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David F. Stroncek
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Journal Articles

Making Anti-CD19 CAR-T Cell Therapy Accessible and Affordable: First-in-Human Phase I Clinical Trial Experience from India

Atharva Karulkar, Hasmukh Jain, Shreshtha Shah, Aalia Khan, Ankesh Jaiswal, Afrin Firfiray, Prashant Suvasia, Priyanshi Suvasia, Juber Pendhari, Sweety Asija, Ambalika Chowdury, Ankit Banik, Smrithi Ravikumar, Neha Sharma, Minal Poojary, Sumathi Hiregoudar, Preeti Desai, Anisha Navkudkar, Sunil Rajadhyaksha, Jayashree Thorat, Prashant R. Tembhare, Albeena Nisar, Manju Sengar, David F. Stroncek, Steven Highfill, Nirali N. Shah, Gaurav Narula, Rahul Purwar
Journal: Blood
Blood (2022) 140 (Supplement 1): 4610–4611.
https://doi.org/10.1182/blood-2022-168928
Published: 2022
Journal Articles

Transient Responses and Significant Toxicities Due to Cytopenias and Rashes with Anti-CD30 CAR T Cells for CD30-Expressing Lymphomas: Results of a Phase I Clinical Trial

Jennifer N. Brudno, Jeremiah Karrs, Danielle Natrakul, Nisha Patel, Lekha Mikkilineni, Jennifer Mann, David F. Stroncek, Steven Highfill, Norris Lam, Genevieve C. Fromm, Rashmika Patel, Stefania Pittaluga, James N. Kochenderfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 12731–12732.
https://doi.org/10.1182/blood-2022-157149
Published: 2022
Journal Articles

Allogeneic Peripheral Blood Stem Cell Transplantation for Bone Marrow Failure Syndromes Using CD34 + -Selected Progenitor Cells Co-Infused with a Reduced Number of Non-Mobilized T-Cells

Georg Aue, Yazan Migdady, Yimo Wang, Jennifer Wilder, Brian Wells, Rosa Nadal Rios, Joseph A. Clara, Robert Reger, Kristen Gunn, Melissa Spencer, Jennifer Farren, Patricia Prince, Reem A Shalabi, Steven Highfill, David F. Stroncek, Xin Tian, Richard W. Childs
Journal: Blood
Blood (2022) 140 (Supplement 1): 7576–7577.
https://doi.org/10.1182/blood-2022-169922
Published: 2022
Journal Articles

Extended Detection in Peripheral Blood Following Infusion of Chronic Granulomatous Disease Patient Autologous Granulocytes Corrected By mRNA Transfection in Patients with Chronic Granulomatous Disease

Vera Bzhilyanskaya, Ronald J. Meis, Narda Theobald, Tyra Estwick, Hong Lei, Steven Highfill, David F. Stroncek, Leonard Chen, Kamille West-Mitchell, Gary A. Dahl, Harry L Malech, Suk See De Ravin, Julie Brault
Journal: Blood
Blood (2022) 140 (Supplement 1): 5475–5476.
https://doi.org/10.1182/blood-2022-170390
Published: 2022
Journal Articles

T Cells Expressing a Fully-Human Anti-BCMA Chimeric Antigen Receptor with a Heavy-Chain-Only Antigen-Recognition Domain Exhibit Rapid and Durable Activity Against Multiple Myeloma

Lekha Mikkilineni, Elisabet E. Manasanch, Danielle Natrakul, Katherine Weissler, Jennifer N. Brudno, Jennifer Mann, Stephanie L Goff, James C Yang, Norris Lam, Irina Maric, Hao-Wei Wang, Constance M. Yuan, David F. Stroncek, Steven Highfill, Micaela Ganadan, Rashmika Patel, Steven A Rosenberg, James N. Kochenderfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 7433–7434.
https://doi.org/10.1182/blood-2022-159156
Published: 2022
Journal Articles

Characterization of HLH-like manifestations as a CRS variant in patients receiving CD22 CAR T cells

Clinical Trials & Observations
Daniel A. Lichtenstein, Fiorella Schischlik, Lipei Shao, Seth M. Steinberg, Bonnie Yates, Hao-Wei Wang, Yanyu Wang, Jon Inglefield, Alina Dulau-Florea, Francesco Ceppi, Leandro C. Hermida, Kate Stringaris, Kim Dunham, Philip Homan, Parthav Jailwala, Justin Mirazee, Welles Robinson, Karen M. Chisholm, Constance Yuan, Maryalice Stetler-Stevenson, Amanda K. Ombrello, Jianjian Jin, Terry J. Fry, Naomi Taylor, Steven L. Highfill, Ping Jin, Rebecca A. Gardner, Haneen Shalabi, Eytan Ruppin, David F. Stroncek, Nirali N. Shah
Journal: Blood
Blood (2021) 138 (24): 2469–2484.
https://doi.org/10.1182/blood.2021011898
Published: 2021
Includes: Supplemental data
Journal Articles

Optimization of Autologous Hematopoietic Progenitor Stem Cell Apheresis Collection from Plerixafor-Mobilized Patients with Sickle Cell Disease

Yan Zheng, Akshay Sharma, Alexis Leonard, Kamille West, Naoya Uchida, Shuyu E, Lilora Kearney, Cortina Williams, Kirsten Hartwell, Regina Bosnick, Sandhya R. Panch, David F. Stroncek, Leigh Poston, Salem M. Akel, Neha Gupta, Jane S Hankins, Courtney D. Fitzhugh, Matthew Hsieh, John F. Tisdale, Mitchell J. Weiss
Journal: Blood
Blood (2021) 138 (Supplement 1): 1770.
https://doi.org/10.1182/blood-2021-146669
Published: 2021
Journal Articles

Longitudinal Transcriptional Analysis of Peripheral Blood Leukocytes in COVID Convalescent Donors

Mallikarjuna Rao Gedda, Patrick Danaher, Lipei Shao, Martin Ongkeko, Leonard Chen, Mame Thioye Sall, Opal Reddy, Christina Bailey, Amy Wahba, Inna Dzekunova, Valeria De Giorgi, Robert Somerville, Jin Ping, Kamille West, Sandhya R. Panch, David F. Stroncek
Journal: Blood
Blood (2021) 138 (Supplement 1): 1767.
https://doi.org/10.1182/blood-2021-152645
Published: 2021
Journal Articles

Treatment of Patients with T Cells Expressing a Fully-Human Anti-BCMA CAR with a Heavy-Chain Antigen-Recognition Domain Caused High Rates of Sustained Complete Responses and Relatively Mild Toxicity

Lekha Mikkilineni, Elisabet E. Manasanch, Danielle Natrakul, Jennifer N. Brudno, Jennifer Mann, Stephanie L Goff, James C Yang, Norris Lam, Irina Maric, Maryalice Stetler-Stevenson, Hao-Wei Wang, Constance M. Yuan, Tyler Lowe, David F. Stroncek, Steven Highfill, Rashmika Patel, Micaela Ganadan, Steven A Rosenberg, James N. Kochenderfer
Journal: Blood
Blood (2021) 138 (Supplement 1): 3837.
https://doi.org/10.1182/blood-2021-152688
Published: 2021
Journal Articles

Changes in Quality-of-Life Parameters in Patients Receiving Therapeutic Interventions for Cancer-Associated Anemia: A Systematic Review

Snigdha Marivada, Sandhya R. Panch, Kamyab Pirouz, Chhaya Kamwal, Alexandra Dreyzin, Alicia Livinski, David F. Stroncek, Xiaobai Li, Barbara Bryant
Journal: Blood
Blood (2021) 138 (Supplement 1): 2142.
https://doi.org/10.1182/blood-2021-152843
Published: 2021
Journal Articles

Deep and Durable Remissions of Relapsed Multiple Myeloma on a First-in-Humans Clinical Trial of T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor (CAR) with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain

Lekha Mikkilineni, MD, Elisabet E. Manasanch, MD, Danielle Vanasse, BS, Jennifer N. Brudno, MD, Jennifer Mann, CRNP, Richard Sherry, MD, Stephanie L Goff, MD, James C Yang, MD, Norris Lam, BS, Irina Maric, MD MSci, Maryalice Stetler-Stevenson, MD PhD, Hao-Wei Wang, MD PhD, Constance M. Yuan, MD PhD, David F. Stroncek, MD, Steven L Highfill, PhD, Vicki Fellowes, Micaela Ganadan, BSN, RN, Rashmika Patel, Steven A Rosenberg, MD PhD, James N. Kochenderfer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
https://doi.org/10.1182/blood-2020-138839
Published: 2020
Journal Articles

Cell Density of NK Cells during Ex Vivo Expansion Impacts NK Cell Surface TRAIL Expression

Joseph A. Clara, MD, Robert Reger, MS, Mala Chakraborty, PhD, Steven L Highfill, PhD, Jianjian Jin, PhD, David F. Stroncek, MD, Richard W. Childs, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-141487
Published: 2020
Journal Articles

Rapid Engraftment, Immune Recovery, and Resolution of Transfusion Dependence in Treatment-Refractory Severe Aplastic Anemia Following Transplantation with Ex Vivo Expanded Umbilical Cord Blood (Omidubicel)

Mohamed Samour, MD, Georg Aue, MD PhD, Joseph Clara, Jennifer Wilder, Robert Reger, MS, Rosa Nadal Rios, MD, Kate Stringaris, MD PhD, Brian Wells, Lisa Cook, Kristen Gunn, Reem A Shalabi, PharmD, Josef Rivero, Patricia Prince, David F. Stroncek, MD, Willy A. Flegel, MD, Xin Tian, PhD, Richard W. Childs, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-137771
Published: 2020
Journal Articles

Lower Hematopoietic Progenitor Cell Counts and Yields at Subsequent Donations Is Influenced By a Shorter Inter-Donation Interval between the First and Subsequent Mobilizations

Sandhya R. Panch, MDMPH, Brent R. Logan, Jennifer A. Sees, MPH, Bipin N. Savani, MD, Nirali N. Shah, MD, Jack W. Hsu, MD, Michael A. Pulsipher, MD, Galen E. Switzer, PhD, Bronwen E. Shaw, MD PhD, David F. Stroncek, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1962.
https://doi.org/10.1182/blood-2019-123492
Published: 2019
Journal Articles

Safe and Efficient Peripheral Blood Stem Cell Collection in Patients with Sickle Cell Disease Using Plerixafor

Alexis Leonard, MD, Naoya Uchida, MD, David F. Stroncek, MD, Sandhya R. Panch, MDMPH, Kamille West, Eoghan George Molloy, MD, Tom Hughes, Pharm.D., Sara Hauffe, RN, Tiffani Taylor, Courtney D. Fitzhugh, MD, Jane S. Hankins, MD MS, Megan Wilson, MSW, CCRP, Akshay Sharma, MBBS, Shengdar Q. Tsai, PhD, Mitchell J. Weiss, MD, PhD, Matthew Hsieh, MD, John F. Tisdale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1964.
https://doi.org/10.1182/blood-2019-126091
Published: 2019
Journal Articles

T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain Induce Remissions in Patients with Relapsed Multiple Myeloma

Lekha Mikkilineni, MD, Elisabet E. Manasanch, MD, Norris Lam, BS, Danielle Vanasse, BS, Jennifer N. Brudno, MD, Irina Maric, MD MSci, Jeremy J. Rose, MS, Maryalice Stetler-Stevenson, MD PhD, Hao-Wei Wang, MD PhD, Constance M. Yuan, MD PhD, David F. Stroncek, MD, Jennifer Mann, CRNP, Micaela Ganadan, BSN, RN, Rashmika Patel, Nathan Trinklein, PhD, Ben Buelow, MD PhD, Ronald E. Gress, MD, James N. Kochenderfer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3230.
https://doi.org/10.1182/blood-2019-129088
Published: 2019
Journal Articles

Developing the Next Generation of iPSC Cell-Based Immunotherapies

Raul Vizcardo, PhD, Nicholas Donald Klemen, MD, Rafiqul Islam, PhD, Devikala Gurusamy, PhD, Naritaka Tamaoki, MD, PhD, Li Jia, PhD, Zhiya Yu, PhD, Amanda N Hennings, PhD, Takuya Maeda, MD, Marta Bosch-Marce, PhD, Meghan L Good, MD, Svetlana Pack, PhD, David F. Stroncek, Francis A Flomerfelt, PhD, Michael J Kruhlak, PhD, Nicholas Phillip Restifo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3707.
https://doi.org/10.1182/blood-2018-99-118593
Published: 2018
Journal Articles

Robust Cell Selections and Depletions across Various Hematopoietic Cell Fractions on the Clinimacs Plus Instrument

Thejaswi Bikkani, MBBS, Katherine Li, Anusha Rao, Angela Pickett, Xiaobai Li, PhD, Minoo Battiwalla, MD, Richard W. Childs, MD, John Barrett, MD, Andre Larochelle, MD PhD, Elizabeth Kang, MD, David F. Stroncek, Sandhya R. Panch, MD MPH
Journal: Blood
Blood (2018) 132 (Supplement 1): 3818.
https://doi.org/10.1182/blood-2018-99-118582
Published: 2018
Journal Articles

Low Levels of Neurologic Toxicity with Retained Anti-Lymphoma Activity in a Phase I Clinical Trial of T Cells Expressing a Novel Anti-CD19 CAR

Jennifer Brudno, MD, Steven Hartman, Norris Lam, BS, David F. Stroncek, John M. Rossi, MS, Yueh-wei Shen, Allen Xue, PhD, Adrian Bot, MD PhD, Jennifer A Kanakry, MD, Steven Z. Pavletic, MD, Lekha Mikkilineni, MD, Mark Roschewski, MD, Robert M. Dean, MD, Jeremy J. Rose, MS, Rashmika Patel, Brenna Hansen, Steve A. Rosenberg, Ronald E. Gress, MD, James N. Kochenderfer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 697.
https://doi.org/10.1182/blood-2018-99-113731
Published: 2018
Journal Articles

Abbreviated T-Cell Activation on the Automated Clinimacs Prodigy Device Enhances Bispecific CD19/22 Chimeric Antigen Receptor T-Cell Viability and Fold Expansion, Reducing Total Culture Duration

Sandeep K Srivastava, PhD, Sandhya R. Panch, MD MPH, Jianjian Jin, PhD, Haneen Shalabi, DO, Nirali N. Shah, MD, Steven L Highfill, PhD, David F. Stroncek
Journal: Blood
Blood (2018) 132 (Supplement 1): 4551.
https://doi.org/10.1182/blood-2018-99-116846
Published: 2018