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Journal Articles

CD19/22 CAR T-cells in children and young adults with B-ALL: Final Phase 1 trial results

Free
Sara Silbert, Flavia Gava, Bonnie Yates, Alexander Rankin, Lauren Little, Toni Foley, Alexandra Dreyzin, Christopher Chien, Naomi Taylor, Terry Fry, Constance Yuan, Hao-Wei Wang, David Stroncek, Steven Highfill, Haneen Shalabi, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 814.
https://doi.org/10.1182/blood-2025-814
Published: 2025
Journal Articles

From bench to IND: Validation of TSLPR CAR T-cells reveal discrepancies in detection modalities and inform dose selection for a Phase 1 clinical trial in relapsed/refractory CRLF2-rearranged B-ALL patients.

Free
Christopher Chien, Marie Pouzolles, Angela Su, Hannah Song, Brynn Duncan, Dina Schneider, Rimas Orentas, Haneen Shalabi, Sarah Tasian, Terry Fry, Steven Highfill, Nirali Shah, Naomi Taylor
Journal: Blood
Blood (2025) 146 (Supplement 1): 4101.
https://doi.org/10.1182/blood-2025-4101
Published: 2025
Journal Articles

Utility of peripheral blood cell-free DNA in detecting minimal residual disease in patients receiving CAR T-cell therapy for B-acute lymphoblastic leukemia (B-ALL)

Free
Yannan Wang, Xiaolin Wu, Brynn Duncan, Chloe Hoang, Bonnie Yates, Chloe Sachs, Victoria Giordani, Nirali Shah, Russell Sundby
Journal: Blood
Blood (2025) 146 (Supplement 1): 1591.
https://doi.org/10.1182/blood-2025-1591
Published: 2025
Journal Articles

Early use of talicabtagene autoleucel in r/r B-acute lymphoblastic leukemia is cost-effective: Improved efficacy, reduced toxicity and healthcare resource utilization support affordable access

Free
Atharva Karulkar, Hasmukh Jain, Devanshi Kalra, Smrithi Ravikumar, Anand Vaibhaw, Shreshtha Shah, Afrin Firfiray, Juber Pendhari, Neeraj Siddarthan, Pavan Kumar Boyella, Sanket Shah, Sameer Melinkeri, Anshul Gupta, Prashant Mehta, Chandran Nair, Dinesh Bhurani, Akshay Lahoti, Anupam Chakrapani, Balakrishna Padate, Prakash Shekhawat, Priyanka Samal, Rajat Bajaj, Rumesh Chandar, Padmaja Lokireddy, Anil Aribandi, Bhausaheb Bagal, Girish Badarkhe, Jayachandran P.K., Kripa Bajaj, Nataraj KS, Nishad Dhakate, Rajan Kapoor, Rahul Bhargava, Sameer Tulpule, Sharat Damodar, Sunil Gupta, Suraj Chiraniya, Suvir Singh, Rajasekar Thirugnanam, Vasu Babu Goli, Vikram Mathews, Esha Kaul, Krishna Reddy Golamari, Kannan Subramanian, Lingaraj Nayak, Alok Shetty, Aditya Murali, Punit Jain, Rajat Bhattacharyya, Rakesh Boya, Ram Abhinav, Velu Nair, Hari Menon, Monisha Harimadhavan, Mohammed Sadique Ansari, Nishant Tiwari, Shamil Darbar, Supriya Chawkekar, Sushmita Sahay, Manivasagam Sundharam, Ashish Saroha, Moumita Basu, Anjali Jaiswal, Yuktam Yadav, Sakshi Soni, Jayshree Thorat, Shalini Purwar, Nirali Shah, Terry Fry, Nitin Jain, Manju Sengar, Rahul Purwar
Journal: Blood
Blood (2025) 146 (Supplement 1): 1076.
https://doi.org/10.1182/blood-2025-1076
Published: 2025
Journal Articles

Evaluating flow cytometry (FC) and next generation sequencing (NGS) for assessing minimal residual disease (MRD) and B-cell aplasia (BCA) in children, adolescents and young adults (CAYA) with B-cell acute lymphoblastic leukemia (B-ALL)

Free
Chelsea O'Koren, Julie Ma, Bonnie Yates, Hao-Wei Wang, Constance Yuan, Chloe Hoang, Tanvi Verma, David Peske, Ilan Kirsch, Challice Bonifant, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 3363.
https://doi.org/10.1182/blood-2025-3363
Published: 2025
Journal Articles

Optimal therapy for pediatric B-ALL in first relapse: Comparative effectiveness of blinatumomab to hematopoietic cell transplantation versus CD19 CAR T cell therapy

Free
Regina Myers, Yimei Li, Hongyan Liu, Alex Hoover, Laura Shinehouse, Ashley Hinson, Mira Kohorst, Anna Elias, Ella Keenan, Hannah Acres, Ibrahim Ahmed, Abdulla Al-Mulla, Laura Arthur, Jill Beck, Abigale Berry, Deepika Bhatla, Eliza Briscoe, Grace Chang, Roland Chu, Laurie Davis, J. Gregory Dolan, Lyannette Elo, Elizabeth Eom, Alejandra Escobar Vasco, Vanessa Fabrizio, Kelly Faulk, Victor Galan-Gomez, Erin Goode, Stephan Grupp, Anurekha Hall, Darcy Hamill, Smitha Vasanna, Hannah Kinoshita, Elizabeth Krieger, Cathy Lee-Miller, Katherine Lind, Jordan Milner, Giselle Moore-Higgs, Amy Moskop, Lindsey Murphy, Megan Murphy, Gabriella Nguyen, Maria Ortega, Hiren Patel, Antonio Perez, Thomas Pfeiffer, Alexandra Prosser-Dombrowski, Mahvish Rahim, April Rahrig, Shanti Ramachandran, Miza Salim Hammoud, Amanda Saraf, Jamie Shoag, Heather Symons, Nicholas Tastet, Stephanie Thomas, Molly Thornock, Keri Toner, Allison Weisnicht, Sara Zarnegar-Lumley, Nirali Shah, Shannon Maude, Jeremy Rubinstein, Troy Quigg, Deepa Bhojwani, Caitlin Elgarten
Journal: Blood
Blood (2025) 146 (Supplement 1): 3339.
https://doi.org/10.1182/blood-2025-3339
Published: 2025
Journal Articles

CRLF2-rearrangement and extramedullary disease in B-cell acute lymphoblastic leukemia: A possible link?

Free
Flavia Mesquita Gava, Bonnie Yates, Grace Li, Chelsea O'Koren, Biplov Adhikari, Haneen Shalabi, Evrim Turkbey, Constance Yuan, Hao-Wei Wang, Sara Silbert, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 5099.
https://doi.org/10.1182/blood-2025-5099
Published: 2025
Journal Articles

Disparate post-relapse survival outcomes by race/ethnicity for children with B-cell acute lymphoblastic leukemia: An analysis from the recall-1 study

Free
Abigale Berry, Caitlin Elgarten, Yimei Li, Hongyan Liu, Katherine Lind, Daniel Zheng, Gabriella Nguyen, Vanessa Fabrizio, Maria Ortega, Jeremy Rubinstein, Troy Quigg, Anurekha Hall, Deepa Bhojwani, Nirali Shah, Shannon Maude, Sara Zarnegar-Lumley, Allison Weisnicht, Keri Toner, Molly Thornock, Stephanie Thomas, Nicholas Tastet, Heather Symons, Jamie Shoag, Amanda Saraf, April Rahrig, Mahvish Rahim, Alexandra Prosser-Dombrowski, Thomas Pfeiffer, Hiren Patel, Megan Murphy, Lindsey Murphy, Amy Moskop, Giselle Moore-Higgs, Jordan Milner, Kevin McNerney, Cathy Lee-Miller, Mira Kohorst, Hannah Kinoshita, Elizabeth Krieger, Smitha Vasanna, Alex Hoover, Ashley Hinson, Miza Salim Hammoud, Darcy Hamill, Erin Goode, Kelly Faulk, Alejandra Escobar Vasco, Lyannette Elo, Anna Elias, Elizabeth Eom, Jennifer Drinkwine, J. Gregory Dolan, Laurie Davis, Roland Chu, Eliza Briscoe, Deepika Bhatla, Jill Beck, Abdulla Al-Mulla, Ibrahim Ahmed, Lena Winestone, Regina Myers
Journal: Blood
Blood (2025) 146 (Supplement 1): 4525.
https://doi.org/10.1182/blood-2025-4525
Published: 2025
Journal Articles

SPPL3-glycosylation axis governs CD22 CAR T-cell susceptibility in B-ALL independent of antigen recognition

Free
Jaehyun Suh, Ukhyun Jo, Craig Thomas, Nirali Shah, Jack Shern, Christopher Chien, Naomi Taylor
Journal: Blood
Blood (2025) 146 (Supplement 1): 2347.
https://doi.org/10.1182/blood-2025-2347
Published: 2025
Journal Articles

Firicabtagene autoleucel (firi-cel), a CD22-directed CAR T-cell therapy, for patients with relapsed/refractory large B-cell lymphoma: Results from the phase 2 study (FIRCE-1 Trial)

Free
Matthew Frank, David Qualls, Armin Ghobadi, Jordan Gauthier, Michael Tees, Luke Mountjoy, Joseph McGuirk, Sattva Neelapu, Reem Karmali, Iris Isufi, Brian Hill, Craig Sauter, Catherine Diefenbach, Jay Spiegel, Lizamarie Bachier-Rodriguez, Monalisa Ghosh, Nirav Shah, Rahul Lakhotia, Francisco Hernandez-Ilizaliturri, Anuja Abhyankar, Elise Chong, Matthew Schwede, Krish Patel, Olalekan Oluwole, John Baird, Nathan Denlinger, Farrukh Awan, Michael Jain, John Timmerman, Cesar Sanchez, Muthu Kumaran, Jean Yared, Jon Arnason, Ishan Tatake, Usama Gergis, Peter Riedell, Keith Pratz, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 667.
https://doi.org/10.1182/blood-2025-667
Published: 2025
Journal Articles

Real-world outcomes of immune effector cell-associated hemophagocytic syndrome (IEC-HS) following ide-cel and cilta-cel therapy in relapsed/refractory multiple myeloma

Free
Jerry Lee, Alexandria Jensen, Hitomi Hosoya, Aimaz Afrough, Saurabh Zanwar, Oren Pasvolsky, Mahmoud Gaballa, Christen Dillard, Jack Khouri, Shahzad Raza, Utkarsh Goel, Faiz Anwer, Vanna Hovanky, Masooma Rana, James Davis, Kimberly Green, Larry Anderson, Noa Biran, Eli Zolotov, Megan Herr, Hamza Hassan, Leyla Shune, Jeries Kort, Christopher Ferreri, Shebli Atrash, Cindy Varga, Peter Voorhees, Douglas Sborov, Gliceida Fortuna, Kelley Julian, Danai Dima, Andrew Portuguese, Rahul Banerjee, Ciara Louise Freeman, Karla Feliciano Salva, Raffaella Cassano Cassano, Lauren Peres, Brett Reid, Omar Alexis Castaneda Puglianini, Ariel Grajales-Cruz, Michael Jain, Krina Patel, Frederick Locke, Matthew Frank, Yi Lin, Doris Hansen, Surbhi Sidana, Nirali Shah, Lekha Mikkilineni
Journal: Blood
Blood (2025) 146 (Supplement 1): 719.
https://doi.org/10.1182/blood-2025-719
Published: 2025
Journal Articles

Optimal ferritin threshold to diagnose immune effector cell-associated hemophagocytic syndrome (IEC-HS) following CAR-T therapy in relapsed/refractory multiple myeloma (RRMM)

Free
Jerry Lee, Alexandria Jensen, Hitomi Hosoya, Saurabh Zanwar, Oren Pasvolsky, Mahmoud Gaballa, Christen Dillard, Jack Khouri, Shahzad Raza, Utkarsh Goel, Faiz Anwer, Vanna Hovanky, Masooma Rana, James Davis, Kimberly Green, Aimaz Afrough, Larry Anderson, Noa Biran, Eli Zolotov, Megan Herr, Hamza Hassan, Leyla Shune, Jeries Kort, Christopher Ferreri, Shebli Atrash, Cindy Varga, Peter Voorhees, Douglas Sborov, Gliceida Fortuna, Kelley Julian, Danai Dima, Rahul Banerjee, Ciara Louise Freeman, Andrew Portuguese, Raffaella Cassano Cassano, Frederick Locke, Karla J Salva, Lauren Peres, Brett Reid, Omar Alexis Castaneda Puglianini, Ariel Grajales-Cruz, Michael Jain, Krina Patel, Matthew Frank, Yi Lin, Doris Hansen, Surbhi Sidana, Nirali Shah, Lekha Mikkilineni
Journal: Blood
Blood (2025) 146 (Supplement 1): 717.
https://doi.org/10.1182/blood-2025-717
Published: 2025
Journal Articles

Single-cell metabolic profiling of post-infusion CD22 and CD19/CD22 CAR T-cells reveals a shift toward amino acid–driven oxphos informing SLC-armored CAR design

Free
Josquin Moraly, Taisuke Kondo, Sooraj Achar, Mehdi Benzaoui, Saliha Majdoul, Justin Mirazee, Jaehyun Suh, Alka Dwivedi, Christopher Chien, Makoto Ando, Angela Su, King Chan, Hannah Dada, Valerie Dardalhon, Cedric Mongellaz, Bonnie Yates, Olivier Hermine, Ye Yang, Krithika Bhuvaneshwar, Daniel Crooks, Thorkell Andresson, Gregoire Altan-Bonnet, Nirali Shah, Naomi Taylor
Journal: Blood
Blood (2025) 146 (Supplement 1): 502.
https://doi.org/10.1182/blood-2025-502
Published: 2025
Journal Articles

A novel immune signature characterized by activation of the IFNγ-IL18 axis identifies immune effector cell-associated HLH-like syndrome after CD22 chimeric antigen receptor T-cell therapy

Free
Joseph Rocco, Brett Schroeder, Logan Cook, Bonnie Yates, Brian Sellers, Thomas Langowski, Colton McNinch, Irina Maric, Michelly Sampaio De Melo, Irini Sereti, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 2344.
https://doi.org/10.1182/blood-2025-2344
Published: 2025
Journal Articles

Survival after first relapse of pediatric B-ALL differs by insurance type: A real-world analysis from the recall-1 study

Free
Katherine Lind, Abigale Berry, Yimei Li, Hongyan Liu, Jeremy Rubinstein, Gabriella Nguyen, Vanessa Fabrizio, Anurekha Hall, Deepa Bhojwani, Troy Quigg, Shannon Maude, Nirali Shah, Maria Ortega, Abdulla Al-Mulla, Ibrahim Ahmed, Jill Beck, Deepika Bhatla, Eliza Briscoe, Roland Chu, Laurie Davis, J. Gregory Dolan, Jennifer Drinkwine, Anna Elias, Lyannette Elo, Elizabeth Eom, Kelly Faulk, Erin Goode, Darcy Hamill, Miza Salim Hammoud, Ashley Hinson, Alex Hoover, Hannah Kinoshita, Mira Kohorst, Elizabeth Krieger, Cathy Lee-Miller, Kevin McNerney, Jordan Milner, Amy Moskop, Giselle Moore-Higgs, Lindsey Murphy, Megan Murphy, Hiren Patel, Thomas Pfeiffer, Alexandra Prosser-Dombrowski, Mahvish Rahim, April Rahrig, Amanda Saraf, Jamie Shoag, Heather Symons, Nicholas Tastet, Stephanie Thomas, Molly Thornock, Keri Toner, Smitha Vasanna, Alejandra Escobar Vasco, Allison Weisnicht, Sara Zarnegar-Lumley, Lena Winestone, Regina Myers, Caitlin Elgarten
Journal: Blood
Blood (2025) 146 (Supplement 1): 6292.
https://doi.org/10.1182/blood-2025-6292
Published: 2025
Journal Articles

Tali-cel is a safe and effective therapy in patients with Relapsed/Refractory B-cell non-Hodgkin lymphoma that allows equitable access- a real-world experience from India.

Free
Hasmukh Jain, Atharva Karulkar, Devanshi Kalra, Smrithi Ravikumar, Anand Vaibhaw, Shreshtha Shah, Afrin Firfiray, Juber Pendhari, Sameer Melinkeri, Rahul Bhargava, Neeraj Siddarthan, Dr Dinesh Bhurani, Jayachandran P.K., Esha Kaul, Prashant Mehta, Hari Menon, Bhausaheb Bagal, Kunal Goyal, Prakash Shekhawat, Pavan Kumar Boyella, Rakesh Boya, Ram Abhinav, Rayaz Ahmed, Anil Aribandi, Ashwin V Nair, Chandran Nair, Harish Palaparthi, Lingaraj Nayak, Pawan Singh, Priyanshi Pachauri, Rajat Bhattacharya, Rajiv Kumar, Ranjit Sahoo, Sharat Damodar, Vikram Mathews, Vasu Babu Goli, Abhishek Charan, Ajay Gupta, Amul Kapoor, Anupam Chakrapani, Ashish Bakshi, Bijay Prabhakaran Nair, Bilal Kazi, Debranjani Chattopadhyay, Ganesh S. Jaishetwar, Kaushal Kalra, Kishore Kumar, Lekshmon K.S, Madhav Danthala, Mallikarjun Kalashetty, Narendra Anukonda, Naveen Gupta, Nivedita Dhingra, Padmaja Lokireddy, Prasad Narayanan, Parathan Karunakaran, Prasanth Ganesan, Punit Jain, Priyanka Samal, Ramaswamy N.V., Rajan Kapoor, Shyam Aggarwal, Roy J Palatty, Sainath Bhethanabhotla, Sachin Almel, Santhosh Devadas, Sivakumaran Janakiraman, Sudeep V, Sreeraj Vasudevan, Sameer Tulpule, Suraj Chiraniya, Vijay Patil, Sumita Chaudhry, T Raja, Sunu Cyriac, Shishir Seth, Chezhian Subash, Varun Rajan, Alok Shetty, Vishwanath Sathyanarayanan, Mohammed Sadique Ansari, Nishant Tiwari, Shamil Darbar, Supriya Chawkekar, Sushmita Sahay, Manivasagam Sundharam, Ashish Saroha, Moumita Basu, Anjali Jaiswal, Yuktam Yadav, Sakshi Soni, Jayashree Thorat, Shalini Purwar, Nirali Shah, Terry Fry, Nitin Jain, Sattva Neelapu, Manju Sengar, Rahul Purwar
Journal: Blood
Blood (2025) 146 (Supplement 1): 6288.
https://doi.org/10.1182/blood-2025-6288
Published: 2025
Journal Articles

Transplantation for children with acute myeloid leukemia: a comparison of outcomes with reduced intensity and myeloablative regimens

Free
Menachem Bitan, Wensheng He, Mei-Jie Zhang, Hisham Abdel-Azim, Mouhab Fakhreddine Ayas, Bella Bielorai, Paul A. Carpenter, Mitchell S. Cairo, Miguel Angel Diaz, John T. Horan, Sonata Jodele, Carrie L. Kitko, Kirk R. Schultz, Morris Kletzel, Kimberly A. Kasow, Leslie E. Lehmann, Parinda A. Mehta, Nirali Shah, Michael A. Pulsipher, Tim Prestidge, Adriana Seber, Shalini Shenoy, Ann E. Woolfrey, Lolie C. Yu, Stella M. Davies
Journal: Blood
Blood (2014) 123 (10): 1615–1620.
https://doi.org/10.1182/blood-2013-10-535716
Published: 2014