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Cecile Tomowiak
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Journal Articles

Efficacy of Chemo-Free Combination Therapy with BRAF Inhibitor and Rituximab in Classic Hairy Cell Leukemia: Insights from the French Experience

Luca Inchiappa, Lise Willems, Jérôme Paillassa, Charles Herbaux, Cecile Tomowiak, Anne Lok, Diane Lara, Bijou Fontanet, Urbain Tauveron-Jalenques, Antoine Ittel, Adrien Caillet, Norbert Vey, Xavier Troussard
Journal: Blood
Blood (2023) 142 (Supplement 1): 6170.
https://doi.org/10.1182/blood-2023-186971
Published: 2023
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Interim Results of MRD Kinetics in the Eradic Trial from the Filo Group

Anne-Sophie Michallet, Anne Quinquenel, Remi Letestu, Tavernier Magali, Stéphane Morisset, Therese Aurran, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos Weil, Veronique Leblond, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valerie Rouillé, Alain Jacques Delmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2023-173341
Published: 2023
Journal Articles

Combined Treatment with Ibrutinib and Anti-CD38 Monoclonal Antibody Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia with TP53 Aberrations: Results of the Filo Phase II Study IDA53

Therese Aurran-Schleinitz, Cécile Tomowiak, Damien Roos-Weil, Emmanuelle Ferrant, Béatrice Mahé, Lysiane Molina, Loic Ysebaert, Luc Mathieu Fornecker, Anne-Sophie Michallet, Vincent Levy, Romain Guieze, Alain Delmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 7030–7031.
https://doi.org/10.1182/blood-2022-163096
Published: 2022
Journal Articles

Characteristics and Outcomes of Adult Patients with T Prolymphocytic Leukemia: A Real World Study of the French Innovative Leukemia Group (FILO)

Kamel Laribi, Loic Ysebaert, Luca Inchiappa, Bruno Villemagne, Yann Guillermin, Jérôme Paillassa, Fatiha Merabet, Cécile Guénot, Alix Baugier de Materre, Charles Herbaux, Kristell Mahe, Marion Divoux, Caroline Algrin, Stephane Lepretre, Damien Roos Weil, Cécile Tomowiak, David Ghez, Stéphanie Poulain, Marion Loirat, Caroline Dartigeas, Lise Willems, Olivier Tournilhac, Marie C Bene
Journal: Blood
Blood (2022) 140 (Supplement 1): 1485–1487.
https://doi.org/10.1182/blood-2022-157399
Published: 2022
Journal Articles

A Fixed-Duration Immunochemotherapy Approach Combined with Ibrutinib in CLL Produces Deep and Sustained MRD Responses: 5.5-Year Results from the Icll-07 Filo Trial

Anne-Sophie Michallet, Rémi Letestu, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Marie-Sarah Dilhuydy, Stephane Morisset, Valérie Rouille, Béatrice Mahé, Kamel Laribi, Bruno Villemagne, Emmanuelle Ferrant, Olivier Tournilhac, Alain Delmer, Christelle Portois, Lysiane Molina, Véronique Leblond, Cécile Tomowiak, Sophie de Guibert, Frederique Orsini, Anne Banos, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, Loic Ysebaert, Caroline Dartigeas, Margot Truchan, Jean-Pierre Vilque, Therese Aurran Schleinitz, Cymbalista Florence, Stéphane Leprêtre, Vincent Lévy, Florence Nguyen Khac, Pierre Feugier
Journal: Blood
Blood (2022) 140 (Supplement 1): 7013–7015.
https://doi.org/10.1182/blood-2022-157963
Published: 2022
Journal Articles

Preliminary Results of the Filo Phase 2 Trial for Untreated Fit Patients with Intermediate Risk Chronic Lymphocytic Leukemia Comparing Ibrutinib Plus Venetoclax (IV) Versus FCR: Results of the Month 15 MRD Evaluation

Anne Quinquenel, Rémi Letestu, Magali Le Garff-Tavernier, Fabien Subtil, Therese Aurran-Schleinitz, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos-Weil, Véronique Leblond, Marie-Sarah Dilhuydy, Caroline Dartigeas, Cecile Tomowiak, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie de Guibert, Pierre Feugier, Fatiha Merabet, Stephane Lepretre, Philippe Carassou, Julie Gay, Bénédicte Hivert, Luc Mathieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valérie Rouille, Alain Delmer, Anne-Sophie Michallet
Journal: Blood
Blood (2022) 140 (Supplement 1): 7007–7009.
https://doi.org/10.1182/blood-2022-159678
Published: 2022
Journal Articles

High Frequency of CNS Involvement in Transformed Waldenström Macroglobulinemia

Eric Durot, Lukshe Kanagaratnam, Saurabh Zanwar, Elise Toussaint, Efstathios Kastritis, Shirley D'Sa, Miguel Alcoceba, Cécile Tomowiak, Bénédicte Hivert, Caroline Protin, Jithma P. Abeykoon, Josephine M.I. Vos, Anne-Sophie Michallet, Cyrielle Rodier, Jehan Dupuis, Stéphane Leprêtre, Fatiha Merabet, Xavier Roussel, Jean-Marc Zini, Caroline Regny, Aisha S Patel, Pierre Morel, Damien Roos-Weil, Steven P. Treon, Meletios A. Dimopoulos, Ramon Garcia-Sanz, Prashant Kapoor, Jorge J. Castillo, Alain Delmer
Journal: Blood
Blood (2021) 138 (Supplement 1): 2526.
https://doi.org/10.1182/blood-2021-145440
Published: 2021
Journal Articles

Safety and Efficacy of Venetoclax-Based Treatment in Elderly CLL Patients: A Retrospective Study from the Filo Group

Charlotte Doublet, Marie-Sarah Dilhuydy, Emmanuelle Ferrant, Pierre Feugier, Alexandra Fayault, Philippine Robert, Stephane Lepretre, Alain Delmer, Cécile Tomowiak, Romain Guieze, Kamel Laribi, Marguerite Vignon, Aline Clavert, Fontanet Bijou, Daniel Re, Diane Lara, Fatiha Merabet, Emmanuelle Tchernonog, Caroline Dartigeas, Anne-Sophie Michallet, Anne Quinquenel
Journal: Blood
Blood (2021) 138 (Supplement 1): 3747.
https://doi.org/10.1182/blood-2021-149640
Published: 2021
Journal Articles

Humoral Response to mRNA Vaccines BNT162b2 and mRNA-1273 COVID-19 in Chronic Lymphocytic Leukemia Patients

Cristina Bagacean, Rémi Letestu, Chadi Al Nawakil, Ségolène Brichler, Vincent Lévy, Nanthara Sritharan, Alain Delmer, Caroline Dartigeas, Véronique Leblond, Damien Roos-Weil, Marie C Béné, Aline Clavert, Driss Chaoui, Philippe Genet, Romain Guieze, Kamel Laribi, Yamina Touileb, Bernard Drenou, Lise Willems, Cécile Tomowiak, Fatiha Merabet, Christian Puppink, Hugo Legendre, Xavier Troussard, Stéphanie Malartre, Florence Cymbalista, Anne-Sophie Michallet
Journal: Blood
Blood (2021) 138 (Supplement 1): 637.
https://doi.org/10.1182/blood-2021-152515
Published: 2021
Journal Articles

Preliminary Results of the Filo Phase 2 Trial for Untreated Fit Patients with Intermediate Risk Chronic Lymphocytic Leukemia Comparing Ibrutinib Plus Venetoclax (IV) Versus FCR

Anne-Sophie Michallet, Anne Quinquenel, Remi Letestu, Magali Le Garff-Tavernier, Fabien Subtil, Mad-Helenie Elsensohn, Therese Aurran, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos-Weil, Veronique Leblond, Marie-Sarah Dilhuydy, Cécile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie de Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Leprêtre, Philippe Carassou, Julie Gay, Bénédicte Hivert, Luc Mathieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen-Khac, Valérie Rouille, Alain Delmer
Journal: Blood
Blood (2021) 138 (Supplement 1): 641.
https://doi.org/10.1182/blood-2021-145624
Published: 2021
Journal Articles

BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia

Charles Herbaux, Christoph Kornauth, Stéphanie Poulain, Stephen J. F. Chong, Mary C. Collins, Rebecca Valentin, Liam Hackett, Olivier Tournilhac, François Lemonnier, Jehan Dupuis, Adrien Daniel, Cecile Tomowiak, Kamel Laribi, Loïc Renaud, Damien Roos-Weil, Cedric Rossi, Eric Van Den Neste, Cecile Leyronnas, Fatiha Merabet, Jean Valère Malfuson, Mourad Tiab, Loïc Ysebaert, Samuel Ng, Franck Morschhauser, Philipp B. Staber, Matthew S. Davids
Journal: Blood
Blood (2021) 137 (25): 3495–3506.
https://doi.org/10.1182/blood.2020007303
Published: 2021
Includes: Supplemental data
Journal Articles

A fixed-duration, measurable residual disease–guided approach in CLL: follow-up data from the phase 2 ICLL-07 FILO trial

Clinical Trials & Observations Brief Report
Anne-Sophie Michallet, Rémi Letestu, Magali Le Garff-Tavernier, Carmen Aanei, Michel Ticchioni, Marie-Sarah Dilhuydy, Fabien Subtil, Valerie Rouille, Beatrice Mahe, Kamel Laribi, Bruno Villemagne, Gilles Salles, Olivier Tournilhac, Alain Delmer, Christelle Portois, Brigitte Pegourie, Veronique Leblond, Cecile Tomowiak, Sophie De Guibert, Frederique Orsini Piocelle, Anne Banos, Philippe Carassou, Guillaume Cartron, Luc-Matthieu Fornecker, Loic Ysebaert, Caroline Dartigeas, Malgorzata Truchan-Graczyk, Jean-Pierre Vilque, Thérèse Aurran, Florence Cymbalista, Stéphane Lepretre, Vincent Levy, Florence Nguyen-Khac, Pierre Feugier
Journal: Blood
Blood (2021) 137 (8): 1019–1023.
https://doi.org/10.1182/blood.2020008164
Published: 2021
Includes: Supplemental data
Journal Articles

Clinico-Biological, Molecular and Prognostic Features of Patients with Diffuse Large B-Cell Lymphoma-Variant of Richter Syndrome: A Multicenter Retrospective Study of the French Innovative Leukemia Organization

Charline Moulin, Francis Guillemin, MD PhD, Thomas Remen, Florian Bouclet, Hélène Augé, Anne Quinquenel, MD PhD, Caroline Dartigeas, MD, Romain Morizot, Sandra Lomazzi, Hélène Busby, MD, Sebastien Hergalant, Eugen Tausch, MD, Cécile Tomowiak, MD, Veronique Leblond, MD PhD, Catherine Thieblemont, MD PhD, Florence Cymbalista, MD PhD, Kamel Laribi, MD, Marie C Bene, PharmSci, PhD, Stephan Stilgenbauer, MD, Romain Guieze, MD, Pierre Feugier, MD PhD, Julien Broséus
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–5.
https://doi.org/10.1182/blood-2020-137101
Published: 2020
Journal Articles

Bortezomib in Combination with Dexamethasone, Rituximab and Cyclophosphamide (B-DRC) As First - Line Treatment of Waldenstrom's Macroglobulinemia: Results of a Prospectively Randomized Multicenter European Phase II Trial

Christian Buske, MD, Meletios A Dimopoulos, Alexander Grunenberg, MD, Efstathios Kastritis, MD, Cecile Tomowiak, MD, Béatrice Mahé, MD, Xavier Troussard, MD, Roman Hajek, MD PhD, Andreas Viardot, Professor Dr, Olivier Tournilhac, Therese Aurran, Stephane Lepretre, MD, Hacene Zerazhi, MD, Benedicte Hivert, MD, Veronique Leblond, MD PhD, Sophie de Guibert, MD, Lena Brandefors, Ramon Garcia-Sanz, Maria Gomes da Silva, MD, Eva Kimby, MD PhD, Jens Dreyhaupt, Rainer Muche, Pierre Morel, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26.
https://doi.org/10.1182/blood-2020-140933
Published: 2020
Journal Articles

Large-Scale Proteomics Identifies Distinct Signatures for Richter Syndrome and De Novo Diffuse Large B-Cell Lymphoma: A French Study from the Filo Group

Romain Morizot, Sebastien Hergalant, Romain Piucco, Florian Bouclet, Anne Quinquenel, MD PhD, Caroline Dartigeas, MD, Hélène Augé, Eugen Tausch, MD, Sandra Lomazzi, Hélène Busby, MD, Cécile Tomowiak, MD, Veronique Leblond, MD PhD, Catherine Thieblemont, MD PhD, Florence Cymbalista, MD PhD, Marie C Bene, PharmD,DPhil, Stephan Stilgenbauer, MD, Romain Guieze, MD, Christine Carapito, PhD, Aurore Perrot, Luc Mathieu Fornecker, MD PhD, Pierre Feugier, MD PhD, Julien Broséus
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-137061
Published: 2020
Journal Articles

Maintenance of Long-Term Undetectable Minimal Residual Disease after Combination of Ibrutinib with Abbreviated Chemotherapy in the Icll-07 Filo Trial

Anne-Sophie Michallet, MD PhD, Marie-Sarah Dilhuydy, MD, Fabien Subtil, Valérie Rouille, Beatrice Mahe, MD, Kamel Laribi, MD, Bruno Villemagne, MD, Gilles A. Salles, MD PhD, Olivier Tournilhac, Alain Jacques Delmer, MD PhD, Christelle Portois, Brigitte Pegourie, MD, Veronique Leblond, MD PhD, Cecile Tomowiak, MD, Sophie de Guibert, MD, Frederique Orsini, Anne Banos, MD, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, MD PhD, Loic Ysebaert, MD PhD, Caroline Dartigeas, MD, Margot Truchan, Jean Pierre Vilque, Thérèse Aurran, MD, Florence Cymbalista, MD PhD, Stephane Lepretre, Vincent Levy, MD PhD, Florence Nguyen-Khac, MD PhD, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Remi Letestu, Pierre Feugier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3038.
https://doi.org/10.1182/blood-2019-126720
Published: 2019
Journal Articles

Open Label Non-Randomized Phase II Study Exploring «Chemo-Free » Treatment Association with Idelalisib + Obinutuzumab in Patients with Relapsed/Refractory (R/R) Waldenstrom's Macroglobulinemia (MW), a Filo Trial: Results of the Intermediary Analysis of the Induction Phase

Cecile Tomowiak, MD, Kristell Desseaux, Stéphanie Poulain, MD PhD, Charles Herbaux, MD, Aurore Perrot, MD PhD, Beatrice Mahe, MD, Pierre Morel, MD, Olivier Tournilhac, Stephane Lepretre, MD, Thérèse Aurran, MD, Bruno Villemagne, MD, Olivier Casasnovas, MD, Delphine Nollet, Brigitte Dreyfus, MD, Sylvie Chevret, MD PhD, Veronique Leblond, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 346.
https://doi.org/10.1182/blood-2019-122826
Published: 2019
Journal Articles

Clinical and Biological Characteristics and Outcomes of Richter Transformation : A French Multicenter Study from the Filo Group

Charline Moulin, Romain Morizot, Thomas Remen, Hélène Augé, Florian Bouclet, Marion Divoux, Sandra Lomazzi, Caroline Dartigeas, MD, Anne Quinquenel, MD, Hélène Busby, MD, Cecile Tomowiak, Veronique Leblond, MD PhD, Catherine Thieblemont, MD PhD, Florence Cymbalista, MD PhD, Marie C Bene, PharmD,DPhil, Romain Guièze, MD PhD, Julien Broseus, MD PhD, Pierre Feugier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4112.
https://doi.org/10.1182/blood-2019-128053
Published: 2019
Journal Articles

French National Retrospective Cohort of Hairy-Cell Leukemias: Risk of Second Malignancies after 10 Years of Follow-up

Jérôme Paillassa, MD, Edouard Cornet, MD, Stephanie Noel, Cecile Tomowiak, Aline Schmidt, MD, Stephane Lepretre, Sandrine Vaudaux, Jehan Dupuis, MD, Alain Devidas, MD, Joly Bertrand, MD, Charlotte Petitditdier, MD, Stéphanie Haiat, Clara Mariette, MD, Catherine Thieblemont, MD PhD, Didier Decaudin, Bernard Drenou, MD, Jean Claude Eisenmann, MD, Mario Ojeda, MD, Agnès Olivrie, MD, Marie-Pierre Gourin, Olivier Lambotte, Olivier Hermine, MD PhD, Jean Michel Karsenti, MD, Pierre Feugier, MD PhD, Willy Vaillant, Jean Gutnecht, MD, Eric Lippert, MD PhD, Fabienne Huysman, MD, Kamel Ghomari, Marouane Boubaya, PhD, Vincent Levy, MD PhD, Jérémie Riou, PhD, Gandhi Damaj, MD PhD, Mathilde Hunault, MD PhD, Xavier Troussard, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1537.
https://doi.org/10.1182/blood-2019-127560
Published: 2019
Journal Articles

Characterizing the Anti-Apoptotic Dependencies of T-Cell Prolymphocytic Leukemia Identifies HDAC and JAK/STAT Pathway Inhibitors As Promising Combination Partners to Augment Bcl-2 Targeted Killing By Venetoclax

Charles Herbaux, MD MSc, Christoph Kornauth, Stéphanie Poulain, MD PhD, Olivier Tournilhac, Mary C Collins, BA, Rebecca Valentin, MD, Stephen Jun Fei Chong, PhD, Jehan Dupuis, MD, Adrien Daniel, Micha Srour, MD, Cecile Tomowiak, MD, Kamel Laribi, MD, Damien Roos-Weil, Cedric Rossi, MD PhD, Nicolas Vanlangendonck, MSc, Cecile Leyronnas, Fatiha Merabet, MD, Jean Valère Malfuson, MD, Mourad Tiab, Samuel Ng, MD PhD, Franck Morschhauser, MD, Philipp Bernhard Staber, MD PhD, Matthew S. Davids, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 807.
https://doi.org/10.1182/blood-2019-126773
Published: 2019