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Journal Articles

Project Evolve, Evaluation of Lineage Switch (LS), an International Initiative: Preliminary Results Reveal Dismal Outcomes in Patients with LS

Sara K. Silbert, Cynthia Harrison, D. Nathan Biery, Alexandra Semchenkova, Elena Zerkalenkova, Anna Alonso-Saladrigues, Kaylyn Utley, Ibrahim Aldoss, Liping Zhao, Sneha Fernandes, Jeremy D. Rubinstein, Naomi Torres Carapia, Bill H. Chang, Anant Vatsayan, Barbara De Moerloose, Holly L. Pacenta, Dennis John Kuo, Gabriele Escherich, Benjamin J. Lee, Michele S. Redell, Mandi R. Fitzjohn, Daniel P. Larson, Nicolas Duployez, Raymund S. Cuevo, Rui Rochelle He, David Dickens, Firas El Chaer, Kelly Reed, Matthias Wolfl, Sunil S. Raikar, Süreyya Savaşan, Latika Puri, Zhubin J. Gahvari, Aimee C. Talleur, Hisham Abdel-Azim, Aghiad Chamdin, Marlie R.M. Provost, Vanessa A. Fabrizio, Kerstin Mezger, Alexandra McLean Stevens, Emily M. Hsieh, Hao-Wei Wang, Constance M. Yuan, Ulrich A. Duffner, Jing Pan, Sara Ghorashian, Susana Rives, Chloe Hoang, Kara L. Davis, Elad Jacoby, Alexander Popov, Adam Lamble, Nirali N. Shah

Blood (2023) 142 (Supplement 1): 4202.

https://doi.org/10.1182/blood-2023-182293

Published: 2023

Journal Articles

Prior Knowledge Integration Improves Relapse Prediction and Identifies Relapse Associated Mechanisms in Childhood B Cell Acute Lymphoblastic Leukemia

Abhishek Vallabhbhai Koladiya, Astraea Jager, Anthony Culos, Milton Merchant, Yuxuan Liu, Lucille Stuani, Jolanda Sarno, Pablo Domizi, Charles G. Mullighan, Nima Aghaeepour, Sean Bendall, Kara L. Davis

Blood (2023) 142 (Supplement 1): 1603.

https://doi.org/10.1182/blood-2023-187264

Published: 2023

Journal Articles

Enrichment in Metabolic Pathway Activation Corresponds to Immunoglobulin Gene Diversity across B Cell Developmental Stages in B-Lymphoblastic Leukemia

Carol Fries Simpson, Yuxuan Liu, Lucille Stuani, Astraea Jager, Cameron Baker, Diana G. Adlowitz, Philip J Rock, Richard Burack, Kara L. Davis

Blood (2023) 142 (Supplement 1): 2972.

https://doi.org/10.1182/blood-2023-189313

Published: 2023

Journal Articles

Uridine Synthesis Is the Metabolic Vulnerability in Relapse-Associated B-ALL Cells with Active Pre-BCR Signaling

Yuxuan Liu, Haowen Jiang, Lucille Stuani, Jolanda Sarno, Pablo Domizi, Milton Merchant, Dorra Jedoui, Astraea Jager, Min Huang, Norman J. Lacayo, Kathleen M. Sakamoto, Jiangbin Ye, Kara L. Davis

Blood (2023) 142 (Supplement 1): 4340.

https://doi.org/10.1182/blood-2023-186925

Published: 2023

Journal Articles

CD22 CAR T Cell-Related IEC-HS Is Associated with an IFN-γ Cytokine Signature

Hrishikesh Srinagesh, John H. Baird, Neha Agarwal, Yi-Jiun Su, Anne Marijn Kramer, Agnes Reschke, Nikeshan Jeyakumar, Sushma Bharadwaj, Liora Michal Schultz, Sneha Ramakrishna, Kara L. Davis, Bita Sahaf, Steven Feldman, Crystal L. Mackall, David B. Miklos, Lori S. Muffly, Matthew J. Frank

Blood (2023) 142 (Supplement 1): 4839.

https://doi.org/10.1182/blood-2023-178283

Published: 2023

Journal Articles

Single-Cell Proteomic Analysis Defines Metabolic Heterogeneity in Response to Venetoclax in AML

Lucille Stuani, Astraea Jager, Ambrine Sahal, Abhishek Koladiya, Jolanda Sarno, Pablo Domizi, Yuxuan Liu, Veronique De Mas, Christian Recher, Francois Vergez, Jean-Emmanuel Sarry, Kara L. Davis

Blood (2022) 140 (Supplement 1): 1028–1029.

https://doi.org/10.1182/blood-2022-171009

Published: 2022

Journal Articles

Improved Relapse Prediction in Pediatric Acute Myeloid Leukemia By Deconvolving Lineage-Specific and Cancer-Specific Features in Single-Cell Data

Timothy James Keyes, Astraea Jager, Michael Krueger, Sylvia Plevritis, Robert Tibshirani, Richard Aplenc, Garry P. Nolan, Michele S. Redell, Kara L. Davis

Blood (2022) 140 (Supplement 1): 6288–6289.

https://doi.org/10.1182/blood-2022-170939

Published: 2022

Journal Articles

Proof of Principle for Intracarotid Injection of Leukemia As Model for Late Stage Central Nervous System Leukemia

Crystal Wang, Adrian Rodrigues, Sophia Chernikova, Kara L. Davis, Melanie Hayden Gephart

Blood (2022) 140 (Supplement 1): 11522–11523.

https://doi.org/10.1182/blood-2022-158294

Published: 2022

Journal Articles

CD22 CAR T Cells Demonstrate Favorable Safety Profile and High Response Rates in Pediatric and Adult B-ALL: Results of a Phase 1b Study

Nikeshan Jeyakumar, Sneha Ramakrishna, Matthew J Frank, Bita Sahaf, Steven A. Feldman, David B. Miklos, Crystal L. Mackall, Kara L. Davis, Lori Muffly, Liora M. Schultz

Blood (2022) 140 (Supplement 1): 2374–2375.

https://doi.org/10.1182/blood-2022-164456

Published: 2022

Journal Articles

Long-Term Follow-up of CD19/22 CAR Therapy in Children and Young Adults with B-ALL Reveals Efficacy, Tolerability and High Survival Rates When Coupled with Hematopoietic Stem Cell Transplantation

Blood (2022) 140 (Supplement 1): 10300–10302.

https://doi.org/10.1182/blood-2022-167789

Published: 2022

Journal Articles

Plasma Microbial Cell-Free DNA to Characterize Infection Vs Cytokine Release Syndrome in Pediatric Patients with B ALL after CAR T Cell Therapy

Catherine Aftandilian, Xue Rachel Bito, David M. Berman, Radha Duttagupta, Kara L. Davis

Blood (2022) 140 (Supplement 1): 4681–4683.

https://doi.org/10.1182/blood-2022-163662

Published: 2022

Journal Articles

Chromatin Content Capture Reveals Acute Leukaemia Oncogenic Vulnerability Point in Human B Cell Development

Reema Baskar, Patricia Favaro, Warren D. Reynolds, Pablo Domizi, Albert G Tsai, Kara L. Davis, Sean Bendall

Blood (2021) 138 (Supplement 1): 673.

https://doi.org/10.1182/blood-2021-153114

Published: 2021

Journal Articles

CD22-CAR T-Cell Therapy Mediates High Durable Remission Rates in Adults with Large B-Cell Lymphoma Who Have Relapsed after CD19-CAR T-Cell Therapy

Blood (2021) 138 (Supplement 1): 741.

https://doi.org/10.1182/blood-2021-152145

Published: 2021

Journal Articles

Ikaros Mediates Antigen Escape Following CD19 CAR T Cell Therapy in r/r B-ALL

Pablo Domizi, Jolanda Sarno, Astraea Jager, Reema Baskar, Warren D. Reynolds, Bita Sahaf, Sean Bendall, Charles G. Mullighan, Allison Barz Leahy, Regina M. Myers, Stephan A. Grupp, Elena Sotillo, David Barrett, Kara L. Davis

Blood (2021) 138 (Supplement 1): 613.

https://doi.org/10.1182/blood-2021-151002

Published: 2021

Journal Articles

Glucocorticoid-Resistant B-Cell Acute Lymphoblastic Leukemic Cells Can be Targeted By BCR-Signaling Inhibition

Jolanda Sarno, Pablo Domizi, Yuxuan Liu, Milton Merchant, Dorra Jedoui, Astraea Jager, Andrea Biondi, Giuseppe Gaipa, Alessio Felice Bava, Kara L. Davis

Blood (2021) 138 (Supplement 1): 617.

https://doi.org/10.1182/blood-2021-150356

Published: 2021

Journal Articles

Inhibition of Pre-BCR Signaling Mediates a Metabolic Switch in B-Cell Progenitor Acute Lymphoblastic Leukemia

Yuxuan Liu, Lucille Stuani, Dorra Jedoui, Milton Merchant, Astraea Jager, Jolanda Sarno, Charles G. Mullighan, Felix J. Hartmann, Sean Bendall, Kara L. Davis

Blood (2021) 138 (Supplement 1): 615.

https://doi.org/10.1182/blood-2021-145956

Published: 2021

Journal Articles

Gene Expression Analysis of CML Patients across the Age Spectrum

Blood (2021) 138 (Supplement 1): 1473.

https://doi.org/10.1182/blood-2021-148701

Published: 2021

Journal Articles

CD22-directed CAR T-cell therapy induces complete remissions in CD19-directed CAR–refractory large B-cell lymphoma

Blood (2021) 137 (17): 2321–2325.

https://doi.org/10.1182/blood.2020009432

Published: 2021

Includes: Supplemental data

Journal Articles

HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia

Michael W Boyer, MD, Sonali Chaudhury, MBBS,MD, Kara L Davis, DO, Timothy Alan Driscoll, MD, Stephan A Grupp, MD PhD, Michelle Hermiston, MD PhD, Samuel John, MD, Amy K Keating, MD PhD, Christina Kovacs, BS, JD, Andrea Magley, BS, Gary Douglas Myers, MD, Christine L Phillips, MD, Michael A Pulsipher, MD, Das Purkayastha, PhD, Julie-An Talano, MD, Jennifer Willert, MD

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-136340

Published: 2020

Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142270

Published: 2020

NARROW

Project Evolve, Evaluation of Lineage Switch (LS), an International Initiative: Preliminary Results Reveal Dismal Outcomes in Patients with LS

Prior Knowledge Integration Improves Relapse Prediction and Identifies Relapse Associated Mechanisms in Childhood B Cell Acute Lymphoblastic Leukemia

Enrichment in Metabolic Pathway Activation Corresponds to Immunoglobulin Gene Diversity across B Cell Developmental Stages in B-Lymphoblastic Leukemia

Uridine Synthesis Is the Metabolic Vulnerability in Relapse-Associated B-ALL Cells with Active Pre-BCR Signaling

CD22 CAR T Cell-Related IEC-HS Is Associated with an IFN-γ Cytokine Signature

Single-Cell Proteomic Analysis Defines Metabolic Heterogeneity in Response to Venetoclax in AML

Improved Relapse Prediction in Pediatric Acute Myeloid Leukemia By Deconvolving Lineage-Specific and Cancer-Specific Features in Single-Cell Data

Proof of Principle for Intracarotid Injection of Leukemia As Model for Late Stage Central Nervous System Leukemia

CD22 CAR T Cells Demonstrate Favorable Safety Profile and High Response Rates in Pediatric and Adult B-ALL: Results of a Phase 1b Study

Long-Term Follow-up of CD19/22 CAR Therapy in Children and Young Adults with B-ALL Reveals Efficacy, Tolerability and High Survival Rates When Coupled with Hematopoietic Stem Cell Transplantation

Plasma Microbial Cell-Free DNA to Characterize Infection Vs Cytokine Release Syndrome in Pediatric Patients with B ALL after CAR T Cell Therapy

Chromatin Content Capture Reveals Acute Leukaemia Oncogenic Vulnerability Point in Human B Cell Development

CD22-CAR T-Cell Therapy Mediates High Durable Remission Rates in Adults with Large B-Cell Lymphoma Who Have Relapsed after CD19-CAR T-Cell Therapy

Ikaros Mediates Antigen Escape Following CD19 CAR T Cell Therapy in r/r B-ALL

Glucocorticoid-Resistant B-Cell Acute Lymphoblastic Leukemic Cells Can be Targeted By BCR-Signaling Inhibition

Inhibition of Pre-BCR Signaling Mediates a Metabolic Switch in B-Cell Progenitor Acute Lymphoblastic Leukemia

Gene Expression Analysis of CML Patients across the Age Spectrum

CD22-directed CAR T-cell therapy induces complete remissions in CD19-directed CAR–refractory large B-cell lymphoma

HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

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American Society of Hematology

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American Society of Hematology

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