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Journal Articles

From response to rupture: Evaluating GI perforation after CD19 CAR‑T in LBCL

Free
Arash Velayati, Masooma Rana, Alexandria Jensen, Dasom (Caroline) Lee, Nima Ghalehsari, Anmol Goyal, Theresa Latchford, William Wang, Eric Heng, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, Matthew Frank, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 2771.
https://doi.org/10.1182/blood-2025-2771
Published: 2025
Journal Articles

Redefining post-CD19 CAR T-cell surveillance with ctdna: Real-world insights from post- axi-cel and liso-cel therapy

Free
Snegha Ananth, Jayasindhu Mallampet, Betty Chang, Neha Agarwal, Katherine Kong, Bita Sahaf, Juan Carlos Suarez Serrato, Ilan Kirsch, Allison Jacob, Heidi Simmons, Lik Wee Lee, Crystal Mackall, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 941.
https://doi.org/10.1182/blood-2025-941
Published: 2025
Journal Articles

CD22-CAR T cell multiomic features linked to patient outcomes in CD19-CAR resistant large B cell lymphoma

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Kameron Rodrigues, Mark Hamilton, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren Reynolds, Hrishikesh Srinagesh, Kristin Tsui, Skyler Rietberg, Kelvin Mo, John Baird, Yi-Jiun Su, Neha Agarwal, Elena Sotillo, Snehit Prabhu, Bita Sahaf, Saurabh Dahiya, Sneha Ramakrishna, Lori Muffly, Crystal Mackall, David Miklos, Zinaida Good, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 566.
https://doi.org/10.1182/blood-2025-566
Published: 2025
Journal Articles

Real-world effectiveness and safety outcomes by age, comorbidity, frailty, and treatments prior to infusion in relapsed or refractory (R/R) follicular lymphoma patients treated with axicabtagene ciloleucel

Free
Aung Tun, Matthew Frank, Madiha Iqbal, Alex Herrera, Mehdi Hamadani, Waleska Pérez, Soyoung Kim, Babatunde Adedokun, Constance Lau, Kenny Hu, Timothy Best, Olga Nikolajeva, Grace Lee, Marcelo Pasquini, Caron Jacobson
Journal: Blood
Blood (2025) 146 (Supplement 1): 5356.
https://doi.org/10.1182/blood-2025-5356
Published: 2025
Journal Articles

Double-dose axicabtagene ciloleucel (Axi-Cel-2) as second-line therapy for high-risk relapsed or refractory large B-cell lymphoma (r/rLBCL): Interim results from a Phase 1b study

Free
Dasom (Caroline) Lee, Kameron Rodrigues, Masooma Rana, Kendall Kozy, Sunny Salazar, Alexandria Jensen, Moksha Desai, Jayasindhu Mallampet, Claire Lohman, Ying-Wen Huang, Xiaoman Kang, Feng Tian, Jurik Mutter, Nick Phillips, Colleen Schweitzer, Faisal Cheema, Lekha Mikkilineni, Andrew Rezvani, Laura Johnston, Judith Shizuru, Everett Meyer, Robert Lowsky, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, Robert Negrin, Surbhi Sidana, Lori Muffly, Bita Sahaf, Yasodha Natkunam, Rhine Shen, Matthew Frank, Crystal Mackall, Zinaida Good, Ash Alizadeh, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 671.
https://doi.org/10.1182/blood-2025-671
Published: 2025
Journal Articles

Firicabtagene autoleucel (firi-cel), a CD22-directed CAR T-cell therapy, for patients with relapsed/refractory large B-cell lymphoma: Results from the phase 2 study (FIRCE-1 Trial)

Free
Matthew Frank, David Qualls, Armin Ghobadi, Jordan Gauthier, Michael Tees, Luke Mountjoy, Joseph McGuirk, Sattva Neelapu, Reem Karmali, Iris Isufi, Brian Hill, Craig Sauter, Catherine Diefenbach, Jay Spiegel, Lizamarie Bachier-Rodriguez, Monalisa Ghosh, Nirav Shah, Rahul Lakhotia, Francisco Hernandez-Ilizaliturri, Anuja Abhyankar, Elise Chong, Matthew Schwede, Krish Patel, Olalekan Oluwole, John Baird, Nathan Denlinger, Farrukh Awan, Michael Jain, John Timmerman, Cesar Sanchez, Muthu Kumaran, Jean Yared, Jon Arnason, Ishan Tatake, Usama Gergis, Peter Riedell, Keith Pratz, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 667.
https://doi.org/10.1182/blood-2025-667
Published: 2025
Journal Articles

Validated PET-CT metabolic tumor volume threshold identifies high-risk relapsed/refractory LBCL and predicts 12-month toxicity-free progression-free survival Post–CAR-T therapy

Free
Masooma Rana, Nima Ghalehsari, Alexandria Jensen, Dasom (Caroline) Lee, Natalie Park, Anmol Goyal, Ayesha Hashmi, William Wang, Eric Heng, Arash Velayati, Gaurav Dhapola, Ying-Wen Huang, Bita Sahaf, Wen-Kai Weng, Surbhi Sidana, Melody Smith, Sushma Bharadwaj, Matthew Frank, David Miklos, Michael Binkley, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 397.
https://doi.org/10.1182/blood-2025-397
Published: 2025
Journal Articles

Allogeneic HSC and regulatory T cell  (Orca-T) engineered cell therapy following reduced intensity conditioning: Results of a single center Phase 1 study

Free
Alejandro Villar-Prados, Paige Kim, Katherine Sutherland, Robert Negrin, Sally Arai, Matthew Frank, Laura Johnston, Robert Lowsky, David Miklos, Lori Muffly, Saurabh Dahiya, Andrew Rezvani, Surbhi Sidana, Parveen Shiraz, Judith Shizuru, Wen-Kai Weng, Melody Smith, Sushma Bharadwaj, John Tamaresis, Anna Pavlova, J. Scott McClellan, Everett Meyer
Journal: Blood
Blood (2025) 146 (Supplement 1): 111.
https://doi.org/10.1182/blood-2025-111
Published: 2025
Journal Articles

Patients with TP53-mutated AML/MDS without complex or monosomal karyotype can achieve durable survival benefits with allogeneic HCT

Free
Nikeshan Jeyakumar, Nancy Torres, Suneeta Godbole, Fiona Yamamoto, Bing Zhang, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Melody Smith, Wen-Kai Weng, David Miklos, Matthew Schwede, Gabriel Mannis, Tian Zhang, Lori Muffly, Vanessa Kennedy
Journal: Blood
Blood (2025) 146 (Supplement 1): 2525.
https://doi.org/10.1182/blood-2025-2525
Published: 2025
Journal Articles

CD22-directed CAR-T cells induce complete remissions in high-risk follicular and Mantle Cell Lymphoma with limited neurotoxicity

Free
Hrishikesh Srinagesh, Anne Marijn Kramer, Mark Hamilton, Yi-Jiun Su, Kendall Kozy, LaTesha Jackson, Annie Brown, Kimi DeNoble, Sharon Mavroukakis, Claire Lohman, Kristen Cunanan, Neha Agarwal, Sushma Bharadwaj, Warren Reynolds, Sally Arai, Laura Johnston, Robert Lowsky, Everett Meyer, Robert Negrin, Andrew Rezvani, Judith Shizuru, Lekha Mikkilineni, Hitomi Hosoya, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa Kennedy, Melody Smith, Saurabh Dahiya, Kara Davis, Sneha Ramakrishna, Liora Schultz, Ramya Tunuguntla, Lori Muffly, Crystal Mackall, David Miklos, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 4159.
https://doi.org/10.1182/blood-2025-4159
Published: 2025
Journal Articles

Sequential CD19 and CD22 CART for relapsed and refractory B cell ALL: Phase I results

Free
Liora Schultz, Catherine Aftandilian, Christina Baggott, Nicole Corwin, Michelle Fujimoto, Amy Li, Sharon Mavroukakis, Jennifer Moon, Bita Sahaf, Ashley Jacobs, Emily DeYager, Cristina Mendoza, Andrea Levenson, Matthew Frank, David Miklos, Lori Muffly, Steven Feldman, Janette Alcazar, Ramya Tunuguntla, Annie Brown, Raya Saab, Jay Balagtas, Tanja Gruber, Pablo Domizi, Sneha Ramakrishna, Crystal Mackall, Kara Davis
Journal: Blood
Blood (2025) 146 (Supplement 1): 2374.
https://doi.org/10.1182/blood-2025-2374
Published: 2025
Journal Articles

Superior efficacy and persistence of Orca-T-allogeneic CAR19/22 versus autologous CAR19/22 in high-risk adult B-ALL

Free
Alfonso Molina, Parveen Shiraz, Alyssa Kanegai, Ayesha Fraser, Diana Kordek, Caroline Wagner, Hrishikesh Srinagesh, Lindsay Danley, Arvind Ramakrishnan, Hossein Daghagh, Ying-Wen Huang, Gaurav Dhapola, Aman Siddiqui, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Vanessa Kennedy, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Wen-Kai Weng, Catherine McIntyre, Steven Feldman, Bita Sahaf, Crystal Mackall, David Miklos, Lori Muffly, Melody Smith
Journal: Blood
Blood (2025) 146 (Supplement 1): 514.
https://doi.org/10.1182/blood-2025-514
Published: 2025
Journal Articles

Non-response to bridging therapy prior to CAR-T is associated with increased toxicity and adverse outcomes in Relapsed/Refractory multiple myeloma (RRMM)

Free
Masooma Rana, Alexandria Jensen, Arash Velayati, Vanna Hovanky, Lori Muffly, Bita Sahaf, David Iberri, Michaela Liedtke, Sushma Bharadwaj, Vanessa Kennedy, Sally Arai, Parveen Shiraz, Wen-Kai Weng, Melody Smith, Matthew Frank, David Miklos, Saurabh Dahiya, Hitomi Hosoya, Lekha Mikkilineni, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 4586.
https://doi.org/10.1182/blood-2025-4586
Published: 2025
Journal Articles

Pre-treatment CD19 antigen density and multi-antigen profiling by calibrated quantitative flow cytometry correlates with CAR T efficacy in LBCL

Free
Jay Spiegel, Jean Oak, Masooma Rana, Alexandria Jensen, Dasom (Caroline) Lee, Sao-Mai Nguyen-Mau, Katherine Kong, Scott Bornheimer, Lekha Mikkilineni, Lori Muffly, Surbhi Sidana, Wen-Kai Weng, Sushma Bharadwaj, Melody Smith, Matthew Frank, Rhine Shen, Crystal Mackall, Yasodha Natkunam, David Miklos, Saurabh Dahiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 5882.
https://doi.org/10.1182/blood-2025-5882
Published: 2025
Journal Articles

Post-transplant cyclophosphamide vs tacrolimus/methotrexate: Improved GRFS, reduced NRM, and less severe GVHD in myeloablative HLA-matched allogeneic transplantation

Free
Alfonso Molina, Quenton Bubb, Ryan Yee, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Melody Smith, Wen-Kai Weng, David Miklos, Lori Muffly, Vanessa Kennedy
Journal: Blood
Blood (2025) 146 (Supplement 1): 2494.
https://doi.org/10.1182/blood-2025-2494
Published: 2025
Journal Articles

Real-world outcomes of immune effector cell-associated hemophagocytic syndrome (IEC-HS) following ide-cel and cilta-cel therapy in relapsed/refractory multiple myeloma

Free
Jerry Lee, Alexandria Jensen, Hitomi Hosoya, Aimaz Afrough, Saurabh Zanwar, Oren Pasvolsky, Mahmoud Gaballa, Christen Dillard, Jack Khouri, Shahzad Raza, Utkarsh Goel, Faiz Anwer, Vanna Hovanky, Masooma Rana, James Davis, Kimberly Green, Larry Anderson, Noa Biran, Eli Zolotov, Megan Herr, Hamza Hassan, Leyla Shune, Jeries Kort, Christopher Ferreri, Shebli Atrash, Cindy Varga, Peter Voorhees, Douglas Sborov, Gliceida Fortuna, Kelley Julian, Danai Dima, Andrew Portuguese, Rahul Banerjee, Ciara Louise Freeman, Karla Feliciano Salva, Raffaella Cassano Cassano, Lauren Peres, Brett Reid, Omar Alexis Castaneda Puglianini, Ariel Grajales-Cruz, Michael Jain, Krina Patel, Frederick Locke, Matthew Frank, Yi Lin, Doris Hansen, Surbhi Sidana, Nirali Shah, Lekha Mikkilineni
Journal: Blood
Blood (2025) 146 (Supplement 1): 719.
https://doi.org/10.1182/blood-2025-719
Published: 2025
Journal Articles

Optimal ferritin threshold to diagnose immune effector cell-associated hemophagocytic syndrome (IEC-HS) following CAR-T therapy in relapsed/refractory multiple myeloma (RRMM)

Free
Jerry Lee, Alexandria Jensen, Hitomi Hosoya, Saurabh Zanwar, Oren Pasvolsky, Mahmoud Gaballa, Christen Dillard, Jack Khouri, Shahzad Raza, Utkarsh Goel, Faiz Anwer, Vanna Hovanky, Masooma Rana, James Davis, Kimberly Green, Aimaz Afrough, Larry Anderson, Noa Biran, Eli Zolotov, Megan Herr, Hamza Hassan, Leyla Shune, Jeries Kort, Christopher Ferreri, Shebli Atrash, Cindy Varga, Peter Voorhees, Douglas Sborov, Gliceida Fortuna, Kelley Julian, Danai Dima, Rahul Banerjee, Ciara Louise Freeman, Andrew Portuguese, Raffaella Cassano Cassano, Frederick Locke, Karla J Salva, Lauren Peres, Brett Reid, Omar Alexis Castaneda Puglianini, Ariel Grajales-Cruz, Michael Jain, Krina Patel, Matthew Frank, Yi Lin, Doris Hansen, Surbhi Sidana, Nirali Shah, Lekha Mikkilineni
Journal: Blood
Blood (2025) 146 (Supplement 1): 717.
https://doi.org/10.1182/blood-2025-717
Published: 2025
Journal Articles

Donor regulatory T-cell therapy to prevent graft-versus-host disease

Available to Purchase
Clinical Trials & Observations
Everett H. Meyer, Anna Pavlova, Alejandro Villar-Prados, Cameron Bader, Bryan Xie, Lori Muffly, Paige Kim, Katherine Sutherland, Sushma Bharadwaj, Saurabh Dahiya, Matthew Frank, Sally Arai, Laura Johnston, David Miklos, Andrew Rezvani, Parveen Shiraz, Surbhi Sidana, Judy Shizuru, Wen-Kai Weng, Vaibhav Agrawal, Amy Putnam, Nathaniel Fernhoff, John Tamarisis, Ying Lu, Rahul D. Pawar, J. Scott McClellan, Robert Lowsky, Robert S. Negrin
Journal: Blood
Blood (2025) 145 (18): 2012–2024.
https://doi.org/10.1182/blood.2024026446
Published: 2025
Includes: Supplemental data