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Journal Articles

MAF Translocations Are Enriched in NDMM Patients with Elevated Levels of Circulating Tumor Cells Suggesting a Genetic Basis for Aggressive Disease Course

Cathelijne Fokkema, Madelon M.E. de Jong, Sabrin Tahri, Davine Hofste Op Bruinink, Zoltan Kellermayer, Chelsea den Hollander, Michael Vermeulen, Natalie Papazian, Mark van Duin, Remco Hoogenboezem, Michiel J.W. Wevers, Vincent H.J. van der Velden, Mathijs A. Sanders, Annemiek Broijl, Pieter Sonneveld, Tom Cupedo

Blood (2022) 140 (Supplement 1): 9917–9918.

https://doi.org/10.1182/blood-2022-166162

Published: 2022

Journal Articles

Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome

Blood (2022) 139 (15): 2347–2354.

https://doi.org/10.1182/blood.2021014472

Published: 2022

Includes: Supplemental data

Journal Articles

High Levels of Circulating Tumor Cells Are Associated with Increased Bone Marrow Proliferation in Newly Diagnosed Multiple Myeloma Patients

Cathelijne Fokkema, Madelon M.E. de Jong, Sabrin Tahri, Zoltan Kellermayer, Chelsea den Hollander, Michael Vermeulen, Natalie Papazian, Mark van Duin, Michiel J.W. Wevers, Mathijs A. Sanders, Vincent H.J. van der Velden, Pieter Sonneveld, Annemiek Broyl, Tom Cupedo

Blood (2021) 138 (Supplement 1): 1566.

https://doi.org/10.1182/blood-2021-145971

Published: 2021

Journal Articles

Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML

Roger Mulet-Lazaro, Stanley van Herk, Claudia Erpelinck, Eric Bindels, Mathijs A. Sanders, Carlo Vermeulen, Ivo Renkens, Peter Valk, Ari M. Melnick, Jeroen de Ridder, Michael Rehli, Claudia Gebhard, Ruud Delwel, Bas J. Wouters

Blood (2021) 138 (2): 160–177.

https://doi.org/10.1182/blood.2020009244

Published: 2021

Includes: Supplemental data

Journal Articles

Allele-Specific Expression of GATA2 in AML with CEBPA Biallelic Mutations

Roger Mulet-Lazaro, MSc, Stanley van Herk, B.Sc., Claudia Erpelinck-Verschueren, B.Sc., Mathijs A. Sanders, PhD MSc, Eric Bindels, PhD, Peter Valk, PhD, Michael Rehli, PhD, Claudia Gebhard, PhD, Ruud Delwel, PhD, B.J. Wouters

Blood (2019) 134 (Supplement_1): 1235.

https://doi.org/10.1182/blood-2019-129766

Published: 2019

Journal Articles

Lifting the veil on germline DDX41 mutations

Mathijs A. Sanders

Blood (2019) 134 (17): 1368–1370.

https://doi.org/10.1182/blood.2019002982

Published: 2019

Journal Articles

Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations

Jonas Samuel Jutzi, Titiksha Basu, Maximilian Pellmann, Sandra Kaiser, Doris Steinemann, Mathijs A. Sanders, Adil S. A. Hinai, Annelieke Zeilemaker, Sarolta Bojtine Kovacs, Christoph Koellerer, Jenny Ostendorp, Konrad Aumann, Wei Wang, Emmanuel Raffoux, Bruno Cassinat, Lars Bullinger, Brigitte Schlegelberger, Peter J. M. Valk, Heike Luise Pahl

Blood (2019) 133 (16): 1766–1777.

https://doi.org/10.1182/blood-2018-09-875047

Published: 2019

Includes: Supplemental data

Journal Articles

Archived Bone Marrow Smears Are an Excellent Source for NGS-Based Mutation Detection in Acute Myeloid Leukemia

Adil S.A. Al Hinai, MSc, Francois G. Kavelaars, Melissa Rijken, Tim Grob, MD, Kirsten Gussinklo, Annelieke Zeilemaker, Claudia Erpelinck-Verschueren, B.Sc., Mathijs A. Sanders, PhD, Kirsten van Lom, Peter J.M. Valk, PhD

Blood (2018) 132 (Supplement 1): 2783.

https://doi.org/10.1182/blood-2018-99-118066

Published: 2018

Journal Articles

Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage

Ayala Tovy, PhD, Hyun Jung Park, PhD, Jaime M. Reyes, BS, Anna Guzman, Rachel E. Rau, MD, Aaron Jeffries, PhD, Mill Jonnathan, PhD, Emma Baple, PhD, Andrew Crosby, MD, Mia Petljak, Henry Lee-Six, PhD, Heng Wang, MD PhD, Xin Baozhong, MD PhD, Mathijs A. Sanders, PhD, Peter J. Campbell, PhD, Michael Stratton, Wei Li, Margaret Goodell, PhD

Blood (2018) 132 (Supplement 1): 173.

https://doi.org/10.1182/blood-2018-173

Published: 2018

Journal Articles

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Blood (2018) 132 (14): 1526–1534.

https://doi.org/10.1182/blood-2018-05-852566

Published: 2018

Includes: Supplemental data

Journal Articles

Prospective Molecular MRD Detection By NGS: A Powerful Independent Predictor for Relapse and Survival in Adults with Newly Diagnosed AML

Blood (2017) 130 (Supplement 1): LBA-5.

https://doi.org/10.1182/blood.V130.Suppl_1.LBA-5.LBA-5

Published: 2017

Journal Articles

C-Terminal BRE Overexpression in 11q23-Rearranged and t(8;16) Acute Myeloid Leukemia Is Caused By Intragenic Transcription Initiation

Blood (2017) 130 (Supplement 1): 3810.

https://doi.org/10.1182/blood.V130.Suppl_1.3810.3810

Published: 2017

Journal Articles

Extensive RAG-Mediated Rearrangements and Mutations in BCR-ABL1 and BCR - ABL1 -like Adult Acute Lymphoblastic Leukemia

Mathijs A. Sanders, PhD, Anikó Szabó, MD, Carla Exalto, Remco Hoogenboezem, Annelieke Zeilemaker, Jasper E. Koenders, Peter van Geel, Anita Schelen, H. Berna Beverloo, PhD, Jan J. Cornelissen, MD PhD, Anita W. Rijneveld, MD PhD, Peter J.M. Valk, PhD

Blood (2016) 128 (22): 4067.

https://doi.org/10.1182/blood.V128.22.4067.4067

Published: 2016

Journal Articles

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Blood (2016) 128 (22): 428.

https://doi.org/10.1182/blood.V128.22.428.428

Published: 2016

Journal Articles

DNMT3A Mutations Enhance CpG Mutagenesis through Deregulation of the Active DNA Demethylation Pathway

Mathijs A. Sanders, PhD, Annelieke Zeilemaker, Adil al Hinai, Remco Hoogenboezem, François G. Kavelaars, BSc, Melissa Rijken, Eric M.J. Bindels, PhD, Bob Löwenberg, MD PhD, Peter J.M. Valk, PhD

Blood (2016) 128 (22): 1076.

https://doi.org/10.1182/blood.V128.22.1076.1076

Published: 2016

Journal Articles

Changes of the Mutational Landscape in Relapsed Acute Myeloid Leukemia

Blood (2016) 128 (22): 599.

https://doi.org/10.1182/blood.V128.22.599.599

Published: 2016

Journal Articles

Multiple Myeloma with a Deletion of Chromosome 17p: TP53 Mutations Are Highly Prevalent and Negatively Affect Prognosis

Blood (2016) 128 (22): 3271.

https://doi.org/10.1182/blood.V128.22.3271.3271

Published: 2016

Journal Articles

An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Blood (2016) 127 (24): 2991–3003.

https://doi.org/10.1182/blood-2016-01-695759

Published: 2016

Includes: Supplemental data

Journal Articles

Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia

Blood (2015) 126 (23): 306.

https://doi.org/10.1182/blood.V126.23.306.306

Published: 2015

Journal Articles

M3P Sequencing Panel Identifies TP53 Mutational Status As a Prognostic Factor in Chemotherapy-Naive Multiple Myeloma

Davine Hofste op Bruinink, MD MSc, K. Martin Kortüm, MD, Mark van Duin, PhD, Mathijs A. Sanders, PhD, Remco Hoogenboezem, MSc, Michael Vermeulen, BSc, Laura Bruins, Jonathan Ahmann, Annemiek Broijl, MD PhD, Sonja Zweegman, MD PhD, Esteban Braggio, PhD, Bronno van der Holt, PhD, A. Keith Stewart, MD PhD, Pieter Sonneveld, MD PhD

Blood (2015) 126 (23): 2984.

https://doi.org/10.1182/blood.V126.23.2984.2984

Published: 2015

NARROW

MAF Translocations Are Enriched in NDMM Patients with Elevated Levels of Circulating Tumor Cells Suggesting a Genetic Basis for Aggressive Disease Course

Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome

High Levels of Circulating Tumor Cells Are Associated with Increased Bone Marrow Proliferation in Newly Diagnosed Multiple Myeloma Patients

Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML

Allele-Specific Expression of GATA2 in AML with CEBPA Biallelic Mutations

Lifting the veil on germline DDX41 mutations

Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations

Archived Bone Marrow Smears Are an Excellent Source for NGS-Based Mutation Detection in Acute Myeloid Leukemia

Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Prospective Molecular MRD Detection By NGS: A Powerful Independent Predictor for Relapse and Survival in Adults with Newly Diagnosed AML

C-Terminal BRE Overexpression in 11q23-Rearranged and t(8;16) Acute Myeloid Leukemia Is Caused By Intragenic Transcription Initiation

Extensive RAG-Mediated Rearrangements and Mutations in BCR-ABL1 and BCR - ABL1 -like Adult Acute Lymphoblastic Leukemia

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

DNMT3A Mutations Enhance CpG Mutagenesis through Deregulation of the Active DNA Demethylation Pathway

Changes of the Mutational Landscape in Relapsed Acute Myeloid Leukemia

Multiple Myeloma with a Deletion of Chromosome 17p: TP53 Mutations Are Highly Prevalent and Negatively Affect Prognosis

An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia

M3P Sequencing Panel Identifies TP53 Mutational Status As a Prognostic Factor in Chemotherapy-Naive Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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