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Journal Articles

Single Cell Transcriptomics of Bronchiolitis Obliterans Syndrome

Patrick Mellors, Ana Nottingham, Maksim Shestov, Maria Basil, Saar Gill
Journal: Blood
Blood (2023) 142 (Supplement 1): 4797.
https://doi.org/10.1182/blood-2023-180062
Published: 2023
Journal Articles

Molecular Attributes of CAR T Cell Fitness in Patients with Chronic Lymphocytic Leukemia

Xiaoli Mi, Dennis Yuan, Rebecca Murray, Jani Huuhtanen, Beatrice Zhang, Jean Quentin, Olga Shestova, David L. Porter, Satu Mustjoki, Saar Gill, Dan A. Landau
Journal: Blood
Blood (2023) 142 (Supplement 1): 3452.
https://doi.org/10.1182/blood-2023-187956
Published: 2023
Journal Articles

Comparing Cairo Bishop and Howard Criteria for Identifying Clinically Meaningful Tumor Lysis Syndrome Among Acute Myeloid Leukemia Patients Treated with Venetoclax and Hypomethylating Agents: A Single Center Experience

Margaret Rowe, Daria V Babushok, Martin Carroll, Alison Carulli, Noelle V. Frey, Saar Gill, Elizabeth O Hexner, Rebecca Hirsh, Nasheed Hossain, Catherine Lai, Alison W Loren, Selina M Luger, Ivan Maillard, Shannon R McCurdy, Andrew H Matthews, Mary Ellen Martin, Vikram R Paralkar, Alexander Perl, David L. Porter, Keith W Pratz, Edward A. Stadtmauer, Ximena Jordan Bruno
Journal: Blood
Blood (2023) 142 (Supplement 1): 5095.
https://doi.org/10.1182/blood-2023-186978
Published: 2023
Journal Articles

Evolving Racial/Ethnic Disparities in AML Survival in the Novel Therapy Era: Real-World Evidence of Improved Survival in Older Patients with the Largest Improvement in Non-Hispanic Black Patients

Xin Wang, Phyllis Gimotty, Andrew H Matthews, Ronac Mamtani, Selina M Luger, Elizabeth O Hexner, Daria V Babushok, Shannon R McCurdy, Noelle V. Frey, Ximena Jordan Bruno, David L. Porter, Saar Gill, Mary Ellen Martin, Vikram R Paralkar, Ivan Maillard, Alison W Loren, Alexander Perl, Keith W Pratz, Kelly D. Getz, Catherine Lai
Journal: Blood
Blood (2023) 142 (Supplement 1): 955.
https://doi.org/10.1182/blood-2023-180185
Published: 2023
Journal Articles

Cytokine Release Syndrome Results in Reduced AML Killing By CD123 CAR T Cells

Anand S Bhagwat, Leonel Torres, Olga Shestova, Maksim Shestov, Noelle V. Frey, Elizabeth O Hexner, Selina M Luger, Alison W Loren, Mary Ellen Martin, Shannon R McCurdy, Alexander Perl, Edward A. Stadtmauer, James K. Mangan, Jennifer Brogdon, Joseph A Fraietta, Wei-Ting Hwang, Don L. Siegel, Saad S. Kenderian, David L. Porter, Carl June, Saar Gill
Journal: Blood
Blood (2023) 142 (Supplement 1): 217.
https://doi.org/10.1182/blood-2023-182104
Published: 2023
Journal Articles

Hypomethylating Agents Are Associated with High Rates of Hematologic Toxicity in Patients with Secondary MDS/AML That Develops after Acquired Aplastic Anemia

Matthew P Connor, Neeharika Prathapa, Noelle V. Frey, Saar Gill, Elizabeth O Hexner, Ximena Jordan Bruno, Catherine Lai, Alison W Loren, Selina M Luger, Andrew H Matthews, Shannon R McCurdy, Alexander Perl, David L. Porter, Arlene Zeringue, Joseph H. Oved, Timothy S Olson, Keith W Pratz, Daria V Babushok
Journal: Blood
Blood (2023) 142 (Supplement 1): 2720.
https://doi.org/10.1182/blood-2023-179383
Published: 2023
Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Journal: Blood
Blood (2023) 142 (Supplement 1): 100.
https://doi.org/10.1182/blood-2023-184867
Published: 2023
Journal Articles

Frail and Pre-Frail Older Adults with Acute Myeloid Leukemia Have Inferior Survival Due to Higher Rates of Disease-Related Deaths

Ashley D Hadjis, Griffin W White, Christopher Catania, Noelle V. Frey, Saar Gill, Elizabeth O Hexner, Ximena Jordan Bruno, Catherine Lai, Andrew H Matthews, Mary Ellen Martin, Daria V Babushok, Alexander Perl, David L. Porter, Alison W Loren, Keith W Pratz, Selina M Luger, Shannon R McCurdy
Journal: Blood
Blood (2023) 142 (Supplement 1): 376.
https://doi.org/10.1182/blood-2023-188978
Published: 2023
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplant Outcomes in Adults with Inherited Myeloid Malignancies

Caner Saygin, Gregory W. Roloff, Christopher N Hahn, Rakchha Chhetri, Saar Gill, Hany Elmariah, Chetasi Talati, Emma Nunley, Guimin Gao, Aelin Kim, Michael R. Bishop, Satyajit Kosuri, Soma Das, Deepak Singhal, Parvathy Venugopal, Claire Homan, Anna L. Brown, Hamish S Scott, Devendra Hiwase, Lucy A. Godley
Journal: Blood
Blood (2022) 140 (Supplement 1): 10542–10544.
https://doi.org/10.1182/blood-2022-167098
Published: 2022
Journal Articles

Ameli-01: A Phase I Trial of UCART123v1.2, an Anti-CD123 Allogeneic CAR-T Cell Product, in Adult Patients with Relapsed or Refractory (R/R) CD123+ Acute Myeloid Leukemia (AML)

David A. Sallman, Daniel J. DeAngelo, Naveen Pemmaraju, Shira Dinner, Saar Gill, Rebecca L. Olin, Eunice S. Wang, Marina Konopleva, Eileen Stark, Ana Korngold, Asifa Haider, Kate Backhouse, Carolyn Figliola, Daniel J. Lee, Mark G. Frattini, Carrie Brownstein, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 2371–2373.
https://doi.org/10.1182/blood-2022-169928
Published: 2022
Journal Articles

Targeting CD38 in T-ALL Upregulates the Targetable Polyamine Metabolism Pathway

Caroline Diorio, Tiffaney L. Vincent, Tori Fuller, Rawan Shraim, Tina Glisovic-Aplenc, Theresa Ryan, Kimberly Veliz, Haley Newman, Gerald Wertheim, Hamid Bassiri, Annette Vu, Michael Hogarty, Carl H June, Stephan A. Grupp, Sarah K Tasian, Richard Aplenc, Saar Gill, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 10285–10286.
https://doi.org/10.1182/blood-2022-167893
Published: 2022
Journal Articles

Selective Support of CAR-T Cell Therapies By Cis-Targeted IL-2 or IL-21 Cytokines Results in Enhanced Anti-Tumor Activity

Sara Sleiman, Nathan D Mathewson, Feng Shen, Kelly Moynihan, Wei Chen, Paul Bessette, Chris Kimberlin, Danielle Pappas, Terrence Park, Andy Yeung, Ivana Djuretic, Saar Gill
Journal: Blood
Blood (2022) 140 (Supplement 1): 10259–10260.
https://doi.org/10.1182/blood-2022-168411
Published: 2022
Journal Articles

Proteotranscriptomic Strategy to Discover Acute Myeloid Leukemia Immunotherapy Targets

Lusha Cao, Yang Xu, Tina Glisovic-Aplenc, Kevin Nestler, Saar Gill, Kathrin M. Bernt, Benjamin A Garcia, Hossein Fazelinia, Lingyu Guan, Yi Xing, Richard Aplenc
Journal: Blood
Blood (2022) 140 (Supplement 1): 3425–3426.
https://doi.org/10.1182/blood-2022-167378
Published: 2022
Journal Articles

Fried's Frailty Phenotype Predicts Mortality and Survival for Newly Diagnosed Older Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Cristian C. Taborda, Shannon H Gier, Avery W Stivale, Alexander E. Perl, Saar Gill, Daria V. Babushok, Elizabeth O. Hexner, Noelle V. Frey, Catherine Lai, Ximena Jordan Bruno, Mary Ellen Martin, Ivan Maillard, David L. Porter, Alison W. Loren, Keith W. Pratz, Selina M. Luger, Phyllis A. Gimotty, Shannon R. McCurdy
Journal: Blood
Blood (2022) 140 (Supplement 1): 10825–10827.
https://doi.org/10.1182/blood-2022-169924
Published: 2022
Journal Articles

G-CSF Mobilized Apheresis As an Alternative Source of CAR T-Cells

Katherine D Cummins, Arjun Gupta, Ofrat Beyar-Katz, Ye Li, Paramita Chatterjee, Linda Kippner, Olga Shestova, Monika A Eiva, January Salas-Mckee, Carolyn Yeago, Krishnendu Roy, Saar Gill
Journal: Blood
Blood (2022) 140 (Supplement 1): 7415–7416.
https://doi.org/10.1182/blood-2022-165916
Published: 2022
Journal Articles

Epitope Editing in Hematopoietic Cells Enables CD45-Directed Immune Therapy

Nils Wellhausen, Austin K Rennels, Stefanie Lesch, Sangya Agarwal, Brooke Charria, Grace Choi, Regina M Young, Christopher Garcia, Carl H June, Saar Gill
Journal: Blood
Blood (2022) 140 (Supplement 1): 862–864.
https://doi.org/10.1182/blood-2022-158684
Published: 2022
Journal Articles

Real World Effectiveness of "7 + 3" Intensive Chemotherapy Vs Venetoclax and Hypomethylating Agent for Initial Therapy in Adult Acute Myeloid Leukemia

Andrew Matthews, Alexander E. Perl, Selina M. Luger, Saar Gill, Catherine Lai, David L. Porter, Sarah Skuli, Ximena Jordan Bruno, Craig W. Freyer, Alison Carulli, Martin P. Carroll, Daria V. Babushok, Noelle V. Frey, Elizabeth O. Hexner, Mary Ellen Martin, Shannon R. McCurdy, Edward A. Stadtmauer, Alison W. Loren, Vikram R Paralkar, Ivan Maillard, Keith W. Pratz
Journal: Blood
Blood (2022) 140 (Supplement 1): 1022–1024.
https://doi.org/10.1182/blood-2022-168036
Published: 2022
Journal Articles

CART22-65s Co-Administered with huCART19 in Adult Patients with Relapsed or Refractory ALL

Noelle V Frey, Saar Gill, Wei-Ting Hwang, Selina M. Luger, Mary Ellen Martin, Shannon R. McCurdy, Alison W. Loren, Keith W. Pratz, Alexander E. Perl, Julie Barber-Rotenberg, Amy Marshall, Marco Ruella, Simon F Lacey, Joseph Fraietta, Andrew Fesnak, Megan O'brien, Theresa Schanne, Jennifer L Brogdon, Boris Engels, Bruce L Levine, Carl H June, David L Porter, Elizabeth O. Hexner
Journal: Blood
Blood (2021) 138 (Supplement 1): 469.
https://doi.org/10.1182/blood-2021-153955
Published: 2021
Journal Articles

Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells

J. Joseph Melenhorst, Gregory M Chen, Meng Wang, David L. Porter, Peng Gao, Shovik Bandyopadhyay, Iulian Pruteanu-Malinici, Christopher L Nobles, Sayantan Maji, Noelle V Frey, Saar Gill, Lifeng Tian, Irina Kulikovskaya, Megan M Davis, Joseph A Fraietta, Jennifer L Brogdon, Regina Young, David E Ambrose, Anne Chew, Bruce L Levine, Don L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F Lacey, Kai Tan, Carl H June
Journal: Blood
Blood (2021) 138 (Supplement 1): 166.
https://doi.org/10.1182/blood-2021-152664
Published: 2021
Journal Articles

Antigen Glycosylation Is a Central Regulator of CAR T Cell Efficacy

Amanda Heard, Mehmet Emrah Selli, John Lattin, Jack Landmann, Jufang Chang, Helen Ha, Balraj Doray, Marco Ruella, Saar Gill, Katharina E. Hayer, Matthew D. Weitzman, Abby M. Green, Regina Fluhrer, Nathan Singh
Journal: Blood
Blood (2021) 138 (Supplement 1): 1721.
https://doi.org/10.1182/blood-2021-146651
Published: 2021