1-19 of 19
Joseph Fraietta
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

CD19 CAR T cell therapy is an effective strategy for first CNS relapse in pediatric b ALL

Free
Amanda DiNofia, Regina Myers, Yimei Li, Hongyan Liu, Richard Aplenc, Diane Baniewicz, Allison Barz Leahy, Lucy Cain, Colleen Callahan, Caroline Diorio, Joseph Fraietta, Elizabeth Hexner, Caitlin Hopkins, Stephen Hunger, Vanessa Gonzalez, Julie Jadlowsky, Mariam Kerolos, Raabia Khan, Susan McClory, Shannon Maude, Gabriela Plesa, Susan Rheingold, Mackenzie Stewart, Sarah Tasian, Melissa Varghese, Lisa Wray, Stephan Grupp
Journal: Blood
Blood (2025) 146 (Supplement 1): 648.
https://doi.org/10.1182/blood-2025-648
Published: 2025
Journal Articles

Humanized CD19 chimeric antigen receptor (CAR) T-cell therapy for high-risk and post-CAR relapse of B-cell acute lymphoblastic leukemia

Free
Lucy Cain, Yimei Li, Hongyan Liu, Shannon Christensen, Regina Myers, Allison Barz Leahy, Caroline Diorio, Nancy Shapiro, Elizabeth McBride, Colleen Callahan, Diane Baniewicz, Amanda DiNofia, Susan Rheingold, Lisa Wray, Stephen Hunger, Richard Aplenc, Susan McClory, Mackenzie Stewart, Gerald Wertheim, Andrew Fesnak, Gabriela Plesa, Don Siegel, Joseph Fraietta, Vanessa Gonzalez, Caitlin Hopkins, Amy Marshall, Amanda Kotch, Bruce Levine, Anne Chew, Elizabeth Hexner, Carl June, Stephan Grupp, Shannon Maude
Journal: Blood
Blood (2025) 146 (Supplement 1): 646.
https://doi.org/10.1182/blood-2025-646
Published: 2025
Journal Articles

Naive CD4+ at apheresis and disease control at infusion are associated with improved efficacy in second-line CAR T-cells

Free
Federico Stella, Michael Schneider, Luca Paruzzo, Julia Han Noll, Pooja Devi, Victor Babatunde, Elise Chong, Matthew Ho, Colin Thomas, Michael Cook, Nasheed Hossain, Jordan Carter, Ziyu Li, Melody Tan, Peter Michener, Puneeth Guruprasad, Vrutti Patel, Antonio Imparato, Alberto Carturan, Jean Lemoine, Vitor Souza, Patrizia Porazzi, Joseph Fraietta, Stefan Barta, Sunita Dwivedy Nasta, Jakub Svoboda, Stephen J. Schuster, Ivan Maillard, Daniel Landsburg, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2755.
https://doi.org/10.1182/blood-2025-2755
Published: 2025
Journal Articles

Epigenetic reprogramming via EZH1/2 inhibition enhances T cell-mediated immunotherapies against multiple myeloma

Free
Patrizia Porazzi, Martina Pucillo, Anushka Anant Padmanabhan, Siena Nason, Zhixuan Zheng, Luca Paruzzo, Matthew Ho, Peter Michener, Federico Stella, Antonio Imparato, Sandra Susanibar-Adaniya, Alfred Garfall, Joseph Fraietta, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 2160.
https://doi.org/10.1182/blood-2025-2160
Published: 2025
Journal Articles

CCR5 blockade: A therapeutic approach to uncouple CART-BCMA expansion from CART-mediated immune toxicities.

Free
Luca Paruzzo, Matthew Ho, Julia Han Noll, Federico Stella, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Andrew Huff, Danuta Jarocha, Owen Koucky, Caitlin Hopkins, Alex Dimitri, Maya Lavorando, Dan Vogl, John Scholler, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Patrizia Porazzi, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Adam Cohen, Joseph Fraietta, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 5945.
https://doi.org/10.1182/blood-2025-5945
Published: 2025
Journal Articles

Type II interferon-driven crosstalk between effector memory CART and myeloid cells is associated with CART19 resistance in relapsed refractory large B-cell lymphomas

Free
Alice Wang, Luca Paruzzo, Martina Bonomi, Chia-Hui Chen, Ivan Cohen, John DiMaio, Kyung Jin Ahn, Peter Michener, Jaryse Harris, Arati Inamdar, Pooja Devi, Emeline Chong, Siddharth Bhattacharyya, Vrutti Patel, Patrizia Porazzi, Joseph Fraietta, Stephen Schuster, Fabio Luciani, Marco Ruella, Kai Tan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5337.
https://doi.org/10.1182/blood-2025-5337
Published: 2025
Journal Articles

IL18-armored CAR T cells in patients with CLL/SLL and Richter's transformation after prior BTK inhibitor and venetoclax failure

Free
Jakub Svoboda, Stephen Schuster, David Porter, Michael Cook, Sunita Dwivedy Nasta, Daniel Landsburg, Stefan Barta, Marco Ruella, Elise Chong, Jordan Carter, Colin Thomas, Emily Tomasulo, Noelle Frey, Matthew Connor, Joanne Shea, Amanda Cervini, Jean McConville, Charles Tongue, Megan Four, Amy Marshall, Wei-Ting Hwang, Rachel Leskowitz, Vanessa Gonzalez, Shannon Christensen, Gabriela Plesa, Don Siegel, Julie Jadlowsky, Joseph Fraietta, Bruce Levine, Elizabeth Hexner, Carl June
Journal: Blood
Blood (2025) 146 (Supplement 1): 2394.
https://doi.org/10.1182/blood-2025-2394
Published: 2025
Journal Articles

Patient-informed CRISPR screening reveals gene targets to improve CAR T-cell efficacy

Free
Beatriz Coutinho De Oliveira, Meraj Khan, Cassandra Gilmour, Saaurav Bari, Jessica Kerr, Yee Peng Phoon, Joseph Fraietta, Frederic Bushman, J. Joseph Melenhorst
Journal: Blood
Blood (2025) 146 (Supplement 1): 106.
https://doi.org/10.1182/blood-2025-106
Published: 2025
Journal Articles

Early administration of CD20 x CD3 bispecific antibodies 4-6 weeks after CAR-T infusion for patients with residual or progressive large B cell lymphomas

Free
Elise Chong, Rachel Lundberg, Matthew Lunning, Stefan Barta, Jordan Carter, Michael Cook, Joseph Fraietta, Daniel Landsburg, Hwan Lee, Sunita Dwivedy Nasta, Jakub Svoboda, Colin Thomas, Christopher D'Angelo, Robert Bociek, Megan Jones, Kaitlin Kennard, Brittany Koch, Peter Michener, Allison Nelson, Alvaro Ordonez, Luca Paruzzo, Marco Ruella, Mark Sellmyer, Ellen Napier, Emeline Chong, Stephen Schuster
Journal: Blood
Blood (2025) 146 (Supplement 1): 1952.
https://doi.org/10.1182/blood-2025-1952
Published: 2025
Journal Articles

IL18-armored CAR T cells in relapsed/refractory B cell acute lymphoblastic leukemia

Free
Matthew Connor, Wei-Ting Hwang, Saar Gill, Alexander Perl, Ximena Jordan Bruno, Nasheed Hossain, Catherine Lai, Alison Loren, Selina Luger, Andrew Matthews, Shannon McCurdy, Pashna Munshi, Keith Pratz, Amanda Cervini, Jean McConville, Joanne Shea, Charles Tongue, Heather Difilippo, Jacob Kesselman, Amy Marshall, Megan Four, Shannon Christensen, Vanessa Gonzalez, Julie Jadlowsky, Gabriela Plesa, Don Siegel, Rachel Leskowitz, Joseph Fraietta, Bruce Levine, David Porter, Elizabeth Hexner, Carl June, Jakub Svoboda, Noelle Frey
Journal: Blood
Blood (2025) 146 (Supplement 1): 812.
https://doi.org/10.1182/blood-2025-812
Published: 2025
Journal Articles

Delayed neurotoxicity, enterocolitis, and BCMA-CART-associated immune-related adverse events (CirAE)  are caused by CD4+ CAR T-cells

Free
Julia Han Noll, Matthew Ho, Luca Paruzzo, Federico Stella, Pooja Devi, Sonia Ndeupen, Gregory Chen, Ivan Cohen, Angel Ramirez-Fernandez, Adam Waxman, Shivani Kapur, Fang Chen, Rong Xu, Andrew Huff, Danuta Jarocha, Vrutti Patel, Audrey Bochi-Layec, Ranjani Ramasubramanian, Shan Liu, Riemke Bouvier, Vitor Souza, Heta Patel, Ziyu Li, Alberto Carturan, Peter Michener, Caitlin Hopkins, Owen Koucky, Janna Minehart, Alex Dimitri, Neel Nabar, Zainul Hasanali, Bryan Ciccarelli, Erik Williams, Robert Bartoszek, Maya Lavorando, Suyash Mohan, Vanessa Gonzalez, Patrizia Porazzi, Vijay Bhoj, Sokratis Apostolidis, Dan Vogl, David Porter, John Scholler, Caroline Diorio, Aoife Doto, John Everett, Frederic Bushman, Katherine Nathanson, Edward Stadtmauer, Sandra Susanibar-Adaniya, Alfred Garfall, Marco Ruella, Adam Cohen, Joseph Fraietta
Journal: Blood
Blood (2025) 146 (Supplement 1): 804.
https://doi.org/10.1182/blood-2025-804
Published: 2025
Journal Articles

Phase 2 study of cevostamab consolidation following BCMA CAR T cell therapy:  preliminary safety, efficacy, and correlative data from the “STEM” (Sequential T Cell-Engagement for Myeloma) trial

Free
Adam Cohen, Sandra Susanibar-Adaniya, Alfred Garfall, Dan Vogl, Shivani Kapur, Adam Waxman, Danielle Zubka, Wei-Ting Hwang, Cynthia Diaczynsky, Julia Han Noll, Matthew Ho, Luca Paruzzo, Bing Yi, Rong Xu, Elina Thai, Vanessa Gonzalez, Peter Michener, Marco Ruella, Joseph Fraietta, Edward Stadtmauer
Journal: Blood
Blood (2025) 146 (Supplement 1): 699.
https://doi.org/10.1182/blood-2025-699
Published: 2025
Journal Articles

Title first‑in‑human Phase 1 dose‑finding study (VIPER 101) of dual‑population autologous CD5‑deleted anti-CD5 CAR‑T (Senza5 CART5) cells in Relapsed/Refractory T‑cell lymphomas

Free
Stefan Barta, Stephen Schuster, Jakub Svoboda, Jordan Carter, Elise Chong, Daniel Landsburg, Sunita Dwivedy Nasta, Ruchi Patel, Joseph Fraietta, Colin Thomas, Omar Elghawy, Ran Reshef, Aditya Nimmagadda, Lavanya Peddada, Adam Snook, Nicholas Siciliano, Rosemary Mazanet, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4174.
https://doi.org/10.1182/blood-2025-4174
Published: 2025
Journal Articles

Chimeric antigen receptor T-cell therapy in patients with coexisting malignancy and autoimmune disease

Free
Luca Paruzzo, Riemke Bouvier, Bria Fulmer, Ivan Cohen, Elise Chong, Jakub Svoboda, Sunita Dwivedy Nasta, Daniel Landsburg, Vrutti Patel, Matthew Ho, Alberto Carturan, Federico Stella, Adam Waxman, Adam Cohen, Dan Vogl, Stefan Barta, Audrey Bochi-Layec, Patrizia Porazzi, Joseph Fraietta, Alfred Garfall, Vijay Bhoj, Edward Stadtmauer, David Porter, James Riley, Peter Merkel, Stephen Schuster, Jordan Carter, Sokratis Apostolidis, Sandra Susanibar-Adaniya, Marco Ruella
Journal: Blood
Blood (2025) 146 (Supplement 1): 4543.
https://doi.org/10.1182/blood-2025-4543
Published: 2025
Journal Articles

CD123-directed chimeric antigen receptor T-cell (CART123) therapy for relapsed/refractory pediatric acute myeloid leukemia

Free
Lucy Cain, Yimei Li, Anand Bhagwat, Diane Baniewicz, Allison Barz Leahy, Colleen Callahan, Shannon Christensen, Angela Cosey, Amanda DiNofia, Caroline Diorio, Joseph Fraietta, Vanessa Gonzalez, Elizabeth Hexner, Stephen Hunger, Amy Marshall, Shannon Maude, Susan McClory, Regina Myers, Gabriela Plesa, Susan Rheingold, Aakruti Sharma, Mackenzie Stewart, Lisa Wray, Earline Young-Robinson, Stephan Grupp, Saar Gill, Sarah Tasian, Richard Aplenc
Journal: Blood
Blood (2025) 146 (Supplement 1): 1643.
https://doi.org/10.1182/blood-2025-1643
Published: 2025
Journal Articles

Interleukin-18 Secreting Autologous Anti-CD19 CAR T-Cells (huCART19-IL18) in Patients with Non-Hodgkin Lymphomas Relapsed or Refractory to Prior CAR T-Cell Therapy

Free
Jakub Svoboda, James N. Gerson, Daniel J. Landsburg, Elise A. Chong, Stefan K. Barta, Sunita Dwivedy Nasta, Marco Ruella, Elizabeth O. Hexner, Amy Marshall, Rachel Leskowitz, Megan Four, Joanne Shea, Tina Matlawski, Amanda Cervini, Megan M. Davis, Mercy Gohil, John Scholler, Donald Hasenmayer, Juliana Rojas Amortegui, Andrea Brennan, Gabriela Plesa, Wei-Ting Hwang, David L. Porter, Joseph Fraietta, Stephen J. Schuster, Carl H. June
Journal: Blood
Blood (2022) 140 (Supplement 1): 4612–4614.
https://doi.org/10.1182/blood-2022-162393
Published: 2022
Journal Articles

CART22-65s Co-Administered with huCART19 in Adult Patients with Relapsed or Refractory ALL

Free
Noelle V Frey, Saar Gill, Wei-Ting Hwang, Selina M. Luger, Mary Ellen Martin, Shannon R. McCurdy, Alison W. Loren, Keith W. Pratz, Alexander E. Perl, Julie Barber-Rotenberg, Amy Marshall, Marco Ruella, Simon F Lacey, Joseph Fraietta, Andrew Fesnak, Megan O'brien, Theresa Schanne, Jennifer L Brogdon, Boris Engels, Bruce L Levine, Carl H June, David L Porter, Elizabeth O. Hexner
Journal: Blood
Blood (2021) 138 (Supplement 1): 469.
https://doi.org/10.1182/blood-2021-153955
Published: 2021
Journal Articles

Signaling Domain of Chimeric Antigen Receptors Can Reprogram T Cells

Free
Omkar Uday Kawalekar, MS, BS, Roddy O'Connor, PhD, Sonia Guedan, PhD, Joseph Fraietta, PhD, Avery D. Posey, PhD, John Scholler, Michael C Milone, MD PhD, Carl H. June, MD
Journal: Blood
Blood (2014) 124 (21): 551.
https://doi.org/10.1182/blood.V124.21.551.551
Published: 2014
Journal Articles

Distinct Signaling By Chimeric Antigen Receptors (CARs) Containing CD28 Signaling Domain Versus 4-1BB In Primary Human T Cells

Free
Omkar Uday Kawalekar, MS, BS, Avery D. Posey, Jr., Joseph Fraietta, Jihyun Lee, John Scholler, Yangbing Zhao, Carl H. June, MD
Journal: Blood
Blood (2013) 122 (21): 2902.
https://doi.org/10.1182/blood.V122.21.2902.2902
Published: 2013