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Zachary Ehlinger
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Journal Articles

Long-term Follow-up of Gastrointestinal CAR T-cell Lymphoma: Homing, Clonal Expansion, and Response to Cyclosporine

Available to Purchase
Hitomi Hosoya, Armando N Bastidas Torres, Sebastian Fernandez-Pol, John Mark Gubatan, Safa Najidh, George E Duran, Fei Dong, Zachary Ehlinger, Claire Lohman, Charles Wright, III, Bita Sahaf, Crystal L. Mackall, David B Miklos, Surbhi Sidana, David M Kurtz, Michael S Khodadoust, Lehka Mikkilineni
Journal: Blood
Blood blood.2025031423.
https://doi.org/10.1182/blood.2025031423
Published: 2025
Includes: Supplemental data
Journal Articles

CD22-CAR T cell multiomic features linked to patient outcomes in CD19-CAR resistant large B cell lymphoma

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Kameron Rodrigues, Mark Hamilton, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren Reynolds, Hrishikesh Srinagesh, Kristin Tsui, Skyler Rietberg, Kelvin Mo, John Baird, Yi-Jiun Su, Neha Agarwal, Elena Sotillo, Snehit Prabhu, Bita Sahaf, Saurabh Dahiya, Sneha Ramakrishna, Lori Muffly, Crystal Mackall, David Miklos, Zinaida Good, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 566.
https://doi.org/10.1182/blood-2025-566
Published: 2025
Journal Articles

Rapid peak CAR-T expansion is associated with delayed neurotoxicity following ciltacabtagene autoleucel in multiple myeloma

Free
Hitomi Hosoya, Arash Velayati, Danai Dima, Alexandria Jensen, Andrew Portuguese, Vanna Hovanky, Lekha Mikkilineni, Lauren Peres, Sylvester Homsy, Masooma Rana, Juancarlos Cancilla, Zachary Ehlinger, Bita Sahaf, Theresa Latchford, Ciara Louise Freeman, Omar Alexis Castaneda Puglianini, Saurabh Dahiya, Frederick Locke, David Miklos, Rahul Banerjee, Doris Hansen, Melissa Alsina, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 96.
https://doi.org/10.1182/blood-2025-96
Published: 2025
Journal Articles

Indolent CD8+ CAR T-Cell Lymphoma of the Gastrointestinal Tract after Ciltacabtagene Autoleucel Therapy for Relapsed/Refractory Multiple Myeloma

Free
Hitomi Hosoya, Sebastian Fernandez-Pol, John Gubatan, Zachary Ehlinger, Claire Lohman, Armando N Bastidas Torres, Safa Najidh, Alexa Kwang, George Duran, Charles Wright III, Vanessa E. Kennedy, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Matthew J. Frank, Lori Muffly, Wen-Kai Weng, Bita Sahaf, David Kurtz, Crystal L. Mackall, Michael S. Khodadoust, David B. Miklos, Surbhi Sidana, Lekha Mikkilineni
Journal: Blood
Blood (2024) 144 (Supplement 1): 4846.
https://doi.org/10.1182/blood-2024-207885
Published: 2024
Journal Articles

Safe and Effective Combination of Donor-Derived, Allogeneic CD19/CD22-CAR T Cells with Myeloablative Graft-Engineered Allo-HCT for High-Risk B-ALL

Free
Lori Muffly, Snegha Ananth, Lindsay Danley, Caroline Wagner, Diana Kordek, Kimi DeNoble, Ayesha Fraser, Emily Egeler, Alfonso Molina, Zachary Ehlinger, Moksha Desai, Hossein Daghagh, Ramya Tunuguntla, Annie K. Brown, Raquel Ibañez, Anne Marijn Kramer, Zinaida Good, Sally Arai, Laura Johnston, Robert Lowsky, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Sushma Bharadwaj, Saurabh Dahiya, Matthew J. Frank, Everett H. Meyer, Robert S. Negrin, Steven A. Feldman, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Melody Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 679.
https://doi.org/10.1182/blood-2024-211959
Published: 2024
Journal Articles

Single Institution Analysis of Lymphoma Treatment Related Post-CAR Myeloid Neoplasms

Free
Mark Hamilton, Nick Phillips, Dasom Lee, Zachary Ehlinger, Anne Marijn Kramer, Hrishikesh Srinagesh, Zinaida Good, Xiaoman Kang, Mari Olsen, Chih Long Liu, Feng Tian, Brian J. Sworder, Hitomi Hosoya, Joseph G. Schroers-Martin, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Lori Muffly, David Kurtz, Saurabh Dahiya, Matthew J. Frank, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 96.
https://doi.org/10.1182/blood-2024-205378
Published: 2024
Journal Articles

CD22-Directed CAR T Cell Single Cell Multiomic Features Associated with Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS)

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Hrishikesh Srinagesh, Mark P. Hamilton, Kelvin C. Mo, Snehit Prabhu, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren D. Reynolds, John H. Baird, Yi-Jiun Su, Neha Agarwal, Bita Sahaf, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank, Zinaida Good
Journal: Blood
Blood (2024) 144 (Supplement 1): 911.
https://doi.org/10.1182/blood-2024-198688
Published: 2024
Journal Articles

CCL8/CCL13-Producing Tumor-Associated Macrophages Linked to Poor Outcomes after CAR T Cell Therapy for LBCL

Free
Kelvin C. Mo, Christine Y. Yeh, Mark P. Hamilton, Jay Spiegel, Moksha Desai, Zachary Ehlinger, Warren D. Reynolds, Eric Yang, Michael G. Ozawa, Yiyun Chen, Snehit Prabhu, Matthew J. Frank, Lori Muffly, Gursharan K. Claire, Sushma Bharadwaj, Saurabh Dahiya, Katherine A. Kong, Elena Sotillo, Bita Sahaf, Sylvia Plevritis, David B. Miklos, Crystal L. Mackall, Zinaida Good
Journal: Blood
Blood (2024) 144 (Supplement 1): 368.
https://doi.org/10.1182/blood-2024-198942
Published: 2024
Journal Articles

Analysis of PET-CT Derived Radiomic Biomarkers with Efficacy, Safety, and Expansion of Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed or Refractory Large B-Cell Lymphoma (LBCL)

Free
Sushma Bharadwaj, Eric Lau, Ayesha Hashmi, Mark P. Hamilton, Alexandria Jensen, Anmol Goyal, Mallika Marar, Caroline Lee, Snegha Ananth, Bita Sahaf, Jayasindhu Mallampet, Zachary Ehlinger, Shriya Syal, Sunita Patil, Henry Guo, Melody Smith, Wen-Kai Weng, Matthew J. Frank, Michael S. Binkley, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2023) 142 (Supplement 1): 2125.
https://doi.org/10.1182/blood-2023-187617
Published: 2023
Journal Articles

CAR19 Therapy Drives Expansion of Clonal Hematopoiesis and Associated Cytopenias

Free
Mark P. Hamilton, Brian J. Sworder, Stefan K. Alig, Zinaida Good, Jan Boegeholz, Joseph Schroers-Martin, John Tamaresis, Mohammad Shahrokh Esfahani, Ying Lu, Mari Olsen, Chih Long Liu, Zachary Ehlinger, Moksha Desai, Felicia Liu-Fei, Lori S. Muffly, Robert S. Negrin, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Andrew R. Rezvani, Judith Shizuru, Wen-Kai Weng, Parveen Shiraz, Surbhi Sidana, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Bita Sahaf, Maximilian Diehn, Matthew J. Frank, Crystal L. Mackall, David M. Kurtz, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 360.
https://doi.org/10.1182/blood-2023-182522
Published: 2023
Journal Articles

Transcriptional Profiling Associated with CD22 CAR T Cell Clinical Response in LBCL

Free
Anne Marijn Kramer, Mark P. Hamilton, Snehit Prabhu, Moksha Desai, Adam Kuo, Zachary Ehlinger, Neha Agarwal, Yi-Jiun Su, Nikolaos Gkitsas, Carley Fowler, Vimal Keerthi, Aidan Retherford, Dorota Klysz, Ramya Tunuguntla, Steven Feldman, Bita Sahaf, John H. Baird, Lori S. Muffly, Crystal L. Mackall, David B. Miklos, Zinaida Good, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 2091.
https://doi.org/10.1182/blood-2023-187615
Published: 2023
Journal Articles

Long-Term Follow-up of CD19/22 CAR Therapy in Children and Young Adults with B-ALL Reveals Efficacy, Tolerability and High Survival Rates When Coupled with Hematopoietic Stem Cell Transplantation

Free
Liora M. Schultz, Sneha Ramakrishna, Reema Baskar, Rebecca M Richards, Jennifer Moon, Christina Baggott, Michelle Fujimoto, Michael Kunicki, Amy Li, Sneha Jariwala, Courtney Erickson, Ashley Jacobs, Karen Yamabe, Valentin Barsan, Robbie G. Majzner, Emily L. Egeler, Sharon Mavroukakis, Zachary Ehlinger, Warren D. Reynolds, Bita Sahaf, Lori Muffly, Matthew J Frank, Anne-Louise Gramstrup, Harshini Chinnasamy, Shabnum Patel, David B. Miklos, Steven A. Feldman, Crystal L. Mackall, Kara L. Davis
Journal: Blood
Blood (2022) 140 (Supplement 1): 10300–10302.
https://doi.org/10.1182/blood-2022-167789
Published: 2022
Journal Articles

CD22-CAR T-Cell Therapy Mediates High Durable Remission Rates in Adults with Large B-Cell Lymphoma Who Have Relapsed after CD19-CAR T-Cell Therapy

Free
Matthew J. Frank, John H. Baird, Shabnum Patel, Juliana Craig, Jay Y. Spiegel, Zachary Ehlinger, Harshini Chinnasamy, Sheren F. Younes, Jean S. Oak, Yasodha Natkunam, Warren D. Reynolds, Maria Iglesias, Emma Crawford, Hrishikesh K. Srinagesh, Emily L. Egeler, Sally Arai, Laura J. Johnston, Robert Lowsky, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Liora M. Schultz, Sneha Ramakrishna, Kara L. Davis, Bita Sahaf, Steven A. Feldman, Crystal L. Mackall, David B. Miklos, Lori Muffly
Journal: Blood
Blood (2021) 138 (Supplement 1): 741.
https://doi.org/10.1182/blood-2021-152145
Published: 2021
Journal Articles

CD22-directed CAR T-cell therapy induces complete remissions in CD19-directed CAR–refractory large B-cell lymphoma

Free
Clinical Trials & Observations Brief Report
John H. Baird, Matthew J. Frank, Juliana Craig, Shabnum Patel, Jay Y. Spiegel, Bita Sahaf, Jean S. Oak, Sheren F. Younes, Michael G. Ozawa, Eric Yang, Yasodha Natkunam, John Tamaresis, Zachary Ehlinger, Warren D. Reynolds, Sally Arai, Laura Johnston, Robert Lowsky, Everett Meyer, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Kara L. Davis, Sneha Ramakrishna, Liora Schultz, Chelsea Mullins, Allison Jacob, Ilan Kirsch, Steven A. Feldman, Crystal L. Mackall, David B. Miklos, Lori Muffly
Journal: Blood
Blood (2021) 137 (17): 2321–2325.
https://doi.org/10.1182/blood.2020009432
Published: 2021
Includes: Supplemental data
Journal Articles

CD22-Directed CAR T-Cell Therapy Mediates Durable Complete Responses in Adults with Relapsed or Refractory Large B-Cell Lymphoma after Failure of CD19-Directed CAR T-Cell Therapy and High Response Rates in Adults with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia

Free
John H. Baird, MD, Matthew J. Frank, MD PhD, Juliana Craig, BA, Shabnum Patel, PhD, Jay Y. Spiegel, MDFRCPC, Bita Sahaf, PhD, Sheren F. Younes, MD PhD, Jean S. Oak, MD PhD, Yasodha Natkunam, MD PhD, Zachary Ehlinger, MS, Warren D. Reynolds, BS, Sally Arai, MD MS, Laura J. Johnston, MD, Robert Lowsky, MD FRCP, Robert S. Negrin, MD, Andrew R. Rezvani, MD, Parveen Shiraz, MD, Surbhi Sidana, MD, Wen-Kai Weng, MD PhD, Liora M. Schultz, MD, Sneha Ramakrishna, MD, Kara L Davis, DO, Steven A. Feldman, PhD, Crystal L. Mackall, MD, David B. Miklos, MD PhD, Lori S. Muffly, MD MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-139087
Published: 2020