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Journal Articles

Long-term Follow-up of Gastrointestinal CAR T-cell Lymphoma: Homing, Clonal Expansion, and Response to Cyclosporine

Available to Purchase
Hitomi Hosoya, Armando N Bastidas Torres, Sebastian Fernandez-Pol, John Mark Gubatan, Safa Najidh, George E Duran, Fei Dong, Zachary Ehlinger, Claire Lohman, Charles Wright, III, Bita Sahaf, Crystal L. Mackall, David B Miklos, Surbhi Sidana, David M Kurtz, Michael S Khodadoust, Lehka Mikkilineni
Journal: Blood
Blood blood.2025031423.
https://doi.org/10.1182/blood.2025031423
Published: 2025
Includes: Supplemental data
Journal Articles

Superior efficacy and persistence of Orca-T-allogeneic CAR19/22 versus autologous CAR19/22 in high-risk adult B-ALL

Free
Alfonso Molina, Parveen Shiraz, Alyssa Kanegai, Ayesha Fraser, Diana Kordek, Caroline Wagner, Hrishikesh Srinagesh, Lindsay Danley, Arvind Ramakrishnan, Hossein Daghagh, Ying-Wen Huang, Gaurav Dhapola, Aman Siddiqui, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Vanessa Kennedy, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Wen-Kai Weng, Catherine McIntyre, Steven Feldman, Bita Sahaf, Crystal Mackall, David Miklos, Lori Muffly, Melody Smith
Journal: Blood
Blood (2025) 146 (Supplement 1): 514.
https://doi.org/10.1182/blood-2025-514
Published: 2025
Journal Articles

Rapid peak CAR-T expansion is associated with delayed neurotoxicity following ciltacabtagene autoleucel in multiple myeloma

Free
Hitomi Hosoya, Arash Velayati, Danai Dima, Alexandria Jensen, Andrew Portuguese, Vanna Hovanky, Lekha Mikkilineni, Lauren Peres, Sylvester Homsy, Masooma Rana, Juancarlos Cancilla, Zachary Ehlinger, Bita Sahaf, Theresa Latchford, Ciara Louise Freeman, Omar Alexis Castaneda Puglianini, Saurabh Dahiya, Frederick Locke, David Miklos, Rahul Banerjee, Doris Hansen, Melissa Alsina, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 96.
https://doi.org/10.1182/blood-2025-96
Published: 2025
Journal Articles

Redefining post-CD19 CAR T-cell surveillance with ctdna: Real-world insights from post- axi-cel and liso-cel therapy

Free
Snegha Ananth, Jayasindhu Mallampet, Betty Chang, Neha Agarwal, Katherine Kong, Bita Sahaf, Juan Carlos Suarez Serrato, Ilan Kirsch, Allison Jacob, Heidi Simmons, Lik Wee Lee, Crystal Mackall, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 941.
https://doi.org/10.1182/blood-2025-941
Published: 2025
Journal Articles

Double-dose axicabtagene ciloleucel (Axi-Cel-2) as second-line therapy for high-risk relapsed or refractory large B-cell lymphoma (r/rLBCL): Interim results from a Phase 1b study

Free
Dasom (Caroline) Lee, Kameron Rodrigues, Masooma Rana, Kendall Kozy, Sunny Salazar, Alexandria Jensen, Moksha Desai, Jayasindhu Mallampet, Claire Lohman, Ying-Wen Huang, Xiaoman Kang, Feng Tian, Jurik Mutter, Nick Phillips, Colleen Schweitzer, Faisal Cheema, Lekha Mikkilineni, Andrew Rezvani, Laura Johnston, Judith Shizuru, Everett Meyer, Robert Lowsky, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, Robert Negrin, Surbhi Sidana, Lori Muffly, Bita Sahaf, Yasodha Natkunam, Rhine Shen, Matthew Frank, Crystal Mackall, Zinaida Good, Ash Alizadeh, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 671.
https://doi.org/10.1182/blood-2025-671
Published: 2025
Journal Articles

Validated PET-CT metabolic tumor volume threshold identifies high-risk relapsed/refractory LBCL and predicts 12-month toxicity-free progression-free survival Post–CAR-T therapy

Free
Masooma Rana, Nima Ghalehsari, Alexandria Jensen, Dasom (Caroline) Lee, Natalie Park, Anmol Goyal, Ayesha Hashmi, William Wang, Eric Heng, Arash Velayati, Gaurav Dhapola, Ying-Wen Huang, Bita Sahaf, Wen-Kai Weng, Surbhi Sidana, Melody Smith, Sushma Bharadwaj, Matthew Frank, David Miklos, Michael Binkley, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 397.
https://doi.org/10.1182/blood-2025-397
Published: 2025
Journal Articles

Non-response to bridging therapy prior to CAR-T is associated with increased toxicity and adverse outcomes in Relapsed/Refractory multiple myeloma (RRMM)

Free
Masooma Rana, Alexandria Jensen, Arash Velayati, Vanna Hovanky, Lori Muffly, Bita Sahaf, David Iberri, Michaela Liedtke, Sushma Bharadwaj, Vanessa Kennedy, Sally Arai, Parveen Shiraz, Wen-Kai Weng, Melody Smith, Matthew Frank, David Miklos, Saurabh Dahiya, Hitomi Hosoya, Lekha Mikkilineni, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 4586.
https://doi.org/10.1182/blood-2025-4586
Published: 2025
Journal Articles

Sequential CD19 and CD22 CART for relapsed and refractory B cell ALL: Phase I results

Free
Liora Schultz, Catherine Aftandilian, Christina Baggott, Nicole Corwin, Michelle Fujimoto, Amy Li, Sharon Mavroukakis, Jennifer Moon, Bita Sahaf, Ashley Jacobs, Emily DeYager, Cristina Mendoza, Andrea Levenson, Matthew Frank, David Miklos, Lori Muffly, Steven Feldman, Janette Alcazar, Ramya Tunuguntla, Annie Brown, Raya Saab, Jay Balagtas, Tanja Gruber, Pablo Domizi, Sneha Ramakrishna, Crystal Mackall, Kara Davis
Journal: Blood
Blood (2025) 146 (Supplement 1): 2374.
https://doi.org/10.1182/blood-2025-2374
Published: 2025
Journal Articles

Evaluation of commercially available chimeric antigen receptor (CAR) detection reagents for monitoring of CAR T-cell (CAR T) expansion and persistence in patients (pts) treated with obecabtagene autoleucel (obe-cel)

Free
Rehan Hussain, Yousef Farag, Anish Patel, Hrishikesh Srinagesh, Lori Muffly, Bita Sahaf, David Miklos, Mathieu Ferrari, William Day, Pierre Lao-Sirieix
Journal: Blood
Blood (2025) 146 (Supplement 1): 2367.
https://doi.org/10.1182/blood-2025-2367
Published: 2025
Journal Articles

CD22-CAR T cell multiomic features linked to patient outcomes in CD19-CAR resistant large B cell lymphoma

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Kameron Rodrigues, Mark Hamilton, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren Reynolds, Hrishikesh Srinagesh, Kristin Tsui, Skyler Rietberg, Kelvin Mo, John Baird, Yi-Jiun Su, Neha Agarwal, Elena Sotillo, Snehit Prabhu, Bita Sahaf, Saurabh Dahiya, Sneha Ramakrishna, Lori Muffly, Crystal Mackall, David Miklos, Zinaida Good, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 566.
https://doi.org/10.1182/blood-2025-566
Published: 2025
Journal Articles

Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy in Octogenarian Patients (Aged ≥ 80) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Free
Dasom Lee, Sushma Bharadwaj, Masooma S Rana, Alexandria Jensen, William Wang, Nima Ghalehsari, Bita Sahaf, Jayasindhu Mallampet, Sarah Elkordy, Theresa Latchford, Sally Arai, Laura Johnston, Hitomi Hosoya, Robert Lowsky, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Everett H. Meyer, Parveen Shiraz, Lekha Mikkilineni, Wen-Kai Weng, Lauren S. Maeda, Melody Smith, Surbhi Sidana, Lori Muffly, Matthew J. Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2024) 144 (Supplement 1): 386.
https://doi.org/10.1182/blood-2024-201822
Published: 2024
Journal Articles

Anti-BCMA CAR T-Cell Expansion and Its Association with Response and Toxicity in Multiple Myeloma

Free
Hitomi Hosoya, Alexandria Jensen, Vanna Hovanky, Sylvester Homsy, Juancarlos E Cancilla, Sunita Patil, Vanessa E. Kennedy, Sushma Bharadwaj, Melody Smith, Parveen Shiraz, Matthew J. Frank, Saurabh Dahiya, Sally Arai, Wen-Kai Weng, Lori Muffly, Bita Sahaf, Crystal L. Mackall, David B. Miklos, Lekha Mikkilineni, Surbhi Sidana
Journal: Blood
Blood (2024) 144 (Supplement 1): 2006.
https://doi.org/10.1182/blood-2024-211128
Published: 2024
Journal Articles

Indolent CD8+ CAR T-Cell Lymphoma of the Gastrointestinal Tract after Ciltacabtagene Autoleucel Therapy for Relapsed/Refractory Multiple Myeloma

Free
Hitomi Hosoya, Sebastian Fernandez-Pol, John Gubatan, Zachary Ehlinger, Claire Lohman, Armando N Bastidas Torres, Safa Najidh, Alexa Kwang, George Duran, Charles Wright III, Vanessa E. Kennedy, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Matthew J. Frank, Lori Muffly, Wen-Kai Weng, Bita Sahaf, David Kurtz, Crystal L. Mackall, Michael S. Khodadoust, David B. Miklos, Surbhi Sidana, Lekha Mikkilineni
Journal: Blood
Blood (2024) 144 (Supplement 1): 4846.
https://doi.org/10.1182/blood-2024-207885
Published: 2024
Journal Articles

Safe and Effective Combination of Donor-Derived, Allogeneic CD19/CD22-CAR T Cells with Myeloablative Graft-Engineered Allo-HCT for High-Risk B-ALL

Free
Lori Muffly, Snegha Ananth, Lindsay Danley, Caroline Wagner, Diana Kordek, Kimi DeNoble, Ayesha Fraser, Emily Egeler, Alfonso Molina, Zachary Ehlinger, Moksha Desai, Hossein Daghagh, Ramya Tunuguntla, Annie K. Brown, Raquel Ibañez, Anne Marijn Kramer, Zinaida Good, Sally Arai, Laura Johnston, Robert Lowsky, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Sushma Bharadwaj, Saurabh Dahiya, Matthew J. Frank, Everett H. Meyer, Robert S. Negrin, Steven A. Feldman, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Melody Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 679.
https://doi.org/10.1182/blood-2024-211959
Published: 2024
Journal Articles

Single Institution Analysis of Lymphoma Treatment Related Post-CAR Myeloid Neoplasms

Free
Mark Hamilton, Nick Phillips, Dasom Lee, Zachary Ehlinger, Anne Marijn Kramer, Hrishikesh Srinagesh, Zinaida Good, Xiaoman Kang, Mari Olsen, Chih Long Liu, Feng Tian, Brian J. Sworder, Hitomi Hosoya, Joseph G. Schroers-Martin, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Lori Muffly, David Kurtz, Saurabh Dahiya, Matthew J. Frank, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 96.
https://doi.org/10.1182/blood-2024-205378
Published: 2024
Journal Articles

CD22-Directed CAR T Cell Single Cell Multiomic Features Associated with Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS)

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Hrishikesh Srinagesh, Mark P. Hamilton, Kelvin C. Mo, Snehit Prabhu, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren D. Reynolds, John H. Baird, Yi-Jiun Su, Neha Agarwal, Bita Sahaf, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank, Zinaida Good
Journal: Blood
Blood (2024) 144 (Supplement 1): 911.
https://doi.org/10.1182/blood-2024-198688
Published: 2024
Journal Articles

CCL8/CCL13-Producing Tumor-Associated Macrophages Linked to Poor Outcomes after CAR T Cell Therapy for LBCL

Free
Kelvin C. Mo, Christine Y. Yeh, Mark P. Hamilton, Jay Spiegel, Moksha Desai, Zachary Ehlinger, Warren D. Reynolds, Eric Yang, Michael G. Ozawa, Yiyun Chen, Snehit Prabhu, Matthew J. Frank, Lori Muffly, Gursharan K. Claire, Sushma Bharadwaj, Saurabh Dahiya, Katherine A. Kong, Elena Sotillo, Bita Sahaf, Sylvia Plevritis, David B. Miklos, Crystal L. Mackall, Zinaida Good
Journal: Blood
Blood (2024) 144 (Supplement 1): 368.
https://doi.org/10.1182/blood-2024-198942
Published: 2024
Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Free
Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

Long-Term Efficacy and Immune Reconstitution with Bendamustine As a Lymphodepleting Agent for Axicabtagene Ciloleucel (Axi-Cel) in Patients with Refractory or Relapsed Large B-Cell Lymphoma (LBCL)

Free
Sushma Bharadwaj, Eric Lau, Anmol Goyal, Mark P. Hamilton, Hrishikesh Srinagesh, Alexandria Jensen, Shriya Syal, Jayasindhu Mallampet, Theresa Latchford, Bita Sahaf, Wen-Kai Weng, Melody Smith, Holden T Maecker, Matthew J. Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2023) 142 (Supplement 1): 4878.
https://doi.org/10.1182/blood-2023-188166
Published: 2023
Journal Articles

Effective Prevention of Steroid-Requiring Chronic Graft-Vs.-Host Disease with B Cell Depletion: A Randomized, Placebo-Controlled Trial

Free
Corey Cutler, Haesook T. Kim, Hassan El Banna, Elizabeth Halloran, Emily Matozel, Vincent Ho, John Koreth, Mahasweta Gooptu, Roman M. Shapiro, Amar H Kelkar, Christopher James Gibson, Carol Reynolds, Michela Ansuinelli, Rayuko Tamada, Chloe Au, Zachariah Defilipp, Areej El-Jawahri, Yi-Bin Chen, Najla H El Jurdi, Daniel Weisdorf, Daniel R. Couriel, Catherine J. Lee, Bita Sahaf, Juliana Craig, Kathleen Ji, Robert J. Soiffer, David B. Miklos, Joseph Antin, Jerome Ritz
Journal: Blood
Blood (2023) 142 (Supplement 1): 649.
https://doi.org/10.1182/blood-2023-180142
Published: 2023