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Journal Articles

Longitudinal Assessment of Transfusion Intensity in Patients with JAK Inhibitor-Naive or -Experienced Myelofibrosis Treated with Momelotinib in the Phase 3 Simplify-1 and Momentum Trials

Ruben A. Mesa, Andrew C. Perkins, Yeow Tee Goh, Maria Laura Fox, Donal P McLornan, Jeanne Palmer, Lynda Foltz, Alessandro Maria Vannucchi, Steffen Koschmieder, Francesco Passamonti, Sung-Eun Lee, Jun Kawashima, Bryan Strouse, Francisco Gonzalez Carreras, Stephen T. Oh

Blood (2023) 142 (Supplement 1): 3182.

https://doi.org/10.1182/blood-2023-177774

Published: 2023

Journal Articles

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Simranpreet Kaur, Liza J. Raggatt, Susan M. Millard, Andy C. Wu, Lena Batoon, Rebecca N. Jacobsen, Ingrid G. Winkler, Kelli P. MacDonald, Andrew C. Perkins, David A. Hume, Jean-Pierre Levesque, Allison R. Pettit

Blood (2018) 132 (7): 735–749.

https://doi.org/10.1182/blood-2018-01-829663

Published: 2018

Includes: Supplemental data

Journal Articles

A Potential Role for Genes within the mTORC1 Pathway in the Regulation of Embryonic Globin Expression Revealed By ChIP-Seq, RNA-Seq and eQTL Mapping in the Nan Anemia Mouse Model

Danitza M. Nebor, PhD, Joel H. Graber, PhD, Kevin R. Gillinder, PhD, Melissa D. Ilsley, BSc, Raymond F. Robledo, PhD, Steven L. Ciciotte, MS, Vivek Philip, PhD, James J. Bieker, PhD, Andrew C Perkins, PhD, Luanne L. Peters, PhD

Blood (2017) 130 (Supplement 1): 2203.

https://doi.org/10.1182/blood.V130.Suppl_1.2203.2203

Published: 2017

Journal Articles

JAK1 Somatic Mutation in Myeloproliferative Neoplasm

Suzanne O Arulogun, MBBS, Hock Choong Lai, MBBS, Debra Taylor, BS, Paula Ambrosoli, Graham Magor, Ian Michael Irving, MBBS, FRACP, FRCPA, Tee Beng Keng, MD, Andrew C Perkins, PhD

Blood (2017) 130 (Supplement 1): 5269.

https://doi.org/10.1182/blood.V130.Suppl_1.5269.5269

Published: 2017

Journal Articles

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Melissa Ilsley, BSc, Kevin R. Gillinder, PhD, Graham Magor, MB BS (Hons), Merlin Crossley, DPhil, Andrew C Perkins, PhD

Blood (2016) 128 (22): 1036.

https://doi.org/10.1182/blood.V128.22.1036.1036

Published: 2016

Journal Articles

Mutations in the Second Linker of KLF1 Cause Congenital Non-Spherocytic Hemolytic Anemia Due to Global Reduction of In Vivo DNA-Binding Affinity

Stephen Huang, B Sc (Hons), Kevin R. Gillinder, PhD, Annabel Sorolla, PhD, Emma Whitelaw, BSc PhD, Andrew C Perkins, PhD

Blood (2016) 128 (22): 1246.

https://doi.org/10.1182/blood.V128.22.1246.1246

Published: 2016

Journal Articles

Direct Targets of Epo Receptor-JAK2-pSTAT5 Signalling in Erythropoiesis

Kevin R. Gillinder, PhD, Hugh Tuckey, BSc (Hons), Charles Bell, BSc, Stephen Huang, B Sc (Hons), Melissa Ilsley, BSc, Graham Magor, MB BS (Hons), Andrew C Perkins, PhD

Blood (2016) 128 (22): 3881.

https://doi.org/10.1182/blood.V128.22.3881.3881

Published: 2016

Journal Articles

Characterisation of Novel Hypomorphic and Null Mutations in Klf1 Derived from a Genetic Screen for Modifiers of a -Globin Transgene Variegation

Stephen Huang, B Sc (Hons), Kevin R. Gillinder, PhD, Melissa Ilsley, BSc, Graham Magor, MB BS (Hons), Michael Tallack, MDPhD, Anabel Sorolla, B Sc PhD, Harald Oey, BSc PhD, Sarah Harten, BSc PhD, Lucia Clemens-Daxinger, BSc PhD, Emma Whitelaw, BSc PhD, Andrew C Perkins, MDPhD

Blood (2015) 126 (23): 3329.

https://doi.org/10.1182/blood.V126.23.3329.3329

Published: 2015

Journal Articles

Degenerate DNA Binding By Mutant (E339D) KLF1 Dramatically Alters the Erythroid Transcriptome in the Nan Mouse Model

Danitza Nebor, PhD, Raymond F. Robledo, PhD, Joel H. Graber, PhD, Omorose Aighewi, Lionel Blanc, PhD, Andrew C Perkins, Kevin R. Gillinder, PhD, James J. Bieker, PhD, Luanne L. Peters, PhD

Blood (2015) 126 (23): 932.

https://doi.org/10.1182/blood.V126.23.932.932

Published: 2015

Journal Articles

KLF1 -null neonates display hydrops fetalis and a deranged erythroid transcriptome

Graham W. Magor, Michael R. Tallack, Kevin R. Gillinder, Charles C. Bell, Naomi McCallum, Bronwyn Williams, Andrew C. Perkins

Blood (2015) 125 (15): 2405–2417.

https://doi.org/10.1182/blood-2014-08-590968

Published: 2015

Includes: Supplemental data

Journal Articles

Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271.

Ingrid G Winkler, PhD, Valerie Barbier, Andrew C Perkins, MDPhD, John L. Magnani, PhD, Jean-Pierre Levesque, PhD

Blood (2014) 124 (21): 317.

https://doi.org/10.1182/blood.V124.21.317.317

Published: 2014

Journal Articles

KLF1 Null Neonates Display Hydrops Fetalis and a Deranged Erythroid Transcriptome

Andrew C Perkins, MDPhD, Graham Magor, BSc, Michael R Tallack, BSc PhD, Kevin R Gillinder, BSc PhD, Charles Bell, BSc, Bronwyn Williams, MBBS,FRACP,FRCPA

Blood (2014) 124 (21): 2700.

https://doi.org/10.1182/blood.V124.21.2700.2700

Published: 2014

Journal Articles

New Insights into the Mechanism of Dominant Anemia Caused By Zinc Finger Mutations in KLF1

Andrew C Perkins, MDPhD, Kevin R Gillinder, BSc PhD, Graham Magor, BSc, Mathieu Lajoie, BSc PhD, Timothy L Bailey, BSc PhD, Michael R Tallack, BSc PhD, Melissa Ilsley, BSc, Michael Landsberg, BSc PhD, Joel P Mackay, PhD, James J. Bieker, PhD, Luanne L. Peters, PhD

Blood (2014) 124 (21): 740.

https://doi.org/10.1182/blood.V124.21.740.740

Published: 2014

Journal Articles

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Diwakar R. Pattabiraman, Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne, Ann Trezise, Jianmin Ding, Sean M. Grimmond, Peter Papathanasiou, Warren S. Alexander, Andrew C. Perkins, Jean-Pierre Levesque, Ingrid G. Winkler, Thomas J. Gonda

Blood (2014) 123 (17): 2682–2690.

https://doi.org/10.1182/blood-2012-02-413187

Published: 2014

Includes: Supplemental data

Journal Articles

Rapid Molecular Diagnosis Of JAK2V617F Negative MPN By Targeted Deep Sequencing Using The Ion Torrent PGM

Nathan Klose, BSc, Michael R Tallack, BSc PhD, Graham Magor, BSc, Peter Mollee, Andrew C Perkins, MB BS PhD

Blood (2013) 122 (21): 4093.

https://doi.org/10.1182/blood.V122.21.4093.4093

Published: 2013

Journal Articles

Dynamics and Mechanics Of KLF1 Regulation In Erythropoiesis

Kevin R. Gillinder, BSc PhD, Jim R. Hughes, Michael R. Tallack, BSc PhD, Graham Magor, BSc, Melissa Ilsley, BSc, James Davies, MD, Douglas Higgs, Andrew C. Perkins, MB BS PhD

Blood (2013) 122 (21): 2176.

https://doi.org/10.1182/blood.V122.21.2176.2176

Published: 2013

Journal Articles

Mutations In The Zinc Finger Domain Of Human and Mouse KLF1 Cause Congenital Dyserythropoietic Anemia (CDA) Via Promiscuous DNA Binding and Ectopic Target Gene Expression

Kevin R Gillinder, BSc PhD, Mathieu Lajoie, BSc PhD, Melissa Ilsley, BSc, Michael R Tallack, BSc PhD, Graham Magor, BSc, Michael Landsberg, BSc PhD, Timothy L Bailey, BSc PhD, Andrew C Perkins, MB BS PhD

Blood (2013) 122 (21): 11.

https://doi.org/10.1182/blood.V122.21.11.11

Published: 2013

Journal Articles

Interaction of c-Myb with p300 Is Required for the Induction of Acute Myeloid Leukemia by Human AML Oncogenes, and Represents a Potential Therapeutic Target.

Diwakar R Pattabiraman, PhD, Konstantin Shakhbazov, PhD, Valerie Barbier, Crystal McGirr, BSc (Hons), Keerthana Krishnan, BSc (Hons), Pamela Mukhopadhyay, PhD, Paula Hawthorne, PhD, Ann Trezise, PhD, Sean Grimmond, PhD, Peter Papathanasiou, Andrew C. Perkins, MBBS, PhD, FRACP, FRCPA, Jean-Pierre Levesque, PhD, Warren S. Alexander, Ingrid G Winkler, PhD, Thomas J Gonda, PhD

Blood (2012) 120 (21): 2402.

https://doi.org/10.1182/blood.V120.21.2402.2402

Published: 2012

Journal Articles

A recessive screen for genes regulating hematopoietic stem cells

Peter Papathanasiou, Robert Tunningley, Diwakar R. Pattabiraman, Ping Ye, Thomas J. Gonda, Belinda Whittle, Adam E. Hamilton, Simon O. Cridland, Rohan Lourie, Andrew C. Perkins

Blood (2010) 116 (26): 5849–5858.

https://doi.org/10.1182/blood-2010-04-269951

Published: 2010

Includes: Supplemental data

Journal Articles

Indian Hedgehog Is Essential for Definitive Haematopoiesis in the Fetal Liver.

Andrew C. Perkins, MBBS, PhD, Simon Cridland, BSc (Hons)

Blood (2007) 110 (11): 2192.

https://doi.org/10.1182/blood.V110.11.2192.2192

Published: 2007

NARROW

Longitudinal Assessment of Transfusion Intensity in Patients with JAK Inhibitor-Naive or -Experienced Myelofibrosis Treated with Momelotinib in the Phase 3 Simplify-1 and Momentum Trials

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

A Potential Role for Genes within the mTORC1 Pathway in the Regulation of Embryonic Globin Expression Revealed By ChIP-Seq, RNA-Seq and eQTL Mapping in the Nan Anemia Mouse Model

JAK1 Somatic Mutation in Myeloproliferative Neoplasm

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Mutations in the Second Linker of KLF1 Cause Congenital Non-Spherocytic Hemolytic Anemia Due to Global Reduction of In Vivo DNA-Binding Affinity

Direct Targets of Epo Receptor-JAK2-pSTAT5 Signalling in Erythropoiesis

Characterisation of Novel Hypomorphic and Null Mutations in Klf1 Derived from a Genetic Screen for Modifiers of a -Globin Transgene Variegation

Degenerate DNA Binding By Mutant (E339D) KLF1 Dramatically Alters the Erythroid Transcriptome in the Nan Mouse Model

KLF1 -null neonates display hydrops fetalis and a deranged erythroid transcriptome

Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271.

KLF1 Null Neonates Display Hydrops Fetalis and a Deranged Erythroid Transcriptome

New Insights into the Mechanism of Dominant Anemia Caused By Zinc Finger Mutations in KLF1

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Rapid Molecular Diagnosis Of JAK2V617F Negative MPN By Targeted Deep Sequencing Using The Ion Torrent PGM

Dynamics and Mechanics Of KLF1 Regulation In Erythropoiesis

Mutations In The Zinc Finger Domain Of Human and Mouse KLF1 Cause Congenital Dyserythropoietic Anemia (CDA) Via Promiscuous DNA Binding and Ectopic Target Gene Expression

Interaction of c-Myb with p300 Is Required for the Induction of Acute Myeloid Leukemia by Human AML Oncogenes, and Represents a Potential Therapeutic Target.

A recessive screen for genes regulating hematopoietic stem cells

Indian Hedgehog Is Essential for Definitive Haematopoiesis in the Fetal Liver.

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American Society of Hematology

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American Society of Hematology

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