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Journal Articles

Tallforest: Multi-omic classifier for T-lineage acute lymphoblastic leukemia

Free
Petri Polonen, Yiping Fan, Shaohua Lei, Qingsong Gao, Yiming Wu, Ti-Cheng Chang, Haley Newman, Lahari Uppuluri, Niroshan Nadarajah, Torsten Haferlach, Marketa Zaliova, Jan Trka, Lu Wang, Hiroto Inaba, Stanley Pounds, Gang Wu, David Teachey, Charles Mullighan
Journal: Blood
Blood (2025) 146 (Supplement 1): 336.
https://doi.org/10.1182/blood-2025-336
Published: 2025
Journal Articles

Cumulative incidence of household material hardship and income loss as measures of financial toxicity during pediatric acute lymphoblastic leukemia (ALL) treatment: A report from the DFCI ALL 16-001 Trial

Free
Daniel Zheng, Eva Robinson, Yael Flamand, Rahela Aziz-Bose, Victoria Koch, Peter Cole, Lisa Gennarini, Kelly Getz, Justine Kahn, Kristine Karvonen, Colleen Kelly, Kara Kelly, Bruno Michon, Haley Newman, Morgan Paul, Thai Tran, Puja Umaretiya, Jennifer Welch, Edie Weller, Lewis Silverman, Kira Bona
Journal: Blood
Blood (2025) 146 (Supplement 1): 710.
https://doi.org/10.1182/blood-2025-710
Published: 2025
Journal Articles

Inadequate social support and household material hardship among children with pediatric acute lymphoblastic leukemia: A report from the Children's oncology group Trial AALL1731

Free
Selena Murcia Mendez, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Rahela Aziz-Bose, Colleen Kelly, Haley Newman, Daniel Zheng, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona, Puja Umaretiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 132.
https://doi.org/10.1182/blood-2025-132
Published: 2025
Journal Articles

National landscape of real-world pediatric blinatumomab care delivery in the United States: A report from the Children's Oncology Group

Free
Daniel Zheng, Katelyn Oranges, Subhash Ramakrishnan, Sarah Alexander, Allison Barz Leahy, Melissa Beauchemin, Kira Bona, Sharon Castellino, Sumit Gupta, Doug Hawkins, Lingyun Ji, Olga Militano, Kathleen Montgomery, Haley Newman, Rachel Rau, Susan Rheingold, Joanna Robles, Michael Roth, David Teachey, Sue Zupanec, Susan Parsons
Journal: Blood
Blood (2025) 146 (Supplement 1): 1077.
https://doi.org/10.1182/blood-2025-1077
Published: 2025
Journal Articles

Feasibility of collecting social determinants of health data in the frontline pediatric acute lymphoblastic leukemia (ALL) trial AALL1731: A report from the Children's oncology group

Free
Haley Newman, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Colleen Kelly, Daniel Zheng, Rahela Aziz-Bose, Puja Umaretiya, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona
Journal: Blood
Blood (2025) 146 (Supplement 1): 2742.
https://doi.org/10.1182/blood-2025-2742
Published: 2025
Journal Articles

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Open Access
Changya Chen, Jason Xu, Jonathan H. Sussman, Tiffaney Vincent, Joseph S. Tumulty, Satoshi Yoshimura, Fatemeh Alikarami, Wenbao Yu, Yang-yang Ding, Chia-hui Chen, Elizabeth Y. Li, Austin Yang, Xiaohuan Qin, Shovik Bandyopadhyay, Jacqueline Peng, Petri Pölönen, Haley Newman, Brent L. Wood, Jianzhong Hu, Rawan Shraim, Andrew D. Hughes, Caroline Diorio, Lahari Uppuluri, Gongping Shi, Theresa Ryan, Tori Fuller, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Stanley B. Pounds, Charles G. Mullighan, David Frank, Jun J. Yang, Kathrin M. Bernt, David T. Teachey, Kai Tan
Journal: Blood
Blood (2025) 145 (23): 2685–2700.
https://doi.org/10.1182/blood.2024027270
Published: 2025
Includes: Supplemental data
Journal Articles

STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

Available to Purchase
Clinical Trials & Observations
Jason Xu, Jonathan H. Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney Vincent, Shovik Bandyopadhyay, Elizabeth Y. Li, Tristan Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L. Wald, Gregory M. Chen, David Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Bernt, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Elizabeth Raetz, Meenakshi Devidas, Stanley Pounds, Mignon Loh, Stephen P. Hunger, Mark Y. Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2025) 145 (23): 2793–2798.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Free
Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

Serum-Based Proteomic Analysis of Cytokine Release Syndrome in Pediatric AML Patients Receiving CART123

Free
Saamia Farooki, Han R Fisher, Anand S Bhagwat, Tina Glisovic-Aplenc, Lusha Cao, Regina M. Myers, Haley Newman, Caroline Diorio, Saar Gill, Richard Aplenc
Journal: Blood
Blood (2024) 144 (Supplement 1): 2946.
https://doi.org/10.1182/blood-2024-201034
Published: 2024
Journal Articles

Preinfusion Risk Factors for the Development of Severe Immune Effector Cell Associated Neurotoxicity Syndrome Following Chimeric Antigen Receptor T-Cell Infusion in Pediatric Patients

Free
Caroline Diorio, Regina M. Myers, Yimei Li, Amanda M. Dinofia, Hongyan Liu, Allison Barz Leahy, Haley Newman, Jillian Dolan, Zachary Martinez, Amira Elhachimi, Cassidy Mullen, Alexander Lai Li, John Kim, David T. Teachey, Shannon L. Maude, Jennifer McGuire, Stephan A. Grupp
Journal: Blood
Blood (2024) 144 (Supplement 1): 3454.
https://doi.org/10.1182/blood-2024-204993
Published: 2024
Journal Articles

Real-World Generalizability of Clinical Trial Cytomolecular Features By Race and Ethnicity in Pediatric Acute Myeloid Leukemia (AML)

Free
Daniel J. Zheng, Gary Hettinger, Catherine Aftandilian, Kira Bona, Emi H. Caywood, Anderson B. Collier, Caitlin W. Elgarten, Cody Gathers, Taumoha Ghosh, Maria Monica Monica Gramatges, Meret Henry, Yuan-Shung V. Huang, Yimei Li, Craig Lotterman, Kelly Maloney, Amir Mian, Tamara P. Miller, Arunkumar Modi, Rajen Mody, Elaine Morgan, Regina M. Myers, Haley Newman, Alix E. Seif, Caroline Smith, Jamie Stokke, Naomi J. Winick, Jennifer J. Wilkes, Victor Wong, Richard Aplenc, Kelly D. Getz
Journal: Blood
Blood (2024) 144 (Supplement 1): 531.
https://doi.org/10.1182/blood-2024-198385
Published: 2024
Journal Articles

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Free
Haley Newman, Lahari Uppuluri, Rawan Shraim, Carl E Allen, Kara L. Davis, Meenakshi Devidas, Caroline Diorio, Kimberly P. Dunsmore, Amira Elhachimi, David Frank, Lia Gore, Thomas Gross, Robert J. Hayashi, Terzah M. Horton, Andrew Hughes, Stephen P. Hunger, John Kim, Yimei Li, Stephanie Si Lim, Mignon L. Loh, Charles G. Mullighan, Adam B. Olshen, Petri Pölönen, Rachel E. Rau, Gongping Shi, Kai Tan, Tiffaney Vincent, Stuart S. Winter, Birte Wistinghausen, Brent L. Wood, Jason Xu, Jun J. Yang, Rodney R. Miles, Michelle L. Hermiston, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 313.
https://doi.org/10.1182/blood-2024-203827
Published: 2024
Journal Articles

TCL1A Is Associated with Blinatumomab Response and Immune Activation in Pediatric B-ALL

Free
Andrew Hughes, Rawan Shraim, Lahari Uppuluri, Haley Newman, Gongping Shi, Julie Asare, Theresa Ryan, Elizabeth A. Raetz, James A. Whitlock, Maureen M. O'Brien, Deepa Bhojwani, Rachel E. Rau, Kara L. Davis, Stacy Cooper, Patrick Brown, Stephen P. Hunger, Mignon L. Loh, Laura E. Hogan, Stephan A. Grupp, Jun J. Yang, David T. Teachey, Caroline Diorio
Journal: Blood
Blood (2024) 144 (Supplement 1): 634.
https://doi.org/10.1182/blood-2024-203756
Published: 2024
Journal Articles

A T-ALL order: a new risk classifier for T-ALL

Free
Clinical Trials & Observations
Haley Newman, David T. Teachey
Journal: Blood
Blood (2024) 144 (15): 1545–1547.
https://doi.org/10.1182/blood.2024025623
Published: 2024
Journal Articles

Survival Disparities By Frontline Clinical Trial Enrollment Status for Treatment of Pediatric Acute Myeloid Leukemia

Free
Daniel J. Zheng, Elsa van der Mei, Yimei Li, Yuan-Shung V. Huang, Catherine Aftandilian, Kira Bona, Emi Caywood, Anderson B. Collier, M. Monica Gramatges, Mallorie M. Heneghan, Meret Henry, Craig Lotterman, Kelly Maloney, Tamara P. Miller, Arunkumar Modi, Rajen Mody, Elaine Morgan, Naomi J. Winick, Jennifer J. Wilkes, Victor Wong, Haley Newman, Regina M. Myers, Caitlin W. Elgarten, Alix E. Seif, Brian T. Fisher, Richard Aplenc, Kelly D. Getz
Journal: Blood
Blood (2023) 142 (Supplement 1): 2430.
https://doi.org/10.1182/blood-2023-189240
Published: 2023
Journal Articles

Cancer Predisposition Genetic Testing Among Children with Hematologic Malignancies

Free
Haley Newman, Mary Egan Clark, Suzanne P MacFarland, Garrett M. Brodeur, Stephen P Hunger, Timothy S Olson, Jinhua Wu, Jeffrey Schubert, Netta Golenberg, Maha Patel, Elizabeth Denenberg, Elizabeth Fanning, Jiani Chen, Tamara Luke, Daniel Gallo, Kajia Cao, Weixian Fu, Zhiqian Fan, Minjie Luo, Lea Surrey, Gerald Wertheim, Marilyn M. Li, Yiming Zhong
Journal: Blood
Blood (2023) 142 (Supplement 1): 1458.
https://doi.org/10.1182/blood-2023-180008
Published: 2023
Journal Articles

Racial and Ethnic Differences in Acuity and Cumulative Frontline Organ Toxicity at the Time of Relapse in Pediatric Acute Myeloid Leukemia

Free
Daniel J. Zheng, Yimei Li, Yuan-Shung V. Huang, Catherine Aftandilian, Kira Bona, Emi Caywood, Anderson B. Collier, M. Monica Gramatges, Mallorie M. Heneghan, Meret Henry, Craig Lotterman, Kelly Maloney, Tamara P. Miller, Arunkumar Modi, Rajen Mody, Elaine Morgan, Naomi J. Winick, Jennifer J. Wilkes, Victor Wong, Cody Gathers, Haley Newman, Reneé H. Moore, Regina M. Myers, Caitlin W. Elgarten, Alix E. Seif, Brian T. Fisher, Richard Aplenc, Kelly D. Getz
Journal: Blood
Blood (2023) 142 (Supplement 1): 387.
https://doi.org/10.1182/blood-2023-180713
Published: 2023
Journal Articles

IL-10 Levels Differentially Regulate IFNg Signaling of CART19 and CART22

Free
Caroline Diorio, Regina M. Myers, Anastasia Frank-Kamenetski, Rawan Shraim, Amanda M. Dinofia, Zachary Martinez, Ohaila Mustafa, Joseph A Fraietta, Vanessa Gonzalez, Vivian Yi, Lahari Uppuluri, Haley Newman, Edward Behrens, Carl June, Scott Canna, Stephan Grupp, David T. Teachey
Journal: Blood
Blood (2023) 142 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2023-182377
Published: 2023
Journal Articles

PI3king apart a rare disease with targeted therapy

Free
Clinical Trials & Observations
Haley Newman, David T. Teachey
Journal: Blood
Blood (2023) 141 (9): 963–964.
https://doi.org/10.1182/blood.2022019105
Published: 2023
Journal Articles

Impact of poverty and neighborhood opportunity on outcomes for children treated with CD19-directed CAR T-cell therapy

Free
Clinical Trials & Observations
Haley Newman, Yimei Li, Hongyan Liu, Regina M. Myers, Vicky Tam, Amanda DiNofia, Lisa Wray, Susan R. Rheingold, Colleen Callahan, Claire White, Diane Baniewicz, Lena E. Winestone, Stephan Kadauke, Caroline Diorio, Carl H. June, Kelly D. Getz, Richard Aplenc, David T. Teachey, Shannon L. Maude, Stephan A. Grupp, Kira Bona, Allison Barz Leahy
Journal: Blood
Blood (2023) 141 (6): 609–619.
https://doi.org/10.1182/blood.2022017866
Published: 2023
Includes: Supplemental data