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Sylvie Shen
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Journal Articles

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

Shruthi Subramanian, Julie A. I. Thoms, Yizhou Huang, Paola Cornejo-Páramo, Forrest C. Koch, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S. Woll, Diego Chacon-Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O'Brien, Annette Trickett, Jason A. Powell, Ian D. Lewis, Stuart M. Pitson, Maher K. Gandhi, Steven W. Lane, Fatemeh Vafaee, Emily S. Wong, Berthold Göttgens, Hamid Alinejad-Rokny, Jason W. H. Wong, John E. Pimanda
Journal: Blood
Blood (2023) 142 (17): 1448–1462.
https://doi.org/10.1182/blood.2023021120
Published: 2023
Includes: Supplemental data
Journal Articles

Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions

Shruthi Subramanian, Julie A.I. Thoms, Yizhou Huang, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S Woll, Diego Chacon Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O' Brien, Annette Trickett, Jason Powell, Stuart M Pitson, Maher K. Gandhi, Paola Cornejo, Emily Wong, Steven W Lane, Bertie Gottgens, Hamid Alinejad Rokny, Jason W.H Wong, John E. Pimanda
Journal: Blood
Blood (2022) 140 (Supplement 1): 2846–2848.
https://doi.org/10.1182/blood-2022-165620
Published: 2022
Journal Articles

Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and Sumoylation Blockade in Myelodysplastic Syndromes and Acute Myeloid Leukemia

Peter Truong, Sylvie Shen, Swapna Joshi, Ali Afrasiabi, Ling Zhong, Mark J. Raftery, Jonas Larsson, Richard B. Lock, Carl R. Walkley, Hamid Alinejad Rokny, Julie A.I. Thoms, Christopher J. Jolly, John E. Pimanda
Journal: Blood
Blood (2022) 140 (Supplement 1): 220–221.
https://doi.org/10.1182/blood-2022-165713
Published: 2022
Journal Articles

5-Aza-2'-Deoxycytidine Promotes Cytotoxic Effect of CART-Cells on Leukaemia Cells

Alla Dolnikov, PhD, Swapna Rossi, Ning Xu, PhD, Guy Klamer, PhD, Sylvie Shen, PhD, Kenneth P. Micklethwaite, MD PhD, Richard B Lock, PhD, Tracey O'Brien, MD
Journal: Blood
Blood (2014) 124 (21): 5812.
https://doi.org/10.1182/blood.V124.21.5812.5812
Published: 2014
Journal Articles

Identifying the Factors Modulating the Efficacy of CAR-T Cell Therapy

Alla Dolnikov, PhD, Guy Klamer, PhD, Arjanna Chitranjan, Ning Xu, PhD, Sylvie Shen, PhD, Kenneth P. Micklethwaite, MD PhD, Richard B. Lock, PhD, Tracey O'Brien, MD
Journal: Blood
Blood (2014) 124 (21): 5813.
https://doi.org/10.1182/blood.V124.21.5813.5813
Published: 2014
Journal Articles

N-ras m -Transduced Fibroblasts Facilitate the Expansion and Engraftment of Umbilical Cord Blood Stem Cells.

Alla Dolnikov, PhD, Tiffany Holmes, MSc, Sylvie Shen, PhD, Robert Knight, MD, Tracey A. O’Brien, MBChB, FRACP, MHL, BSc
Journal: Blood
Blood (2006) 108 (11): 3196.
https://doi.org/10.1182/blood.V108.11.3196.3196
Published: 2006
Journal Articles

Defective P38 MAPK Signalling Impairs Chemotactic but Not Proliferative Responses to SDF-1 in Acute Lymphoblastic Leukemia.

Linda Bendall, Phd, Rana Baraz, BSc, Julius Juarez, BSc, Sylvie Shen, PhD, Ken Bradstock, MB, BS, PhD
Journal: Blood
Blood (2004) 104 (11): 997.
https://doi.org/10.1182/blood.V104.11.997.997
Published: 2004