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Sushma Bharadwaj
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Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

CAR19 Therapy Drives Expansion of Clonal Hematopoiesis and Associated Cytopenias

Mark P. Hamilton, Brian J. Sworder, Stefan K. Alig, Zinaida Good, Jan Boegeholz, Joseph Schroers-Martin, John Tamaresis, Mohammad Shahrokh Esfahani, Ying Lu, Mari Olsen, Chih Long Liu, Zachary Ehlinger, Moksha Desai, Felicia Liu-Fei, Lori S. Muffly, Robert S. Negrin, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Andrew R. Rezvani, Judith Shizuru, Wen-Kai Weng, Parveen Shiraz, Surbhi Sidana, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Bita Sahaf, Maximilian Diehn, Matthew J. Frank, Crystal L. Mackall, David M. Kurtz, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 360.
https://doi.org/10.1182/blood-2023-182522
Published: 2023
Journal Articles

Second-Line Chimeric Antigen Receptor T Cell Therapy (CAR-T) As Standard of Care for Relapsed-Refractory Large B-Cell Lymphoma (LBCL)

Saurabh Dahiya, Jay Y. Spiegel, Dasom Lee, Turab Mohammed, Forat Lutfi, Anmol Goyal, Caroline Hana, Julio C Chavez, Filip Ionescu, Matthew J. Frank, Sushma Bharadwaj, Jose Sandoval-Sus, Amer M. Beitinjaneh, Lazaros J. Lekakis, Joseph P McGuirk, Frederick L. Locke, David B. Miklos, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 4876.
https://doi.org/10.1182/blood-2023-188918
Published: 2023
Journal Articles

Impact of Obesity on Efficacy, Safety, and Expansion Kinetics of Chimeric Antigen Receptor-T (CAR T) Therapy in Patients with Relapsed or Refractory Large B Cell Lymphoma (LBCL)

Anmol Goyal, Sushma Bharadwaj, Dasom Lee, Eric Lau, Mark P. Hamilton, Alexandria Jensen, Bita Sahaf, Shriya Syal, Sunita Patil, Juancarlos E Cancilla, Theresa Latchford, Wen-Kai Weng, Melody Smith, Matthew J. Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2023) 142 (Supplement 1): 3783.
https://doi.org/10.1182/blood-2023-186828
Published: 2023
Journal Articles

Post-CAR-T Minimal Residual Disease (MRD) Monitoring in Mantle Cell Lymphoma Enables Early Relapse Detection

Snegha Ananth, Yi-Jiun Su, Mark P. Hamilton, Neha Agarwal, Wen-Kai Weng, Saurabh Dahiya, Sushma Bharadwaj, Jayasindhu Mallampet, Melody Smith, Katherine Ann Kong, Abigail Twoy, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 1673.
https://doi.org/10.1182/blood-2023-188338
Published: 2023
Journal Articles

Analysis of PET-CT Derived Radiomic Biomarkers with Efficacy, Safety, and Expansion of Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed or Refractory Large B-Cell Lymphoma (LBCL)

Sushma Bharadwaj, Eric Lau, Ayesha Hashmi, Mark P. Hamilton, Alexandria Jensen, Anmol Goyal, Mallika Marar, Caroline Lee, Snegha Ananth, Bita Sahaf, Jayasindhu Mallampet, Zachary Ehlinger, Shriya Syal, Sunita Patil, Henry Guo, Melody Smith, Wen-Kai Weng, Matthew J. Frank, Michael S. Binkley, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2023) 142 (Supplement 1): 2125.
https://doi.org/10.1182/blood-2023-187617
Published: 2023
Journal Articles

CD22 CAR T Cell-Related IEC-HS Is Associated with an IFN-γ Cytokine Signature

Hrishikesh Srinagesh, John H. Baird, Neha Agarwal, Yi-Jiun Su, Anne Marijn Kramer, Agnes Reschke, Nikeshan Jeyakumar, Sushma Bharadwaj, Liora Michal Schultz, Sneha Ramakrishna, Kara L. Davis, Bita Sahaf, Steven Feldman, Crystal L. Mackall, David B. Miklos, Lori S. Muffly, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 4839.
https://doi.org/10.1182/blood-2023-178283
Published: 2023
Journal Articles

Phase 1 Trial Results for Patients with Advanced Hematologic Malignancies Undergoing Reduced Intensity Allogeneic HCT with Orca-T Donor Cell Therapy Product and Single Agent Tacrolimus

Alejandro Villar-Prados, Everett H. Meyer, Katherine Sutherland, Robert S. Negrin, Sally Arai, Matthew J. Frank, Laura Johnston, Robert Lowsky, David B. Miklos, Lori S. Muffly, Saurabh Dahiya, Andrew R. Rezvani, Surbhi Sidana, Parveen Shiraz, Judith Shizuru, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, John Tamaresis, Anna Pavlova, Scott McClellan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3560.
https://doi.org/10.1182/blood-2023-188162
Published: 2023
Journal Articles

Long-Term Efficacy and Immune Reconstitution with Bendamustine As a Lymphodepleting Agent for Axicabtagene Ciloleucel (Axi-Cel) in Patients with Refractory or Relapsed Large B-Cell Lymphoma (LBCL)

Sushma Bharadwaj, Eric Lau, Anmol Goyal, Mark P. Hamilton, Hrishikesh Srinagesh, Alexandria Jensen, Shriya Syal, Jayasindhu Mallampet, Theresa Latchford, Bita Sahaf, Wen-Kai Weng, Melody Smith, Holden T Maecker, Matthew J. Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2023) 142 (Supplement 1): 4878.
https://doi.org/10.1182/blood-2023-188166
Published: 2023
Journal Articles

Higher Rates of Severe Infection and Persistent Cytopenias in Long-Term CAR19 Responders Than after Autologous HCT: A Single Institution Study of 139 Subjects

Mark P Hamilton, Felicia C Liu-Fei, Stefan K. Alig, John Tamaresis, Mohammad Shahrokh Esfahani, Zinaida Good, Brian Sworder, Joseph Schroers-Martin, Chih Long Liu, Freja Tang Severinsen, Paul J Hanson, Ying Lu, Robert Lowsky, Robert S. Negrin, Everett H Meyer, Melody Smith, Sushma Bharadwaj, Judith A Shizuru, Surbhi Sidana, Parveen Shiraz, Andrew R. Rezvani, Laura J. Johnston, Wen-Kai Weng, Sally Arai, Lori Muffly, Saurabh Dahiya, Maximilian Diehn, David M. Kurtz, Bita Sahaf, Crystal L. Mackall, Matthew J Frank, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 7545–7547.
https://doi.org/10.1182/blood-2022-165600
Published: 2022
Journal Articles

Outcomes for Acute Myeloid Leukemia Relapse after Allogeneic Hematopoietic Cell Transplantation Remain Poor in the Modern Era

Shona Philip, Robert Lowsky, Laura J. Johnston, Sally Arai, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Judith A. Shizuru, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Matthew J. Frank, David B. Miklos, Melody Smith, Lori Muffly, Vaibhav Agrawal
Journal: Blood
Blood (2022) 140 (Supplement 1): 4825–4827.
https://doi.org/10.1182/blood-2022-168546
Published: 2022
Journal Articles

The Development of Carhlh after Axicabtagene Ciloleucel Is Associated with Poor Outcomes

Shona Philip, Hrishikesh K. Srinagesh, Mark P Hamilton, Cesar Gentille, Alain Mina, Sally Arai, Laura J. Johnston, Robert Lowsky, Everett H Meyer, Robert S. Negrin, Andrew R. Rezvani, Parveen Shiraz, Judith A Shizuru, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Saurabh Dahiya, Lori Muffly, Melody Smith, David B. Miklos, Matthew J Frank
Journal: Blood
Blood (2022) 140 (Supplement 1): 12775–12777.
https://doi.org/10.1182/blood-2022-170877
Published: 2022
Journal Articles

Idecabtagene Vicleucel Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Multiple Myeloma with Renal Insufficiency: Real World Experience

Surbhi Sidana, Lauren C. Peres, Hamza Hashmi, Hitomi Hosoya, Christopher J. Ferreri, Shebli Atrash, Jack Khouri, Peter M. Voorhees, Danai Dima, Gary Simmons, Nilesh Kalariya, Vanna Hovanky, Sushma Bharadwaj, Sally Arai, David B. Miklos, Charlotte B Wagner, James Davis, Douglas W. Sborov, Taiga Nishihori, Melissa Alsina, Frederick L. Locke, Rebecca Gonzalez, M. Hakan Kocoglu, Aishwarya Sannareddy, Aimaz Afrough, Joseph P. McGuirk, Leyla O. Shune, Krina Patel, Doris K. Hansen
Journal: Blood
Blood (2022) 140 (Supplement 1): 10377–10379.
https://doi.org/10.1182/blood-2022-166058
Published: 2022
Journal Articles

Analysis of Bendamustine Lymphodepletion, CD19 CART Expansion, Safety and Efficacy in Patients with Rel/Ref Non-Hodgkin Lymphoma

Sushma Bharadwaj, Mark P Hamilton, Bita Sahaf, John Tamaresis, Sunita Patil, Paul J Hanson, Theresa Latchford, Sally Arai, Laura J. Johnston, Robert Lowsky, Robert S. Negrin, Andrew R. Rezvani, Judith A Shizuru, Everett H Meyer, Parveen Shiraz, Surbhi Sidana, Melody Smith, Wen-Kai Weng, Lori Muffly, Crystal L. Mackall, Matthew J Frank, David B. Miklos, Saurabh Dahiya
Journal: Blood
Blood (2022) 140 (Supplement 1): 10371–10373.
https://doi.org/10.1182/blood-2022-170759
Published: 2022
Journal Articles

Belumosudil Combination Therapy in Refractory Chronic Graft-Versus-Host Disease

Michelle Chin, Judith A. Shizuru, Lori Muffly, Parveen Shiraz, Laura J. Johnston, Robert Lowsky, Andrew R. Rezvani, Matthew J. Frank, Sushma Bharadwaj, Wen-Kai Weng, Robert S. Negrin, David B. Miklos, Sally Arai
Journal: Blood
Blood (2022) 140 (Supplement 1): 4788–4789.
https://doi.org/10.1182/blood-2022-165547
Published: 2022
Journal Articles

Structural racism is a mediator of disparities in acute myeloid leukemia outcomes

Clinical Trials & Observations
Ivy Elizabeth Abraham, Garth H. Rauscher, Anand Ashwin Patel, William B. Pearse, Priya Rajakumar, Madelyn Burkart, Ahmed Aleem, Ami Dave, Sushma Bharadwaj, Koosha Paydary, Maria Acevedo-Mendez, Krishna Goparaju, Richard Gomez, Kylie Carlson, Stephanie B. Tsai, John G. Quigley, John P. Galvin, Maryam Zia, Melissa L. Larson, Stephanie Berg, Wendy Stock, Jessica K. Altman, Irum Khan
Journal: Blood
Blood (2022) 139 (14): 2212–2226.
https://doi.org/10.1182/blood.2021012830
Published: 2022
Includes: Supplemental data
Journal Articles

The Role of Structural Violence in Acute Myeloid Leukemia Outcomes

Ivy Abraham, MD, Garth Rauscher, PhD MPH, Anand Ashwin Patel, MD, William B Pearse, MD, Priya Rajakumar, MD, Stephanie Berg, DO, Ahmed Aleem, MD, Ami Dave, MD, Sushma Bharadwaj, MD, Koosha Paydary, MD, Maria Acevedo-Mendez, Richard Gomez, Kylie Carlson, Stephanie B. Tsai, MD MS, Jessica K. Altman, MD, Wendy Stock, MD, John G. Quigley, Maryam Zia, MD, Melissa C. Larson, MD, Irum Khan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-136379
Published: 2020
Journal Articles

Role of Racial, Demographic and Socioeconomic Disparities in Treatment Patterns and Outcomes in AML

Ivy Abraham, MD, Garth Rauscher, PhD MPH, Anand Ashwin Patel, MD, Wendy Stock, MD, Maryam Zia, MD, Sushma Bharadwaj, MD, Koosha Paydary, MD, Maria Acevedo-Mendez, John P Galvin, MDMS,MPH, William Pearse, MD, Jessica K. Altman, John G. Quigley, Priya Rajakumar, MD, Melissa L. Larson, MD, Irum Khan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3413.
https://doi.org/10.1182/blood-2019-124974
Published: 2019