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Journal Articles

JAK2/mTOR Inhibition Fails to Prevent Acute GVHD Despite Reduced Th1/Th17 cells: Final Phase II Trial Results

Clinical Trials & Observations
Joseph A Pidala, Shernan G Holtan, Kelly Walton, Jongphil Kim, Biwei Cao, Hany Elmariah, Asmita Mishra, Nelli Bejanyan, Taiga Nishihori, Farhad Khimani, Lia E Perez, Rawan G Faramand, Marco L. Davila, Shannon McSain, Jordan Pleskow, Jeffrey Baron, Claudio Anasetti, Carlos M Moran Segura, Daniel J Weisdorf, Bruce R Blazar, Jeffrey S. Miller, Veronika Bachanova, Najla El Jurdi, Brian C Betts
Journal: Blood
Blood blood.2024024789.
https://doi.org/10.1182/blood.2024024789
Published: 2024
Includes: Supplemental data
Journal Articles

Clinical Outcomes of Adults Undergoing Allogeneic Stem Cell Transplant for Secondary Acute Lymphoblastic Leukemia

Vivian Irizarry Gatell, Denise Kalos, Joseph A. Pidala, Hany Elmariah, Farhad Khimani, Asmita Mishra, Taiga Nishihori, Michael D. Jain, Michael Neider, Lia Perez, Sayeef Mirza, Bijal D. Shah, Leidy Lismeris Isenalumhe, Nelli Bejanyan, Aleksandr Lazaryan, Rawan Faramand
Journal: Blood
Blood (2023) 142 (Supplement 1): 2830.
https://doi.org/10.1182/blood-2023-180321
Published: 2023
Journal Articles

Phase II Trial of Reduced-Intensity Fludarabine, Melphalan, and Total Body Irradiation Conditioning Results in Favorable Outcomes with Haploidentical Donor Peripheral Blood Stem Cell Transplant

Hany Elmariah, Jongphil Kim, Asmita Mishra, Rawan Faramand, Lia Perez, Aleksandr Lazaryan, Farhad Khimani, Hien Liu, Jose L. Ochoa-Bayona, Michael Nieder, Nicholas Figura, Timothy J Robinson, Taiga Nishihori, Claudio Anasetti, Joseph A. Pidala, Nelli Bejanyan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4900.
https://doi.org/10.1182/blood-2023-187473
Published: 2023
Journal Articles

JAK2/mTOR Inhibition Fails to Prevent Acute Gvhd Despite Reduced Th1/Th17 Cells: Final Phase II Trial Results

Joseph Pidala, Shernan G. Holtan, Kelly Walton, Jongphil Kim, Hany Elmariah, Asmita Mishra, Nelli Bejanyan, Taiga Nishihori, Farhad Khimani, Lia Perez, Rawan Faramand, Marco Davila, Claudio Anasetti, Daniel Weisdorf, Bruce R Blazar, Jeffrey S Miller, Veronika Bachanova, Najla H El Jurdi, Brian C Betts
Journal: Blood
Blood (2023) 142 (Supplement 1): 2177.
https://doi.org/10.1182/blood-2023-173376
Published: 2023
Journal Articles

Patient-Reported Outcomes of BMT CTN 1703: A Randomized Phase III Study for Gvhd Prophylaxis - a Quality of Life Evaluation

Shernan G. Holtan, Michael J Martens, Monzr M. Al Malki, Yvonne Efebera, Carrie L. Kitko, Ran Reshef, Andrew R. Rezvani, Brian C. Shaffer, Melhem M. Solh, Janny M. Yao, Lyndsey Runaas, Hany Elmariah, Karilyn T. Larkin, Najla H El Jurdi, Mahasweta Gooptu, Alison W Loren, Aric C. Hall, Amin Alousi, Omer Jamy, William Clark, Leslie Kean, Ami S. Bhatt, Miguel-Angel Perales, Kristy Applegate, Juan WU, Eric Liefer, Nancy DiFronzo, Richard J. Jones, Mary M. Horowitz, Deborah Mattila, Mehdi Hamadani, Javier Bolanos-Meade
Journal: Blood
Blood (2023) 142 (Supplement 1): 897.
https://doi.org/10.1182/blood-2023-187859
Published: 2023
Journal Articles

Large-Scale Post-Transplant TCR Deep Sequencing Reveals a Major T Cell Diversity Bottleneck with Post-Transplant Cyclophosphamide with Implications for Both Efficacy and Toxicity: Results of the BMT CTN 1801 Study

Leslie Kean, Steven J Siegel, Joseph T Schmalz, Stephanie A Bien, Danielle Scheffey, Catherine Sanders, Harlan Robins, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung W. Choi, William Clark, Suman r Das, Robert R. Jenq, Richard J. Jones, John Levine, Brent R. Logan, Hemant S. Murthy, Armin Rashidi, Marcie L. Riches, Wael Saber, Karamjeet S. Sandhu, Anthony D. Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian C. Shaffer, Andrew R. Rezvani, Najla El Jurdi, Alison Loren, Mary M. Horowitz, Javier Bolanos-Meade, Shernan G. Holtan, Ami S. Bhatt, Miguel-Angel Perales, Susan DeWolf
Journal: Blood
Blood (2023) 142 (Supplement 1): 475.
https://doi.org/10.1182/blood-2023-188032
Published: 2023
Journal Articles

Post-Transplant Cyclophosphamide Equalizes Clinical Outcomes of Allogeneic Hematopoietic Cell Transplantation across Racial and Ethnic Populations

Teresa Caprice, Wenyi Fan, Jongphil Kim, Rawan Faramand, Asmita Mishra, Lia Perez, Farhad Khimani, Aleksandr Lazaryan, Jose L. Ochoa-Bayona, Hien Liu, Michael D. Jain, Michael Nieder, Claudio Anasetti, Taiga Nishihori, Joseph A. Pidala, Nelli Bejanyan, Hany Elmariah
Journal: Blood
Blood (2023) 142 (Supplement 1): 390.
https://doi.org/10.1182/blood-2023-186738
Published: 2023
Journal Articles

A Novel Composite Endpoint of Toxicity-Free, Progression-Free Survival (TPFS) after CD19-Directed Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Aditi Saha, Razan Mohty, Junmin Whiting, Kristen Flores, Jongphil Kim, Taiga Nishihori, Julio C Chavez, Farhad Khimani, Doris K. Hansen, Fabiana Perna, Hien Liu, Bijal D. Shah, Marian Dam, Muhammad Jaffer, Sepideh Mokhtari, Hany Elmariah, Rawan Faramand, Christina A Bachmeier, Nelli Bejanyan, Frederick L. Locke, Michael D. Jain, Aleksandr Lazaryan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1776.
https://doi.org/10.1182/blood-2023-185117
Published: 2023
Journal Articles

Phase I Trial of Allogeneic Donor Gamma Delta T Cell Infusion Post-Hematopoietic Cell Transplantation, an Interim Safety Report

Nelli Bejanyan, Hany Elmariah, Kayla Reid, Bin Yu, Jongphil Kim, Cheryl Cox, Melissa Lowden, Rawan Faramand, Christopher Cubitt, Hien Liu, Justin Boucher, Jose Alejandro Guevara, David A Sallman, Jeffrey Lancet, Joseph A. Pidala, Kumar Karyampudi, Frederick L. Locke, Claudio Anasetti, Marco Davila
Journal: Blood
Blood (2023) 142 (Supplement 1): 4846.
https://doi.org/10.1182/blood-2023-187058
Published: 2023
Journal Articles

Post-Transplant Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil As the New Standard for Graft-Versus-Host Disease (GVHD) Prophylaxis in Reduced Intensity Conditioning: Results from Phase III BMT CTN 1703

Shernan G Holtan, Mehdi Hamadani, Juan WU, Monzr M. AL Malki, Lyndsey Runaas, Hany Elmariah, Andrew R. Rezvani, Mahasweta Gooptu, Karilyn T. Larkin, Brian C. Shaffer, Najla H El Jurdi, Alison W. Loren, Melhem Solh, Aric C. Hall, Amin M Alousi, Omer H Jamy, Miguel-Angel Perales, Janny M. Yao, Kristy Applegate, Ami S. Bhatt, Leslie S. Kean, Yvonne A. Efebera, Carrie Lynn Kitko, Ran Reshef, William Clark, Nancy L. DiFronzo, Lori Henderson, Richard J. Jones, Eric Liefer, Michael J Martens, Mary M. Horowitz, Javier Bolanos-Meade
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2022-171463
Published: 2022
Journal Articles

Outpatient Treatment with Anti-Sars-Cov-2 Monoclonal Antibodies and Remdesivir for COVID19 Infections Demonstrates Encouraging Outcomes in Hematopoietic Stem Cell Transplant Recipients: A Single-Center Experience

Filip Ionescu, Eloho Ajayi, Aamia Leach, Melissa Alsina, Nelli Bejanyan, Omar Castaneda-Puglianini, Hany Elmariah, Ciara L. Freeman, Doris K. Hansen, Michael D. Jain, Farhad Khimani, Aleksandr Lazaryan, Hien D. Liu, Frederick L. Locke, Bryan McIver, Asmita Mishra, Michael Nieder, Jose Ochoa, Lia Perez, Joseph Pidala, Aliyah Baluch, Olga Klinkova, Rod Quilitz, Taiga Nishihori, Rawan Faramand
Journal: Blood
Blood (2022) 140 (Supplement 1): 10488–10490.
https://doi.org/10.1182/blood-2022-170337
Published: 2022
Journal Articles

Phase I Trial of CD8-Depleted Human Leukocyte Antigen (HLA) Mismatched Unrelated Donor Lymphocyte Infusion (DLI) to Achieve Remissions in Myelodysplastic Syndrome (MDS) and Secondary Acute Myeloid Leukemia (sAML)

Hany Elmariah, Jongphil Kim, Kayla M. Reid, Christopher Cubitt, Andrew Kuykendall, Jeffrey E. Lancet, Rami S. Komrokji, David A. Sallman, Onyee Chan, Kendra Sweet, Albert J Ribickas, Rawan Faramand, Asmita Mishra, Farhad Khimani, Lia Perez, Debra Kessler, Stephanie Dormesy, Joseph Pidala, Claudio Anasetti, Ephraim J. Fuchs, Michael D. Jain, Frederick L. Locke, Marco L. Davila, Nelli Bejanyan, Amy E. DeZern
Journal: Blood
Blood (2022) 140 (Supplement 1): 886–888.
https://doi.org/10.1182/blood-2022-168175
Published: 2022
Journal Articles

Multicenter Pilot Clinical Trial of Enasidenib As Maintenance Therapy after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia (AML) Carrying IDH2 Mutations

Amandeep Salhotra, Nelli Bejanyan, Dongyun Yang, Sally Mokhtari, Monzr M. Al Malki, Karamjeet S. Sandhu, Rawan Faramand, Ibrahim Aldoss, Andrew S. Artz, Ahmed Aribi, Hany Elmariah, Firoozeh Sahebi, Joshua Mansour, Brian J Ball, Vaibhav Agrawal, Ling Li, Vinod A. Pullarkat, Stephen J Forman, Guido Marcucci, Ryotaro Nakamura, Anthony S. Stein
Journal: Blood
Blood (2022) 140 (Supplement 1): 1890–1892.
https://doi.org/10.1182/blood-2022-169964
Published: 2022
Journal Articles

Sirolimus Results in Similar Outcomes to Tacrolimus for Gvhd Prophylaxis after Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide

Hany Elmariah, Salman Otoukesh, Ambuj Kumar, Haris Ali, Shukaib Arslan, Amrita Desai, Amanda Blackmon, Hoda Pourhassan, Taiga Nishihori, Rawan Faramand, Asmita Mishra, Farhad Khimani, Hugo F Fernandez, Aleksandr Lazaryan, Michael Nieder, Lia Perez, Hien D. Liu, Ryotaro Nakamura, Joseph Pidala, Guido Marcucci, Stephen J Forman, Claudio Anasetti, Frederick L. Locke, Nelli Bejanyan, Monzr M. Al Malki
Journal: Blood
Blood (2022) 140 (Supplement 1): 7638–7640.
https://doi.org/10.1182/blood-2022-168400
Published: 2022
Journal Articles

Haploidentical Donor Transplantation with Posttransplantation Cyclophosphamide in Myelodysplastic/Myeloproliferative Neoplasms: A Multi-Institutional Collaboration of 14 Centers

Tania Jain, Hua-Ling Tsai, Hany Elmariah, Pankit Vachhani, Theodoros Karantanos, Sarah A Wall, Lukasz P. Gondek, Asad Bashey, Alla Keyzner, Michael R. Grunwald, Sameem Abedin, Kalyan VG Nadiminti, Madiha Iqbal, Aaron T. Gerds, Auro Viswabandya, Shannon R McCurdy, MHD Monzr M. Al Malki, Ravi Varadhan, Haris Ali, Vikas Gupta, Richard J. Jones, Salman Otoukesh
Journal: Blood
Blood (2022) 140 (Supplement 1): 7731–7733.
https://doi.org/10.1182/blood-2022-157985
Published: 2022
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplant Outcomes in Adults with Inherited Myeloid Malignancies

Caner Saygin, Gregory W. Roloff, Christopher N Hahn, Rakchha Chhetri, Saar Gill, Hany Elmariah, Chetasi Talati, Emma Nunley, Guimin Gao, Aelin Kim, Michael R. Bishop, Satyajit Kosuri, Soma Das, Deepak Singhal, Parvathy Venugopal, Claire Homan, Anna L. Brown, Hamish S Scott, Devendra Hiwase, Lucy A. Godley
Journal: Blood
Blood (2022) 140 (Supplement 1): 10542–10544.
https://doi.org/10.1182/blood-2022-167098
Published: 2022
Journal Articles

Impact of Obesity and Weight-Based Chemotherapy Dosing Adjustments on Outcomes of Allogeneic Hematopoietic Cell Transplant Outcomes for Acute Myeloid Leukemia

Omar Albanyan, Syeda Mahrukh Hussnain Naqvi, Qianxing Mo, Athena Belfon, Eric Gaskill, Taiga Nishihori, Rawan Faramand, Aleksandr Lazaryan, Doris K. Hansen, Farhad Khimani, Asmita Mishra, Michael Nieder, Lia Perez, Hien D. Liu, Joseph Pidala, Claudio Anasetti, Frederick L. Locke, Nelli Bejanyan, Hany Elmariah
Journal: Blood
Blood (2022) 140 (Supplement 1): 7664–7666.
https://doi.org/10.1182/blood-2022-166008
Published: 2022
Journal Articles

Baseline Systemic Inflammatory Markers Interleukin 6 and Ferritin Are Associated with Toxicities and Progression-Free Survival in Multiple Myeloma Patients Treated with Idecabtagene Vicleucel

Doris K. Hansen, Lauren C. Peres, Ciara L. Freeman, Omar Alexis Castaneda Puglianini, Rawan Faramand, Laura B. Oswald, Kayla M. Reid, Gabriel De Avila, Brandon J. Blue, Ariel F. Grajales-Cruz, Jose Ochoa, Alexandria Shrewsbury, Cole T. Powell, Christina Copponex, Krista H. Kottra, Rebecca Gonzalez, Jennifer M. Logue, Farhad Khimani, Hany Elmariah, Michael D. Jain, Taiga Nishihori, Hien D. Liu, Jason Brayer, Ken H. Shain, Rachid Baz, Frederick L. Locke, Melissa Alsina, Marco L. Davila
Journal: Blood
Blood (2022) 140 (Supplement 1): 12778–12780.
https://doi.org/10.1182/blood-2022-158080
Published: 2022
Journal Articles

Outcomes of Acute Myeloid Leukemia Relapsed Post-Allogeneic Hematopoietic Stem Cell Transplant Treated with Hypomethylating Agents and Venetoclax Combination: A Single Center Experience

Filip Ionescu, David A. Sallman, Kendra Sweet, Rami S. Komrokji, Onyee Chan, Andrew Kuykendall, Eric Padron, Rawan Faramand, Nelli Bejanyan, Farhad Khimani, Hany Elmariah, Joseph Pidala, Asmita Mishra, Lia Perez, Taiga Nishihori, Jeffrey E. Lancet
Journal: Blood
Blood (2022) 140 (Supplement 1): 1288–1290.
https://doi.org/10.1182/blood-2022-165661
Published: 2022
Journal Articles

Phase 1/1b Safety Study of Prgn-3006 Ultracar-T in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

David A. Sallman, Hany Elmariah, Kendra Sweet, Asmita Mishra, Cheryl A Cox, Marion Chakaith, Roshanak Semnani, Sheeba Shehzad, Asha Anderson, Helen Sabzevari, Amy Lankford, Onyee Chan, Luis SanchezMolina, Chen Wang, Eric Padron, Andrew Kuykendall, Rami S. Komrokji, Jeffrey E. Lancet, Marco L. Davila, Nelli Bejanyan
Journal: Blood
Blood (2022) 140 (Supplement 1): 10313–10315.
https://doi.org/10.1182/blood-2022-169142
Published: 2022