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Journal Articles

Venetoclax Dose Escalation Rapidly Activates a BAFF/BCL-2 Survival Axis in Chronic Lymphocytic Leukemia

Blood blood.2024024341.

https://doi.org/10.1182/blood.2024024341

Published: 2024

Includes: Supplemental data

Journal Articles

Direct, Potent, and TP53-Independent Activity of Sting Agonists Against Acute Myeloid Leukaemia Enhances Venetoclax Efficacy In Vivo

Yin Yuan, Sarah T Diepstraten, Fiona C. Brown, Veronique Litalien, Andreas Strasser, Gemma L Kelly, Andrew W. Roberts, Andrew H. Wei

Blood (2023) 142 (Supplement 1): 4163.

https://doi.org/10.1182/blood-2023-179698

Published: 2023

Journal Articles

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Blood (2021) 137 (20): 2721–2735.

https://doi.org/10.1182/blood.2020010167

Published: 2021

Includes: Supplemental data

Journal Articles

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

Blood (2019) 133 (16): 1729–1741.

https://doi.org/10.1182/blood-2018-07-860726

Published: 2019

Includes: Supplemental data

Journal Articles

Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use

Margs S. Brennan, Catherine Chang, Lin Tai, Guillaume Lessene, Andreas Strasser, Grant Dewson, Gemma L. Kelly, Marco J. Herold

Blood (2018) 132 (15): 1573–1583.

https://doi.org/10.1182/blood-2018-06-859405

Published: 2018

Includes: Supplemental data

Journal Articles

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

Reema Jain, Julie M. Sheridan, Antonia Policheni, Melanie Heinlein, Luke C. Gandolfo, Grant Dewson, Gordon K. Smyth, Stephen N. Sansom, Nai Yang Fu, Jane E. Visvader, Georg A. Holländer, Andreas Strasser, Daniel H. D. Gray

Blood (2017) 130 (23): 2504–2515.

https://doi.org/10.1182/blood-2017-03-771576

Published: 2017

Includes: Supplemental data

Journal Articles

Mutant p53 Enhances the Development and Sustained Growth of MYC-Driven Lymphoma and Exerts a Dominant Negative Effect Preferentially Deregulating Pathways for Metabolism and DNA Repair

Brandon J Aubrey, MBBS, FRACP, FRCPA, Ana Janic, PhD, Yunshun Chen, PhD, Gordon K Smyth, PhD, Andrew J Kueh, PhD, Stephen Wilcox, PhD, Margs S Brennan, Lin Tai, Daniel HD Gray, PhD, Charis Teh, PhD, Ann Lin, Catherine Chang, Lorraine A O'Reilly, PhD, Marco J Herold, PhD, Andreas Strasser, MSc, PhD FAA, Gemma L Kelly, PhD

Blood (2016) 128 (22): 1545.

https://doi.org/10.1182/blood.V128.22.1545.1545

Published: 2016

Journal Articles

Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress

Alex R. D. Delbridge, Joseph T. Opferman, Stephanie Grabow, Andreas Strasser

Blood (2015) 125 (21): 3273–3280.

https://doi.org/10.1182/blood-2015-01-621250

Published: 2015

Includes: Supplemental data

Journal Articles

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

Bilal N. Sheikh, Stanley C. W. Lee, Farrah El-Saafin, Hannah K. Vanyai, Yifang Hu, Swee Heng Milon Pang, Stephanie Grabow, Andreas Strasser, Stephen L. Nutt, Warren S. Alexander, Gordon K. Smyth, Anne K. Voss, Tim Thomas

Blood (2015) 125 (12): 1910–1921.

https://doi.org/10.1182/blood-2014-08-594655

Published: 2015

Includes: Supplemental data

Journal Articles

MCL-1 but not BCL-XL is critical for the development and sustained expansion of thymic lymphoma in p53-deficient mice

Stephanie Grabow, Alex R. D. Delbridge, Liz J. Valente, Andreas Strasser

Blood (2014) 124 (26): 3939–3946.

https://doi.org/10.1182/blood-2014-09-601567

Published: 2014

Includes: Supplemental data

Journal Articles

Evidence for Mutant p53 Gain-of-Function Effects in Normal Haemopoietic Cells and Myc-Driven Lymphoma

Brandon James Aubrey, MBBS, FRACP, FRCPA, Andreas Strasser, PhD, Gemma Kelly, PhD, Lin Tai, Marco Herold, PhD

Blood (2014) 124 (21): 3589.

https://doi.org/10.1182/blood.V124.21.3589.3589

Published: 2014

Journal Articles

A Mouse Model for XLP-2 Disease Uncovers a Critical Function for IL-1beta and TNF in Driving Hyper-Inflammation

Philipp J. Jost, MD, Monica Yabal, PhD, Heiko Adler, PhD, Nathalie Knies, Christina Groß, Rune Busk Damgaard, Hirokazu Kanegane, MD PhD, Christian Peschel, MD, Andreas Strasser, PhD, Olaf Groß, Jürgen Ruland, MD, Mads Gyrd-Hansen, PhD

Blood (2014) 124 (21): 1403.

https://doi.org/10.1182/blood.V124.21.1403.1403

Published: 2014

Journal Articles

Plasmacytomagenesis in Eμ-v- abl transgenic mice is accelerated when apoptosis is restrained

Cassandra J. Vandenberg, Paul Waring, Andreas Strasser, Suzanne Cory

Blood (2014) 124 (7): 1099–1109.

https://doi.org/10.1182/blood-2014-04-570770

Published: 2014

Includes: Supplemental data

Journal Articles

Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf

Verena Labi, Claudia Woess, Selma Tuzlak, Miriam Erlacher, Philippe Bouillet, Andreas Strasser, Alexandar Tzankov, Andreas Villunger

Blood (2014) 123 (17): 2652–2662.

https://doi.org/10.1182/blood-2013-11-537217

Published: 2014

Includes: Supplemental data

Journal Articles

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

W. Wei-Lynn Wong, James E. Vince, Najoua Lalaoui, Kate E. Lawlor, Diep Chau, Aleksandra Bankovacki, Holly Anderton, Donald Metcalf, Lorraine O’Reilly, Philipp J. Jost, James M. Murphy, Warren S. Alexander, Andreas Strasser, David L. Vaux, John Silke

Blood (2014) 123 (16): 2562–2572.

https://doi.org/10.1182/blood-2013-06-510743

Published: 2014

Includes: Supplemental data

Journal Articles

Puma Is The Critical BH3-Only Protein Mediating Apoptosis In The Nup98-HoxD13 (NHD13) Mouse Model Of Human MDS

Andrew Guirguis, MBBS, FRACP, FRCPA, David J. Curtis, M.D., Ph.D., Christopher Slape, PhD, Jesslyn Saw, Andrew H Wei, MBBS, PhD, Laura M Failla, Philippe Bouillet, PhD, Andreas Strasser, PhD

Blood (2013) 122 (21): 1563.

https://doi.org/10.1182/blood.V122.21.1563.1563

Published: 2013

Journal Articles

Role of Bcl-2 Family in Lymphoid Malignancies

Andreas Strasser, PhD, G. Kelly, S. Glaser, S. Grabow, A. Delbridge, J.M. Adams, M. Herold

Blood (2013) 122 (21): SCI-41.

https://doi.org/10.1182/blood.V122.21.SCI-41.SCI-41

Published: 2013

Journal Articles

MCL-1 Critically Regulates Survival Of T-Lymphocyte Non-Hodgkin Lymphoma

Sabine Spinner, Kelly Gemma, PhD, Marco Herold, PhD, Konstanze Pechloff, PhD, Giuliano Crispatzu, Jürgen Ruland, MD, Marco Herling, MD, Christian Peschel, MD, Andreas Strasser, PhD, Philipp J. Jost, MD

Blood (2013) 122 (21): 4246.

https://doi.org/10.1182/blood.V122.21.4246.4246

Published: 2013

Journal Articles

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Emma C. Josefsson, Deborah L. Burnett, Marlyse A. Debrincat, Katya J. Henley, Rachael M. Lane, Marion Lebois, Lorraine A. O'Reilly, Marc Pellegrini, Simon P. Preston, Ben A. Croker, Donald Metcalf, Andreas Strasser, Benjamin T. Kile

Blood (2012) 120 (21): 389.

https://doi.org/10.1182/blood.V120.21.389.389

Published: 2012

Journal Articles

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

Christopher I. Slape, Jesslyn Saw, Jeremy B. M. Jowett, Peter D. Aplan, Andreas Strasser, Stephen M. Jane, David J. Curtis

Blood (2012) 120 (12): 2475–2483.

https://doi.org/10.1182/blood-2012-05-430736

Published: 2012

Includes: Supplemental data

NARROW

Venetoclax Dose Escalation Rapidly Activates a BAFF/BCL-2 Survival Axis in Chronic Lymphocytic Leukemia

Direct, Potent, and TP53-Independent Activity of Sting Agonists Against Acute Myeloid Leukaemia Enhances Venetoclax Efficacy In Vivo

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

Mutant p53 Enhances the Development and Sustained Growth of MYC-Driven Lymphoma and Exerts a Dominant Negative Effect Preferentially Deregulating Pathways for Metabolism and DNA Repair

Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

MCL-1 but not BCL-XL is critical for the development and sustained expansion of thymic lymphoma in p53-deficient mice

Evidence for Mutant p53 Gain-of-Function Effects in Normal Haemopoietic Cells and Myc-Driven Lymphoma

A Mouse Model for XLP-2 Disease Uncovers a Critical Function for IL-1beta and TNF in Driving Hyper-Inflammation

Plasmacytomagenesis in Eμ-v- abl transgenic mice is accelerated when apoptosis is restrained

Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

Puma Is The Critical BH3-Only Protein Mediating Apoptosis In The Nup98-HoxD13 (NHD13) Mouse Model Of Human MDS

Role of Bcl-2 Family in Lymphoid Malignancies

MCL-1 Critically Regulates Survival Of T-Lymphocyte Non-Hodgkin Lymphoma

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

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American Society of Hematology

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American Society of Hematology

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