascal, Pierre Peterlin, Thibault Comont, Alexandre Maria, Louis Terriou, Maud d'Aveni, Marie-Pierre Gourin, Norbert Vey, Odile bayne Rouzy, Sophie Dimicoli Salazar, Anne Banos, Stefan Wickenhauser, Benoit De Renzis, Eric Durot, Shanti Ame, Laurent Voillat, Fatiha Chermat, Anne Vekhoff, Karine Lemaire, Vincent Jachiet, Sylvie Chevret, Lionel Ades, Olivier Fain, Pierre Fenaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 3697.
https://doi.org/10.1182/blood-2021-150904
Published: 2021
Journal Articles

Salvage Therapy with Brentuximab-Vedotin and Bendamustine for Patients with Relapsed/Refractory T Cell Lymphoma. a Multicenter and Retrospective Study

Krimo Bouabdallah, Raphaëlle Aubrais, Loïc Chartier, Charles Herbaux, Anne Banos, Pauline Brice, Marlene Ochmann, David Sibon, Jean Marc Schiano De Colella, Thomas Cluzeau, Kamel Laribi, Ronan Le Calloch, Mathieu Bellal, Nicolas Daguindau, Sandy Amorim, Kossi Agbetiafa, Adrien Chauchet, Marwa Hammami, Eric Durot, Christophe Bonnet, Margot Robles, Ludovic Fouillet, Fontanet Bijou, Olivier Tournilhac, Philippe Gaulard, Marie Parrens, Noel-Jean Milpied, Gandhi Laurent Damaj
Journal: Blood
Blood (2021) 138 (Supplement 1): 620.
https://doi.org/10.1182/blood-2021-150953
Published: 2021
Journal Articles

A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL

Clinical Trials & Observations
Norbert Schmitz, Lorenz Truemper, Krimo Bouabdallah, Marita Ziepert, Mathieu Leclerc, Guillaume Cartron, Arnaud Jaccard, Peter Reimer, Eva Wagner, Martin Wilhelm, Laurence Sanhes, Thierry Lamy, Laurence de Leval, Andreas Rosenwald, Muriel Roussel, Frank Kroschinsky, Walter Lindemann, Peter Dreger, Andreas Viardot, Noël Milpied, Christian Gisselbrecht, Gerald Wulf, Emmanuel Gyan, Philippe Gaulard, Jacques Olivier Bay, Bertram Glass, Viola Poeschel, Gandhi Damaj, David Sibon, Alain Delmer, Karin Bilger, Anne Banos, Mathias Haenel, Martin Dreyling, Bernd Metzner, Ulrich Keller, Friederike Braulke, Birte Friedrichs, Maike Nickelsen, Bettina Altmann, Olivier Tournilhac
Journal: Blood
Blood (2021) 137 (19): 2646–2656.
https://doi.org/10.1182/blood.2020008825
Published: 2021
Includes: Supplemental data
Journal Articles

A fixed-duration, measurable residual disease–guided approach in CLL: follow-up data from the phase 2 ICLL-07 FILO trial

Clinical Trials & Observations Brief Report
Anne-Sophie Michallet, Rémi Letestu, Magali Le Garff-Tavernier, Carmen Aanei, Michel Ticchioni, Marie-Sarah Dilhuydy, Fabien Subtil, Valerie Rouille, Beatrice Mahe, Kamel Laribi, Bruno Villemagne, Gilles Salles, Olivier Tournilhac, Alain Delmer, Christelle Portois, Brigitte Pegourie, Veronique Leblond, Cecile Tomowiak, Sophie De Guibert, Frederique Orsini Piocelle, Anne Banos, Philippe Carassou, Guillaume Cartron, Luc-Matthieu Fornecker, Loic Ysebaert, Caroline Dartigeas, Malgorzata Truchan-Graczyk, Jean-Pierre Vilque, Thérèse Aurran, Florence Cymbalista, Stéphane Lepretre, Vincent Levy, Florence Nguyen-Khac, Pierre Feugier
Journal: Blood
Blood (2021) 137 (8): 1019–1023.
https://doi.org/10.1182/blood.2020008164
Published: 2021
Includes: Supplemental data
Journal Articles

SY-1425, a Potent and Selective RARα Agonist, in Combination with Azacitidine Demonstrates a High Complete Response Rate and a Rapid Onset of Response in RARA-Positive Newly Diagnosed Unfit Acute Myeloid Leukemia

Stephane De Botton, Thomas Cluzeau, MDPhD, Carlos Enrique Vigil, MD, Rachel J. Cook, MD, Philippe Rousselot, MDPhD, David A Rizzieri, MD, Jane L. Liesveld, MD, Pierre Fenaux, MD PhD, Thorsten Braun, MD PhD, Anne Banos, MD, Michael R. Savona, MD, Don Park, MD, Michael J. Kelly, MD MPH, MS, Angela Volkert, Li Zhou, PhD, Qing Kang-Fortner, PhD, David A. Roth, MD, Eytan M. Stein, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-134600
Published: 2020
Journal Articles

Addition of Brentuximab Vedotin to Gemcitabine in Relapsed or Refractory T-Cell Lymphoma: Results of a Lysa Multicenter, Phase II Study. "the TOTAL Trial"

Olivier Tournilhac, MD PhD, Maya Hacini, MD, Kamal Bouabdallah, MD, Kamel Laribi, MD, Marie Maerevoet, MD, Loic Ysebaert, MD PhD, Stephanie Guidez, Steven Le Gouill, MD PhD, Marc André, MD, Jehan Dupuis, MD, Catherine Thieblemont, MD PhD, Emmanuel Bachy, MD PhD, Nicolas Daguindau, MD, Franck Morschhauser, MD PhD, Sabine Tricot, MD, Pierre Feugier, MD PhD, Anne Banos, MD, Thierry Lamy De La Chapelle, MD PhD, Adrien Chauchet, MD, Emmanuel Gyan, MD PhD, Guillaume Cartron, MD PhD, Hassan Farhat, MD, Vincent Camus, Bernard Drenou, MD PhD, Hacene Zerazhi, MD, David Sibon, MD PhD, Emmanuelle Nicolas-Virelizier, MD, Caroline Delette, MD, Sylvia Snauwaert, MD, Nicole Straetmans, MD, Richard Delarue, MD, Marie Parrens, MD, Céline Bossard, MD, Laurence De Leval, MD, Philippe Gaulard, MD PhD, Gandhi Laurent Damaj, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-139224
Published: 2020
Journal Articles

Comparison of a Combination of Vosaroxin (VOS) and Intermediate-Dose Cytarabine (IDAC) with Idac for the Consolidation Therapy of Younger Patients with Favorable- and Intermediate-Risk Acute Myeloid Leukemia (AML) in First Complete Remission (CR): Preliminary Results of a Randomized Phase 2 R4-VOS Study of the French ALFA-Filo AML Intergroup

Norbert Vey, MD, Corentin Orvain, MD PhD, Christian Recher, MD PhD, Arnaud Pigneux, MD PhD, Marc Bernard, MD, Anne Banos, MD, Pierre Peterlin, MD, Sylvain Chantepie, MD, Xavier Thomas, MD PhD, Cecile Pautas, MD, Claude Gardin, Emilie Lemasle, MD, Emmanuel Raffoux, MD, Romain Guieze, MD, Chantal Himberlin, MD, Clémence Loiseau, MD, Amine Belhabri, MD, Isabelle Luquet, MD, Christine Terré, PharmD, PhD, Martin Carre, MD, Claude Preudhomme, MD PhD, Eric Delabesse, MD PhD, Karine Celli-Lebras, CRA, Ariane C Mineur, CRA, Jean-Francois Brasme, MD PhD, Jean Francois Hamel, MD, Hervé Dombret, MD, Mathilde Hunault, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137032
Published: 2020
Journal Articles

Very Long Term Follow up a Phase II Study of Post-Remission Subcutaneous (SC) Azacitidine (AZA) in Patients with AML Post-MDS or Higher-Risk (HR) MDS

Amina Cherait, Thorsten Braun, MD PhD, Krimo Bouabdallah, MD, Denis Caillot, Agnès Guerci, MD PhD, Emmanuel Raffoux, MD, Jean Pierre Marolleau, Cecile Pautas, MD, Anne Banos, MD, Chantal Himberlin, MD, Anne Laure Taksin, Arnaud Pigneux, MD PhD, Xavier Thomas, MD PhD, Norbert Vey, MD, Sylvie Chevret, MDPhD, Herve Dombret, MD PhD, Fatiha Chermat, Lionel Ades, MDPhD, Claude Gardin, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-137012
Published: 2020
Journal Articles

Prospective, Multicentric Phase II Randomized Trial Comparing the Efficacy of Methotrexate or Cyclophosphamide in Large Granular Lymphocytic Leukemia: A French National Study. Report on the Interim Analysis

Thierry Lamy, PhD MD, Cedric Pastoret, MD, Roch Houot, MD PhD, Loic Ysebaert, MD PhD, Mathilde Hunault, MD PhD, Gandhi Damaj, Anne Banos, Olivier Tournilhac, Bachra Choufi, Jean-Pierre Marolleau, MD PhD, Jehan Dupuis, MD, Alain Jacques Delmer, MD PhD, Stephane Lepretre, Emmanuel Gyan, MD PhD, Pierre Feugier, MD PhD, Sophie Rigaudeau, MD, Anne Lazareth, MD, Jean Valère Malfuson, MD, Thierry Fest, Eric Bellissant
Journal: Blood
Blood (2019) 134 (Supplement_1): 1545.
https://doi.org/10.1182/blood-2019-123439
Published: 2019
Journal Articles

Maintenance of Long-Term Undetectable Minimal Residual Disease after Combination of Ibrutinib with Abbreviated Chemotherapy in the Icll-07 Filo Trial

Anne-Sophie Michallet, MD PhD, Marie-Sarah Dilhuydy, MD, Fabien Subtil, Valérie Rouille, Beatrice Mahe, MD, Kamel Laribi, MD, Bruno Villemagne, MD, Gilles A. Salles, MD PhD, Olivier Tournilhac, Alain Jacques Delmer, MD PhD, Christelle Portois, Brigitte Pegourie, MD, Veronique Leblond, MD PhD, Cecile Tomowiak, MD, Sophie de Guibert, MD, Frederique Orsini, Anne Banos, MD, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, MD PhD, Loic Ysebaert, MD PhD, Caroline Dartigeas, MD, Margot Truchan, Jean Pierre Vilque, Thérèse Aurran, MD, Florence Cymbalista, MD PhD, Stephane Lepretre, Vincent Levy, MD PhD, Florence Nguyen-Khac, MD PhD, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Remi Letestu, Pierre Feugier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3038.
https://doi.org/10.1182/blood-2019-126720
Published: 2019
Journal Articles

Aplastic Anemia in the Elderly: A Nationwide Survey on Behalf of the French Reference Center for Aplastic Anemia

Adrien Contejean, MD, Matthieu Resche-Rigon, MD PhD, Jérôme Tamburini, MD PhD, Marion Alcantara, MD, Fabrice Jardin, MD PhD, Etienne Lengline, MD, Lionel Ades, MD PhD, Didier Bouscary, MDPhD, Ambroise Marçais, MD PhD, Delphine Lebon, MD, Cécile Moluçon-Chabrot, MD PhD, Louis Terriou, MD, Fiorenza Barraco, MD, Anne Banos, MD, Lucile Bussot, Jean-Yves Cahn, MD PhD, Pierre Hirsch, MDPhD, Natacha Maillard, MD, Laurence Simon, MD, Luc Mathieu Fornecker, Gerard Socie, MD PhD, Regis Peffault De Latour, Flore Sicre De Fontbrune, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1298.
https://doi.org/10.1182/blood-2018-99-113359
Published: 2018