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Therese Vu
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Journal Articles

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

Sebastien Jacquelin, Jasmin Straube, Leanne Cooper, Therese Vu, Axia Song, Megan Bywater, Eva Baxter, Matthew Heidecker, Brad Wackrow, Amy Porter, Victoria Ling, Joanne Green, Rebecca Austin, Stephen Kazakoff, Nicola Waddell, Luke B. Hesson, John E. Pimanda, Frank Stegelmann, Lars Bullinger, Konstanze Döhner, Raajit K. Rampal, Dirk Heckl, Geoffrey R. Hill, Steven W. Lane
Journal: Blood
Blood (2018) 132 (26): 2707–2721.
https://doi.org/10.1182/blood-2018-04-846220
Published: 2018
Includes: Supplemental data
Journal Articles

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

Wei Shi, Therese Vu, Didier Boucher, Anna Biernacka, Jules Nde, Raj K. Pandita, Jasmin Straube, Glen M. Boyle, Fares Al-Ejeh, Purba Nag, Jessie Jeffery, Janelle L. Harris, Amanda L. Bain, Marta Grzelak, Magdalena Skrzypczak, Abhishek Mitra, Norbert Dojer, Nicola Crosetto, Nicole Cloonan, Olivier J. Becherel, John Finnie, Jeffrey R. Skaar, Carl R. Walkley, Tej K. Pandita, Maga Rowicka, Krzysztof Ginalski, Steven W. Lane, Kum Kum Khanna
Journal: Blood
Blood (2017) 129 (18): 2479–2492.
https://doi.org/10.1182/blood-2016-06-725093
Published: 2017
Includes: Supplemental data
Journal Articles

Crispr-Cas9 Mediated Disruption of Dnmt3a in JakV617F Hematopoietic Stem Cells Accelerates Disease Phenotype and Induces Lethal Myelofibrosis

Sebastien Jacquelin, PhD, Emma Dishington, Therese Vu, Axia Song, Matthew Heidecker, Solene Guignes, Claudia Bruedigam, PhD, Joanne Sutton, Geoffrey R Hill, MD PhD, Nicole Cloonan, PhD, Dirk Heckl, PhD, Steven W Lane, PhD
Journal: Blood
Blood (2016) 128 (22): 794.
https://doi.org/10.1182/blood.V128.22.794.794
Published: 2016
Journal Articles

SSB1/NABP2 and SSB2/NABP1 Have Essential and Overlapping Roles in Maintaining Hematopoietic Stem and Progenitor Cells

Wei Shi, PhD, Therese Vu, BSc, Glen Boyle, PhD, Fares Al-Ejeh, PhD, Tej Pandita, PhD, Krzysztof Ginalski, PhD, Maga Rowicka, PhD, Steven W. Lane, MD, Kum Kum Khanna, PhD
Journal: Blood
Blood (2015) 126 (23): 2405.
https://doi.org/10.1182/blood.V126.23.2405.2405
Published: 2015
Journal Articles

Cdx2 Cooperates with Flt3-ITD to Induce Acute Myeloid Leukaemia in Mice

Therese Vu, BSc, Claudia Bruedigam, Axia Song, Solene Guignes, Rebecca Austin, Sebastien Jacquelin, Alistair Chalk, Carl Walkley, PhD BPharm, Claudia Scholl, Stefan Fröhling, MD, Steven W. Lane, MD
Journal: Blood
Blood (2015) 126 (23): 557.
https://doi.org/10.1182/blood.V126.23.557.557
Published: 2015
Journal Articles

Autophagy is required for stem cell mobilization by G-CSF

Brief Report
Lucie Leveque-El Mouttie, Therese Vu, Katie E. Lineburg, Rachel D. Kuns, Frederik O. Bagger, Bianca E. Teal, Mary Lor, Glen M. Boyle, Claudia Bruedigam, Justine D. Mintern, Geoffrey R. Hill, Kelli P. A. MacDonald, Steven W. Lane
Journal: Blood
Blood (2015) 125 (19): 2933–2936.
https://doi.org/10.1182/blood-2014-03-562660
Published: 2015
Includes: Supplemental data
Journal Articles

Inhibition of Telomerase with Imetelstat Is Detrimental to Leukemia Stem Cells in Acute Myeloid Leukemia (AML)

Claudia Bruedigam, Frederik Otzen Bagger, Florian H Heidel, MD, Catherine Kuhn, Solene Guignes, Axia Song, Rebecca Austin, Therese Vu, Erwin M Lee, PhD, Andrew S. Moore, MBBS, FRACP, PhD, Richard B. Lock, PhD, Lars Bullinger, MD PhD, Geoff R Hill, MD, Steven W Lane, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2322.
https://doi.org/10.1182/blood.V124.21.2322.2322
Published: 2014
Journal Articles

Inhibition Of Telomerase Is a Novel and Effective Therapy In MLL-Rearranged Acute Myeloid Leukemia (AML)

Claudia Bruedigam, Frederik Otzen Bagger, MSc, Catherine Paine Kuhn, Therese Vu, Rebecca Austin, Florian H Heidel, MD, Lars Bullinger, MD, PhD, Geoff R Hill, Scott A. Armstrong, MD, PhD, David A. Williams, MD, Steven W Lane, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2887.
https://doi.org/10.1182/blood.V122.21.2887.2887
Published: 2013
Journal Articles

IL3-Receptor Signaling Is Dispensable For The Generation and Maintenance Of Jak2V617F-Induced Myeloproliferative Neoplasm (MPN

Therese Vu, Claudia Bruedigam, Rebecca Austin, Catherine Paine-Kuhn, Hayley S. Ramshaw, PhD, Angel F. Lopez, MBBS, PhD, Geoff Hill, MD, Ann Mullally, MD, Steven W Lane, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2841.
https://doi.org/10.1182/blood.V122.21.2841.2841
Published: 2013
Journal Articles

Autophagy Is Required For Long-Term Hematopoietic Stem Cell (HSC) Function and G-CSF-Induced HSC Mobilization

Lucie Leveque, Therese Vu, Rachel D Kuns, Bianca E Teal, Mary Lor, Katie E Lineburg, Claudia Bruedigam, Frederik Otzen Bagger, Glen Boyle, PhD, Geoffrey R Hill, Kelli P A MacDonald, PhD, Steven W Lane, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 892.
https://doi.org/10.1182/blood.V122.21.892.892
Published: 2013
Journal Articles

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera

Ann Mullally, Claudia Bruedigam, Luke Poveromo, Florian H. Heidel, Amy Purdon, Therese Vu, Rebecca Austin, Dirk Heckl, Lawrence J. Breyfogle, Catherine Paine Kuhn, Demetrios Kalaitzidis, Scott A. Armstrong, David A. Williams, Geoff R. Hill, Benjamin L. Ebert, Steven W. Lane
Journal: Blood
Blood (2013) 121 (18): 3692–3702.
https://doi.org/10.1182/blood-2012-05-432989
Published: 2013
Includes: Supplemental data