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Journal Articles

CD123-directed chimeric antigen receptor T-cell (CART123) therapy for relapsed/refractory pediatric acute myeloid leukemia

Free
Lucy Cain, Yimei Li, Anand Bhagwat, Diane Baniewicz, Allison Barz Leahy, Colleen Callahan, Shannon Christensen, Angela Cosey, Amanda DiNofia, Caroline Diorio, Joseph Fraietta, Vanessa Gonzalez, Elizabeth Hexner, Stephen Hunger, Amy Marshall, Shannon Maude, Susan McClory, Regina Myers, Gabriela Plesa, Susan Rheingold, Aakruti Sharma, Mackenzie Stewart, Lisa Wray, Earline Young-Robinson, Stephan Grupp, Saar Gill, Sarah Tasian, Richard Aplenc
Journal: Blood
Blood (2025) 146 (Supplement 1): 1643.
https://doi.org/10.1182/blood-2025-1643
Published: 2025
Journal Articles

Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children's Oncology Group studies AALL0932 and AALL1131

Free
Ruth Wang'ondu, Anne Angiolillo, Meenakshi Devidas, Karen Rabin, Michael Borowitz, Brent Wood, Andrew Carroll, Nyla Heerema, Emily Hibbitts, Reuven Schore, William Carroll, Michael Burke, Wanda Salzer, Lia Gore, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Stephen Hunger, John Kairalla
Journal: Blood
Blood (2025) 146 (Supplement 1): 757.
https://doi.org/10.1182/blood-2025-757
Published: 2025
Journal Articles

Factors associated with central nervous system relapse after b-acute lymphoblastic leukemia: A Children's oncology group report

Free
Aman Wadhwa, Lingyun Ji, Alice Dang, Xinxin Xu, Meenakshi Devidas, John Kairalla, Mary Shago, Nyla Heerema, Andrew Carroll, Michael Borowitz, Brent Wood, Eric Larsen, Kelly Maloney, Reuven Schore, Wanda Salzer, Michael Burke, Stephen Hunger, David Teachey, Naomi Winick, Elizabeth Raetz, Mignon Loh, Deepa Bhojwani, Sumit Gupta
Journal: Blood
Blood (2025) 146 (Supplement 1): 762.
https://doi.org/10.1182/blood-2025-762
Published: 2025
Journal Articles

Clinical characteristics and outcomes of children with T-cell acute lymphoblastic leukemia harboring ABL-class fusions: A report from the ponte di legno consortium

Free
Thai Hoa Tran, Meenakshi Devidas, Leyna Xoi, Andishe Attarbaschi, Judith Boer, Gunnar Cario, Giovanni Cazzaniga, Gabriele Escherich, Yoshihiro Gocho, Mats Heyman, Stephen Hunger, Hiroto Inaba, Gabor Kovacs, Anthony Moorman, Charles Mullighan, Kjeld Schmiegelow, Jan Stary, Tomasz Szczepanski, David Teachey, Andrea Biondi, Mignon Loh, Rob Pieters, Sarah Elitzur
Journal: Blood
Blood (2025) 146 (Supplement 1): 761.
https://doi.org/10.1182/blood-2025-761
Published: 2025
Journal Articles

Blinatumomab mitigates the impact of traditional adverse prognosticators among children with standard risk b-acute lymphoblastic leukemia: Updated results of the Children's oncology group (COG) Trial AALL1731

Free
Sumit Gupta, Rachel Rau, John Kairalla, Karen Rabin, Cindy Wang, Anne Angiolillo, Sarah Alexander, Andrew Carroll, Susan Conway, Lia Gore, Ilan Kirsch, Holly Kubaney, Amanda Li, Jennifer McNeer, Olga Militano, Tamara Miller, Yvonne Moyer, Maureen O'Brien, Maki Okada, Shalini Reshmi, Mary Shago, Elizabeth Wagner, Naomi Winick, Brent Wood, Tara Haworth-Wright, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Meenakshi Devidas, Stephen Hunger, David Teachey, Mignon Loh, Elizabeth Raetz
Journal: Blood
Blood (2025) 146 (Supplement 1): 758.
https://doi.org/10.1182/blood-2025-758
Published: 2025
Journal Articles

Outcomes after relapse for adolescent and young adult patients with ALL: Results from the Children's oncology group

Free
Jordyn Griffin, Lingyun Ji, Alice Dang, Xinxin Xu, Loretta Li, Naomi Winick, William Carroll, Stephen Hunger, Elizabeth Raetz, Mignon Loh, Michael Borowitz, Brent Wood, Mary Shago, Nyla Heerema, Andrew Carroll, Jennifer McNeer, Deepa Bhojwani, Susan Rheingold
Journal: Blood
Blood (2025) 146 (Supplement 1): 548.
https://doi.org/10.1182/blood-2025-548
Published: 2025
Journal Articles

Outcomes in children and adolescents with down syndrome and B-lymphoblastic leukemia: A report from Children's oncology group study AALL1731

Free
Amanda Li, John Kairalla, Cindy Wang, Meenakshi Devidas, Olga Militano, Johann Hitzler, Anne Angiolillo, Michael Burke, Wanda Salzer, Stephen Hunger, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Sumit Gupta, Rachel Rau, Karen Rabin
Journal: Blood
Blood (2025) 146 (Supplement 1): 547.
https://doi.org/10.1182/blood-2025-547
Published: 2025
Journal Articles

CD19 CAR T cell therapy is an effective strategy for first CNS relapse in pediatric b ALL

Free
Amanda DiNofia, Regina Myers, Yimei Li, Hongyan Liu, Richard Aplenc, Diane Baniewicz, Allison Barz Leahy, Lucy Cain, Colleen Callahan, Caroline Diorio, Joseph Fraietta, Elizabeth Hexner, Caitlin Hopkins, Stephen Hunger, Vanessa Gonzalez, Julie Jadlowsky, Mariam Kerolos, Raabia Khan, Susan McClory, Shannon Maude, Gabriela Plesa, Susan Rheingold, Mackenzie Stewart, Sarah Tasian, Melissa Varghese, Lisa Wray, Stephan Grupp
Journal: Blood
Blood (2025) 146 (Supplement 1): 648.
https://doi.org/10.1182/blood-2025-648
Published: 2025
Journal Articles

Humanized CD19 chimeric antigen receptor (CAR) T-cell therapy for high-risk and post-CAR relapse of B-cell acute lymphoblastic leukemia

Free
Lucy Cain, Yimei Li, Hongyan Liu, Shannon Christensen, Regina Myers, Allison Barz Leahy, Caroline Diorio, Nancy Shapiro, Elizabeth McBride, Colleen Callahan, Diane Baniewicz, Amanda DiNofia, Susan Rheingold, Lisa Wray, Stephen Hunger, Richard Aplenc, Susan McClory, Mackenzie Stewart, Gerald Wertheim, Andrew Fesnak, Gabriela Plesa, Don Siegel, Joseph Fraietta, Vanessa Gonzalez, Caitlin Hopkins, Amy Marshall, Amanda Kotch, Bruce Levine, Anne Chew, Elizabeth Hexner, Carl June, Stephan Grupp, Shannon Maude
Journal: Blood
Blood (2025) 146 (Supplement 1): 646.
https://doi.org/10.1182/blood-2025-646
Published: 2025
Journal Articles

Inadequate social support and household material hardship among children with pediatric acute lymphoblastic leukemia: A report from the Children's oncology group Trial AALL1731

Free
Selena Murcia Mendez, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Rahela Aziz-Bose, Colleen Kelly, Haley Newman, Daniel Zheng, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona, Puja Umaretiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 132.
https://doi.org/10.1182/blood-2025-132
Published: 2025
Journal Articles

Feasibility of collecting social determinants of health data in the frontline pediatric acute lymphoblastic leukemia (ALL) trial AALL1731: A report from the Children's oncology group

Free
Haley Newman, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Colleen Kelly, Daniel Zheng, Rahela Aziz-Bose, Puja Umaretiya, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona
Journal: Blood
Blood (2025) 146 (Supplement 1): 2742.
https://doi.org/10.1182/blood-2025-2742
Published: 2025
Journal Articles

Improved Diagnosis of Intrachromosomal Amplification of Chromosome 21 (iAMP21) By Copy Number Profiling

Free
Claire Schwab, Paul Sinclair, PhD, Anthony V. Moorman, PhD, Stephen Hunger, MD, Mignon L. Loh, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Christine Harrison
Journal: Blood
Blood (2016) 128 (22): 1733.
https://doi.org/10.1182/blood.V128.22.1733.1733
Published: 2016
Journal Articles

Outcomes of Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Based on Blast Genotype at Diagnosis: A Report from the Children's Oncology Group

Free
Mignon L. Loh, MD, Elizabeth Raetz, MD, Meenakshi Devidas, PhD, Yunfeng Dai, PhD, Michael J. Borowitz, MD PhD, Andrew J. Carroll, PhD, I-Ming Chen, DVM, MS, Julie M. Gastier-Foster, PhD, Alison M. Friedmann, MD MSC, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Eric Larsen, MD, Yongjin Li, PhD, Kelly W. Maloney, MD, Leonard A. Mattano, Jr., MD, Charles G. Mullighan, MBBS, MSc, PhD, Karen R. Rabin, MD PhD, Shalini C. Reshmi, PhD, Kathryn G. Roberts, PhD, Cheryl L. Willman, MD, Brent L. Wood, MD PhD, Patrick Zweidler-McKay, MD PhD, Jinghui Zhang, PhD, Naomi Winick, MD, Stephen Hunger, MD, William L. Carroll, MD
Journal: Blood
Blood (2016) 128 (22): 451.
https://doi.org/10.1182/blood.V128.22.451.451
Published: 2016
Journal Articles

Minimal Residual Disease Assessment of Remission after Induction Therapy Is Superior to Morphologic Assessment for Risk Stratification in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group (COG)

Free
Sumit Gupta, MD, Meenakshi Devidas, PhD, Si Chen, MS, Cindy Wang, MSc, Mignon L. Loh, MD, Elizabeth Raetz, MD, Patrick Brown, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Julie M. Gastier-Foster, PhD, Kimberly P. Dunsmore, MD, Eric Larsen, MD, Kelly Maloney, MD, Leonard A. Mattano, Jr., MD, Stuart Winter, MD, Naomi Winick, MD, William L. Carroll, MD, Stephen Hunger, Michael J. Borowitz, MD PhD, Brent L. Wood, MD PhD
Journal: Blood
Blood (2016) 128 (22): 758.
https://doi.org/10.1182/blood.V128.22.758.758
Published: 2016
Journal Articles

Evaluation of Minimal Residual Disease As a Surrogate Endpoint for Event Free Survival in Childhood B-Lineage Acute Lymphoblastic Leukemia

Free
Maria Grazia Valsecchi, PhD, Meenakshi Devidas, PhD, Ausiliatrice Lucenti, PhD, Martin Schrappe, MD, Giovanni Cazzaniga, PhD, Anja Moricke, MD, Claus R. Bartram, PhD, Georg Mann, MD, William L. Carroll, MD, Eric Larsen, MD, Naomi Winick, MD, Giuseppe Basso, MD, Valentino Conter, Martin Zimmermann, PhD, Stefan Sushu, Andrea Biondi, MD, Stephen Hunger, MD, Stefania Galimberti, PhD
Journal: Blood
Blood (2016) 128 (22): 759.
https://doi.org/10.1182/blood.V128.22.759.759
Published: 2016
Journal Articles

PRC2 Mutations Induce Resistance to Conventional Chemotherapy By Inhibiting Mitochondrial Apoptosis in T-Cell Acute Lymphoblastic Leukemia

Free
Ingrid Ariës, PhD, Triona Ni Chonghaile, PhD, Salmaan Karim, Mina Jacob, Kristen E. Stevenson, MS, Donna S. Neuberg, ScD, Meenakshi Devidas, PhD, Mignon Loh, MD, Stephen Hunger, David T Teachey, MD, Karen R. Rabin, MD PhD, Stuart S. Winter, MD, Kimberly P. Dunsmore, MD, Brent L. Wood, MD PhD, Lewis B. Silverman, MD, Stephen E. Sallan, MD, Birgit Knoechel, MD PhD, Pieter Van Vlierberghe, PhD, Anthony Letai, MD PhD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2016) 128 (22): 604.
https://doi.org/10.1182/blood.V128.22.604.604
Published: 2016
Journal Articles

Cryptic Truncating Rearrangements of the Erythropoietin Receptor in Ph-like Acute Lymphoblastic Leukemia

Free
Ilaria Iacobucci, PhD, Kathryn G. Roberts, PhD, Yongjin Li, PhD, Debbie Payne-Turner, BS, Marcus Valentine, BA, Jinghui Zhang, PhD, Richard C. Harvey, PhD, Kelly McCastlain, BS, John Easton, PhD, I-Ming L. Chen, DVM, Michael Rusch, BA, Steven M. Kornblau, MD, Marina Konopleva, MD PhD, Elisabeth M. Paietta, PhD, Jacob M. Rowe, MD, Ching-Hon Pui, MD, Julie Gastier-Foster, PhD, Mignon Loh, MD, Cheryl L. Willman, MD, James R Downing, MD, Stephen Hunger, MD, Charles G. Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2014) 124 (21): 128.
https://doi.org/10.1182/blood.V124.21.128.128
Published: 2014
Journal Articles

Outstanding Outcome for Children with Standard Risk-Low (SR-Low) Acute Lymphoblastic Leukemia (ALL) and No Benefit to Intensified Peg-Asparaginase (PEG-ASNase) Therapy: Results of Children’s Oncology Group (COG) Study AALL0331

Free
Leonard A. Mattano, MD, Meenakshi Devidas, PhD, Alison M. Friedmann, MD MSC, Elizabeth A. Raetz, MD, Mignon Loh, MD, Patrick Buckley, MD PhD, Michael J. Borowitz, MD PhD, Andrew J. Carroll, PhD, Julie Gastier-Foster, PhD, Nyla A. Heerema, PhD, Nina Kadan-Lottick, MD MSPH, Yousif Matloub, MD, David T Marshall, MD, Linda C. Stork, MD, Brent L. Wood, MD PhD, Naomi J. Winick, MD, Stephen Hunger, MD, William L. Carroll, MD, Kelly Maloney, MD
Journal: Blood
Blood (2014) 124 (21): 793.
https://doi.org/10.1182/blood.V124.21.793.793
Published: 2014
Journal Articles

Genetic Variation in NFATC2 Is Associated with a Higher Risk of Asparaginase Allergy

Free
Christian A. Fernandez, PhD, Colton Smith, PhD, Wenjian Yang, PhD, Charles G. Mullighan, MBBS, MSc, MD, Chunxu Qu, PhD, Eric C. Larsen, MD, William Paul Bowman, MD, Chengcheng Liu, Laura B. Ramsey, PhD, Tamara Chang, MD, Seth E. Karol, MD, Mignon L. Loh, MD, Elizabeth A. Raetz, MD, Naomi J. Winick, MD, Stephen Hunger, MD, William L. Carroll, MD, Sima Jeha, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Meenakshi Devidas, PhD, Mary V. Relling, PharmD
Journal: Blood
Blood (2014) 124 (21): 63.
https://doi.org/10.1182/blood.V124.21.63.63
Published: 2014
Journal Articles

Outcomes after Intermediate-Risk Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) and the Role of Allogeneic Stem Cell Transplantation (SCT): A Report from Children's Oncology Group (COG) AALL0433

Free
Glen Lew, MD, Xiaomin Lu, PhD, Rochelle Yanofsky, MD FRCP(C), Susan R. Rheingold, MD, James Whitlock, Qi An, Meenakshi Devidas, PhD, Caroline A. Hastings, MD, Naomi J. Winick, MD, William L. Carroll, MD, Michael J. Borowitz, MD PhD, Stephen Hunger, MD, Michael A. Pulsipher, MD
Journal: Blood
Blood (2014) 124 (21): 684.
https://doi.org/10.1182/blood.V124.21.684.684
Published: 2014