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Carl R. Walkley
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Journal Articles

Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and Sumoylation Blockade in Myelodysplastic Syndromes and Acute Myeloid Leukemia

Peter Truong, Sylvie Shen, Swapna Joshi, Ali Afrasiabi, Ling Zhong, Mark J. Raftery, Jonas Larsson, Richard B. Lock, Carl R. Walkley, Hamid Alinejad Rokny, Julie A.I. Thoms, Christopher J. Jolly, John E. Pimanda
Journal: Blood
Blood (2022) 140 (Supplement 1): 220–221.
https://doi.org/10.1182/blood-2022-165713
Published: 2022
Journal Articles

Patience is a virtue

Carl R. Walkley
Journal: Blood
Blood (2022) 139 (4): 481–482.
https://doi.org/10.1182/blood.2021014427
Published: 2022
Journal Articles

Srsf2 P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells

Monique F. Smeets, Shuh Ying Tan, Jane Jialu Xu, Govardhan Anande, Ashwin Unnikrishnan, Alistair M. Chalk, Scott R. Taylor, John E. Pimanda, Meaghan Wall, Louise E. Purton, Carl R. Walkley
Journal: Blood
Blood (2018) 132 (6): 608–621.
https://doi.org/10.1182/blood-2018-04-845602
Published: 2018
Includes: Supplemental data
Journal Articles

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

Wei Shi, Therese Vu, Didier Boucher, Anna Biernacka, Jules Nde, Raj K. Pandita, Jasmin Straube, Glen M. Boyle, Fares Al-Ejeh, Purba Nag, Jessie Jeffery, Janelle L. Harris, Amanda L. Bain, Marta Grzelak, Magdalena Skrzypczak, Abhishek Mitra, Norbert Dojer, Nicola Crosetto, Nicole Cloonan, Olivier J. Becherel, John Finnie, Jeffrey R. Skaar, Carl R. Walkley, Tej K. Pandita, Maga Rowicka, Krzysztof Ginalski, Steven W. Lane, Kum Kum Khanna
Journal: Blood
Blood (2017) 129 (18): 2479–2492.
https://doi.org/10.1182/blood-2016-06-725093
Published: 2017
Includes: Supplemental data
Journal Articles

A-To-I RNA Editing By ADAR1 Is Essential For Hematopoiesis

Brian Liddicoat, Robert Piskol, Alistair Chalk, Miyoko Higuchi, Peter Seeburg, Jin Billy Li, Jochen Hartner, Carl R Walkley, PhD, BPharm
Journal: Blood
Blood (2013) 122 (21): 1199.
https://doi.org/10.1182/blood.V122.21.1199.1199
Published: 2013
Journal Articles

A Mouse Model Of Rothmund-Thomson Syndrome Reveals An Essential Role For Recql4 In Maintenance Of Hematopoiesis

Elisabetta DeLuca, Monique Smeets, Meaghan Wall, MBBS (Hons), FRACP, FRCPA, PhD, Julie Quach, Andrew Deans, Jorg Heierhorst, Louise E Purton, PhD, David Izon, Carl R Walkley, PhD, BPharm
Journal: Blood
Blood (2013) 122 (21): 591.
https://doi.org/10.1182/blood.V122.21.591.591
Published: 2013
Journal Articles

Modeling Myelodysplastic Syndromes In Mice By Altered Hoxa1 Spliceform Expression

Chacko Joseph, Jean Hendy, BSc, Stewart A Fabb, PhD, Emma K Baker, PhD, Alistair M Chalk, PhD, Carl R Walkley, PhD, BPharm, Lorraine J. Gudas, PhD, Meaghan Wall, MBBS (Hons), FRACP, FRCPA, PhD, Louise E Purton, PhD
Journal: Blood
Blood (2013) 122 (21): 97.
https://doi.org/10.1182/blood.V122.21.97.97
Published: 2013
Journal Articles

ADAR1 Is Essential For Erythroid Development

Brian Liddicoat, Jochen Hartner, Alistair Chalk, Jun Lu, PhD, Stuart H. Orkin, MD, Carl R Walkley, PhD, BPharm
Journal: Blood
Blood (2013) 122 (21): 9.
https://doi.org/10.1182/blood.V122.21.9.9
Published: 2013
Journal Articles

Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment

Sofie Singbrant, Megan R. Russell, Tanja Jovic, Brian Liddicoat, David J. Izon, Louise E. Purton, Natalie A. Sims, T. John Martin, Vijay G. Sankaran, Carl R. Walkley
Journal: Blood
Blood (2011) 117 (21): 5631–5642.
https://doi.org/10.1182/blood-2010-11-320564
Published: 2011
Includes: Multimedia, Supplemental data
Journal Articles

Rb Intrinsically Promotes Erythropoiesis by Coupling Cell Cycle Exit with Mitochondrial Biogenesis.

Vijay G. Sankaran, MPhil, Carl R. Walkley, Ph.D., Bruce M. Spiegelman, Ph.D., Stuart H. Orkin, M.D.
Journal: Blood
Blood (2007) 110 (11): 638.
https://doi.org/10.1182/blood.V110.11.638.638
Published: 2007
Journal Articles

Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis.

Trista E. North, PhD, Wolfram Goessling, MD, PhD, Kamden R. Kopani, Claudia Lengerke, MD, Carl R. Walkley, PhD, Allegra M. Lord, Il-ho Jang, Tilo Grosser, MD, Garret A. FitzGerald, MD, George Q. Daley, MD, PhD, Stuart H. Orkin, MD, Leonard I. Zon, MD
Journal: Blood
Blood (2006) 108 (11): 680.
https://doi.org/10.1182/blood.V108.11.680.680
Published: 2006
Journal Articles

Identification of the molecular requirements for an RARα-mediated cell cycle arrest during granulocytic differentiation

Carl R. Walkley, Louise E. Purton, Hayley J. Snelling, Yang-Dar Yuan, Hideaki Nakajima, Pierre Chambon, Roshantha A. S. Chandraratna, Grant A. McArthur
Journal: Blood
Blood (2004) 103 (4): 1286–1295.
https://doi.org/10.1182/blood-2003-07-2391
Published: 2004
Includes: Supplemental data