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Journal Articles

Critical role of tripartite fusion and LBD truncation in certain RARA - and all RARG -related atypical APL

Xiaosu Zhou, Xue Chen, Jiaqi Chen, Lijun Wen, Zhanglin Zhang, Ya-Zhen Qin, Panxiang Cao, Haizhou Xing, Yingchang Mi, Wei Wang, Guangsen Zhang, Ji Li, Huanling Wu, Zhifen Zhang, Jian Zhang, Zhan Su, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Ping Wu, Tong Wang, Gaowei Fan, Yang Zhao, David Jin, Xian Zhang, Xiujuan Ma, Qisheng Wu, Zhihua Zhang, Linya Wang, Futian Ma, Xia Xiao, Chengye Wu, Kai Sun, Ruijie Tang, Yun Zhang, Sanyun Wu, Ran Gao, Leping Zhang, Huyong Zheng, Yanli Zhao, Hong-Hu Zhu, Daopei Lu, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2024) 144 (14): 1471–1485.
https://doi.org/10.1182/blood.2024023883
Published: 2024
Includes: Supplemental data
Journal Articles

The Molecular Prognostic Scoring System for Normal Karyotype Myelodysplastic Syndromes

Wei Wang, Yudi Zhang, Wenli Yang, Yueyuan Han, Zheng Ge, Hongyan Tong
Journal: Blood
Blood (2023) 142 (Supplement 1): 4594.
https://doi.org/10.1182/blood-2023-182515
Published: 2023
Journal Articles

Long-Term Outcomes in Chronic Lymphocytic Leukemia Treated with Ibrutinib: 10-Year Follow-up of a Phase 2 Study

Andy Itsara, Clare Sun, Emily Bryer, Inhye E Ahn, Susan Soto, Hao-Wei Wang, Constance M. Yuan, Adrian Wiestner
Journal: Blood
Blood (2023) 142 (Supplement 1): 201.
https://doi.org/10.1182/blood-2023-182397
Published: 2023
Journal Articles

Ixazomib, Pomalidomide and Dexamethasone (IxaPD) Pan-Oral Regimen in the Treatment of Refractory and Relapsed Multiple Myeloma

Miao Chen, Rong Fu, Wenming Chen, Wei Wang, Yanping Ma, Junling Zhuang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6696.
https://doi.org/10.1182/blood-2023-187828
Published: 2023
Journal Articles

Flumatinib Versus Nilotinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

Suning Chen, Yanli Zhang, Na Xu, Hui Sun, Li Weiming, Yunfan Yang, Zunmin Zhu, Minghui Duan, Sixuan Qian, Yu Zhu, Jianmin Luo, Xiaodong Wang, Wei Yang, Weiying Gu, Fei Li, Bingcheng Liu, Yunxiao Xu, Zhenfang Liu, Chunling Wang, Yirong Jiang, Li Meng, Qin Wen, Yanli Xu, Xingli Zou, Wei Wang, Yan Xue, Hao Xu, Kehong Bi, Fuling Zhou, Liangming Ma, Rong Fu, Guifang Ouyang, Kaiyang Ding, Depei Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1797.
https://doi.org/10.1182/blood-2023-179073
Published: 2023
Journal Articles

Project Evolve, Evaluation of Lineage Switch (LS), an International Initiative: Preliminary Results Reveal Dismal Outcomes in Patients with LS

Sara K. Silbert, Cynthia Harrison, D. Nathan Biery, Alexandra Semchenkova, Elena Zerkalenkova, Anna Alonso-Saladrigues, Kaylyn Utley, Ibrahim Aldoss, Liping Zhao, Sneha Fernandes, Jeremy D. Rubinstein, Naomi Torres Carapia, Bill H. Chang, Anant Vatsayan, Barbara De Moerloose, Holly L. Pacenta, Dennis John Kuo, Gabriele Escherich, Benjamin J. Lee, Michele S. Redell, Mandi R. Fitzjohn, Daniel P. Larson, Nicolas Duployez, Raymund S. Cuevo, Rui Rochelle He, David Dickens, Firas El Chaer, Kelly Reed, Matthias Wolfl, Sunil S. Raikar, Süreyya Savaşan, Latika Puri, Zhubin J. Gahvari, Aimee C. Talleur, Hisham Abdel-Azim, Aghiad Chamdin, Marlie R.M. Provost, Vanessa A. Fabrizio, Kerstin Mezger, Alexandra McLean Stevens, Emily M. Hsieh, Hao-Wei Wang, Constance M. Yuan, Ulrich A. Duffner, Jing Pan, Sara Ghorashian, Susana Rives, Chloe Hoang, Kara L. Davis, Elad Jacoby, Alexander Popov, Adam Lamble, Nirali N. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 4202.
https://doi.org/10.1182/blood-2023-182293
Published: 2023
Journal Articles

A Phase II Study of Vibecotamab, a CD3-CD123 Bispecific T-Cell Engaging Antibody, for MDS or CMML after Hypomethylating Failure and in MRD-Positive AML

Daniel Nguyen, Farhad Ravandi, Sa A. Wang, Jeffrey L. Jorgensen, Wei Wang, Kelly S. Chien, Guillermo Montalban-Bravo, Ghayas C. Issa, Abhishek Maiti, Yesid Alvarado Valero, Naval Daver, Courtney D. DiNardo, Elias Jabbour, Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Jaehyun Lee, Pavan Bachireddy, Uday R. Popat, Guillermo Garcia-Manero, Hagop M. Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2023) 142 (Supplement 1): 322.
https://doi.org/10.1182/blood-2023-190693
Published: 2023
Journal Articles

SETDB1 Suppresses Interferon Responses and NK Cell-Mediated Immunosurveillance Specifically in Monocytic AML

Yu-Hsuan Chang, Keita Yamamoto, Takeshi Fujino, Teh-Wei Wang, Emi Sugimoto, Wenyu Zhang, Tomohiro Yabushita, E. Christine Pietsch, Barbara A. Weir, Ramona Crescenzo, Glenn S. Cowley, Ricardo M. Attar, Ulrike Philippar, Yutaka Enomoto, Yoichi Imai, Toshio Kitamura, Susumu Goyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 713.
https://doi.org/10.1182/blood-2023-177531
Published: 2023
Journal Articles

CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML: Dose-Escalation Results from a Phase I/II Multicenter Trial

Nirali N. Shah, Sarah K. Tasian, M. Eric Kohler, Emily M. Hsieh, Susanne H.C. Baumeister, Corinne Summers, Haneen Shalabi, Jessica A. Pollard, Bonnie Yates, Ruta Brazauskas, Eric Ndifon, Constance M. Yuan, Hao-Wei Wang, Hati K Kobusingye, Kayla Christianson, Allison A Weiss, Erin Leckrone, Bronwen E. Shaw, Jeffery J. Auletta, Hemalatha G. Rangarajan, John Roach, Julie Blake, Dennis Michiel, Brian Bowser, Sheryl Ruppel, George Mitra, Anthony Welch, Jason Yovandich, Rachelle Salomon, Leslie Kean, Katherine Tarlock, Michael A. Pulsipher, Michael R Verneris, Larisa Broglie, Terry J. Fry, Steven M. Devine, Richard Aplenc
Journal: Blood
Blood (2023) 142 (Supplement 1): 771.
https://doi.org/10.1182/blood-2023-179667
Published: 2023
Journal Articles

Does Detection of <20% Lymphoblasts in Patients with CML Herald Imminent Blast Crisis? a Study from BCR::ABL1 Pathology Group

Zimu Gong, Lianqun Qiu, Joseph DiGiuseppe, Mengxing Xue, Lorinda Soma, Wei Wang, Yi Zhou, Qi Shen, Mingqing Zhu, Anisha Naik, Weina Chen, Wei J Wang, Sa A. Wang, L. Jeffrey Medeiros, Elias Jabbour, Hagop M. Kantarjian, Jorge Cortes, Jerald P. Radich, Joseph D. Khoury, Andreas Hochhaus, Jane F Apperley, Suning Chen, Kikkeri N Naresh, Shimin Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2023-187020
Published: 2023
Journal Articles

The Efficacy and Safety of Selinexor in Combination with Ruxolitinib in Ruxolitinib-Treated Myelofibrosis Patients： the Interim Analysis of a Prospective, Open-Label, Multicenter, Parallel-Cohort, Phase 2 Study

Minghui Duan, Lan Ma, Qiuling Wu, Hong Liang, Wei Wang, Shaoling Wu, Lijun Mu, Hai Lin, Hebing Zhou, Hong-Xia Shi, Jinghua Wang, Hongmei Jing
Journal: Blood
Blood (2023) 142 (Supplement 1): 4578.
https://doi.org/10.1182/blood-2023-188037
Published: 2023
Journal Articles

Gene Expression Profiling Reveals Two Overarching Types of Anaplastic Large Cell Lymphoma with Distinct Targetable Biology: An L.L.M.P.P. Study

Andrew L. Feldman, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Naoki Oishi, Catalina Amador, Elias Campo, Wing C. Chan, James R. Cook, Jan Delabie, Pedro Farinha, Kai Fu, Timothy C. Greiner, Giorgio Inghirami, Javeed Iqbal, Elaine S. Jaffe, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Phil Raess, Andreas Rosenwald, Kerry J. Savage, Graham Slack, Susan L. Slager, Joo Y. Song, Louis M. Staudt, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A. Wilcox, Xueju Wang, Akira Satou, Anamarija M. Perry, Roberto Miranda, L. Jeffrey Medeiros, Matthew J. Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S. Kahl, Liuyan Jiang, David L Jaye, Laurence de Leval, Weina Chen, Jennifer R. Chapman-Fredricks, James R. Cerhan, Carlos Barrionuevo, Stephen M Ansell, Ahmed Aljudi
Journal: Blood
Blood (2023) 142 (Supplement 1): 847.
https://doi.org/10.1182/blood-2023-186969
Published: 2023
Journal Articles

Ibrutinib, Fludarabine, Cyclophosphamide and Obinutuzumab (iFCG) for Firstline Treatment of Patients with CLL with Mutated IGHV and without Del(17p)/ TP53 Mutation: Six-Year Follow-up Analyses

Nitin Jain, Philip Thompson, Akhil Jain, Jan A. Burger, Alessandra Ferrajoli, Jayastu Senapati, Koichi Takahashi, Mahesh Swaminathan, Zeev Estrov, Gautam Borthakur, Prithviraj Bose, Tapan M. Kadia, Naveen Pemmaraju, Koji Sasaki, Divyam Bansal, Marina Y. Konopleva, Elias Jabbour, Naveen Garg, Xuemei Wang, Rashmi Kanagal-Shamanna, Keyur P. Patel, Wei Wang, Sa A. Wang, Jeffrey L. Jorgensen, Wanda Lopez, Ana Ayala, William Plunkett, Varsha Gandhi, Hagop M. Kantarjian, Susan M. O'Brien, Michael J. Keating, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 3267.
https://doi.org/10.1182/blood-2023-188084
Published: 2023
Journal Articles

Partner Gene Associated Trinary Fusion and Orchestration of Multiple Molecular Events in Acute Promyelocytic Leukemia with Variant Rara Fusion Genes

Jiaqi Chen, Lijun Wen, Xiaosu Zhou, Xue Chen, Zhanglin Zhang, Panxiang Cao, Fang Wang, Yang Zhang, Xiaoli Ma, Jiangcheng Fang, Ping Wu, Tong Wang, Zhihua Zhang, Linya Wang, Huyong Zheng, Ruijie Tang, Wei Wang, Wanting He, Siyuan Liu, David Jin, Xian Zhang, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1414.
https://doi.org/10.1182/blood-2023-187869
Published: 2023
Journal Articles

Analysis of Clinical Features, Prognostic Characteristics and Gene Mutations of the EB Subtype of Primary Myelodysplastic Syndrome Patients with Myelofibrosis

Gaixiang Xu, Wei Wang, Shuanghong Zhu, Kongfei Li, Xinping Zhou, Liya Ma, Li Ye, Chen Mei, Lu Wang, Lingxu Jiang, Haitao Meng, Wen-Juan Yu, Jie Jin, Hongyan Tong, Jian Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6481.
https://doi.org/10.1182/blood-2023-184789
Published: 2023
Journal Articles

The Reversible BTK Inhibitor Nemtabrutinib Demonstrates Favorable Antitumor Efficacy and Enhances the Function of CAR T Cells in Mantle Cell Lymphoma

Margaret Elizabeth Simmons, Joseph McIntosh, Tianci Zhang, Yijing Li, Fangfang Yan, Yixin Yao, Lei Nie, Heng-Huan Lee, Wei Wang, Vivian Changying Jiang, Michael Wang, Yang Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 5789.
https://doi.org/10.1182/blood-2023-187405
Published: 2023
Journal Articles

Phase I Open-Label Single-Arm Study of Sscart-19 in Adult Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in China

Liqing Kang, Shengli Xue, Xiaowen Tang, Xiaoyan Lou, Chongsheng Qian, Wenjie Gong, Mingzhu Xu, Haixia Zhou, Zhen Yao, Wei Wang, Minghao Li, Nan Xu, Zhou Yu, Suning Chen, Huiying Qiu, Haiping Dai, Yang Xu, Depei Wu, Lei Yu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3477.
https://doi.org/10.1182/blood-2023-181552
Published: 2023
Journal Articles

Trinary Fusion with Ligand Binding Domain Castration Is Crucial in Rarg -Driven APL and Render Unresponsive to ATRA Via Allosteric Disability Mechanism

Xiaosu Zhou, Xue Chen, Ya-Zhen Qin, Zhanglin Zhang, Jiaqi Chen, Lijun Wen, Panxiang Cao, Yingchang Mi, Wei Wang, Huanling Wu, Guangsen Zhang, Ji Li, Zhifen Zhang, Jian Zhang, Zhan Su, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Ping Wu, Tong Wang, Ruijie Tang, Wanting He, Yang Zhao, Ran Gao, Honghu Zhu, Siyuan Liu, David Jin, Xian Zhang, Leping Zhang, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2949.
https://doi.org/10.1182/blood-2023-185483
Published: 2023
Journal Articles

Efficacy and Safety of Interleukin-6-Knockdown CD19-Targeted CAR T Cells(ssCART-19) for Relapsed/Refractory B-ALL

Liqing Kang, Jinfeng Ma, Xiaoyan Lou, Xiaowen Tang, Shengli Xue, Suning Chen, Huiying Qiu, Miao Miao, Yue Han, Ying Wang, Aining Sun, Haiping Dai, Yang Xu, Limin Li, Shengjin Fan, Chongsheng Qian, Wenjie Gong, Mingzhu Xu, Haixia Zhou, Zhen Yao, Wei Wang, Minghao Li, Nan Xu, Zhou Yu, Depei Wu, Lei Yu
Journal: Blood
Blood (2023) 142 (Supplement 1): 889.
https://doi.org/10.1182/blood-2023-172615
Published: 2023
Journal Articles

Fixed Duration Combination Therapy with Carfilzomib, Lenalidomide, and Dexamethasone Followed By Lenalidomide Maintenance Leads to High Rates of Sustained MRD Negativity in Patients with High-Risk Smoldering Multiple Myeloma: Long Term Follow up of an Investigator Initiated Phase 2 Trial

Elizabeth Hill, Joseph L. Roswarski, Amrit Bhaskarla, Alexander Dew, Candis Morrison, Michael Emanuel, Ani Petrosyan, Hao-Wei Wang, Constance M. Yuan, Liza Lindenberg, Esther Mena, Baris Turkbey, Nisha Patel, Irina Maric, Alina Dulau-Florea, Katherine Calvo, Raul C. Braylan, Maryalice Stetler-Stevenson, Seth M. Steinberg, William Figg, Ryan M. Young, Ola Landgren, Mark Roschewski, Dickran Kazandjian
Journal: Blood
Blood (2023) 142 (Supplement 1): 337.
https://doi.org/10.1182/blood-2023-181811
Published: 2023