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Selina Luger
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Journal Articles

Prospective study of patient-reported depression, and cognitive and functional impairment, and impact on survival and induction mortality in fit adults age ≥60 years receiving intensive chemotherapy (IC) for Acute Myeloid Leukemia (AML): Prospective geriatric assessment (GA) report from ECOG-ACRIN (EA) E2906 randomized study

Free
James Foran, Li Chen, Selina Luger, Zhuoxin Sun, Heidi Klepin, Catherine Lai, David Claxton, Hillard Lazarus, Daniel Arber, Jacob Rowe, Elisabeth Paietta, Janis Racevskis, Francine Garrett-Bakelman, Yanming Zhang, Jessica Altman, Aref Al-Kali, Hong Zheng, Keith Pratz, Kristen O'Dwyer, Edward Broun, Bayard Powell, John Godwin, Yishai Ofran, Efrat Dotan, Mark Litzow, Martin Tallman, Lynne Wagner
Journal: Blood
Blood (2025) 146 (Supplement 1): 882.
https://doi.org/10.1182/blood-2025-882
Published: 2025
Journal Articles

Phase II Results of ECOG-ACRIN EA9152: A multicenter study of liposomal vincristine (L-VCR) or vincristine sulfate (VCR) and venetoclax (VEN) in relapsed or refractory acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL)

Free
Neil Palmisiano, Juwhei Lee, David Claxton, Elisabeth Paietta, Nikolai Podoltsev, Jae Park, Dale Schaar, Jonathan Webster, Selina Luger, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1577.
https://doi.org/10.1182/blood-2025-1577
Published: 2025
Journal Articles

Impact of therapy delays on outcomes in adults with BCR::ABL1 negative b-lineage acute lymphoblastic leukemia (ALL) in the ECOG-ACRIN E1910 trial randomized to conventional chemotherapy +/- blinatumomab

Free
Bhavana Bhatnagar, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1549.
https://doi.org/10.1182/blood-2025-1549
Published: 2025
Journal Articles

Longitudinal genomic and cytogenetic dynamics in myelodysplastic syndromes (MDS): Insights into clonal evolution and disease progression

Free
Varsha Singh, Rebecca Ramesh, Eesha Balar, Priya Velu, Roopsha Bandopadhyay, Michael Bowman, Safoora Deihimi, Jonathan Belman, Selina Luger, Andrew Matthews, Martin Carroll, Jennifer Morrissette, Sarah Skuli, Robert Bowman
Journal: Blood
Blood (2025) 146 (Supplement 1): 5635.
https://doi.org/10.1182/blood-2025-5635
Published: 2025
Journal Articles

Genomic determinants of treatment outcome and identification of a new genomic subset of adult acute lymphoblastic leukemia from the ECOG-ACRIN E1910 randomized phase III trial

Free
Xiaoming Zhong, Kathryn Roberts, Lindsey Montefiori, Zhuoxin Sun, Huimei Wei, Petri Polonen, Ti-Cheng Chang, Wenchao Zhang, Shaohua Lei, Evadnie Rampersaud, Yiping Fan, Gang Wu, Ryan Mattison, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Martin Tallman, Jun J. Yang, Elisabeth Paietta, Selina Luger, Mark Litzow, Charles Mullighan
Journal: Blood
Blood (2025) 146 (Supplement 1): 31.
https://doi.org/10.1182/blood-2025-31
Published: 2025
Journal Articles

Age-ing study: A prospective evaluation of geriatric, patient-reported and frailty assessments to predict outcomes in older adults with acute myeloid leukemia

Free
Catherine Lai, Thomas Greenwood, E. Paul Wileyto, Nisha Singh, Ashlena Livingston, Amanda Lopez, Selina Luger, Alexander Perl, Ximena Jordan Bruno, Elizabeth Hexner, Shannon McCurdy, Saar Gill, Gary Okano, Ali McBride, Carmelo Alonso, Keith Pratz
Journal: Blood
Blood (2025) 146 (Supplement 1): 2843.
https://doi.org/10.1182/blood-2025-2843
Published: 2025
Journal Articles

Bone marrow biopsy characteristics at nadir after intensive induction therapy do not predict outcomes in acute myeloid leukemia (AML): An analysis of ECOG-ACRIN clinical trials

Free
Douglas Tremblay, Li Chen, Zhuoxin Sun, Chezi Ganzel, Hugo Fernandez, James Foran, Daniel Arber, Hillard Lazarus, Yanming Zhang, Elisabeth Paietta, John Bennett, Jacob Rowe, Mark Litzow, Martin Tallman, Ehab Atallah, Selina Luger
Journal: Blood
Blood (2025) 146 (Supplement 1): 871.
https://doi.org/10.1182/blood-2025-871
Published: 2025
Journal Articles

Inferior survival in black AML patients treated with intensive chemotherapy in ECOG-ACRIN clinical trials is independent of cytogenetic profiles

Free
Shella Saint Fleur-Lominy, Li Chen, Zhuoxin Sun, Francine Garrett-Bakelman, Mihir Shukla, Hugo Fernandez, James Foran, Larry Cripe, Hillard Lazarus, Peter Wiernik, Jacob Rowe, Martin Tallman, Mark Litzow, Yanming Zhang, Selina Luger, Irum Khan
Journal: Blood
Blood (2025) 146 (Supplement 1): 290.
https://doi.org/10.1182/blood-2025-290
Published: 2025
Journal Articles

Sparse whole genome sequencing and machine learning of AML genomes reveals novel, clinically relevant genetics.

Free
Timour Baslan, Pascal Belleau, Astrid Deschênes, Yanming Zhang, Zhuoxin Sun, Francine Garrett-Bakelman, Maria Kleppe, Elisabeth Paietta, Larry Cripe, Hugo Fernandez, Martin Tallman, Jacob Rowe, Hillard Lazarus, Ari Melnick, Mark Litzow, Ross Levine, Nevenka Dimitrova, Selina Luger, Alexander Krasnitz, Scott Lowe
Journal: Blood
Blood (2025) 146 (Supplement 1): 5263.
https://doi.org/10.1182/blood-2025-5263
Published: 2025
Journal Articles

IL18-armored CAR T cells in relapsed/refractory B cell acute lymphoblastic leukemia

Free
Matthew Connor, Wei-Ting Hwang, Saar Gill, Alexander Perl, Ximena Jordan Bruno, Nasheed Hossain, Catherine Lai, Alison Loren, Selina Luger, Andrew Matthews, Shannon McCurdy, Pashna Munshi, Keith Pratz, Amanda Cervini, Jean McConville, Joanne Shea, Charles Tongue, Heather Difilippo, Jacob Kesselman, Amy Marshall, Megan Four, Shannon Christensen, Vanessa Gonzalez, Julie Jadlowsky, Gabriela Plesa, Don Siegel, Rachel Leskowitz, Joseph Fraietta, Bruce Levine, David Porter, Elizabeth Hexner, Carl June, Jakub Svoboda, Noelle Frey
Journal: Blood
Blood (2025) 146 (Supplement 1): 812.
https://doi.org/10.1182/blood-2025-812
Published: 2025
Journal Articles

UBA1a dependency leads to synthetic lethality in vacuoles, E1-ligase, x-linked, auto-inflammatory, somatic (VEXAS) syndrome

Free
Bryan Ciccarelli, Daniel Brown, Nathan Welty, Om Gandhi, Brandon Simone, Selina Luger, Saar Gill
Journal: Blood
Blood (2025) 146 (Supplement 1): 4944.
https://doi.org/10.1182/blood-2025-4944
Published: 2025
Journal Articles

Myeloid malignancies molecular analysis for therapy choice (myeloMATCH): Rapid availability of clinical, pathologic and molecular features for treatment assignment in the first 550 patients.

Free
Eric Winer, Megan Othus, Ehab Atallah, Stephanie Tsai, Mitchell Sabloff, Afaf Osman, Annie Im, Sanam Loghavi, Anna Moseley, Brent Wood, Min Fang, Cecilia Yeung, Xueyan Chen, Xiaoyu QU, Lyndsay Harris, Sayak Ghatak, Steven Gore, Geoffrey Uy, Laura Michaelis, Olatoyosi Odenike, Richard Stone, Selina Luger, Sarit Assouline, Harry Erba, Mark Litzow, Curtis Lachowiez, John Reagan, Uma Borate, Mary Lynn Savoie, Brian Jonas, Ntasha Roy, Jerald Radich, Richard Little, Shahanawaz Jiwani
Journal: Blood
Blood (2025) 146 (Supplement 1): 5279.
https://doi.org/10.1182/blood-2025-5279
Published: 2025
Journal Articles

Fried's frailty phenotype predicts survival in pts with relapsed/refractory lymphoma or myeloma undergoing chimeric antigen receptor T-cell therapy – a prospective, observational Study

Free
Nikita Dave, Shannon Gier, Marni Kessler, Miguel Rodriguez, Stefan Barta, Elise Chong, Adam Cohen, Noelle Frey, Saar Gill, Shannon Heck, Elizabeth Hexner, Nasheed Hossain, Shivani Kapur, Daniel Landsburg, Alison Loren, Selina Luger, Mary Ellen Martin, Pashna Munshi, Sunita Dwivedy Nasta, Alexander Perl, David Porter, Stephen Schuster, Edward Stadtmauer, Sandra Susanibar-Adaniya, Jakub Svoboda, Abby Togliatii, Dan Vogl, Adam Waxman, Daniel Wu, Shannon McCurdy
Journal: Blood
Blood (2025) 146 (Supplement 1): 7189.
https://doi.org/10.1182/blood-2025-7189
Published: 2025
Journal Articles

Toxicities on the E1910 phase III randomized trial of blinatumomab plus chemotherapy in adults with BCR:ABL-1 negative acute lymphoblastic leukemia

Free
Anjali Advani, Li Chen, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Dan Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 5120.
https://doi.org/10.1182/blood-2025-5120
Published: 2025
Journal Articles

Title: Clinical trial availability and receipt of guideline concordant care among adolescents and young adults (AYAs) with acute lymphoblastic leukemia

Free
Julie Wolfson, Michelle Nuno, Abbie Kleckley, Allison Grimes, Michael Roth, Melissa Beauchemin, Subhash Ramakrishnan, David Dickens, Wendy Woods, Kandice Adams, Tawa Alabi, Jennifer Levine, Michele Scialla, Koh Boyaue, Olivia Ponce, Sarah Vargas, George Chang, Wendy Stock, Dawn Hershman, Emily Curran, Anjali Advani, Kristen O'Dwyer, Selina Luger, Jijun Liu, David Robert Freyer, Lillian Sung, Susan Parsons
Journal: Blood
Blood (2025) 146 (Supplement 1): 6190.
https://doi.org/10.1182/blood-2025-6190
Published: 2025
Journal Articles

Social determinants of health and access to allogeneic hematopoietic cell transplantation for acute myeloid leukemia

Free
CME Clinical Trials & Observations
Natalie Wuliji, Salene M. W. Jones, Ted Gooley, Aaron T. Gerds, Bruno C. Medeiros, Paul J. Shami, John Galvin, Kehinde Adekola, Selina Luger, Maria R. Baer, David Rizzieri, Tanya M. Wildes, Eunice S. Wang, Mikkael A. Sekeres, Sudipto Mukherjee, Julie Smith, Mitchell Garrison, Kiarash Kojouri, Jacob Appelbaum, Mary-Elizabeth Percival, Brenda M. Sandmaier, Stephanie Lee, Frederick R. Appelbaum, Rayne Rouce, Mohamed L. Sorror
Journal: Blood
Blood (2025) 145 (25): 3041–3051.
https://doi.org/10.1182/blood.2024027543
Published: 2025
Includes: Supplemental data
Journal Articles

Trial in Progress: The Phase 3, Randomized, Double-Blind, Placebo-Controlled QuANTUM-Wild Study of Quizartinib in Combination With Chemotherapy and as Single-Agent Maintenance in Newly Diagnosed, FLT3 -ITD-Negative Acute Myeloid Leukemia

Free
Pau Montesinos, June-Won Cheong, Naval Daver, Amir T. Fathi, Mark J. Levis, Selina Luger, Toshihiro Miyamoto, Esther Natalie Oliva, Alexander E. Perl, Christian Récher, Richard F. Schlenk, Jianxiang Wang, Amer M. Zeidan, Li Liu, Yvonne Duong, Karima Imadalou, Karenza Alexis, Akash Nahar, Kristy Burns, Harry P. Erba
Journal: Blood
Blood (2024) 144 (Supplement 1): 1504.3.
https://doi.org/10.1182/blood-2024-205101
Published: 2024
Journal Articles

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

Free
Nikolai A. Podoltsev, Zhuoxin Sun, Mark R. Litzow, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard M. Stone, Charles G. Mullighan, Martin S. Tallman, Selina Luger, Ryan J Mattison
Journal: Blood
Blood (2024) 144 (Supplement 1): 4211.
https://doi.org/10.1182/blood-2024-207143
Published: 2024
Journal Articles

A Randomized Phase II Study of Venetoclax and HMA-Based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia (AML): A Myelomatch Treatment Trial: ECOG-ACRIN MM20A-EA02

Free
Jessica Kaplan Altman, Zhuoxin Sun, Alexander E. Perl, Richard Little, Steven D. Gore, Laura C. Michaelis, Geoffrey L. Uy, Yasmin Abaza, Sameem Abedin, John L. Reagan, Ehab L. Atallah, Selina Luger, Mark R. Litzow
Journal: Blood
Blood (2024) 144 (Supplement 1): 2907.1.
https://doi.org/10.1182/blood-2024-199701
Published: 2024
Journal Articles

Gilteritinib Results in Higher Remission and Transplant Rates Than Midostaurin but Does Not Increase the Post-Induction Mutational MRD Negative Rate: Results of the Phase 2 Randomized Precog 0905 Study in Newly Diagnosed FLT3 Mutated AML

Free
Selina Luger, Li Chen, Keith W. Pratz, Sanam Loghavi, Alexander E. Perl, Jessica K. Altman, Robert L. Redner, Amir T. Fathi, Ayman Qasrawi, Adam S. Asch, Deepa Jeyakumar, James M. Foran, Mithun V Shah, Jonathan E Kolitz, Ellin Berman, Lindsay Wilde, Sameem Abedin, Vamsi K. Kota, Krishna Gundabolu, Kristen M. O'Dwyer, Emily K Curran, Ashwin Kishtagari, Kelly Ross, Zhuoxin Sun, Mark R. Litzow
Journal: Blood
Blood (2024) 144 (Supplement 1): 221.
https://doi.org/10.1182/blood-2024-201595
Published: 2024