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Yizhou Huang
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Journal Articles

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

Shruthi Subramanian, Julie A. I. Thoms, Yizhou Huang, Paola Cornejo-Páramo, Forrest C. Koch, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S. Woll, Diego Chacon-Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O'Brien, Annette Trickett, Jason A. Powell, Ian D. Lewis, Stuart M. Pitson, Maher K. Gandhi, Steven W. Lane, Fatemeh Vafaee, Emily S. Wong, Berthold Göttgens, Hamid Alinejad-Rokny, Jason W. H. Wong, John E. Pimanda
Journal: Blood
Blood (2023) 142 (17): 1448–1462.
https://doi.org/10.1182/blood.2023021120
Published: 2023
Includes: Supplemental data
Journal Articles

Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions

Shruthi Subramanian, Julie A.I. Thoms, Yizhou Huang, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S Woll, Diego Chacon Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O' Brien, Annette Trickett, Jason Powell, Stuart M Pitson, Maher K. Gandhi, Paola Cornejo, Emily Wong, Steven W Lane, Bertie Gottgens, Hamid Alinejad Rokny, Jason W.H Wong, John E. Pimanda
Journal: Blood
Blood (2022) 140 (Supplement 1): 2846–2848.
https://doi.org/10.1182/blood-2022-165620
Published: 2022
Journal Articles

Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells

Julie A. I. Thoms, Peter Truong, Shruthi Subramanian, Kathy Knezevic, Gregory Harvey, Yizhou Huang, Janith A. Seneviratne, Daniel R. Carter, Swapna Joshi, Joanna Skhinas, Diego Chacon, Anushi Shah, Ineke de Jong, Dominik Beck, Berthold Göttgens, Jonas Larsson, Jason W. H. Wong, Fabio Zanini, John E. Pimanda
Journal: Blood
Blood (2021) 138 (16): 1441–1455.
https://doi.org/10.1182/blood.2020009707
Published: 2021
Includes: Supplemental data
Journal Articles

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Catherine L. Carmichael, Jueqiong Wang, Thao Nguyen, Oluseyi Kolawole, Aissa Benyoucef, Charlotte De Mazière, Anna R. Milne, Sona Samuel, Kevin Gillinder, Soroor Hediyeh-zadeh, Anh N. Q. Vo, Yizhou Huang, Kathy Knezevic, William R. L. McInnes, Benjamin J. Shields, Helen Mitchell, Matthew E. Ritchie, Tim Lammens, Beatrice Lintermans, Pieter Van Vlierberghe, Nicholas C. Wong, Katharina Haigh, Julie A. I. Thoms, Emma Toulmin, David J. Curtis, Ethan P. Oxley, Ross A. Dickins, Dominik Beck, Andrew Perkins, Matthew P. McCormack, Melissa J. Davis, Geert Berx, Johannes Zuber, John E. Pimanda, Benjamin T. Kile, Steven Goossens, Jody J. Haigh
Journal: Blood
Blood (2020) 136 (8): 957–973.
https://doi.org/10.1182/blood.2019002548
Published: 2020
Includes: Supplemental data
Journal Articles

Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification

Diego Chacon, PhD, Ali Braytee, PhD, Yizhou Huang, PhD, Julie Thoms, PhD, Shruthi Subramanian, BSc, Maria Cristina Sauerland, Stefan K. Bohlander, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, MD, Wolfgang Hiddemann, MD PhD, Bogdan Gabrys, PhD, Klaus H. Metzeler, MD, Tobias Herold, MD, John Pimanda, MBBS, PhD, Dominik Beck, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1397.
https://doi.org/10.1182/blood-2019-129519
Published: 2019
Journal Articles

Shared roles for Scl and Lyl1 in murine platelet production and function

Sung K. Chiu, Stephanie L. Orive, Mitchell J. Moon, Jesslyn Saw, Sarah Ellis, Benjamin T. Kile, Yizhou Huang, Diego Chacon, John E. Pimanda, Dominik Beck, Justin R. Hamilton, Cedric S. Tremblay, David J. Curtis
Journal: Blood
Blood (2019) 134 (10): 826–835.
https://doi.org/10.1182/blood.2019896175
Published: 2019
Includes: Supplemental data
Journal Articles

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Ashwin Unnikrishnan, PhD, Elli Papaemmanuil, PhD, Dominik Beck, PhD, Arjun Verma, B.Sc., Ashu Kumari, PhD, Laura A. Richards, Kathy Knezevic, Vashe Chandrakanthan, PhD, Julie A.I. Thoms, PhD, Melinda L. Tursky, PhD, Yizhou Huang, Sally Galbraith, PhD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Magnus Tobiasson, MD, Petter S. Woll, PhD, Andrea Pellagatti, PhD, Susan R. Wilson, PhD, Robert Lindeman, MD, Jacqueline Boultwood, PhD, Kevin Lynch, MBBS, Sten Eirik Jacobsen, Ghulam J Mufti, FRCP, FRCPath, Eva Hellstrom-Lindberg, MD PhD, Karen Lee Mackenzie, PhD, Jason W.H. Wong, PhD, Peter J Campbell, MD PhD, John E. Pimanda, MDPhD
Journal: Blood
Blood (2015) 126 (23): 710.
https://doi.org/10.1182/blood.V126.23.710.710
Published: 2015
Journal Articles

Intron Retention Coupled with Nonsense-Mediated Decay Determines Protein Expression and Nuclear Morphology in Granulopoiesis

John Rasko, MBBS, PhD, Justin Wong, PhD, William Ritchie, PhD, Ebner Olivia, BSc, Selbach Matthias, PhD, Jason WH Wong, PhD, Yizhou Huang, BSc, Dadi Gao, BSc, Maria Gonzalez, MSc, Kinsha Baidya, BSc, Annora Theong, BSc, Teh-Liane Khoo, MBBS, Charles G Bailey, PhD, Jeff Holst, PhD
Journal: Blood
Blood (2012) 120 (21): 112.
https://doi.org/10.1182/blood.V120.21.112.112
Published: 2012