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Sushma Bharadwaj
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Journal Articles

Post-transplant cyclophosphamide vs tacrolimus/methotrexate: Improved GRFS, reduced NRM, and less severe GVHD in myeloablative HLA-matched allogeneic transplantation

Free
Alfonso Molina, Quenton Bubb, Ryan Yee, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Melody Smith, Wen-Kai Weng, David Miklos, Lori Muffly, Vanessa Kennedy
Journal: Blood
Blood (2025) 146 (Supplement 1): 2494.
https://doi.org/10.1182/blood-2025-2494
Published: 2025
Journal Articles

Superior efficacy and persistence of Orca-T-allogeneic CAR19/22 versus autologous CAR19/22 in high-risk adult B-ALL

Free
Alfonso Molina, Parveen Shiraz, Alyssa Kanegai, Ayesha Fraser, Diana Kordek, Caroline Wagner, Hrishikesh Srinagesh, Lindsay Danley, Arvind Ramakrishnan, Hossein Daghagh, Ying-Wen Huang, Gaurav Dhapola, Aman Siddiqui, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Vanessa Kennedy, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Wen-Kai Weng, Catherine McIntyre, Steven Feldman, Bita Sahaf, Crystal Mackall, David Miklos, Lori Muffly, Melody Smith
Journal: Blood
Blood (2025) 146 (Supplement 1): 514.
https://doi.org/10.1182/blood-2025-514
Published: 2025
Journal Articles

Allogeneic HSC and regulatory T cell  (Orca-T) engineered cell therapy following reduced intensity conditioning: Results of a single center Phase 1 study

Free
Alejandro Villar-Prados, Paige Kim, Katherine Sutherland, Robert Negrin, Sally Arai, Matthew Frank, Laura Johnston, Robert Lowsky, David Miklos, Lori Muffly, Saurabh Dahiya, Andrew Rezvani, Surbhi Sidana, Parveen Shiraz, Judith Shizuru, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, John Tamaresis, Anna Pavlova, J. Scott McClellan, Everett Meyer
Journal: Blood
Blood (2025) 146 (Supplement 1): 111.
https://doi.org/10.1182/blood-2025-111
Published: 2025
Journal Articles

Patients with TP53-mutated AML/MDS without complex or monosomal karyotype can achieve durable survival benefits with allogeneic HCT

Free
Nikeshan Jeyakumar, Nancy Torres, Suneeta Godbole, Fiona Yamamoto, Bing Zhang, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Melody Smith, Wen-Kai Weng, David Miklos, Matthew Schwede, Gabriel Mannis, Tian Zhang, Lori Muffly, Vanessa Kennedy
Journal: Blood
Blood (2025) 146 (Supplement 1): 2525.
https://doi.org/10.1182/blood-2025-2525
Published: 2025
Journal Articles

Redefining post-CD19 CAR T-cell surveillance with ctdna: Real-world insights from post- axi-cel and liso-cel therapy

Free
Snegha Ananth, Jayasindhu Mallampet, Betty Chang, Neha Agarwal, Katherine Kong, Bita Sahaf, Juan Carlos Suarez Serrato, Ilan Kirsch, Allison Jacob, Heidi Simmons, Lik Wee Lee, Crystal Mackall, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 941.
https://doi.org/10.1182/blood-2025-941
Published: 2025
Journal Articles

From response to rupture: Evaluating GI perforation after CD19 CAR‑T in LBCL

Free
Arash Velayati, Masooma Rana, Alexandria Jensen, Dasom (Caroline) Lee, Nima Ghalehsari, Anmol Goyal, Theresa Latchford, William Wang, Eric Heng, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, Matthew Frank, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 2771.
https://doi.org/10.1182/blood-2025-2771
Published: 2025
Journal Articles

Double-dose axicabtagene ciloleucel (Axi-Cel-2) as second-line therapy for high-risk relapsed or refractory large B-cell lymphoma (r/rLBCL): Interim results from a Phase 1b study

Free
Dasom (Caroline) Lee, Kameron Rodrigues, Masooma Rana, Kendall Kozy, Sunny Salazar, Alexandria Jensen, Moksha Desai, Jayasindhu Mallampet, Claire Lohman, Ying-Wen Huang, Xiaoman Kang, Feng Tian, Jurik Mutter, Nick Phillips, Colleen Schweitzer, Faisal Cheema, Lekha Mikkilineni, Andrew Rezvani, Laura Johnston, Judith Shizuru, Everett Meyer, Robert Lowsky, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, Robert Negrin, Surbhi Sidana, Lori Muffly, Bita Sahaf, Yasodha Natkunam, Rhine Shen, Matthew Frank, Crystal Mackall, Zinaida Good, Ash Alizadeh, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 671.
https://doi.org/10.1182/blood-2025-671
Published: 2025
Journal Articles

Validated PET-CT metabolic tumor volume threshold identifies high-risk relapsed/refractory LBCL and predicts 12-month toxicity-free progression-free survival Post–CAR-T therapy

Free
Masooma Rana, Nima Ghalehsari, Alexandria Jensen, Dasom (Caroline) Lee, Natalie Park, Anmol Goyal, Ayesha Hashmi, William Wang, Eric Heng, Arash Velayati, Gaurav Dhapola, Ying-Wen Huang, Bita Sahaf, Wen-Kai Weng, Surbhi Sidana, Melody Smith, Sushma Bharadwaj, Matthew Frank, David Miklos, Michael Binkley, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 397.
https://doi.org/10.1182/blood-2025-397
Published: 2025
Journal Articles

Superior real-world outcomes of lisocabtagene maraleucel in chronic lymphocytic leukemia

Free
Jennifer Huang, Jenna Voutsinas, Niranjan Khaire, Vincenzo Pizzuti, Leyla Shune, Matthew Lei, Rodrigo Fonseca, Mohammad Ammad Ud Din, Alan Skarbnik, Agrima Mian, Sushma Bharadwaj, Aseel Alsouqi, Bret Wankel, Graham Wehmeyer, Joseph Lukowski, Alexey Danilov, Tanya Siddiqi, Meghan Thompson, Michael Scordo, Stephanie Franco, Deborah Stephens, Chaitra Ujjani, Ryan Lynch, Jordan Gauthier, William Wierda, Paul Barr, Adam Kittai, Jonah Shulman, Matthew Lunning, Kerry Rogers, Bita Fakhri, Brian Hill, Javier Pinilla-Ibarz, Talal Hilal, Jacob Soumerai, Manali Kamdar, Qian Wu, Nitin Jain, Mazyar Shadman
Journal: Blood
Blood (2025) 146 (Supplement 1): 798.
https://doi.org/10.1182/blood-2025-798
Published: 2025
Journal Articles

Non-response to bridging therapy prior to CAR-T is associated with increased toxicity and adverse outcomes in Relapsed/Refractory multiple myeloma (RRMM)

Free
Masooma Rana, Alexandria Jensen, Arash Velayati, Vanna Hovanky, Lori Muffly, Bita Sahaf, David Iberri, Michaela Liedtke, Sushma Bharadwaj, Vanessa Kennedy, Sally Arai, Parveen Shiraz, Wen-Kai Weng, Melody Smith, Matthew Frank, David Miklos, Saurabh Dahiya, Hitomi Hosoya, Lekha Mikkilineni, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 4586.
https://doi.org/10.1182/blood-2025-4586
Published: 2025
Journal Articles

Pre-treatment CD19 antigen density and multi-antigen profiling by calibrated quantitative flow cytometry correlates with CAR T efficacy in LBCL

Free
Jay Spiegel, Jean Oak, Masooma Rana, Alexandria Jensen, Dasom (Caroline) Lee, Sao-Mai Nguyen-Mau, Katherine Kong, Scott Bornheimer, Lekha Mikkilineni, Lori Muffly, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Matthew Frank, Rhine Shen, Crystal Mackall, Yasodha Natkunam, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 5882.
https://doi.org/10.1182/blood-2025-5882
Published: 2025
Journal Articles

CD22-directed CAR-T cells induce complete remissions in high-risk follicular and Mantle Cell Lymphoma with limited neurotoxicity

Free
Hrishikesh Srinagesh, Anne Marijn Kramer, Mark Hamilton, Yi-Jiun Su, Kendall Kozy, LaTesha Jackson, Annie Brown, Kimi DeNoble, Sharon Mavroukakis, Claire Lohman, Kristen Cunanan, Neha Agarwal, Sushma Bharadwaj, Warren Reynolds, Sally Arai, Laura Johnston, Robert Lowsky, Everett Meyer, Robert Negrin, Andrew Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa Kennedy, Melody Smith, Saurabh Dahiya, Kara Davis, Sneha Ramakrishna, Liora Schultz, Ramya Tunuguntla, Lori Muffly, Crystal Mackall, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 4159.
https://doi.org/10.1182/blood-2025-4159
Published: 2025
Journal Articles

Donor regulatory T-cell therapy to prevent graft-versus-host disease

Available to Purchase
Clinical Trials & Observations
Everett H. Meyer, Anna Pavlova, Alejandro Villar-Prados, Cameron Bader, Bryan Xie, Lori Muffly, Paige Kim, Katherine Sutherland, Sushma Bharadwaj, Saurabh Dahiya, Matthew Frank, Sally Arai, Laura Johnston, David Miklos, Andrew Rezvani, Parveen Shiraz, Surbhi Sidana, Judy Shizuru, Wen-Kai Weng, Vaibhav Agrawal, Amy Putnam, Nathaniel Fernhoff, John Tamarisis, Ying Lu, Rahul D. Pawar, J. Scott McClellan, Robert Lowsky, Robert S. Negrin
Journal: Blood
Blood (2025) 145 (18): 2012–2024.
https://doi.org/10.1182/blood.2024026446
Published: 2025
Includes: Supplemental data
Journal Articles

Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy in Octogenarian Patients (Aged ≥ 80) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Free
Dasom Lee, Sushma Bharadwaj, Masooma S Rana, Alexandria Jensen, William Wang, Nima Ghalehsari, Bita Sahaf, Jayasindhu Mallampet, Sarah Elkordy, Theresa Latchford, Sally Arai, Laura Johnston, Hitomi Hosoya, Robert Lowsky, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Everett H. Meyer, Parveen Shiraz, Lekha Mikkilineni, Wen-Kai Weng, Lauren S. Maeda, Melody Smith, Surbhi Sidana, Lori Muffly, Matthew J. Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2024) 144 (Supplement 1): 386.
https://doi.org/10.1182/blood-2024-201822
Published: 2024
Journal Articles

Anti-BCMA CAR T-Cell Expansion and Its Association with Response and Toxicity in Multiple Myeloma

Free
Hitomi Hosoya, Alexandria Jensen, Vanna Hovanky, Sylvester Homsy, Juancarlos E Cancilla, Sunita Patil, Vanessa E. Kennedy, Sushma Bharadwaj, Melody Smith, Parveen Shiraz, Matthew J. Frank, Saurabh Dahiya, Sally Arai, Wen-Kai Weng, Lori Muffly, Bita Sahaf, Crystal L. Mackall, David B. Miklos, Lekha Mikkilineni, Surbhi Sidana
Journal: Blood
Blood (2024) 144 (Supplement 1): 2006.
https://doi.org/10.1182/blood-2024-211128
Published: 2024
Journal Articles

Indolent CD8+ CAR T-Cell Lymphoma of the Gastrointestinal Tract after Ciltacabtagene Autoleucel Therapy for Relapsed/Refractory Multiple Myeloma

Free
Hitomi Hosoya, Sebastian Fernandez-Pol, John Gubatan, Zachary Ehlinger, Claire Lohman, Armando N Bastidas Torres, Safa Najidh, Alexa Kwang, George Duran, Charles Wright III, Vanessa E. Kennedy, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Matthew J. Frank, Lori Muffly, Wen-Kai Weng, Bita Sahaf, David Kurtz, Crystal L. Mackall, Michael S. Khodadoust, David B. Miklos, Surbhi Sidana, Lekha Mikkilineni
Journal: Blood
Blood (2024) 144 (Supplement 1): 4846.
https://doi.org/10.1182/blood-2024-207885
Published: 2024
Journal Articles

Investigating Treatment Kinetics and Local Response during and after Bridging Radiotherapy Prior to CAR-T Cell Therapy for Lymphomas

Free
Daniella Klebaner, Natalie Park, Mallika Marar, Matthew J. Frank, Susan Hiniker, Richard T. Hoppe, Joseph G. Schroers-Martin, Ranjana H. Advani, Ash A. Alizadeh, Sushma Bharadwaj, David B. Miklos, Saurabh Dahiya, Michael S. Binkley
Journal: Blood
Blood (2024) 144 (Supplement 1): 7130.
https://doi.org/10.1182/blood-2024-200930
Published: 2024
Journal Articles

CD22-Directed CAR T-Cell Therapy Achieves Complete Remission in CD19-Directed CAR T-Cell Refractory Follicular and Mantle Cell Lymphoma

Free
Anne Marijn Kramer, Hrishikesh Srinagesh, Yi-Jiun Su, Mark P. Hamilton, Kendall Levine, Eleonora Migliore, Kimi DeNoble, Annie K. Brown, Kristen Cunanan, Neha Agarwal, Claire Lohman, Sharon Mavroukakis, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Saurabh Dahiya, Kara L. Davis, Sneha Ramakrishna, Liora Michal Schultz, Ramya Tunuguntla, Steven A. Feldman, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2024) 144 (Supplement 1): 2064.
https://doi.org/10.1182/blood-2024-198489
Published: 2024
Journal Articles

Safe and Effective Combination of Donor-Derived, Allogeneic CD19/CD22-CAR T Cells with Myeloablative Graft-Engineered Allo-HCT for High-Risk B-ALL

Free
Lori Muffly, Snegha Ananth, Lindsay Danley, Caroline Wagner, Diana Kordek, Kimi DeNoble, Ayesha Fraser, Emily Egeler, Alfonso Molina, Zachary Ehlinger, Moksha Desai, Hossein Daghagh, Ramya Tunuguntla, Annie K. Brown, Raquel Ibañez, Anne Marijn Kramer, Zinaida Good, Sally Arai, Laura Johnston, Robert Lowsky, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Sushma Bharadwaj, Saurabh Dahiya, Matthew J. Frank, Everett H. Meyer, Robert S. Negrin, Steven A. Feldman, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Melody Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 679.
https://doi.org/10.1182/blood-2024-211959
Published: 2024
Journal Articles

CD22-Directed CAR T-Cell Therapy for Large B-Cell Lymphomas Progressing after CD19-Directed CAR T-Cell Therapy: Continued Durable Remissions at 3-Year Follow-up

Free
Anne Marijn Kramer, John H. Baird, Hrishikesh Srinagesh, Emily Egeler, Kendall Levine, Annie K. Brown, Sharon Mavroukakis, Kristen Cunanan, Yi-Jiun Su, Neha Agarwal, Mark P. Hamilton, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Saurabh Dahiya, Kara L. Davis, Sneha Ramakrishna, Liora Michal Schultz, Ramya Tunuguntla, Steven A. Feldman, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2024) 144 (Supplement 1): 69.
https://doi.org/10.1182/blood-2024-198544
Published: 2024