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Rachael M. Lane
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Journal Articles

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Irina Pleines, Marion Lebois, Pradnya Gangatirkar, Amanda E. Au, Rachael M. Lane, Katya J. Henley, Maria Kauppi, Jason Corbin, Ping Cannon, Jonathan Bernardini, Imala Alwis, Kate E. Jarman, Sarah Ellis, Donald Metcalf, Shaun P. Jackson, Simone M. Schoenwaelder, Benjamin T. Kile, Emma C. Josefsson
Journal: Blood
Blood (2018) 132 (2): 197–209.
https://doi.org/10.1182/blood-2017-11-816355
Published: 2018
Includes: Supplemental data
Journal Articles

Extended Platelet In Vivo Survival Results in Exhausted Platelets

Irina Pleines, Marion Lebois, Amanda E.-L. Au, Rachael M. Lane, Katya J. Henley, Jason Corbin, Ping Cannon, Kate E Jarman, Sarah Ellis, Shaun P Jackson, Simone M. Schoenwaelder, Benjamin T. Kile, Emma C. Josefsson
Journal: Blood
Blood (2015) 126 (23): 416.
https://doi.org/10.1182/blood.V126.23.416.416
Published: 2015
Journal Articles

Mutations in Tropomyosin 4 Cause Macrothrombocytopenia in Mice and Humans

Irina Pleines, PhD, Joanne Woods, PhD, Ernest Turro, PhD, Nicola Foad, PhD, Stephane Chappaz, PhD, Rachael M. Lane, Harriet Manning, Galina Schevzov, PhD, Sarah K Westbury, Andrew D Mumford, Remi Favier, MD, Peter Gunning, PhD, Willem H. Ouwehand, MDPhDFRCPath FMedSci #, Marloes R Tijssen, PhD, Benjamin T Kile, PhD
Journal: Blood
Blood (2014) 124 (21): 571.
https://doi.org/10.1182/blood.V124.21.571.571
Published: 2014
Journal Articles

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Emma C. Josefsson, Deborah L. Burnett, Marlyse A. Debrincat, Katya J. Henley, Rachael M. Lane, Marion Lebois, Lorraine A. O'Reilly, Marc Pellegrini, Simon P. Preston, Ben A. Croker, Donald Metcalf, Andreas Strasser, Benjamin T. Kile
Journal: Blood
Blood (2012) 120 (21): 389.
https://doi.org/10.1182/blood.V120.21.389.389
Published: 2012
Journal Articles

Mcl-1 and Bcl-x L coordinately regulate megakaryocyte survival

Marlyse A. Debrincat, Emma C. Josefsson, Chloé James, Katya J. Henley, Sarah Ellis, Marion Lebois, Kelly L. Betterman, Rachael M. Lane, Kelly L. Rogers, Michael J. White, Andrew W. Roberts, Natasha L. Harvey, Donald Metcalf, Benjamin T. Kile
Journal: Blood
Blood (2012) 119 (24): 5850–5858.
https://doi.org/10.1182/blood-2011-12-398834
Published: 2012