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Journal Articles

Isatuximab as monotherapy and combined with dexamethasone in patients with relapsed/refractory multiple myeloma

Clinical Trials & Observations
Meletios Dimopoulos, Sara Bringhen, Pekka Anttila, Marcelo Capra, Michele Cavo, Craig Cole, Cristina Gasparetto, Vania Hungria, Matthew Jenner, Vladimir Vorobyev, Eduardo Yanez Ruiz, Jian Y. Yin, Rao Saleem, Maeva Hellet, Sandrine Macé, Bruno Paiva, Ravi Vij
Journal: Blood
Blood (2021) 137 (9): 1154–1165.
https://doi.org/10.1182/blood.2020008209
Published: 2021
Includes: Supplemental data
Journal Articles

A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study

Clinical Trials & Observations
Constantine S. Tam, Stephen Opat, Shirley D'Sa, Wojciech Jurczak, Hui-Peng Lee, Gavin Cull, Roger G. Owen, Paula Marlton, Björn E. Wahlin, Ramón Garcia Sanz, Helen McCarthy, Stephen Mulligan, Alessandra Tedeschi, Jorge J. Castillo, Jaroslaw Czyz, Carlos Fernández de Larrea, David Belada, Edward Libby, Jeffrey V. Matous, Marina Motta, Tanya Siddiqi, Monica Tani, Marek Trneny, Monique C. Minnema, Christian Buske, Veronique Leblond, Judith Trotman, Wai Y. Chan, Jingjing Schneider, Sunhee Ro, Aileen Cohen, Jane Huang, Meletios Dimopoulos
Journal: Blood
Blood (2020) 136 (18): 2038–2050.
https://doi.org/10.1182/blood.2020006844
Published: 2020
Includes: Supplemental data
Journal Articles

Carfilzomib or bortezomib with melphalan-prednisone for transplant-ineligible patients with newly diagnosed multiple myeloma

Clinical Trials & Observations
Thierry Facon, Jae Hoon Lee, Philippe Moreau, Ruben Niesvizky, Meletios Dimopoulos, Roman Hajek, Ludek Pour, Artur Jurczyszyn, Lugui Qiu, Zandra Klippel, Anita Zahlten-Kumeli, Muhtarjan Osman, Bruno Paiva, Jesus San-Miguel
Journal: Blood
Blood (2019) 133 (18): 1953–1963.
https://doi.org/10.1182/blood-2018-09-874396
Published: 2019
Includes: Supplemental data
Journal Articles

Carfilzomib vs bortezomib in patients with multiple myeloma and renal failure: a subgroup analysis of ENDEAVOR

Clinical Trials & Observations
Meletios Dimopoulos, David Siegel, Darrell J. White, Ralph Boccia, Karim S. Iskander, Zhao Yang, Amy S. Kimball, Khalid Mezzi, Heinz Ludwig, Ruben Niesvizky
Journal: Blood
Blood (2019) 133 (2): 147–155.
https://doi.org/10.1182/blood-2018-06-860015
Published: 2019
Includes: Supplemental data
Journal Articles

Impact of Prior Treatment on Patients with Relapsed Multiple Myeloma Treated with Carfilzomib and Dexamethasone Vs Bortezomib and Dexamethasone in a Subgroup Analysis of the Phase 3 Endeavor Study (NCT01568866)

Philippe Moreau, Douglas Joshua, Wee-Joo Chng, Antonio Palumbo, Hartmut Goldschmidt, Roman Hájek, Thierry Facon, Heinz Ludwig, Ludek Pour, MD, Ruben Niesvizky, Albert Oriol, MD, Laura Rosiñol, Aleksandr Suvorov, Gianluca Gaidano, Tomas Pika, Katja Weisel, Vesselina Goranova-Marinova, Heidi H. Gillenwater, Nehal Mohamed, Shibao Feng, Meletios Dimopoulos
Journal: Blood
Blood (2015) 126 (23): 729.
https://doi.org/10.1182/blood.V126.23.729.729
Published: 2015
Journal Articles

Analysis of Final Data from the Multinational, Non-Interventional, Observational Emmos Study (NCT01241396) in Patients (Pts) with Multiple Myeloma (MM) in Real-World Clinical Practice

Mohamad Mohty, MD PhD, Evangelos Terpos, Maria-Victoria Mateos, Antonio Palumbo, MD, Sandra Lejniece, Meral Beksac, MD, Mohamed Amine Bekadja, Wojciech Legiec, Meletios Dimopoulos, Svetlana Stankovic, PhD, Maria Soledad Durán, Valerio De Stefano, MD, Alessandro Corso, MD, Yulia Kochkareva, Edward Laane, MD PhD, Christian Berthou, MD PhD, Hans-Juergen Salwender, MD, Zvenyslava Masliak, Valdas Pečeliūnas, Wolfgang Willenbacher, MD, João Da Silva, Vernon Louw, Damir Nemet, MD PhD, Zita Borbényi, MD PhD, Uri Abadi, MD, Robert Schou Pedersen, Peter Cernelc, Anna Potamianou, MD PhD, Catherine Couturier, Robert Olie, PhD, Caroline Feys, MSc, MBA, Florence Thoret-Bauchet, Mario Boccadoro, MD
Journal: Blood
Blood (2015) 126 (23): 3034.
https://doi.org/10.1182/blood.V126.23.3034.3034
Published: 2015
Journal Articles

Healthcare Resource Utilization Trends over Time with Continuous Lenalidomide Treatment (Tx) in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM)

Katja Weisel, MD, Dan T. Vogl, Michel Delforge, MD PhF, Kevin Song, Meletios Dimopoulos, Jamie Cavenagh, Cyrille Hulin, Philippe Rodon, Bertrand Arnulf, Robin Foá, MD, Albert Oriol, MD, Shien Guo, Mara Silvia Monzini, Jason Van Oostendorp, Annette Ervin-Haynes, Thierry Facon, MD
Journal: Blood
Blood (2014) 124 (21): 1326.
https://doi.org/10.1182/blood.V124.21.1326.1326
Published: 2014
Journal Articles

Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma

Aristeidis Chaidos, Chris P. Barnes, Gillian Cowan, Philippa C. May, Valeria Melo, Evdoxia Hatjiharissi, Maria Papaioannou, Heather Harrington, Helen Doolittle, Evangelos Terpos, Meletios Dimopoulos, Saad Abdalla, Helen Yarranton, Kikkeri Naresh, Letizia Foroni, Alistair Reid, Amin Rahemtulla, Michael Stumpf, Irene Roberts, Anastasios Karadimitris
Journal: Blood
Blood (2013) 121 (2): 318–328.
https://doi.org/10.1182/blood-2012-06-436220
Published: 2013
Includes: Supplemental data
Journal Articles

Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2

Clinical Trials & Observations
Nikhil C. Munshi, Kenneth C. Anderson, P. Leif Bergsagel, John Shaughnessy, Antonio Palumbo, Brian Durie, Rafael Fonseca, A. Keith Stewart, Jean-Luc Harousseau, Meletios Dimopoulos, Sundar Jagannath, Roman Hajek, Orhan Sezer, Robert Kyle, Pieter Sonneveld, Michele Cavo, S. Vincent Rajkumar, Jesus San Miguel, John Crowley, Hervé Avet-Loiseau, on behalf of the International Myeloma Workshop Consensus Panel 2
Journal: Blood
Blood (2011) 117 (18): 4696–4700.
https://doi.org/10.1182/blood-2010-10-300970
Published: 2011
Journal Articles

Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1

Clinical Trials & Observations
S. Vincent Rajkumar, Jean-Luc Harousseau, Brian Durie, Kenneth C. Anderson, Meletios Dimopoulos, Robert Kyle, Joan Blade, Paul Richardson, Robert Orlowski, David Siegel, Sundar Jagannath, Thierry Facon, Hervé Avet-Loiseau, Sagar Lonial, Antonio Palumbo, Jeffrey Zonder, Heinz Ludwig, David Vesole, Orhan Sezer, Nikhil C. Munshi, Jesus San Miguel, on behalf of the International Myeloma Workshop Consensus Panel 1
Journal: Blood
Blood (2011) 117 (18): 4691–4695.
https://doi.org/10.1182/blood-2010-10-299487
Published: 2011
Journal Articles

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

Clinical Trials & Observations
Meletios Dimopoulos, Robert Kyle, Jean-Paul Fermand, S. Vincent Rajkumar, Jesus San Miguel, Asher Chanan-Khan, Heinz Ludwig, Douglas Joshua, Jayesh Mehta, Morie Gertz, Hervé Avet-Loiseau, Meral Beksaç, Kenneth C. Anderson, Philippe Moreau, Seema Singhal, Hartmut Goldschmidt, Mario Boccadoro, Shaji Kumar, Sergio Giralt, Nikhil C. Munshi, Sundar Jagannath, on behalf of the International Myeloma Workshop Consensus Panel 3
Journal: Blood
Blood (2011) 117 (18): 4701–4705.
https://doi.org/10.1182/blood-2010-10-299529
Published: 2011
Journal Articles

Myeloma in patients younger than age 50 years presents with more favorable features and shows better survival: an analysis of 10 549 patients from the International Myeloma Working Group

Clinical Trials & Observations
Heinz Ludwig, Brian G. M. Durie, Vanessa Bolejack, Ingemar Turesson, Robert A. Kyle, Joan Blade, Rafael Fonseca, Meletios Dimopoulos, Kazuyuki Shimizu, Jesus San Miguel, Jan Westin, Jean-Luc Harousseau, Meral Beksac, Mario Boccadoro, Antonio Palumbo, Bart Barlogie, Chaim Shustik, Michele Cavo, Philip R. Greipp, Douglas Joshua, Michel Attal, Pieter Sonneveld, John Crowley
Journal: Blood
Blood (2008) 111 (8): 4039–4047.
https://doi.org/10.1182/blood-2007-03-081018
Published: 2008
Includes: Supplemental data
Journal Articles

Relapsed/Refractory Multiple Myeloma Patients Treated with Lenalidomide/Dexamethasone Who Achieve a Complete or near Complete Response Have Longer Overall Survival and Time to Progression Compared with Patients Achieving a Partial Response.

Jean-Luc Harousseau, Donna Weber, Meletios Dimopoulos, Marta Olesnyckyj, Zhinuan Yu, Jerome Zeldis, Robert Knight, David Siegel
Journal: Blood
Blood (2007) 110 (11): 3598.
https://doi.org/10.1182/blood.V110.11.3598.3598
Published: 2007
Journal Articles

Dexamethasone Dose Adjustments Seem To Result in Better Efficacy and Improved Tolerability in Patients with Relapsed/Refractory Multiple Myeloma Who Are Treated with Lenalidomide/Dexamethasone (MM009/010 Sub-Analysis).

Jesus F. San Miguel, Meletios Dimopoulos, Donna Weber, Marta Olesnyckyj, Zhinuan Yu, Jerome Zeldis, Robert Knight, Vincent Rajkumar
Journal: Blood
Blood (2007) 110 (11): 2712.
https://doi.org/10.1182/blood.V110.11.2712.2712
Published: 2007
Journal Articles

ECOG Performance Status Affects Efficacy, but Not Safety, of Lenalidomide/Dexamethasone in Relapsed/Refractory Multiple Myeloma (MM009/010 Sub-Analysis).

Asher A. Chanan-Khan, Meletios Dimopoulos, Donna Weber, Marta Olesnyckyj, Zhinuan Yu, Jerome Zeldis, Robert Knight, Jesus F. San Miguel
Journal: Blood
Blood (2007) 110 (11): 2721.
https://doi.org/10.1182/blood.V110.11.2721.2721
Published: 2007
Journal Articles

Lenalidomide/Dexamethasone Improves Response and Prolongs Time to Progression, Even in Patients with IgA Multiple Myeloma: A Sub-Analysis of the MM-009/010 Studies.

Robert Foa, Donna Weber, Meletios Dimopoulos, Marta Olesnyckyj, Zhinuan Yu, Jerome Zeldis, Robert Knight, Asher Alban Chanan-Khan
Journal: Blood
Blood (2007) 110 (11): 4839.
https://doi.org/10.1182/blood.V110.11.4839.4839
Published: 2007
Journal Articles

Prolonged Overall Survival with Lenalidomide Plus Dexamethasone Compared with Dexamethasone Alone in Patients with Relapsed or Refractory Multiple Myeloma.

Donna Weber, Robert Knight, Christine Chen, Andrew Spencer, Zhinuan Yu, Jerome Zeldis, Marta Olesnyckyj, Meletios Dimopoulos
Journal: Blood
Blood (2007) 110 (11): 412.
https://doi.org/10.1182/blood.V110.11.412.412
Published: 2007
Journal Articles

International Prognostic Scoring System (IPSS) for Waldenström’s Macroglobulinemia (WM).

Pierre Morel, Alain Duhamel, Paolo Gobbi, Meletios Dimopoulos, Madhav Dhodapkar, Jason McCoy, Enrique Ocio, Ramon Garcia-Sanz, Steven Treon, Veronique Leblond, Robert Kyle, Bart Barlogie, Giampaolo Merlini
Journal: Blood
Blood (2006) 108 (11): 127.
https://doi.org/10.1182/blood.V108.11.127.127
Published: 2006
Journal Articles

Lenalidomide Plus High-Dose Dexamethasone Provides Improved Overall Survival Compared to High-Dose Dexamethasone Alone for Relapsed or Refractory Multiple Myeloma (MM): Results of 2 Phase III Studies (MM-009, MM-010) and Subgroup Analysis of Patients with Impaired Renal Function.

Donna Weber, MD, Michael Wang, M.D., Christine Chen, M.D., Andrew Belch, M.D., Edward A. Stadtmauer, M.D., Ruben Niesvisky, M.D., Zhinuan Yu, Marta Olesnyckyj, Jerome Zeldis, M.D., Robert D. Knight, M.D., Meletios Dimopoulos, M.D.
Journal: Blood
Blood (2006) 108 (11): 3547.
https://doi.org/10.1182/blood.V108.11.3547.3547
Published: 2006
Journal Articles

Update on treatment recommendations from the Third International Workshop on Waldenström's Macroglobulinemia

Clinical Trials & Observations
Steven P. Treon, Morie A. Gertz, Meletios Dimopoulos, Athanasios Anagnostopoulos, Joan Blade, Andrew R. Branagan, Ramon Garcia-Sanz, Stephen Johnson, Eva Kimby, Veronique LeBlond, Jean-Paul Fermand, David G. Maloney, Giampaolo Merlini, Pierre Morel, Enrica Morra, Gwen Nichols, Enrique M. Ocio, Roger Owen, Marvin J. Stone
Journal: Blood
Blood (2006) 107 (9): 3442–3446.
https://doi.org/10.1182/blood-2005-02-0833
Published: 2006