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Journal Articles

A Decade of Ibrutinib for CLL with and without TP53 Aberration: Final Report on an Investigator-Sponsored Phase 2 Study

Andy Itsara, Victoria M. Rogness, Laura Samples, Constance M. Yuan, Hao-Wei Wang, Inhye E. Ahn, Mohammed Z.H. Farooqui, Xin Tian, Clare Sun, Emily Tomasulo, Susan Soto, Jeanine Superata, Larisa Bezkorovaynaya, Thomas E. Hughes, Pia K. Nierman, Adrian Wiestner

Blood blood.2025029971.

https://doi.org/10.1182/blood.2025029971

Published: 2025

Includes: Supplemental data

Journal Articles

Gene expression profiling reveals two overarching types of ALCL with distinct targetable biology: an LLMPP study

Andrew L. Feldman, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Naoki Oishi, Guangzhen Hu, Pedro Farinha, Catalina Amador, Elías Campo, Wing C. Chan, James R. Cook, Jan Delabie, Kai Fu, Timothy C Greiner, Laura K Hilton, Giorgio GA Inghirami, Javeed Iqbal, Elaine S Jaffe, Ryan Morin, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Philipp W Raess, Andreas Rosenwald, Kerry J. Savage, Graham W. Slack, Susan L. Slager, Joo Y Song, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A Wilcox, xueju wang, Min Shi, Akira Satou, Anamarija M Perry, Roberto Nicolas Miranda, L.Jeffrey Jeffrey Medeiros, Matthew J Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S Kahl, Liuyan Jiang, David L Jaye, Alejandro Gru, Laurence L de Leval, Weina Chen, Jennifer R. Chapman, James R Cerhan, Carlos Barrionuevo, Stephen M. Ansell, Ahmed Aljudi

Blood blood.2024027700.

https://doi.org/10.1182/blood.2024027700

Published: 2025

Includes: Supplemental data

Journal Articles

CRLF2-rearrangement and extramedullary disease in B-cell acute lymphoblastic leukemia: A possible link?

Flavia Mesquita Gava, Bonnie Yates, Grace Li, Chelsea O'Koren, Biplov Adhikari, Haneen Shalabi, Evrim Turkbey, Constance Yuan, Hao-Wei Wang, Sara Silbert, Nirali Shah

Blood (2025) 146 (Supplement 1): 5099.

https://doi.org/10.1182/blood-2025-5099

Published: 2025

Journal Articles

Evaluating flow cytometry (FC) and next generation sequencing (NGS) for assessing minimal residual disease (MRD) and B-cell aplasia (BCA) in children, adolescents and young adults (CAYA) with B-cell acute lymphoblastic leukemia (B-ALL)

Chelsea O'Koren, Julie Ma, Bonnie Yates, Hao-Wei Wang, Constance Yuan, Chloe Hoang, Tanvi Verma, David Peske, Ilan Kirsch, Challice Bonifant, Nirali Shah

Blood (2025) 146 (Supplement 1): 3363.

https://doi.org/10.1182/blood-2025-3363

Published: 2025

Journal Articles

CD19/22 CAR T-cells in children and young adults with B-ALL: Final Phase 1 trial results

Sara Silbert, Flavia Gava, Bonnie Yates, Alexander Rankin, Lauren Little, Toni Foley, Alexandra Dreyzin, Christopher Chien, Naomi Taylor, Terry Fry, Constance Yuan, Hao-Wei Wang, David Stroncek, Steven Highfill, Haneen Shalabi, Nirali Shah

Blood (2025) 146 (Supplement 1): 814.

https://doi.org/10.1182/blood-2025-814

Published: 2025

Journal Articles

Phase 2 trial of cladribine plus immediate rituximab for 1st-line treatment of hairy cell leukemia – long term follow-up of original and additional patient cohorts

Robert Kreitman, Hao-Wei Wang, Dana Delgado Colon, Evgeny Arons, Hong Zhou, Mark Raffeld, Liqiang Xi, Julie Feurtado, Lacey James, Katherine Calvo, Irina Maric, Constance Yuan

Blood (2025) 146 (Supplement 1): 3609.

https://doi.org/10.1182/blood-2025-3609

Published: 2025

Journal Articles

Phase 2 trial of encorafenib plus binimetinib for patients with BRAF V600 mutated relapsed/refractory hairy cell leukemia

Robert Kreitman, Hao-Wei Wang, Dana Delgado Colon, Evgeny Arons, Hong Zhou, Mark Raffeld, Liqiang Xi, Eager Holly, Lacey James, Katherine Calvo, Irina Maric, Constance Yuan

Blood (2025) 146 (Supplement 1): 5683.

https://doi.org/10.1182/blood-2025-5683

Published: 2025

Journal Articles

MAP2K1 and MAP2K2 genes alterations in hairy cell leukemia and hairy cell leukemia variant.

Evgeny Arons, Tai Chin-Hsein, Liu Yuelin, Chi-Ping Day, Christopher Oakes, Seema Bhat, Michael Grever, Kerry Rogers, Mark Raffeld, Liqiang Xi, Hong Zhou, Mory Gould, Arieh Fischthal, Isaac Shpilman, Hao-Wei Wang, Constance Yuan, Cenk Sahinalp, Robert Kreitman

Blood (2025) 146 (Supplement 1): 3532.

https://doi.org/10.1182/blood-2025-3532

Published: 2025

Journal Articles

Phase 2 trial of rituximab with either pentostatin or bendamustine for multiply relapsed or refractory hairy cell leukemia

Brett Schroeder, Constance M. Yuan, Hao-Wei Wang, Chirayu Mohindroo, Hong Zhou, Mark Raffeld, Liqiang Xi, Evgeny Arons, Julie Catherine Feurtado, Lacey James-Echenique, Katherine R Calvo, Irina Maric, Robert J. Kreitman

Blood blood.2025031243.

https://doi.org/10.1182/blood.2025031243

Published: 2025

Includes: Supplemental data

Journal Articles

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Sara K. Silbert, Alexander W. Rankin, Chloe N. Hoang, Alexandra Semchenkova, Regina M. Myers, Elena Zerkalenkova, Hao-Wei Wang, Alexandra E. Kovach, Constance M. Yuan, Dana Delgado Colon, Loïc Vasseur, Alex Bataller, Samuel John, Kaylyn Utley Lyons, Barbara Friedes, Anna Alonso-Saladrigues, Hisham Abdel-Azim, Estelle Balducci, Ahmed Assim Aljudi, Marie Balsat, D. Nathan Biery, Aghiad Chamdin, Bill H. Chang, Raymund S. Cuevo, Barbara De Moerloose, David S. Dickens, Ulrich Duffner, Nicolas Duployez, Firas El Chaer, Michelle Ann Elliott, Gabriele Escherich, Sneha Fernandes, Mandi R. Fitzjohn, Zhubin Gahvari, Stephan A. Grupp, Rui Rochelle He, Cynthia Harrison, Christopher B. Hergott, Emily M. Hsieh, Annette S. Kim, Dennis J. Kuo, Daniel P. Larson, Benjamin J. Lee, Thibaut Leguay, R. Coleman Lindsley, Abhishek A. Mangaonkar, Kerstin Mezger, Holly L. Pacenta, Jing Pan, Marlie Provost, Latika Puri, Sunil S. Raikar, Armando Martinez, Isabella Bristol, Kyle Murphy, Lauren Reiman, Michele Redell, Kelly Reed, Gabrielle Roth-Guepin, Jeremy Rubinstein, Süreyya Savaşan, Kristian Schafernak, Alexandra Stevens, Aimee Talleur, Naomi Torres Carapia, Jacques Vargaftig, Anant Vatsayan, Matthias Wölfl, Liping Zhao, Susana Rives, Vanessa A. Fabrizio, Koji Sasaki, Ibrahim Aldoss, Nicolas Boissel, Susan R. Rheingold, Kara L. Davis, Sara Ghorashian, Elad Jacoby, Alexander Popov, Adam J. Lamble, Nirali N. Shah

Blood (2025) 146 (4): 437–455.

https://doi.org/10.1182/blood.2024026655

Published: 2025

Includes: Supplemental data

Journal Articles

Non-V600E BRAF mutations and treatment for hairy cell leukemia

Evgeny Arons, Chin-Hsien Tai, Joshi Suraj, Yuelin Liu, Chi-Ping Day, Mark Raffeld, Liqiang Xi, Hong Zhou, Mory Gould, Isaac Shpilman, Cristopher C. Oakes, Seema Bhat, Michael Grever, Daniel Jones, Kerry Rogers, Hao-Wei Wang, Constance M. Yuan, Cenk Sahinalp, Robert J. Kreitman

Blood (2025) 145 (17): 1957–1961.

https://doi.org/10.1182/blood.2024026894

Published: 2025

Includes: Supplemental data

Journal Articles

Rituximab Reduces Immunogenicity and Increases Complete Remissions without Minimal Residual Disease in Relapsed/Refractory Hairy Cell Leukemia Patients Receiving Moxetumomab Pasudotox

Robert J. Kreitman, Constance M. Yuan, Hao-Wei Wang, Hong Zhou, Mark Raffeld, Liqiang Xi, Evgeny Arons, Julie Feurtado, Lacey James, Raul C. Braylan, Katherine R. Calvo, Irina Maric, Ira Pastan

Blood (2024) 144 (Supplement 1): 6791.

https://doi.org/10.1182/blood-2024-199569

Published: 2024

Journal Articles

Non-V600E BRAF Gene Alterations in Hairy Cell Leukemia

Evgeny Arons, Chin-Hsien Tai, Suraj Joshi, Yuelin Liu, Chi-ping Day, Mark Raffeld, Liqiang Xi, Hong Zhou, Mory Gould, Isaac Shpilman, Christopher C. Oakes, Seema A Bhat, Michael R. Grever, Kerry A. Rogers, Hao-Wei Wang, Constance M. Yuan, Cenk Sahinalp, Robert J. Kreitman

Blood (2024) 144 (Supplement 1): 1586.

https://doi.org/10.1182/blood-2024-204016

Published: 2024

Journal Articles

A Phase 2 Response-Adapted Study of Daratumumab, Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple Myeloma

Blood (2024) 144 (Supplement 1): 7059.

https://doi.org/10.1182/blood-2024-201563

Published: 2024

Journal Articles

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Andrew L. Feldman, Guangzhen Hu, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Jimena B. Gimenez, Farah M. Salama, Min Shi, Elías Campo, Wing Chung Chan, James R. Cook, Giorgio Inghirami, Elaine S. Jaffe, Ryan Morin, Phillipp W. Raess, Andreas Rosenwald, Kerry J. Savage, Louis M. Staudt, George W. Wright, Catalina Amador, Jan Delabie, Timothy C. Greiner, Javeed Iqbal, Laura K. Hilton, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Graham W. Slack, Susan L. Slager, Joo Y. Song, Hao-Wei Wang, Ahmed A. Aljudi, Stephen M. Ansell, Carlos Barrionuevo, James R. Cerhan, Jennifer R. Chapman-Fredricks, Weina Chen, Laurence de Leval, Alejandro A. Gru, David L. Jaye, Liuyan Jiang, Brad S. Kahl, Kennosuke Karube, Young Hyeh Ko, Eric Mou, Matthew J. Maurer, L. Jeffrey Medeiros, Roberto N. Miranda, Naoki Oishi, Perry M. Anamarija, Akira Satou, Xueju Wang, Ryan A. Wilcox, Xiaojun Wu, Tadashi Yoshino, Yu Zeng

Blood (2024) 144 (Supplement 1): 2974.

https://doi.org/10.1182/blood-2024-202410

Published: 2024

Journal Articles

Initial Experience with CD19/CD22 BiCistronic CAR T-Cells in Children and Young Adults with Recurrent or Refractory B-Cell Malignancies

Brynn B. Duncan, Sara K. Silbert, Alexander W. Rankin, Bonnie Yates, Lauren Little, Toni Foley, Hao-Wei Wang, Constance M. Yuan, Dana I. Delgado Colon, Yanyu Wang, Jon Inglefield, John A Ligon, Hannah W. Song, Steven L. Highfill, Haneen Shalabi, David F. Stroncek, Naomi Taylor, Nirali N. Shah

Blood (2024) 144 (Supplement 1): 680.

https://doi.org/10.1182/blood-2024-198259

Published: 2024

Journal Articles

A Randomized Phase 2 Trial of 2nd-Line Cladribine with Concurrent or Delayed Rituximab in Patients with Classic Hairy Cell Leukemia

Robert J. Kreitman, Hao-Wei Wang, Dana I. Delgado Colon, Hong Zhou, Evgeny Arons, Mark Raffeld, Liqiang Xi, Julie Feurtado, Lacey James, Raul C. Braylan, Katherine R. Calvo, Irina Maric, Constance M. Yuan

Blood (2024) 144 (Supplement 1): 863.

https://doi.org/10.1182/blood-2024-202793

Published: 2024

Journal Articles

Monocytic Differentiation in B-Lymphoblastic Leukemia with CRLF2 rearrangement at Diagnosis: Implications for Pathogenesis and Post-Therapeutic Lineage Switch

Alexandra E. Kovach, Sara K. Silbert, Annie Luong, Gerald Lu, Michael Lu, Hao-Wei Wang, Karen M Chisholm, Andrew Doan, Deepa Bhojwani, Adam Lamble, Nirali N. Shah, Chintan Parekh, Gordana Raca, Brent L. Wood

Blood (2024) 144 (Supplement 1): 2799.

https://doi.org/10.1182/blood-2024-198961

Published: 2024

Journal Articles

Long-Term Outcomes in Chronic Lymphocytic Leukemia Treated with Ibrutinib: 10-Year Follow-up of a Phase 2 Study

Andy Itsara, Clare Sun, Emily Bryer, Inhye E Ahn, Susan Soto, Hao-Wei Wang, Constance M. Yuan, Adrian Wiestner

Blood (2023) 142 (Supplement 1): 201.

https://doi.org/10.1182/blood-2023-182397

Published: 2023

Journal Articles

Gene Expression Profiling Reveals Two Overarching Types of Anaplastic Large Cell Lymphoma with Distinct Targetable Biology: An L.L.M.P.P. Study

Blood (2023) 142 (Supplement 1): 847.

https://doi.org/10.1182/blood-2023-186969

Published: 2023

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A Decade of Ibrutinib for CLL with and without TP53 Aberration: Final Report on an Investigator-Sponsored Phase 2 Study

Gene expression profiling reveals two overarching types of ALCL with distinct targetable biology: an LLMPP study

CRLF2-rearrangement and extramedullary disease in B-cell acute lymphoblastic leukemia: A possible link?

Evaluating flow cytometry (FC) and next generation sequencing (NGS) for assessing minimal residual disease (MRD) and B-cell aplasia (BCA) in children, adolescents and young adults (CAYA) with B-cell acute lymphoblastic leukemia (B-ALL)

CD19/22 CAR T-cells in children and young adults with B-ALL: Final Phase 1 trial results

Phase 2 trial of cladribine plus immediate rituximab for 1st-line treatment of hairy cell leukemia – long term follow-up of original and additional patient cohorts

Phase 2 trial of encorafenib plus binimetinib for patients with BRAF V600 mutated relapsed/refractory hairy cell leukemia

MAP2K1 and MAP2K2 genes alterations in hairy cell leukemia and hairy cell leukemia variant.

Phase 2 trial of rituximab with either pentostatin or bendamustine for multiply relapsed or refractory hairy cell leukemia

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Non-V600E BRAF mutations and treatment for hairy cell leukemia

Rituximab Reduces Immunogenicity and Increases Complete Remissions without Minimal Residual Disease in Relapsed/Refractory Hairy Cell Leukemia Patients Receiving Moxetumomab Pasudotox

Non-V600E BRAF Gene Alterations in Hairy Cell Leukemia

A Phase 2 Response-Adapted Study of Daratumumab, Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple Myeloma

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Initial Experience with CD19/CD22 BiCistronic CAR T-Cells in Children and Young Adults with Recurrent or Refractory B-Cell Malignancies

A Randomized Phase 2 Trial of 2nd-Line Cladribine with Concurrent or Delayed Rituximab in Patients with Classic Hairy Cell Leukemia

Monocytic Differentiation in B-Lymphoblastic Leukemia with CRLF2 rearrangement at Diagnosis: Implications for Pathogenesis and Post-Therapeutic Lineage Switch

Long-Term Outcomes in Chronic Lymphocytic Leukemia Treated with Ibrutinib: 10-Year Follow-up of a Phase 2 Study

Gene Expression Profiling Reveals Two Overarching Types of Anaplastic Large Cell Lymphoma with Distinct Targetable Biology: An L.L.M.P.P. Study

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