1-20 of 43
Warren S. Alexander
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Iron homeostasis governs erythroid phenotype in polycythemia vera

Cavan Bennett, Victoria E. Jackson, Anne Pettikiriarachchi, Thomas Hayman, Ute Schaeper, Gemma Moir-Meyer, Katherine Fielding, Ricardo Ataide, Danielle Clucas, Andrew Baldi, Alexandra L. Garnham, Connie S. N. Li-Wai-Suen, Stephen J. Loughran, E. Joanna Baxter, Anthony R. Green, Warren S. Alexander, Melanie Bahlo, Kate Burbury, Ashley P. Ng, Sant-Rayn Pasricha
Journal: Blood
Blood (2023) 141 (26): 3199–3214.
https://doi.org/10.1182/blood.2022016779
Published: 2023
Includes: Supplemental data
Journal Articles

The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal

Yuqing Yang, Andrew J. Kueh, Zoe L. Grant, Waruni Abeysekera, Alexandra L. Garnham, Stephen Wilcox, Craig D. Hyland, Ladina Di Rago, Don Metcalf, Warren S. Alexander, Leigh Coultas, Gordon K. Smyth, Anne K. Voss, Tim Thomas
Journal: Blood
Blood (2022) 139 (6): 845–858.
https://doi.org/10.1182/blood.2021013954
Published: 2022
Includes: Supplemental data
Journal Articles

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

Helen M. McRae, Alexandra L. Garnham, Yifang Hu, Matthew T. Witkowski, Mark A. Corbett, Mathew P. Dixon, Rose E. May, Bilal N. Sheikh, William Chiang, Andrew J. Kueh, Tan A. Nguyen, Kevin Man, Renee Gloury, Brandon J. Aubrey, Antonia Policheni, Ladina Di Rago, Warren S. Alexander, Daniel H. D. Gray, Andreas Strasser, Edwin D. Hawkins, Stephen Wilcox, Jozef Gécz, Axel Kallies, Matthew P. McCormack, Gordon K. Smyth, Anne K. Voss, Tim Thomas
Journal: Blood
Blood (2019) 133 (16): 1729–1741.
https://doi.org/10.1182/blood-2018-07-860726
Published: 2019
Includes: Supplemental data
Journal Articles

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Mathijs A. Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E. Miller, Adil S. al Hinai, Ashish Bajel, Bram Luiken, Melissa Rijken, Tamara Mclennan, Remco M. Hoogenboezem, François G. Kavelaars, Stefan Fröhling, Marnie E. Blewitt, Eric M. Bindels, Warren S. Alexander, Bob Löwenberg, Andrew W. Roberts, Peter J. M. Valk, Ian J. Majewski
Journal: Blood
Blood (2018) 132 (14): 1526–1534.
https://doi.org/10.1182/blood-2018-05-852566
Published: 2018
Includes: Supplemental data
Journal Articles

Feedback Regulation of STAT5 Is Critical to Balance MYC and BCL6-Dependent Transcriptional Programs That Regulate Cell Size and Glucose Metabolism

Zhengshan Chen, MD PhD, Huimin Geng, PhD, Lars Klemm, BSc, MSc, Lai N Chan, PhD, Brass Daniel, PhD, Warren S. Alexander, PhD, Cheryl L. Willman, MD, Markus Müschen, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4069.
https://doi.org/10.1182/blood.V128.22.4069.4069
Published: 2016
Journal Articles

Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

Kira Behrens, Ioanna Triviai, Maike Schwieger, Nilgün Tekin, Malik Alawi, Michael Spohn, Daniela Indenbirken, Marion Ziegler, Ursula Müller, Warren S. Alexander, Carol Stocking
Journal: Blood
Blood (2016) 127 (26): 3369–3381.
https://doi.org/10.1182/blood-2015-09-668129
Published: 2016
Includes: Supplemental data
Journal Articles

Regulation of Platelet Lifespan in the Presence and Absence of TPO Signaling

Marion Lebois, Mark R. Dowling, Philip D. Hodgkin, Benjamin T. Kile, Warren S. Alexander, Emma C. Josefsson
Journal: Blood
Blood (2015) 126 (23): 11.
https://doi.org/10.1182/blood.V126.23.11.11
Published: 2015
Journal Articles

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

Kathryn S. Potts, Tobias J. Sargeant, Caleb A. Dawson, Emma C. Josefsson, Douglas J. Hilton, Warren S. Alexander, Samir Taoudi
Journal: Blood
Blood (2015) 126 (6): 807–816.
https://doi.org/10.1182/blood-2014-12-616607
Published: 2015
Includes: Supplemental data
Journal Articles

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

Stanley C. W. Lee, Sarah Miller, Craig Hyland, Maria Kauppi, Marion Lebois, Ladina Di Rago, Donald Metcalf, Sarah A. Kinkel, Emma C. Josefsson, Marnie E. Blewitt, Ian J. Majewski, Warren S. Alexander
Journal: Blood
Blood (2015) 126 (2): 167–175.
https://doi.org/10.1182/blood-2014-12-615898
Published: 2015
Includes: Supplemental data
Journal Articles

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2

Sarah A. Kinkel, Roman Galeev, Christoffer Flensburg, Andrew Keniry, Kelsey Breslin, Omer Gilan, Stanley Lee, Joy Liu, Kelan Chen, Linden J. Gearing, Darcy L. Moore, Warren S. Alexander, Mark Dawson, Ian J. Majewski, Alicia Oshlack, Jonas Larsson, Marnie E. Blewitt
Journal: Blood
Blood (2015) 125 (12): 1890–1900.
https://doi.org/10.1182/blood-2014-10-603969
Published: 2015
Includes: Supplemental data
Journal Articles

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

Bilal N. Sheikh, Stanley C. W. Lee, Farrah El-Saafin, Hannah K. Vanyai, Yifang Hu, Swee Heng Milon Pang, Stephanie Grabow, Andreas Strasser, Stephen L. Nutt, Warren S. Alexander, Gordon K. Smyth, Anne K. Voss, Tim Thomas
Journal: Blood
Blood (2015) 125 (12): 1910–1921.
https://doi.org/10.1182/blood-2014-08-594655
Published: 2015
Includes: Supplemental data
Journal Articles

A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis

Jacob T. Jackson, Chayanica Nasa, Wei Shi, Nicholas D. Huntington, Clifford W. Bogue, Warren S. Alexander, Matthew P. McCormack
Journal: Blood
Blood (2015) 125 (5): 803–814.
https://doi.org/10.1182/blood-2014-06-579813
Published: 2015
Includes: Supplemental data
Journal Articles

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

Shojaee Seyedmehdi, PhD, Zhengshan Chen, MD PhD, Maike Buchner, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Hilde Schjerven, PhD, Lai N Chan, PhD, Phillip Koeffler, MD, Cheryl L. Willman, MD, Stephen Hunger, MD, Sinisa Dovat, MD,PhD, Elisabeth Paietta, PhD, Wolf-Karsten Hofmann, Ari M Melnick, MD, Warren S. Alexander, Steven M. Kornblau, MD, Markus Muschen, MDPhD
Journal: Blood
Blood (2014) 124 (21): 787.
https://doi.org/10.1182/blood.V124.21.787.787
Published: 2014
Journal Articles

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Brief Report
Kathryn S. Potts, Tobias J. Sargeant, John F. Markham, Wei Shi, Christine Biben, Emma C. Josefsson, Lachlan W. Whitehead, Kelly L. Rogers, Anna Liakhovitskaia, Gordon K. Smyth, Benjamin T. Kile, Alexander Medvinsky, Warren S. Alexander, Douglas J. Hilton, Samir Taoudi
Journal: Blood
Blood (2014) 124 (17): 2725–2729.
https://doi.org/10.1182/blood-2014-02-559468
Published: 2014
Includes: Supplemental data
Journal Articles

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Diwakar R. Pattabiraman, Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne, Ann Trezise, Jianmin Ding, Sean M. Grimmond, Peter Papathanasiou, Warren S. Alexander, Andrew C. Perkins, Jean-Pierre Levesque, Ingrid G. Winkler, Thomas J. Gonda
Journal: Blood
Blood (2014) 123 (17): 2682–2690.
https://doi.org/10.1182/blood-2012-02-413187
Published: 2014
Includes: Supplemental data
Journal Articles

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

W. Wei-Lynn Wong, James E. Vince, Najoua Lalaoui, Kate E. Lawlor, Diep Chau, Aleksandra Bankovacki, Holly Anderton, Donald Metcalf, Lorraine O’Reilly, Philipp J. Jost, James M. Murphy, Warren S. Alexander, Andreas Strasser, David L. Vaux, John Silke
Journal: Blood
Blood (2014) 123 (16): 2562–2572.
https://doi.org/10.1182/blood-2013-06-510743
Published: 2014
Includes: Supplemental data
Journal Articles

Polycomb repressive complex 2 (PRC2) suppresses Eμ- myc lymphoma

Stanley C. W. Lee, Belinda Phipson, Craig D. Hyland, Huei San Leong, Rhys S. Allan, Aaron Lun, Douglas J. Hilton, Stephen L. Nutt, Marnie E. Blewitt, Gordon K. Smyth, Warren S. Alexander, Ian J. Majewski
Journal: Blood
Blood (2013) 122 (15): 2654–2663.
https://doi.org/10.1182/blood-2013-02-484055
Published: 2013
Includes: Supplemental data
Journal Articles

Suppressor of Cytokine Signaling (SOCS) Molecules Are Critical to Balance Oncogenic Signaling Strength in Ph + ALL.

Zhengshan Chen, MD, PhD, Huimin Geng, PhD, Lars Klemm, Maike Buchner, PhD, Kaveh Hemati, BS, Seyedmehdi Shojaee, M.Sc., Warren S. Alexander, William L. Carroll, MD, Cheryl L Willman, MD, Markus Muschen, MD
Journal: Blood
Blood (2012) 120 (21): 2563.
https://doi.org/10.1182/blood.V120.21.2563.2563
Published: 2012
Journal Articles

Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia

Catherine L Carmichael, PhD, Donald Metcalf, Katya J. Henley, Elizabeth A Kruse, PhD, Ladina Di Rago, Sandra Mifsud, Jian Zhong Tang, PhD, Warren S. Alexander, Benjamin T. Kile
Journal: Blood
Blood (2012) 120 (21): 1283.
https://doi.org/10.1182/blood.V120.21.1283.1283
Published: 2012
Journal Articles

Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells

Seth L. Masters, Mordechay Gerlic, Donald Metcalf, Simon P. Preston, Marc Pellegrini, Joanne A. O'Donnell, Kate McArthur, Tracey M. Baldwin, Stephane Chevrier, Cameron J. Nowell, Louise H. Cengia, Katya J. Henley, Janelle E. Collinge, Daniel L. Kastner, Lionel Feigenbaum, Douglas J. Hilton, Warren S. Alexander, Ben A. Croker, Benjamin T. Kile
Journal: Blood
Blood (2012) 120 (21): 1213.
https://doi.org/10.1182/blood.V120.21.1213.1213
Published: 2012