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Sharon Mavroukakis
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Journal Articles

Overlap of post-CAR T HLH toxicity definitions and their prognostic significance in children and young adults with B-acute lymphoblastic leukemia

Free
Kevin McNerney, Soyang Kwon, Swati Naik, Vanessa Fabrizio, Gabriela Llaurador Caraballo, Lazaro Sanchez-Pinto, Aimee Talleur, Xiaopei Lily Zeng, Christina Baggott, Anant Vatsayan, Michael Verneris, Snehit Prabhu, Jenna Rossoff, Holly Pacenta, Christine Phillips, Julie-An Talano, Amy Moskop, Douglas Myers, Nicole Karras, Challice Bonifant, Muna Qayed, Prakash Satwani, William Temple, Christa Krupski, Amy Keating, Susanne Baumeister, Emily Egeler, Sharon Mavroukakis, Kevin Curran, Crystal Mackall, Theodore Laetsch, Rebecca Gardner, Liora Schultz
Journal: Blood
Blood (2025) 146 (Supplement 1): 4501.
https://doi.org/10.1182/blood-2025-4501
Published: 2025
Journal Articles

Sequential CD19 and CD22 CART for relapsed and refractory B cell ALL: Phase I results

Free
Liora Schultz, Catherine Aftandilian, Christina Baggott, Nicole Corwin, Michelle Fujimoto, Amy Li, Sharon Mavroukakis, Jennifer Moon, Bita Sahaf, Ashley Jacobs, Emily DeYager, Cristina Mendoza, Andrea Levenson, Matthew Frank, David Miklos, Lori Muffly, Steven Feldman, Janette Alcazar, Ramya Tunuguntla, Annie Brown, Raya Saab, Jay Balagtas, Tanja Gruber, Pablo Domizi, Sneha Ramakrishna, Crystal Mackall, Kara Davis
Journal: Blood
Blood (2025) 146 (Supplement 1): 2374.
https://doi.org/10.1182/blood-2025-2374
Published: 2025
Journal Articles

CD22-directed CAR-T cells induce complete remissions in high-risk follicular and Mantle Cell Lymphoma with limited neurotoxicity

Free
Hrishikesh Srinagesh, Anne Marijn Kramer, Mark Hamilton, Yi-Jiun Su, Kendall Kozy, LaTesha Jackson, Annie Brown, Kimi DeNoble, Sharon Mavroukakis, Claire Lohman, Kristen Cunanan, Neha Agarwal, Sushma Bharadwaj, Warren Reynolds, Sally Arai, Laura Johnston, Robert Lowsky, Everett Meyer, Robert Negrin, Andrew Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa Kennedy, Melody Smith, Saurabh Dahiya, Kara Davis, Sneha Ramakrishna, Liora Schultz, Ramya Tunuguntla, Lori Muffly, Crystal Mackall, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 4159.
https://doi.org/10.1182/blood-2025-4159
Published: 2025
Journal Articles

Role of B Cell Recovery in Relapse Risk and CD19 Phenotype Following Real-World Use of Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia: A Multi-Institutional Retrospective Study

Free
Xiaopei Lily Zeng, Soyang Kwon, Anant Vatsayan, Christina Baggott, Snehit Prabhu, Samuel John, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas D. Myers, Erin Marie Hall, Nicole A Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K Keating, Susanne H.C. Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Khanh Nguyen, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Kevin O. McNerney
Journal: Blood
Blood (2024) 144 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2024-211231
Published: 2024
Journal Articles

CD22-Directed CAR T-Cell Therapy Achieves Complete Remission in CD19-Directed CAR T-Cell Refractory Follicular and Mantle Cell Lymphoma

Free
Anne Marijn Kramer, Hrishikesh Srinagesh, Yi-Jiun Su, Mark P. Hamilton, Kendall Levine, Eleonora Migliore, Kimi DeNoble, Annie K. Brown, Kristen Cunanan, Neha Agarwal, Claire Lohman, Sharon Mavroukakis, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Saurabh Dahiya, Kara L. Davis, Sneha Ramakrishna, Liora Michal Schultz, Ramya Tunuguntla, Steven A. Feldman, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2024) 144 (Supplement 1): 2064.
https://doi.org/10.1182/blood-2024-198489
Published: 2024
Journal Articles

CD22-Directed CAR T-Cell Therapy for Large B-Cell Lymphomas Progressing after CD19-Directed CAR T-Cell Therapy: Continued Durable Remissions at 3-Year Follow-up

Free
Anne Marijn Kramer, John H. Baird, Hrishikesh Srinagesh, Emily Egeler, Kendall Levine, Annie K. Brown, Sharon Mavroukakis, Kristen Cunanan, Yi-Jiun Su, Neha Agarwal, Mark P. Hamilton, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Saurabh Dahiya, Kara L. Davis, Sneha Ramakrishna, Liora Michal Schultz, Ramya Tunuguntla, Steven A. Feldman, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2024) 144 (Supplement 1): 69.
https://doi.org/10.1182/blood-2024-198544
Published: 2024
Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Free
Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

Long-Term Follow-up of CD19/22 CAR Therapy in Children and Young Adults with B-ALL Reveals Efficacy, Tolerability and High Survival Rates When Coupled with Hematopoietic Stem Cell Transplantation

Free
Liora M. Schultz, Sneha Ramakrishna, Reema Baskar, Rebecca M Richards, Jennifer Moon, Christina Baggott, Michelle Fujimoto, Michael Kunicki, Amy Li, Sneha Jariwala, Courtney Erickson, Ashley Jacobs, Karen Yamabe, Valentin Barsan, Robbie G. Majzner, Emily L. Egeler, Sharon Mavroukakis, Zachary Ehlinger, Warren D. Reynolds, Bita Sahaf, Lori Muffly, Matthew J Frank, Anne-Louise Gramstrup, Harshini Chinnasamy, Shabnum Patel, David B. Miklos, Steven A. Feldman, Crystal L. Mackall, Kara L. Davis
Journal: Blood
Blood (2022) 140 (Supplement 1): 10300–10302.
https://doi.org/10.1182/blood-2022-167789
Published: 2022
Journal Articles

Phase I Trial Using CD19/CD22 Bispecific CAR T Cells in Pediatric and Adult Acute Lymphoblastic Leukemia (ALL)

Free
Liora M Schultz, MD, Lori S Muffly, MD, Jay Y. Spiegel, MDFRCPC, Sneha Ramakrishna, MD, Nasheed Hossain, MD, Christina Baggott, RN, PhD, Bita Sahaf, PhD, Shabnum Patel, PhD, Juliana Craig, BA, Jenny Yoon, Meena Kadapakkam, MD, Robbie G. Majzner, MD, Matthew J. Frank, MD PhD, Courtney Erickson, Anne Cunniffe Marcy, MSBH, Michelle Fujimoto, Neehar Bhatia, Everett H Meyer, MD PhD, Katherine A. Kong, Emily Egeler, Sharon Mavroukakis, Haiying Qin, MS, Terry J. Fry, MD, Steven A Feldman, PhD, David B Miklos, MD PhD, Crystal L. Mackall, MD, Kara L. Davis, DO
Journal: Blood
Blood (2019) 134 (Supplement_1): 744.
https://doi.org/10.1182/blood-2019-129411
Published: 2019
Journal Articles

Phase 1 Study of CD19/CD22 Bispecific Chimeric Antigen Receptor (CAR) Therapy in Children and Young Adults with B Cell Acute Lymphoblastic Leukemia (ALL)

Free
Liora M Schultz, MD, Kara L. Davis, DO, Christina Baggott, RN, PhD, Christie Chaudry, NP, Anne Cunniffe Marcy, MSBH, Sharon Mavroukakis, Bita Sahaf, PhD, Katherine A Kong, Lori S Muffly, MD, Stephen Kim, Everett H Meyer, MD PhD, Terry J. Fry, MD, Haiying Qin, MS, David B. Miklos, MD PhD, Crystal L. Mackall, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 898.
https://doi.org/10.1182/blood-2018-99-117445
Published: 2018
Journal Articles

Phase I Experience with a Bi-Specific CAR Targeting CD19 and CD22 in Adults with B-Cell Malignancies

Free
Nasheed Hossain, MD, Bita Sahaf, PhD, Matthew Abramian, PhD, Jay Y. Spiegel, MD, Katie Kong, Stephen Kim, Sharon Mavroukakis, Jean Oak, MD PhD, Yasodha Natkunam, MD PhD, Everett H Meyer, MD PhD, Matthew J. Frank, MD PhD, Steven A Feldman, PhD, Steven R. Long, MD, Haiying Qin, MS, Terry J. Fry, MD, Lori S Muffly, MD, Crystal L. Mackall, MD, David B. Miklos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 490.
https://doi.org/10.1182/blood-2018-99-110142
Published: 2018