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Journal Articles

Absence of circulating tumor cells (CTCs) defines a subtype of multiple myeloma (MM) patients (Pts) with unique clinical and biological features

Free
Esperanza Martin-Sanchez, Marta Lasa, Juan-Jose Garces, Luca Bertamini, Ioannis Kostopoulos, Mattia D'Agostino, David Žihala, Niels Weinhold, Aldo Roccaro, Jill Corre, Hector Gracia, Rosalinda Termini, Irene Manrique, Carmen Vicente, Maddalen Jimenez, Anna Sureda Balarí, Felipe Prosper, Enrique Ocio, Sebastián Garzón, Esther González García, Elena Cabezudo, Albert Oriol, Sunil Lakhwani, Albert Pérez-Montaña, Maria Casanova Espinosa, Pieter Sonneveld, Evangelos Terpos, Francesca Gay, Tomas Jelinek, Marta Larrayoz, Jose A. Martinez-Climent, Laura Rosiñol Dachs, Joan Batista Blade Creixenti, María-Victoria Mateos, Joaquin Martinez-Lopez, Juan-Jose Lahuerta Palacios, Jesus San-Miguel, Maria Teresa Cedena Romero, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2025) 146 (Supplement 1): 366.
https://doi.org/10.1182/blood-2025-366
Published: 2025
Journal Articles

Circulating tumor cells (CTCs) improve risk stratification according to the second revision of the international staging system (R2-ISS) and the ims-IMWG consensus genomic staging (CGS) in newly diagnosed multiple myeloma (NDMM): An analysis from the european CTC consortium.

Free
Mattia D'Agostino, Esperanza Martin-Sanchez, David Zihala, Ioannis Kostopoulos, Juan-Jose Garces, Noemi Puig, Giuseppe Bertuglia, Tereza Sevcikova, Tom Cupedo, Mark Van Duin, Jonathan Keats, Elena Zamagni, Philippe Moreau, Sonja Zweegman, Jill Corre, Mario Boccadoro, Meletios Dimopoulos, Roman Hajek, Bruno Paiva, Pieter Sonneveld, Annemiek Broijl, Evangelos Terpos, Tomas Jelinek, Jesus San-Miguel, Francesca Gay, Luca Bertamini
Journal: Blood
Blood (2025) 146 (Supplement 1): 364.
https://doi.org/10.1182/blood-2025-364
Published: 2025
Journal Articles

Combined assessment of circulating tumor cells (CTCs) and measurable residual disease (MRD) for dynamic risk assessment of patients (Pts) with multiple myeloma (MM)

Free
Bruno Paiva, Esperanza Martin-Sanchez, Mattia D'Agostino, Ioannis Kostopoulos, Luca Bertamini, David Žihala, Noemi Puig, Maria Teresa Cedena Romero, Hector Gracia, Pellegrino Musto, Delia Rota-Scalabrini, Angelo Belotti, Monica Galli, Elena Zamagni, Panagiotis Malandrakis, Ioannis Ntanasis-Stathopoulos, Ourania Tsitsilonis, Maria Gavriatopoulou, Sonja Zweegman, Tom Cupedo, Philippe Moreau, Jill Corre, Juan-Jose Lahuerta Palacios, Joan Batista Blade Creixenti, María-Victoria Mateos, Ondrej Venglar, Roman Hajek, Tomas Jelinek, Meletios Dimopoulos, Pieter Sonneveld, Annemiek Broijl, Marico Boccadoro, Francesca Gay, Jesus San-Miguel, Evangelos Terpos
Journal: Blood
Blood (2025) 146 (Supplement 1): 494.
https://doi.org/10.1182/blood-2025-494
Published: 2025
Journal Articles

Iberdomide maintenance after autologous stem-cell transplantation in newly diagnosed multiple myeloma: An update from the phase 2 EMN26 trial

Free
Niels W.C.J. van de Donk, Cyrille Touzeau, Evangelos Terpos, Aurore Perrot, Roberto Mina, Maaike de Ruijter, Elisabetta Antonioli, Eirini Katodrytou, Norbert Pescosta, Paulus A.F. Geerts, Cecile Sonntag Mottier, Ruth Wester, Angelo Belotti, Silvia Mangiacavalli, Massimo Offidani, Mattia D'Agostino, Mark van Duin, Paola Tacchetti, Sara Aquino, Alessandra Lombardo, Mark-David Levin, Cyrille Hulin, Mario Boccadoro, Pieter Sonneveld, Francesca Gay
Journal: Blood
Blood (2025) 146 (Supplement 1): 101.
https://doi.org/10.1182/blood-2025-101
Published: 2025
Journal Articles

Personalized prognostic model for multiple myeloma patients using continuous variables

Free
Sonia More', Alfonso Piciocchi, Samuele Confalone, Sara Bringhen, Mattia D'Agostino, Francesca Gay, Michele Cavo, Elena Zamagni, Pieter Sonneveld, Niels W.C.J. Van De Donk, Laura Corvatta, Maria Teresa Petrucci, Francesca Fazio, Mario Boccadoro, Massimo Offidani
Journal: Blood
Blood (2025) 146 (Supplement 1): 7563.
https://doi.org/10.1182/blood-2025-7563
Published: 2025
Journal Articles

Incidence and characteristics of myeloid neoplasms in patients with multiple myeloma treated with novel myeloma-directed therapies

Free
Benedetto Bruno, Aurora Martin, Chiara Caredda, Davide Stella, Giuseppe Bertuglia, Lorenzo Cani, Dicataldo Michele, Matilde Scaldaferri, Alessandra Larocca, Roberto Mina, Di Biase Federica, Mattia D'Agostino, Lanzarone Giuseppe, Francesca Gay, Eloise Beggiato, Dario Ferrero, Sara Bringhen, Luisa Giaccone
Journal: Blood
Blood (2025) 146 (Supplement 1): 3990.
https://doi.org/10.1182/blood-2025-3990
Published: 2025
Journal Articles

Designing a strong bridge to CAR-T cells with bispecifics

Free
Francesca Gay, Mattia D’Agostino
Journal: Blood
Blood (2025) 146 (17): 2012–2014.
https://doi.org/10.1182/blood.2025030525
Published: 2025
Journal Articles

Are we ready for an MRD-driven approach in multiple myeloma?

Free
Clinical Trials & Observations
Francesca Gay, Roberto Mina
Journal: Blood
Blood (2025) 146 (1): 2–4.
https://doi.org/10.1182/blood.2024028273
Published: 2025
Journal Articles

The bone marrow NK-cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy

Available to Purchase
Clinical Trials & Observations Brief Report
Charlotte L. B. M. Korst, Sabrin Tahri, Carolien Duetz, Wassilis S. C. Bruins, A. Vera de Jonge, Madelon E. de Jong, Cathelijne Fokkema, Febe Smits, Kaz Groen, Christie P. M. Verkleij, Kristine A. Frerichs, Natalie Papazian, Mark van Duin, Gregory van Beek, Remco Hoogenboezem, Thomas Baardemans, Giada Dal Collo, Elodie C. G. Stoetman, Meliha Cosovic, Inoka Twickler, Rosa Rentenaar, Merve Eken, Paola M. Homan-Weert, Elona Saraci, Mattia D’Agostino, Vincent H. J. van der Velden, Mathijs A. Sanders, Francesca Gay, Annemiek Broijl, Philippe Moreau, Pieter Sonneveld, Sonja Zweegman, Tuna Mutis, Tom Cupedo, Niels W. C. J. van de Donk
Journal: Blood
Blood (2025) 145 (25): 3007–3014.
https://doi.org/10.1182/blood.2024026455
Published: 2025
Includes: Supplemental data
Journal Articles

An International Study of 343 Newly Diagnosed MM Patients with Acute Renal Failure Due to Cast Nephropathy: Assessment of Factors Affecting Renal Response

Free
Heinz Ludwig, Meletios A. Dimopoulos, Meral Beksac, Frank Bridoux, Guldane Cengis-Seval, Luca Arcaini, Foteini Theodorakakou, Hermine Agis, Francesca Gay, Aristeidis Chaidos, Dario Roccatello, Daniele Derudas, Andrea Havasi, Julie Krainer, Silvia Mangiacavalli, Elise Michelon, Javier De La Rubia, Nattawat Klomjit, Tamer Shehab, Kenar Jhaveri, Nelson Leung, Efstathios Kastritis
Journal: Blood
Blood (2024) 144 (Supplement 1): 3328.
https://doi.org/10.1182/blood-2024-200038
Published: 2024
Journal Articles

Expanding the Eureka Study: Integrating a Comprehensive Clinical Registry with Molecular Profiling to Advance AL Amyloidosis Research

Free
Mario Nuvolone, Ute Hegenbart, Bruno Paiva, Monique C. Minnema, Enkelejda Miho, Marta Lasa, Paolo Milani, Alain van Mil, Marish I. F. Oerlemans, Jan Kruta, Ramon Lecumberri Villamediana, Alice Nevone, Luca Arcaini, Francesca Gay, Francesco Di Raimondo, Pellegrino Musto, Eloisa Riva, Mohammed Aljama, Krzysztof Jamroziak, Roberta Shcolnik Szor, Mathias Brehon, Giampaolo Merlini, Stefan Schonland, Giovanni O. Palladini
Journal: Blood
Blood (2024) 144 (Supplement 1): 1927.1.
https://doi.org/10.1182/blood-2024-200529
Published: 2024
Journal Articles

Consolidation Treatment with VRD Followed By Maintenance with Lenalidomide in Multiple Myeloma Improves Overall Survival: Long-Term Follow-up of the EMN02/HOVON95 Randomized Phase 3 Trial

Free
Pieter Sonneveld, Meletios A. Dimopoulos, Meral Beksac, Bronno van der Holt, Francesca Gay, Heinz Ludwig, Sonja Zweegman, Vladimir Maisnar, Maria Teresa Petrucci, Paolo Corradini, Francesca Patriarca, Angelo Belotti, Micol Quaresima, Mariella Grasso, Massimo Offidani, Laura Paris, Anna Marina Liberati, Markus Hansson, Heleen Visser-Wisselaar, Giulia Fumero, Renato Zambello, Paula F Ypma, Anna Pascarella, Niels Frost Andersen, Alexandra Croockewit, Mario Boccadoro, Michele Cavo
Journal: Blood
Blood (2024) 144 (Supplement 1): 674.
https://doi.org/10.1182/blood-2024-197908
Published: 2024
Journal Articles

Early Relapse in Patients with Newly-Diagnosed Multiple Myeloma: A European Myeloma Network/Harmony Alliance Analysis Including 10843 Patients

Free
Elias K. Mai, Andrea Manubens, Mattia D'Agostino, David A. Cairns, Alessandra Larocca, Juan José Lahuerta Palacios, Ruth Wester, Uta Bertsch, Anders Waage, Elena Zamagni, María-Victoria Mateos, Daniele Dall'Olio, Niels W.C.J. van de Donk, Graham Jackson, Serena Rocchi, Hans Salwender, Joan Bladé, Bronno van der Holt, Gastone Castellani, Katja C. Weisel, Francesca Gay, Sonja Zweegman, Michele Cavo, Jesus Maria Hernandez Rivas, Benedetto Bruno, Gordon Cook, Martin F Kaiser, Hartmut Goldschmidt, Mario Boccadoro, Jesús F. San-Miguel, Pieter Sonneveld
Journal: Blood
Blood (2024) 144 (Supplement 1): 898.
https://doi.org/10.1182/blood-2024-193310
Published: 2024
Journal Articles

Health-Related Quality of Life in Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Data from the Perseus Trial of Subcutaneous Daratumumab Combined with Bortezomib, Lenalidomide, and Dexamethasone (D-VRd)

Free
Pieter Sonneveld, Meletios A. Dimopoulos, Mario Boccadoro, Hang Quach, Phoebe Joy Ho, Meral Beksac, Cyrille Hulin, Elisabetta Antonioli, Xavier Leleu, Silvia Mangiacavalli, Aurore Perrot, Michele Cavo, Angelo Belotti, Annemiek Broijl, Francesca Gay, Roberto Mina, Inger S. Nijhof, Niels W.C.J. van de Donk, Eirini Katodritou, Fredrik Schjesvold, Anna Sureda Balari, Laura Rosiñol Dachs, Michel Delforge, Wilfried Roeloffzen, Christoph Driessen, Annette Vangsted, Hermann Einsele, Andrew Spencer, Roman Hajek, Artur Jurczyszyn, Sarah Lonergan, Yanfang Liu, Jianping Wang, Emilie M.J. van Brummelen, Veronique Vanquickelberghe, Anna Sitthi-Amorn, Carla J. de Boer, Robin Carson, Eva G. Katz, Katharine S. Gries, Jiaqi Song, Kai Fai Ho, Paula Rodríguez-Otero, Joan Bladé, Philippe Moreau
Journal: Blood
Blood (2024) 144 (Supplement 1): 2000.
https://doi.org/10.1182/blood-2024-201630
Published: 2024
Journal Articles

Predictors of unsustained measurable residual disease negativity in patients with multiple myeloma

Free
Clinical Trials & Observations Brief Report
Mattia D’Agostino, Giuseppe Bertuglia, Delia Rota-Scalabrini, Angelo Belotti, Sonia Morè, Paolo Corradini, Stefania Oliva, Antonio Ledda, Mariella Grasso, Vincenzo Pavone, Sonia Ronconi, Iolanda Donatella Vincelli, Stelvio Ballanti, Cristina Velluti, Claudia Cellini, Alessandro Gozzetti, Angelo D. Palmas, Barbara Gamberi, Katia Mancuso, Laura Paris, Renato Zambello, Maria Teresa Petrucci, Benedetto Bruno, Pellegrino Musto, Francesca Gay
Journal: Blood
Blood (2024) 143 (7): 592–596.
https://doi.org/10.1182/blood.2023022080
Published: 2024
Includes: Supplemental data
Journal Articles

Phase 3 Randomized Study of Daratumumab (DARA) + Bortezomib, Lenalidomide, and Dexamethasone (VRd) Versus Vrd Alone in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) Who Are Eligible for Autologous Stem Cell Transplantation (ASCT): Primary Results of the Perseus Trial

Free
Pieter Sonneveld, Meletios A. Dimopoulos, Mario Boccadoro, Hang Quach, P. Joy Ho, Meral Beksac, Cyrille Hulin, Elisabetta Antonioli, Xavier Leleu, Silvia Mangiacavalli, Aurore Perrot, Michele Cavo, Angelo Belotti, Annemiek Broijl, Francesca Gay, Roberto Mina, Inger S. Nijhof, Niels W.C.J van de Donk, Eirini Katodritou, Fredrik Schjesvold, Anna Sureda Balari, Laura Rosiñol, Michel Delforge, Wilfried Roeloffzen, Tobias Silzle, Annette Vangsted, Hermann Einsele, Andrew Spencer, Roman Hajek, Artur Jurczyszyn, Sarah Lonergan, Tahamtan Ahmadi, Yanfang Liu, Jianping Wang, Diego Vieyra, Emilie M.J. van Brummelen, Veronique Vanquickelberghe, Anna Sitthi-Amorn, Carla J. de Boer, Robin Carson, Paula Rodríguez Otero, Joan Bladé, Philippe Moreau
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-1.
https://doi.org/10.1182/blood-2023-191911
Published: 2023
Journal Articles

Impact of Daratumumab on Hematopoietic Stem Cell Mobilization with G-CSF and on-Demand Plerixafor in Newly-Diagnosed Multiple Myeloma Patients

Free
Roberto Mina, Bruno Garibaldi, Giuseppe Bertuglia, Andrea Casson, Barbara Sarina, Francesca Gay, Silvio Mercadante, Jacopo Mariotti, Mattia D'Agostino, Daniela Taurino, Stefania Oliva, Alessandra Larocca, Daniele Mannina, Chiara De Philippis, Giulia Benevolo, Tiziana Francisci, Marco Lorenzi, Benedetto Bruno, Armando Santoro, Sara Bringhen, Stefania Bramanti
Journal: Blood
Blood (2023) 142 (Supplement 1): 6633.
https://doi.org/10.1182/blood-2023-180082
Published: 2023
Journal Articles

Results of the Phase III Randomized Iskia Trial: Isatuximab-Carfilzomib-Lenalidomide-Dexamethasone Vs Carfilzomib-Lenalidomide-Dexamethasone As Pre-Transplant Induction and Post-Transplant Consolidation in Newly Diagnosed Multiple Myeloma Patients

Free
Francesca Gay, Wilfried Roeloffzen, Meletios A. Dimopoulos, Laura Rosiñol, Marjolein van der Klift, Roberto Mina, Albert Oriol Rocafiguera, Eirini Katodritou, Ka Lung Wu, Paula Rodriguez Otero, Roman Hajek, Elisabetta Antonioli, Mark van Duin, Mattia D'Agostino, Joaquin Martinez-Lopez, Elena M. van Leeuwen-Segarceanu, Paola Tacchetti, Niels W.C.J. van de Donk, Katja Weisel, Luděk Pour, Jakub Radocha, Angelo Belotti, Fredrik Schjesvold, Joan Bladé, Hermann Einsele, Pieter Sonneveld, Mario Boccadoro, Annemiek Broijl
Journal: Blood
Blood (2023) 142 (Supplement 1): 4.
https://doi.org/10.1182/blood-2023-177546
Published: 2023
Journal Articles

Lenalidomide Maintenance after VTD Induction and Autologous Stem Cell Transplantation: An Italian Real-Life Study of 558 Patients

Free
Gregorio Barila, Angela Grassi, Concetta Conticello, Roberto Mina, Chiara Marcon, Francesca Fazio, Claudio Salvatore Cartia, Martina Tinelli, Maria Livia Del Giudice, Sofia Pilerci, Angelo Belotti, Anna Pascarella, Mariantonietta Tafuri, Serena Rocchi, Nicola Sgherza, Giuseppe Mele, Edoardo Scomazzon, Massimo Gentile, Marika Porrazzo, Norbert Pescosta, Anna Furlan, Massimiliano Arangio Febbo, Cristina Clissa, Andrea Casson, Rossella Ribolla, Antonio Maroccia, Chiara Lisi, Enrica Antonia Martino, Ombretta Annibali, Gabriele Buda, Elisabetta Antonioli, Silvia Mangiacavalli, Alberto Tosetto, Pellegrino Musto, Francesca Gay, Elena Zamagni, Maria Teresa Petrucci, Francesco Di Raimondo, Francesca Patriarca, Renato Zambello
Journal: Blood
Blood (2023) 142 (Supplement 1): 1959.
https://doi.org/10.1182/blood-2023-179922
Published: 2023
Journal Articles

Treatment with Daratumumab Plus Bortezomib, Cyclophosphamide, and Dexamethasone May Result in Both Hematologic and Metabolic Complete Response to Achieve Long-Term Progression Free Survival Among Patients Presenting with Extra-Medullary Disease: A European Myeloma Network Study (EMN19)

Free
Meral Beksac, Tulin Tuglular, Francesca Gay, Roberto Mina, Eirini Katodritou, Ali Unal, Michele Cavo, Guner Hayri Ozsan, Vincent H.J. Van Der Velden, H. Berna Beverloo, Michael Vermeulen, Mark van Duin, Guldane Cengiz Seval, Omur Gokmen Sevindik, Serena Merante, Kyriaki Manousou, Pieter Sonneveld, Elena Zamagni, Evangelos Terpos
Journal: Blood
Blood (2023) 142 (Supplement 1): 1956.
https://doi.org/10.1182/blood-2023-178533
Published: 2023