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Steven Feldman
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Journal Articles

Superior efficacy and persistence of Orca-T-allogeneic CAR19/22 versus autologous CAR19/22 in high-risk adult B-ALL

Free
Alfonso Molina, Parveen Shiraz, Alyssa Kanegai, Ayesha Fraser, Diana Kordek, Caroline Wagner, Hrishikesh Srinagesh, Lindsay Danley, Arvind Ramakrishnan, Hossein Daghagh, Ying-Wen Huang, Gaurav Dhapola, Aman Siddiqui, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hany Elmariah, Matthew Frank, Hitomi Hosoya, Vanessa Kennedy, Laura Johnston, Everett Meyer, Lekha Mikkilineni, Robert Lowsky, Robert Negrin, Andrew Rezvani, Judith Shizuru, Surbhi Sidana, Wen-Kai Weng, Catherine McIntyre, Steven Feldman, Bita Sahaf, Crystal Mackall, David Miklos, Lori Muffly, Melody Smith
Journal: Blood
Blood (2025) 146 (Supplement 1): 514.
https://doi.org/10.1182/blood-2025-514
Published: 2025
Journal Articles

Sequential CD19 and CD22 CART for relapsed and refractory B cell ALL: Phase I results

Free
Liora Schultz, Catherine Aftandilian, Christina Baggott, Nicole Corwin, Michelle Fujimoto, Amy Li, Sharon Mavroukakis, Jennifer Moon, Bita Sahaf, Ashley Jacobs, Emily DeYager, Cristina Mendoza, Andrea Levenson, Matthew Frank, David Miklos, Lori Muffly, Steven Feldman, Janette Alcazar, Ramya Tunuguntla, Annie Brown, Raya Saab, Jay Balagtas, Tanja Gruber, Pablo Domizi, Sneha Ramakrishna, Crystal Mackall, Kara Davis
Journal: Blood
Blood (2025) 146 (Supplement 1): 2374.
https://doi.org/10.1182/blood-2025-2374
Published: 2025
Journal Articles

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

Free
Clinical Trials & Observations
Hrishikesh Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura Johnston, Vanessa Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert Negrin, Andrew Rezvani, Surbhi Sidana, Judith Shizuru, Melody Smith, Wen-Kai Weng, Steven Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A. Mario Marcondes, David Miklos, Crystal Mackall, Lori Muffly
Journal: Blood
Blood (2024) 144 (16): 1689–1698.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

One Year Follow-up on the First Patient Treated with Nula-Cel: An Autologous CRISPR/Cas9 Gene Corrected CD34+ Cell Product to Treat Sickle Cell Disease

Free
David C Shyr, Robert Lowsky, Weston Miller, Mark A. Schroeder, Tonia Buchholz, Kirstin Dougall, Allison Intondi, Alexandra Charles, Josh Lehrer, Ali Bouge, Stacey Wolf, Blair MacDonald, Hena Din, Alana Lerner, Manal Amoury, Sebastien Treusch, Glen Chew, Brian Silva, Haider Mashhedi, Vincent Siu, Ian Perrone, Twaritha Vijay, Aayami Jain, Kristina Krassovsky, William Matern, Premanjali Lahiri, Ryan Rodriguez, Jason Skowronski, Arpit Batish, Dana Margittai, Prachi Wani, Timothy Van Horn, Claudia Flautero, Rosalva Flores, Jade Lee, Keri Tate, Maria-Grazia Roncarolo, Steven Feldman, John DiPersio, Matthew Porteus
Journal: Blood
Blood (2023) 142 (Supplement 1): 5000.
https://doi.org/10.1182/blood-2023-188963
Published: 2023
Journal Articles

Manufacturing of a Subsequent Autologous CAR-T Product after Prior CAR-T Is Safe and Feasible

Free
Yi-Jiun Su, Anne Marijn Kramer, Mark P. Hamilton, Neha Agarwal, Steven Feldman, Bita Sahaf, Adam Kuo, Crystal L. Mackall, Lori S. Muffly, David B. Miklos, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 1037.
https://doi.org/10.1182/blood-2023-185413
Published: 2023
Journal Articles

CD22 CAR T Cell-Related IEC-HS Is Associated with an IFN-γ Cytokine Signature

Free
Hrishikesh Srinagesh, John H. Baird, Neha Agarwal, Yi-Jiun Su, Anne Marijn Kramer, Agnes Reschke, Nikeshan Jeyakumar, Sushma Bharadwaj, Liora Michal Schultz, Sneha Ramakrishna, Kara L. Davis, Bita Sahaf, Steven Feldman, Crystal L. Mackall, David B. Miklos, Lori S. Muffly, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 4839.
https://doi.org/10.1182/blood-2023-178283
Published: 2023
Journal Articles

Transcriptional Profiling Associated with CD22 CAR T Cell Clinical Response in LBCL

Free
Anne Marijn Kramer, Mark P. Hamilton, Snehit Prabhu, Moksha Desai, Adam Kuo, Zachary Ehlinger, Neha Agarwal, Yi-Jiun Su, Nikolaos Gkitsas, Carley Fowler, Vimal Keerthi, Aidan Retherford, Dorota Klysz, Ramya Tunuguntla, Steven Feldman, Bita Sahaf, John H. Baird, Lori S. Muffly, Crystal L. Mackall, David B. Miklos, Zinaida Good, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 2091.
https://doi.org/10.1182/blood-2023-187615
Published: 2023
Journal Articles

Allogeneic T-Cells Expressing an Anti-CD19 Chimeric Antigen Receptor Cause Remissions of B-Cell Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation without Causing Graft-Versus-Host Disease

Free
Jennifer N Brudno, MD, Robert Somerville, Victoria Shi, Jeremy J. Rose, BA, David C. Halverson, MD, Daniel H. Fowler, MD, Dennis D. Hickstein, MD, Juan C. Gea-Banacloche, MD, Steven Z. Pavletic, Andre Goy, MD, Tangying L Lu, Steven Feldman, Alex Iwamoto, Roger Kurlander, Irina Maric, Brenna Hansen, Jennifer S. Wilder, RN, Bazetta Blacklock-Shuver, Frances T. Hakim, Steven A. Rosenberg, MD PhD, Ronald E. Gress, MD, James N. Kochenderfer, MD
Journal: Blood
Blood (2015) 126 (23): 99.
https://doi.org/10.1182/blood.V126.23.99.99
Published: 2015
Journal Articles

Remissions of Multiple Myeloma during a First-in-Humans Clinical Trial of T Cells Expressing an Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor

Free
Syed Abbas Ali, MD, Victoria Shi, Michael Wang, MD, David Stroncek, MD, Irina Maric, Jennifer N Brudno, MD, Maryalice Stetler-Stevenson, Jeremy J. Rose, BA, Steven Feldman, Brenna Hansen, Frances T. Hakim, PhD, Ronald E. Gress, MD, James N. Kochenderfer, MD
Journal: Blood
Blood (2015) 126 (23): LBA-1.
https://doi.org/10.1182/blood.V126.23.LBA-1.LBA-1
Published: 2015
Journal Articles

Anti-CD19 CAR T Cells Administered after Low-Dose Chemotherapy Can Induce Remissions of Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma

Free
James N Kochenderfer, MD, Robert Somerville, PhD, Lily Lu, PhD, Alex Iwamoto, B.S., James C Yang, MD, Christopher Klebanoff, MD, Udai Kammula, MD, Richard M Sherry, MD, Shi Victoria, M.S., Constance Yuan, MD PhD, Steven Feldman, PhD, Tatyana Feldman, MD, Andre Goy, MD MS, Kathleen E Morton, RN, Mary Ann Toomey, RN, Steven A. Rosenberg, MD PhD
Journal: Blood
Blood (2014) 124 (21): 550.
https://doi.org/10.1182/blood.V124.21.550.550
Published: 2014
Journal Articles

Intent-to-Treat Results of a Phase I Trial of CD19 Chimeric Antigen Receptor Engineered T Cells Using a Consistent Treatment Regimen Reveals a 67% Complete Response Rate in Relapsed, Refractory Acute Lymphoblastic Leukemia

Free
Daniel W. Lee, MD, Maryalice Stetler-Stevenson, MD PhD, Marianna Sabatino, MD, Constance Yuan, MD PhD, Terry J Fry, MD, Nirali N Shah, MD, Cindy Delbrook, RN, Bonnie Yates, RN, Hua Zhang, PhD, Ling Zhang, Nick Tschernia, BS, Yongzhi Cui, MD PhD, Steven Feldman, PhD, James N Kochenderfer, MD, Steven A. Rosenberg, MD, PhD, David F. Stroncek, MD, Alan S. Wayne, MD, Crystal L Mackall, MD
Journal: Blood
Blood (2014) 124 (21): 381.
https://doi.org/10.1182/blood.V124.21.381.381
Published: 2014
Journal Articles

Effective Treatment Of Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma With Autologous T Cells Genetically-Engineered To Express An Anti-CD19 Chimeric Antigen Receptor

Free
James N. Kochenderfer, M.D., Mark E. Dudley, Ph.D., Sadik H. Kassim, Ph.D., Robert O. Carpenter, James C. Yang, MD, Giao Q. Phan, MD, Marybeth S. Hughes, MD, Richard M. Sherry, MD, Steven Feldman, Ph.D., David Spaner, MD, PhD, Debbie-Ann N. Nathan, RN, Kathleen E. Morton, RN, Mary Ann Toomey, RN, Steven A. Rosenberg, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 168.
https://doi.org/10.1182/blood.V122.21.168.168
Published: 2013
Journal Articles

Donor-Derived Anti-CD19 Chimeric-Antigen-Receptor-Expressing T Cells Cause Regression Of Malignancy Persisting After Allogeneic Hematopoietic Stem Cell Transplantation

Free
James N Kochenderfer, M.D., Mark E. Dudley, Ph.D., Robert O. Carpenter, Sadik H Kassim, Ph.D., Jeremy J. Rose, William Telford, Ph.D., Frances T Hakim, PhD, David Halverson, MD, Daniel H. Fowler, MD, Nancy M. Hardy, MD, Anthony Mato, Dennis D. Hickstein, M.D., Juan Gea-Banacloche, MD, Steven Z. Pavletic, MD, Claude Sportes, MD, Irina Maric, MD, Steven Feldman, Ph.D., Brenna G Hansen, RN, Jennifer Wilder, RN, Bazetta Blacklock-Schuver, RN, Bipulendu Jena, PhD, Michael Bishop, MD, Steven A. Rosenberg, M.D., Ph.D., Ronald E. Gress, MD
Journal: Blood
Blood (2013) 122 (21): 151.
https://doi.org/10.1182/blood.V122.21.151.151
Published: 2013
Journal Articles

B-Cell Depletion, Remissions of Malignancy, and Cytokine-Associated Toxicity in a Clinical Trial of T Cells Genetically-Engineered to Express An Anti-CD19 Chimeric Antigen Receptor

Free
James N Kochenderfer, Mark E. Dudley, Steven Feldman, Wyndham H. Wilson, MD, PhD, David Spaner, Laura Devillier, Robert Carpenter, Debbie-Ann N. Nathan, Irina Maric, Richard A. Morgan, Steven A. Rosenberg
Journal: Blood
Blood (2011) 118 (21): 167.
https://doi.org/10.1182/blood.V118.21.167.167
Published: 2011
Journal Articles

Construction and Pre-Clinical Evaluation of An Anti-CD19 Chimeric Antigen Receptor

Free
James Kochenderfer, M.D., Steven Feldman, PhD, Yangbing Zhao, PhD, Hui Xu, Mary Black, Richard Morgan, PhD, Mark Dudley, PhD, Wyndham Wilson, MD, PhD, Steven Rosenberg, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 4623.
https://doi.org/10.1182/blood.V112.11.4623.4623
Published: 2008