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Journal Articles

Safety and Efficacy of Standard of Care Ciltacabtagene Autoleucel for Relapsed/Refractory Multiple Myeloma

Clinical Trials & Observations
Surbhi Sidana, Krina K. Patel, Lauren C Peres, Radhika Bansal, Mehmet Hakan Kocoglu, Leyla Shune, Shebli Atrash, Kinaya Smith, Shonali Midha, Christopher J Ferreri, Binod Dhakal, Danai Dima, Patrick Costello, Charlotte Wagner, Ran Reshef, Hitomi Hosoya, Lekha Mikkilineni, Djordje Atanackovic, Saurabh Chhabra, Ricardo D Parrondo, Omar Nadeem, Hashim Mann, Nilesh Kalariya, Vanna Hovanky, Gabriel DeAvila, Ciara L Freeman, Frederick L Locke, Melissa Alsina, Sandy Wong, Megan M Herr, Myo Htut, Joseph P. McGuirk, Douglas W Sborov, Jack Khouri, Thomas Martin, Murali Janakiram, Yi Lin, Doris K Hansen
Journal: Blood
Blood blood.2024025945.
https://doi.org/10.1182/blood.2024025945
Published: 2024
Includes: Supplemental data
Journal Articles

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

Clinical Trials & Observations
Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis Ayuk, Chantiya Chanswangphuwana, Hannah K. Choe, Matthias Eder, Aaron M. Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Monzr M. Al Malki, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, Ryotaro Nakamura, John E. Levine, James L. M. Ferrara
Journal: Blood
Blood (2024) 144 (9): 1010–1021.
https://doi.org/10.1182/blood.2024025106
Published: 2024
Includes: Supplemental data
Journal Articles

High efficacy of CD19 CAR T cells in patients with transformed Waldenström macroglobulinemia

Clinical Trials & Observations
Eric Durot, Damien Roos-Weil, Adrien Chauchet, Justine Decroocq, Roberta Di Blasi, Thomas Gastinne, Hedi Bensaber, Morgane Cheminant, Caroline Jacquet, Stéphanie Guidez, François-Xavier Gros, Emmanuel Bachy, Arthur Coste, Pascale Cony-Makhoul, Steven P. Treon, Alain Delmer, Ran Reshef, Steven Le Gouill, Jorge J. Castillo, Roch Houot
Journal: Blood
Blood (2024) 143 (26): 2804–2807.
https://doi.org/10.1182/blood.2024024452
Published: 2024
Includes: Supplemental data
Journal Articles

Three-year follow-up analysis of axicabtagene ciloleucel in relapsed/refractory indolent non-Hodgkin lymphoma (ZUMA-5)

Clinical Trials & Observations
Sattva S. Neelapu, Julio C. Chavez, Alison R. Sehgal, Narendranath Epperla, Matthew Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G. Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph Rosenblatt, Ronald Korn, Weixin Peng, Christine Lui, Jacob Wulff, Rhine Shen, Soumya Poddar, A. Scott Jung, Harry Miao, Sara Beygi, Caron A. Jacobson
Journal: Blood
Blood (2024) 143 (6): 496–506.
https://doi.org/10.1182/blood.2023021243
Published: 2024
Includes: Supplemental data
Journal Articles

Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1–mediated immune suppression during GVHD

Ying Wang, Shan He, Gennaro Calendo, Tien Bui, Yuanyuan Tian, Che Young Lee, Yan Zhou, Xin Zhao, Ciril Abraham, Wenbin Mo, Mimi Chen, Ruqayyah Sanders-Braggs, Jozef Madzo, Jean-Pierre Issa, Elizabeth O. Hexner, David L. Wiest, Ran Reshef, Hai-Hui Xue, Yi Zhang
Journal: Blood
Blood (2024) 143 (2): 166–177.
https://doi.org/10.1182/blood.2023021126
Published: 2024
Includes: Supplemental data
Journal Articles

The MAGIC Algorithm Probability Predicts Long-Term Outcomes and Treatment Response to Second-Line Therapy for Acute Gvhd

Zachariah Defilipp, Haesook T. Kim, Nikolaos Spyrou, Steven Kowalyk, Gilbert Eng, Rahnuma Beheshti, Janna Baez, Francis A. Ayuk, Hannah Choe, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Muna Qayed, Ran Reshef, Ingrid Vasova, Robert Zeiser, Rachel Young, James L.M. Ferrara, Ryotaro Nakamura, John Levine, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 3576.
https://doi.org/10.1182/blood-2023-182300
Published: 2023
Journal Articles

Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma: 4-Year Follow-up from the Phase 2 ZUMA-5 Trial

Sattva S. Neelapu, Julio C. Chavez, Alison R Sehgal, Narendranath Epperla, Matthew L. Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph D. Rosenblatt, Weixin Peng, Christine Lui, Jacob Wulff, Rhine R. Shen, Soumya Poddar, Andrew Lee, Harry Miao, Olga Nikolajeva, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4868.
https://doi.org/10.1182/blood-2023-174914
Published: 2023
Journal Articles

Itacitinib for the Prevention of Immune Effector Cell Therapy-Associated Cytokine Release Syndrome: Results from the Phase 2 Incb 39110-211 Placebo-Controlled Randomized Cohort

Matthew J. Frigault, Richard T Maziarz, Jae H. Park, Aleksandr Lazaryan, Nirav N. Shah, Jakub Svoboda, Lazaros J. Lekakis, Ran Reshef, Christine L Phillips, Lea M Burke, Jing Lei, Rodica Morariu-Zamfir, John F. DiPersio
Journal: Blood
Blood (2023) 142 (Supplement 1): 356.
https://doi.org/10.1182/blood-2023-180205
Published: 2023
Journal Articles

The Effect of Preemptive Rituximab Treatment in Patients with EBV Viremia after Solid Organ Transplantation on the Development of Post-Transplant Lymphoproliferative Disorder

Evelyn H. Orlando, Patrick Gould, Brian Cuzzo, Maegan Ford, Yuxuan Chen, Alexander Sanjurjo, Benjamin May, Demetra Tsapepas, Rebecca J. Leeman-Neill, Govind Bhagat, Geoffrey Dube, Heather Morris, Selim Arcasoy, Farhana Latif, Mercedes Martinez, Marcus Pereira, Andrew H. Lipsky, Ahmed Sawas, Ran Reshef, Barbara Pro, Hua-Jay J. Cherng, Jennifer E. Amengual
Journal: Blood
Blood (2023) 142 (Supplement 1): 990.
https://doi.org/10.1182/blood-2023-177823
Published: 2023
Journal Articles

Alternative Lymphodepletion Strategies Lead to Similar Response Rates and Toxicities in Standard-of-Care BCMA-Directed CAR-T Therapy in Relapsed Refractory Multiple Myeloma

Shonali Midha, Ashwath Gurumurthi, Patrick Costello, Robert A. Redd, Ciara Louise L. Freeman, Omar Castaneda, Rebecca Gonzalez, Filip Ionescu, Mahmoud Gaballa, Nilesh Kalariya, Jack Khouri, Danai Dima, Mehmet H. Kocoglu, Douglas Sborov, Charlotte B Wagner, Shebli Atrash, Peter M. Voorhees, Hamza Hashmi, James A Davis, Peter A. Forsberg, Joseph P McGuirk, Leyla Shune, Megan Herr, Ran Reshef, Yi Lin, Myo Htut, Thomas Martin, Surbhi Sidana, Doris K. Hansen, Omar Nadeem, Krina K. Patel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3499.
https://doi.org/10.1182/blood-2023-187565
Published: 2023
Journal Articles

Patient-Reported Outcomes of BMT CTN 1703: A Randomized Phase III Study for Gvhd Prophylaxis - a Quality of Life Evaluation

Shernan G. Holtan, Michael J Martens, Monzr M. Al Malki, Yvonne Efebera, Carrie L. Kitko, Ran Reshef, Andrew R. Rezvani, Brian C. Shaffer, Melhem M. Solh, Janny M. Yao, Lyndsey Runaas, Hany Elmariah, Karilyn T. Larkin, Najla H El Jurdi, Mahasweta Gooptu, Alison W Loren, Aric C. Hall, Amin Alousi, Omer Jamy, William Clark, Leslie Kean, Ami S. Bhatt, Miguel-Angel Perales, Kristy Applegate, Juan WU, Eric Liefer, Nancy DiFronzo, Richard J. Jones, Mary M. Horowitz, Deborah Mattila, Mehdi Hamadani, Javier Bolanos-Meade
Journal: Blood
Blood (2023) 142 (Supplement 1): 897.
https://doi.org/10.1182/blood-2023-187859
Published: 2023
Journal Articles

Initial Results of a Phase 1 Trial of TSC-100 and TSC-101, Engineered T Cell Therapies That Target Minor Histocompatibility Antigens to Prevent Relapse after Allogeneic Hematopoietic Cell Transplantation

Monzr M. Al Malki, Alla Keyzner, Hyung Chan Suh, Aasiya Matin, Erica Buonomo, Yun Wang, Nina Abelowitz, Jim Murray, Gavin Macbeath, Debora Barton, Shrikanta Chattopadhyay, Ran Reshef
Journal: Blood
Blood (2023) 142 (Supplement 1): 2090.
https://doi.org/10.1182/blood-2023-187355
Published: 2023
Journal Articles

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Nikolaos Spyrou, Yu Akahoshi, Steven Kowalyk, George Morales, Rahnuma Beheshti, Paibel Aguayo-Hiraldo, MHD Monzr Al Malki, Francis Ayuketang Ayuk, Peter Bader, Janna Baez, Alexandra Capellini, Hannah Choe, Zachariah Defilipp, Matthias Eder, Gilbert Eng, Aaron Etra, Sigrun Gleich, Stephan Grupp, Elizabeth Hexner, Matthias Hoepting, William J. Hogan, Stelios Kasikis, Nikolaos Katsivelos, Carrie L. Kitko, Sabrina Kraus, Deukwoo Kwon, Pietro Merli, Joseph Portelli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Ingrid Vasova, Matthias Woelfl, Kitsada Wudhikarn, Rachel Young, Ernst Holler, Yi-Bin Chen, Ryotaro Nakamura, John Levine, James L.M. Ferrara
Journal: Blood
Blood (2023) 142 (Supplement 1): 779.
https://doi.org/10.1182/blood-2023-172955
Published: 2023
Journal Articles

CD19-Targeting CAR T-Cell Therapy in Transformed Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma: A Descar-T and US Collaborative Study

Eric Durot, Damien Roos-Weil, Adrien Chauchet, Justine Decroocq, Roberta Di Blasi, Thomas Gastinne, Hedi Bensader, Morgane Cheminant, Caroline Jacquet, Stephanie Guidez, François-Xavier Gros, Emmanuel Bachy, Pascale Cony-Makhoul, Steven P Treon, Alain Jacques Delmer, Ran Reshef, Steven Le Gouill, Jorge J. Castillo, Roch Houot
Journal: Blood
Blood (2023) 142 (Supplement 1): 616.
https://doi.org/10.1182/blood-2023-173988
Published: 2023
Journal Articles

Methylated Whole Genome Cell-Free DNA Sequencing before Chimeric Antigen Receptor T-Cell Therapy for Large B-Cell Lymphoma Predicts Treatment Outcomes

Hua-Jay J. Cherng, Xiaojing Yang, Ryan Yancey, Christian A Gordillo, Ted B. Piorczynski, Hei T. Chan, Kenneth N. Ofori, Govind Bhagat, Andrea Califano, Barbara Pro, Keith Booher, Jennifer E. Amengual, Ran Reshef, Abu A. I. Sina
Journal: Blood
Blood (2023) 142 (Supplement 1): 4371.
https://doi.org/10.1182/blood-2023-178376
Published: 2023
Journal Articles

Flares of Acute Graft-Versus-Host Disease: Mount Sinai Acute Gvhd International Consortium (MAGIC) Study

Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Udomsak Bunworasate, Hannah Choe, Matthias Eder, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Evelyn Ullrich, Ingrid Vasova, Matthias Woelfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John Levine, Ryotaro Nakamura
Journal: Blood
Blood (2023) 142 (Supplement 1): 776.
https://doi.org/10.1182/blood-2023-181900
Published: 2023
Journal Articles

Efficacy and Safety of Idecabtagene Vicleucel (ide-cel) in Patients with Clinical High-Risk Newly Diagnosed Multiple Myeloma (NDMM) with an Inadequate Response to Frontline Autologous Stem Cell Transplantation (ASCT): KarMMa-2 Cohort 2c Extended Follow-up

Madhav V. Dhodapkar, Melissa Alsina, Jesus G. Berdeja, Krina K. Patel, Shambavi Richard, Ravi Vij, Xavier Leleu, Daniel N. Egan, P. Leif Bergsagel, Ran Reshef, Saad Z Usmani, Anna Truppel-Hartmann, Debashree Basudhar, Ethan Thompson, Xirong Zheng, Laurie Eliason, Xiaobo Zhong, Chiara Greggio, Sinhan Tran, Maria Chaudhry, Marlene J. Carrasco-Alfonso, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2101.
https://doi.org/10.1182/blood-2023-173970
Published: 2023
Journal Articles

Characteristics of Alloreactive T-Cell Clones That Predict Early Development of Acute GvHD Following Allogeneic HCT

Ximi Kevin Wang, Ajna Uzuni, Kirubel Belay, David W Harle, Christian A Gordillo, Rodney J Macedo, Shami Chakrabarti, Lingting Shi, Michael Pressler, Joshua Fuller, Elham Azizi, Ran Reshef
Journal: Blood
Blood (2023) 142 (Supplement 1): 2042.
https://doi.org/10.1182/blood-2023-187932
Published: 2023
Journal Articles

Reduced Early Mortality with Daratumumab-Based Frontline Therapy in Systemic AL Amyloidosis- Experience from the Columbia Amyloidosis Multidisciplinary Program

Rajshekhar Chakraborty, Divaya Bhutani, Markus Mapara, Ran Reshef, Mathew S Maurer, Jai Radhakrishnan, Suzanne Lentzsch
Journal: Blood
Blood (2023) 142 (Supplement 1): 4780.
https://doi.org/10.1182/blood-2023-187214
Published: 2023
Journal Articles

Post CAR-T Peripheral Lymphocytosis and Its Kinetics Are a Potential Biomarker for Response and Immune Mediated Toxicities

Mateo Mejia Saldarriaga, Caitlin Unkenholz, Joshua A Fein, Jorge Monge, Cara Rosenbaum, Roger Pearse, Markus Mapara, Giorgio Inghirami, Suzanne Lentzsch, Ran Reshef, Ruben Niesvizky, Mark Bustoros
Journal: Blood
Blood (2023) 142 (Supplement 1): 3341.
https://doi.org/10.1182/blood-2023-187832
Published: 2023