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Lori Muffly
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Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

How I use next-generation sequencing–MRD to plan approach and prevent relapse after HCT for children and adults with ALL

Lori Muffly, Emily C. Liang, J. Gregory Dolan, Michael A. Pulsipher
Journal: Blood
Blood (2024) 144 (3): 253–261.
https://doi.org/10.1182/blood.2023023699
Published: 2024
Journal Articles

Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease and Toxicity

Caspian Oliai, Rasmus T Hoeg, Anna Pavlova, Arpita Gandhi, Lori Muffly, Rohtesh S. Mehta, Samer A Srour, Edmund K. Waller, Robert Lowsky, Sagar S. Patel, Bhagirathbhai Dholaria, Carlos Bachier, Jeremy M. Pantin, Amandeep Salhotra, Joseph P. McGuirk, Nathaniel B Fernhoff, J Scott McClellan, Mehrdad Abedi, Robert S. Negrin, Everett H Meyer
Journal: Blood
Blood (2022) 140 (Supplement 1): 654–656.
https://doi.org/10.1182/blood-2022-165654
Published: 2022
Journal Articles

Geographical Barriers to Accessing Specialty Cancer Care Among Adolescents and Young Adults with Acute Lymphoblastic Leukemia

Lori Muffly, Ariadna Garcia, Katharine Miller, Theresa H.M. Keegan, Helen Parsons
Journal: Blood
Blood (2022) 140 (Supplement 1): 2402–2403.
https://doi.org/10.1182/blood-2022-163840
Published: 2022
Journal Articles

Belumosudil Combination Therapy in Refractory Chronic Graft-Versus-Host Disease

Michelle Chin, Judith A. Shizuru, Lori Muffly, Parveen Shiraz, Laura J. Johnston, Robert Lowsky, Andrew R. Rezvani, Matthew J. Frank, Sushma Bharadwaj, Wen-Kai Weng, Robert S. Negrin, David B. Miklos, Sally Arai
Journal: Blood
Blood (2022) 140 (Supplement 1): 4788–4789.
https://doi.org/10.1182/blood-2022-165547
Published: 2022
Journal Articles

Ultra-Sensitive Next-Generation Sequencing Establishes the Prognostic Value of Very Low MRD in Adults with Acute Lymphoblastic Leukemia Undergoing Hematopoietic Cell Transplantation

Emily C. Liang, Simone E. Dekker, Jean M.G. Sabile, Stefan Torelli, Amy Zhang, Katharine Miller, Parveen Shiraz, Brandon Hayes-Lattin, Jessica Leonard, Lori Muffly
Journal: Blood
Blood (2022) 140 (Supplement 1): 1732–1733.
https://doi.org/10.1182/blood-2022-157442
Published: 2022
Journal Articles

Subsequent Solid Neoplasms Following Hematopoietic Cell Transplantation (HCT) for Hematologic Malignancies: Comparing Center for International Blood and Marrow Transplant Research (CIBMTR) and California Cancer Registry (CCR) Data

Sara J. Schonfeld, Bryan Valcarcel, Christa L. Meyer, Ann M Brunson, Julianne J.P. Cooley, Renata Abrahao, Ted Wun, Jeffery Auletta, Lori Muffly, Theresa H.M. Keegan, Lindsay M. Morton
Journal: Blood
Blood (2022) 140 (Supplement 1): 7670–7671.
https://doi.org/10.1182/blood-2022-159010
Published: 2022
Journal Articles

Comparison of Vital Status and Cause-Specific Mortality after Hematopoietic Cell Transplantation between the Center for International Blood and Marrow Transplant Research and the California Cancer Registry: A Record-Linkage Analysis from 1991 to 2018

Bryan Valcarcel, Sara J. Schonfeld, Christa L. Meyer, Ann M Brunson, Julianne J.P. Cooley, Renata Abrahao, Ted Wun, Jeffery Auletta, Lori Muffly, Theresa H.M. Keegan, Lindsay M. Morton
Journal: Blood
Blood (2022) 140 (Supplement 1): 7684–7685.
https://doi.org/10.1182/blood-2022-160330
Published: 2022
Journal Articles

The Development of Carhlh after Axicabtagene Ciloleucel Is Associated with Poor Outcomes

Shona Philip, Hrishikesh K. Srinagesh, Mark P Hamilton, Cesar Gentille, Alain Mina, Sally Arai, Laura J. Johnston, Robert Lowsky, Everett H Meyer, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Judith A Shizuru, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Saurabh Dahiya, Lori Muffly, Melody Smith, David B. Miklos, Matthew J Frank
Journal: Blood
Blood (2022) 140 (Supplement 1): 12775–12777.
https://doi.org/10.1182/blood-2022-170877
Published: 2022
Journal Articles

Utilization of Autologous HCT in Multiple Myeloma: A Novel Linkage of CIBMTR, Cancer Registry and Hospitalization Data in California

Naseem S Esteghamat, Ann M Brunson, Ted Wun, Aaron S Rosenberg, Julianne J.P. Cooley, Sara J. Schonfeld, Christa L. Meyer, Bryan Valcarcel, Renata Abrahao, Jeffery Auletta, Lindsay M. Morton, Lori Muffly, Theresa H.M. Keegan
Journal: Blood
Blood (2022) 140 (Supplement 1): 10060–10062.
https://doi.org/10.1182/blood-2022-159776
Published: 2022
Journal Articles

CD22 CAR T Cells Demonstrate Favorable Safety Profile and High Response Rates in Pediatric and Adult B-ALL: Results of a Phase 1b Study

Nikeshan Jeyakumar, Sneha Ramakrishna, Matthew J Frank, Bita Sahaf, Steven A. Feldman, David B. Miklos, Crystal L. Mackall, Kara L. Davis, Lori Muffly, Liora M. Schultz
Journal: Blood
Blood (2022) 140 (Supplement 1): 2374–2375.
https://doi.org/10.1182/blood-2022-164456
Published: 2022
Journal Articles

Interim Update on the 'Watch' Registry, a Real-World Observational Study Using Clonoseq® to Monitor MRD in Lymphoid Malignancies

Krish Patel, Jakub Svoboda, Bijal D. Shah, Bruce D. Cheson, Georges Azzi, Kashyap Patel, Andrew J Cowan, Lori Muffly, Heidi Simmons, Mark Schliekelman, Jessica Leonard
Journal: Blood
Blood (2022) 140 (Supplement 1): 5192–5194.
https://doi.org/10.1182/blood-2022-167669
Published: 2022
Journal Articles

Long-Term Follow-up of CD19/22 CAR Therapy in Children and Young Adults with B-ALL Reveals Efficacy, Tolerability and High Survival Rates When Coupled with Hematopoietic Stem Cell Transplantation

Liora M. Schultz, Sneha Ramakrishna, Reema Baskar, Rebecca M Richards, Jennifer Moon, Christina Baggott, Michelle Fujimoto, Michael Kunicki, Amy Li, Sneha Jariwala, Courtney Erickson, Ashley Jacobs, Karen Yamabe, Valentin Barsan, Robbie G. Majzner, Emily L. Egeler, Sharon Mavroukakis, Zachary Ehlinger, Warren D. Reynolds, Bita Sahaf, Lori Muffly, Matthew J Frank, Anne-Louise Gramstrup, Harshini Chinnasamy, Shabnum Patel, David B. Miklos, Steven A. Feldman, Crystal L. Mackall, Kara L. Davis
Journal: Blood
Blood (2022) 140 (Supplement 1): 10300–10302.
https://doi.org/10.1182/blood-2022-167789
Published: 2022
Journal Articles

Real World Outcomes in Acute Myeloid Leukemia Patients Following Post Hematopoietic Stem-Cell Transplantation Maintenance Treatment with Midostaurin or Sorafenib: A US Retrospective Cohort Study

Lori Muffly, Christopher Young, Bin Xie, Alana Block, Maelys Touya, Bhavik J. Pandya
Journal: Blood
Blood (2022) 140 (Supplement 1): 8111–8112.
https://doi.org/10.1182/blood-2022-157964
Published: 2022
Journal Articles

Analysis of Bendamustine Lymphodepletion, CD19 CART Expansion, Safety and Efficacy in Patients with Rel/Ref Non-Hodgkin Lymphoma

Sushma Bharadwaj, Mark P Hamilton, Bita Sahaf, John Tamaresis, Sunita Patil, Paul J Hanson, Theresa Latchford, Sally Arai, Laura J. Johnston, Robert Lowsky, Robert S. Negrin, Andrew R. Rezvani, Judith A Shizuru, Everett H Meyer, Parveen Shiraz, Surbhi Sidana, Melody Smith, Wen-Kai Weng, Lori Muffly, Crystal L. Mackall, Matthew J Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2022) 140 (Supplement 1): 10371–10373.
https://doi.org/10.1182/blood-2022-170759
Published: 2022
Journal Articles

Higher Rates of Severe Infection and Persistent Cytopenias in Long-Term CAR19 Responders Than after Autologous HCT: A Single Institution Study of 139 Subjects

Mark P Hamilton, Felicia C Liu-Fei, Stefan K. Alig, John Tamaresis, Mohammad Shahrokh Esfahani, Zinaida Good, Brian Sworder, Joseph Schroers-Martin, Chih Long Liu, Freja Tang Severinsen, Paul J Hanson, Ying Lu, Robert Lowsky, Robert S. Negrin, Everett H Meyer, Melody Smith, Sushma Bharadwaj, Judith A Shizuru, Surbhi Sidana, Parveen Shiraz, Andrew R. Rezvani, Laura J. Johnston, Wen-Kai Weng, Sally Arai, Lori Muffly, Saurabh Dahiya, Maximilian Diehn, David M. Kurtz, Bita Sahaf, Crystal L. Mackall, Matthew J Frank, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 7545–7547.
https://doi.org/10.1182/blood-2022-165600
Published: 2022
Journal Articles

Outcomes for Acute Myeloid Leukemia Relapse after Allogeneic Hematopoietic Cell Transplantation Remain Poor in the Modern Era

Shona Philip, Robert Lowsky, Laura J. Johnston, Sally Arai, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Judith A. Shizuru, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Matthew J. Frank, David B. Miklos, Melody Smith, Lori Muffly, Vaibhav Agrawal
Journal: Blood
Blood (2022) 140 (Supplement 1): 4825–4827.
https://doi.org/10.1182/blood-2022-168546
Published: 2022
Journal Articles

Measurable Residual Disease Status and FLT3 Inhibitor Therapy in Patients with FLT3-ITD Mutated AML Following Allogeneic Hematopoietic Cell Transplantation

Emily C. Liang, Connie Chen, Rong Lu, Gabriel N. Mannis, Lori Muffly
Journal: Blood
Blood (2021) 138 (Supplement 1): 1306.
https://doi.org/10.1182/blood-2021-149805
Published: 2021
Journal Articles

Outcomes for Myelofibrosis Patients Following Myeloablative Allogeneic Stem Cell Transplantation Using the Orca-T Graft from HLA-Matched Related and Unrelated Donors

Arpita Gandhi, Anna Moroz, Lori Muffly, Parveen Shiraz, Levanto Schachter, Nathaniel B Fernhoff, J Scott McClellan, Robert S. Negrin, Jason Gotlib, Everett H Meyer
Journal: Blood
Blood (2021) 138 (Supplement 1): 1819.
https://doi.org/10.1182/blood-2021-150521
Published: 2021
Journal Articles

Mgta-145 + Plerixafor Provides GCSF-Free Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study

Surbhi Sidana, Andriyana K Bankova, Hitomi Hosoya, Shaji Kumar, John Tamaresis, Anne Le, Lori Muffly, Laura J. Johnston, Sally Arai, Robert Lowsky, Everett H Meyer, Andrew R. Rezvani, Wen-Kai Weng, Matthew J. Frank, Parveen Shiraz, Douglas Girgenti, Kevin A. Goncalves, Veit Schmelmer, John C. Davis, Jr., Ying Lu, Judith A Shizuru, David B. Miklos
Journal: Blood
Blood (2021) 138 (Supplement 1): 3885.
https://doi.org/10.1182/blood-2021-149306
Published: 2021