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Fabiana Perna
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Journal Articles

A Novel Composite Endpoint of Toxicity- and Progression-Free Survival after B-Cell Maturation Antigen (BCMA)-Directed Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Multiple Myeloma

Razan Mohty, Whiting Junmin, Aditi Saha, Jongphil Kim, Taiga Nishihori, Gabriel De Avila, Salvatore Corallo, Marian Dam, Jessica Marin, Hien Liu, Sepideh Mokhtari, Michael D. Jain, Fabiana Perna, Brandon Blue, Ariel F. Grajales-Cruz, Omar Castaneda, Kenneth Shain, Rachid Baz, Ciara Louise L. Freeman, Melissa Alsina, Frederick L. Locke, Doris K. Hansen, Aleksandr Lazaryan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3336.
https://doi.org/10.1182/blood-2023-184406
Published: 2023
Journal Articles

Poor Hematopoietic Reserve at the Time of CD19 CAR T-Cell Infusion Is Associated with Long Term B-Cell Aplasia

Grace Johnson, Kedar Patel, Brian Arciola, Ariel Perez Perez, Anthony Wood, Filip Ionescu, Jennifer M Logue, Omar Albanyan, Hassaan Yasin, Christina A Bachmeier, Kayla Reid, Meghan Menges, Salvatore Corallo, Bijal D. Shah, Julio C Chavez, Farhad Khimani, Taiga Nishihori, Rawan Faramand, Hien Liu, Aleksandr Lazaryan, Kai Rejeski, Marion Subklewe, Fabiana Perna, Marco Davila, Rahul Mhaskar, Frederick L. Locke, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 3512.
https://doi.org/10.1182/blood-2023-185097
Published: 2023
Journal Articles

Impact of Sarcopenia and Subsequent Muscle Loss on Post-CAR T-Cell Outcomes in Relapsed/Refractory Large B-Cell Lymphoma

Khushali Jhaveri, Ram Thapa, Jerald Noble, Dalia Ercan, Pranit Singh, Johannes Fahrmann, Neeraj Y. Saini, Ranran Wu, Jennifer Dennison, Samir Hanash, Robert R. Jenq, Karnav Modi, Nicholas Figura, Julio C Chavez, Bijal D. Shah, Taiga Nishihori, Aleksandr Lazaryan, Farhad Khimani, Christina A Bachmeier, Kenneth Gage, Asmita Mishra, Fabiana Perna, Marco Davila, Kai Rejeski, Marion Subklewe, Frederick L. Locke, Ciara Louise L. Freeman, Nathan Parker, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 2130.
https://doi.org/10.1182/blood-2023-187294
Published: 2023
Journal Articles

A Novel Composite Endpoint of Toxicity-Free, Progression-Free Survival (TPFS) after CD19-Directed Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Aditi Saha, Razan Mohty, Junmin Whiting, Kristen Flores, Jongphil Kim, Taiga Nishihori, Julio C Chavez, Farhad Khimani, Doris K. Hansen, Fabiana Perna, Hien Liu, Bijal D. Shah, Marian Dam, Muhammad Jaffer, Sepideh Mokhtari, Hany Elmariah, Rawan Faramand, Christina A Bachmeier, Nelli Bejanyan, Frederick L. Locke, Michael D. Jain, Aleksandr Lazaryan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1776.
https://doi.org/10.1182/blood-2023-185117
Published: 2023
Journal Articles

Chimeric Antigen Receptor T Cells Targeting LILRB4, an Immunoreceptor Mediating T-Cell Suppression, Are Potently Effective in Multiple Myeloma

Francesco Di Meo, Samuel John, Chengcheng Zhang, Ciara Louise L. Freeman, Fabiana Perna
Journal: Blood
Blood (2023) 142 (Supplement 1): 4804.
https://doi.org/10.1182/blood-2023-182022
Published: 2023
Journal Articles

Cladribine and Cyclophosphamide Lymphodepletion Prior to Axicabtagene Ciloleucel in Relapsed or Refractory Large B-Cell Lymphoma

Filip Ionescu, Bijal D. Shah, Meghan Menges, Kayla Reid, Hanna Bailey, Elizabeth DiMaggio, Rebecca Gonzalez, Christina A Bachmeier, Salvatore Corallo, Luis Cuadrado Delgado, Turab Mohammed, Taiga Nishihori, Farhad Khimani, Aleksandr Lazaryan, Hien Liu, Marco Davila, Fabiana Perna, Julio C Chavez, Frederick L. Locke, Michael D. Jain
Journal: Blood
Blood (2023) 142 (Supplement 1): 4884.
https://doi.org/10.1182/blood-2023-187078
Published: 2023
Journal Articles

How I treat unique and difficult-to-manage cases of CAR T-cell therapy–associated neurotoxicity

Clinical Trials & Observations
Bianca D. Santomasso, Juliane Gust, Fabiana Perna
Journal: Blood
Blood (2023) 141 (20): 2443–2451.
https://doi.org/10.1182/blood.2022017604
Published: 2023
Journal Articles

A Novel Bi-Specific T-Cell Engager Targeting ILT3 Is Potently Effective in Multiple Myeloma

Francesco Di Meo, Anjushree Iyer, Keith Akama, Christina Yu, Rujin Cheng, Annamaria Cesarano, Silvia Marino, Arafat Aljoufi, Rajesh Soni, Julie M Roda, James Sissons, Ly P Vu, Monica L. Guzman, Kun Huang, David G. Roodman, Fabiana Perna
Journal: Blood
Blood (2022) 140 (Supplement 1): 671–672.
https://doi.org/10.1182/blood-2022-167584
Published: 2022
Journal Articles

RNA Deadenylation Subunit CNOT3 Promotes Myeloid Leukemia By Driving Translation of Oncogenic Targets

Maryam Ghashghaei, Marty Yue, Aaremish Arsalan, Giuseppe Bombaci, Sandra Spencer Miko, Haya Shaalan, Glenn Edin, Gregg Morin, Fabiana Perna, Ly P Vu
Journal: Blood
Blood (2022) 140 (Supplement 1): 2962–2963.
https://doi.org/10.1182/blood-2022-163026
Published: 2022
Journal Articles

Emerging Thrombotic Complications in Patients Undergoing Chimeric Antigen Receptor T Cell Therapies

Manuel Ricardo Espinoza-Gutarra, Christopher Schorr, Maya Krishnan, Mohammad Issam Abu Zaid, Rakesh P. Mehta, Fabiana Perna
Journal: Blood
Blood (2022) 140 (Supplement 1): 8530–8531.
https://doi.org/10.1182/blood-2022-164774
Published: 2022
Journal Articles

Mapping the High-Risk Multiple Myeloma Cell Surface Proteome Identifies T-Cell Inhibitory Receptors for Immune Targeting

Francesco Di Meo, Christina Yu, Annamaria Cesarano, Aljoufi Arafat, Silvia Marino, G David Roodman, Hal E. Broxmeyer, Fabiana Perna
Journal: Blood
Blood (2021) 138 (Supplement 1): 265.
https://doi.org/10.1182/blood-2021-147483
Published: 2021
Journal Articles

Safety and Efficacy Trial of Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells (HPCs) for Globin Gene Transfer in Patients with Sickle Cell Disease

Farid Boulad, MD, Tsiporah B. Shore, MD, Koen Van Besien, MD PhD, Danielle Guarneri, June Greenberg, RN, Caterina Minniti, MD, Sylvie wiener Fedus, Fabiana Perna, MD, Xiuyan Wang, PhD, Isabelle Riviere, PhD, Michel Sadelain, MD PhD, Patricia Shi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3531.
https://doi.org/10.1182/blood.V130.Suppl_1.3531.3531
Published: 2017
Journal Articles

Systematic Combinatorial Chimeric Antigen Receptor Therapies to AML

Fabiana Perna, MD, Samuel Berman, Rajesh K Soni, PhD, Jorge Mansilla-Soto, PhD, Justin Eyquem, PhD, Mohamad Hamieh, PhD, Ronald C Hendrickson, PhD, Cameron Brennan, MD, Michel Sadelain, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 856.
https://doi.org/10.1182/blood.V130.Suppl_1.856.856
Published: 2017
Journal Articles

Probing the AML Surfaceome for Chimeric Antigen Receptor (CAR) Targets

Fabiana Perna, MDPhD, Samuel Berman, Jorge Mansilla-Soto, PhD, Mohamad Hamieh, PhD, Rupa Juthani, MD, Rajesh Soni, PhD, Justin Eyquem, PhD, Ronald Hendrickson, PhD, Cameron Brennan, MD, Michel Sadelain, MD PhD
Journal: Blood
Blood (2016) 128 (22): 526.
https://doi.org/10.1182/blood.V128.22.526.526
Published: 2016
Journal Articles

PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis

Fan LIU, PhD, Guoyan Cheng, PhD, Fabiana Perna, MD PhD, Xu Haiming, PhD, Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Stephen Nimer, MD
Journal: Blood
Blood (2014) 124 (21): 4335.
https://doi.org/10.1182/blood.V124.21.4335.4335
Published: 2014
Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD
Journal: Blood
Blood (2012) 120 (21): 2296.
https://doi.org/10.1182/blood.V120.21.2296.2296
Published: 2012
Journal Articles

IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment

Ibrahim Boussaad, PhD, Emily K Dolezal, Fabiana Perna, MD, Stephen D Nimer, MD, Eirini P Papapetrou, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 174.
https://doi.org/10.1182/blood.V120.21.174.174
Published: 2012
Journal Articles

ASXL1 Mutations Promote Myeloid Transformation Through Inhibition of PRC2-Mediated Gene Repression

Omar Abdel-Wahab, MD, Mazhar Adli, PhD, Lindsay Saunders, B.Sc., Jie Gao, PhD, Alan H. Shih, MD, PhD, Suveg Pandey, B.Sc., Jake Jaffe, PhD, Xinyang Zhao, PhD, Fabiana Perna, MD, Martin Carroll, MD, Ari Melnick, MD, Stephen D. Nimer, MD, Iannis Aifantis, PhD, Bradley Bernstein, Ross L Levine, MD
Journal: Blood
Blood (2011) 118 (21): 405.
https://doi.org/10.1182/blood.V118.21.405.405
Published: 2011
Journal Articles

Targeting a Novel Epigenetic Silencing Mechanism to Efficiently Upregulate Fetal Globin Gene Expression

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, Ruben Hoya-Arias, PhD, Xinyang Zhao, PhD, Eirini P. Papapetrou, MD, PhD, Michel Sadelain, MD, PhD, Stephen D. Nimer, MD
Journal: Blood
Blood (2011) 118 (21): 352.
https://doi.org/10.1182/blood.V118.21.352.352
Published: 2011
Journal Articles

Methylation of RUNX1 by the Nuclear PRMT5/COPR5 Complex Regulates Its Cellular Location in Leukemia Cells,

Xinyang Zhao, Ph.D., Ly P. Vu, Fabiana Perna, MD, Fan Liu, MD, Hao Xu, Stephen Nimer
Journal: Blood
Blood (2011) 118 (21): 3403.
https://doi.org/10.1182/blood.V118.21.3403.3403
Published: 2011