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Matthew E Ritchie
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Journal Articles

Venetoclax Dose Escalation Rapidly Activates a BAFF/BCL-2 Survival Axis in Chronic Lymphocytic Leukemia

Meng-Xiao Luo, Tania Tan, Marie Trussart, Annika Poch, Minh-Hanh Thi Nguyen, Terence P. Speed, Damien G Hicks, Esther Bandala-Sanchez, Hongke Peng, Stephane Chappaz, Charlotte Slade, Daniel T Utzschneider, Rachel M Koldej, David Ritchie, Andreas Strasser, Rachel Thijssen, Matthew E Ritchie, Constantine Si Lun Tam, Geoffrey J Lindeman, David Ching Siang Huang, Professor, Thomas E Lew, Mary Ann Anderson, Andrew W Roberts, Charis E Teh, Daniel H D Gray
Journal: Blood
Blood blood.2024024341.
https://doi.org/10.1182/blood.2024024341
Published: 2024
Includes: Supplemental data
Journal Articles

Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy

Rachel Thijssen, Luyi Tian, Mary Ann Anderson, Christoffer Flensburg, Andrew Jarratt, Alexandra L. Garnham, Jafar S. Jabbari, Hongke Peng, Thomas E. Lew, Charis E. Teh, Quentin Gouil, Angela Georgiou, Tania Tan, Tirta M. Djajawi, Constantine S. Tam, John F. Seymour, Piers Blombery, Daniel H.D. Gray, Ian J. Majewski, Matthew E. Ritchie, Andrew W. Roberts, David C.S. Huang
Journal: Blood
Blood (2022) 140 (20): 2127–2141.
https://doi.org/10.1182/blood.2022016040
Published: 2022
Includes: Supplemental data
Journal Articles

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Catherine L. Carmichael, Jueqiong Wang, Thao Nguyen, Oluseyi Kolawole, Aissa Benyoucef, Charlotte De Mazière, Anna R. Milne, Sona Samuel, Kevin Gillinder, Soroor Hediyeh-zadeh, Anh N. Q. Vo, Yizhou Huang, Kathy Knezevic, William R. L. McInnes, Benjamin J. Shields, Helen Mitchell, Matthew E. Ritchie, Tim Lammens, Beatrice Lintermans, Pieter Van Vlierberghe, Nicholas C. Wong, Katharina Haigh, Julie A. I. Thoms, Emma Toulmin, David J. Curtis, Ethan P. Oxley, Ross A. Dickins, Dominik Beck, Andrew Perkins, Matthew P. McCormack, Melissa J. Davis, Geert Berx, Johannes Zuber, John E. Pimanda, Benjamin T. Kile, Steven Goossens, Jody J. Haigh
Journal: Blood
Blood (2020) 136 (8): 957–973.
https://doi.org/10.1182/blood.2019002548
Published: 2020
Includes: Supplemental data
Journal Articles

Uncovering Key Downstream Effectors of PU.1 Tumor Suppression in Acute Myeloid Leukemia

Margherita Ghisi, PhD, Mark D McKenzie, PhD, Ethan P Oxley, Emilia Simankowicz, Cynthia Liu, Aleksandar Dakic, PhD, Stephen L Nutt, PhD, Matthew E Ritchie, PhD, Johannes Zuber, MD PhD, Ross A Dickins, PhD
Journal: Blood
Blood (2016) 128 (22): 2698.
https://doi.org/10.1182/blood.V128.22.2698.2698
Published: 2016
Journal Articles

The Transcription Factor PU.1 Controls a Reversible Differentiation Program in Acute Myeloid Leukemia

Mark D McKenzie, PhD, Margherita Ghisi, PhD, Luisa Cimmino, PhD, Michael Erlichster, Ethan P Oxley, Cynthia Liu, Matthew T Witkowski, PhD, Grace Liu, PhD, Aleksandar Dakic, PhD, Emilia Simankowicz, Ladina DiRago, Donald Metcalf, MD, Stephen L Nutt, PhD, Meaghan Wall, MBBS, PhD FRACP, FRCPA, Matthew E Ritchie, PhD, Johannes Zuber, MD PhD, Ross A Dickins, PhD
Journal: Blood
Blood (2016) 128 (22): 3930.
https://doi.org/10.1182/blood.V128.22.3930.3930
Published: 2016
Journal Articles

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

Ian J. Majewski, Matthew E. Ritchie, Belinda Phipson, Jason Corbin, Miha Pakusch, Anja Ebert, Meinrad Busslinger, Haruhiko Koseki, Yifang Hu, Gordon K. Smyth, Warren S. Alexander, Douglas J. Hilton, Marnie E. Blewitt
Journal: Blood
Blood (2010) 116 (5): 731–739.
https://doi.org/10.1182/blood-2009-12-260760
Published: 2010
Includes: Supplemental data