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Journal Articles

LDB1-dependent enhancer networks drive high-risk transcriptional programs in T-cell acute lymphoblastic leukemia

Rahul Bhansali, Juan Long, Petri Polonen, Shuo Zhang, Mariah Antopia, Siqing Wang, Nicholas Aboreden, Ahnaf Tausif, Zhuangzhuang Geng, Cheryl Keller, Belinda Giardine, Ross Hardison, Charles Mullighan, Gerd Blobel

Blood (2025) 146 (Supplement 1): 3251.

https://doi.org/10.1182/blood-2025-3251

Published: 2025

Journal Articles

Immunophenotypic identification of ETP-like T-ALL using CD1a, CD165 and CD184.

Monica Singh, David Westerman, Stuart Winter, Kimberly Dunsmore, David Teachey, Rawan Shraim, Petri Polonen, Charles Mullighan, Brent Wood

Blood (2025) 146 (Supplement 1): 3369.

https://doi.org/10.1182/blood-2025-3369

Published: 2025

Journal Articles

Effects of ZMIZ1 mutations in newly defined early T-cell precursor leukemia

Jannaldo Nieves-Salva, Sarah Khan, Francisco Gomez-Rivera, Elizabeth Choe, Karena Lin, Zeel Shukla, Jason Xu, David Teachy, Kai Tan, Charles Mullighan, Petri Polonen

Blood (2025) 146 (Supplement 1): 1589.

https://doi.org/10.1182/blood-2025-1589

Published: 2025

Journal Articles

Genomic determinants of treatment outcome and identification of a new genomic subset of adult acute lymphoblastic leukemia from the ECOG-ACRIN E1910 randomized phase III trial

Blood (2025) 146 (Supplement 1): 31.

https://doi.org/10.1182/blood-2025-31

Published: 2025

Journal Articles

Tallforest: Multi-omic classifier for T-lineage acute lymphoblastic leukemia

Petri Polonen, Yiping Fan, Shaohua Lei, Qingsong Gao, Yiming Wu, Ti-Cheng Chang, Haley Newman, Lahari Uppuluri, Niroshan Nadarajah, Torsten Haferlach, Marketa Zaliova, Jan Trka, Lu Wang, Hiroto Inaba, Stanley Pounds, Gang Wu, David Teachey, Charles Mullighan

Blood (2025) 146 (Supplement 1): 336.

https://doi.org/10.1182/blood-2025-336

Published: 2025

Journal Articles

Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98 -rearranged leukemia

Blood (2025) 146 (17): 2102–2118.

https://doi.org/10.1182/blood.2025028993

Published: 2025

Includes: Supplemental data

Journal Articles

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Blood (2025) 145 (23): 2685–2700.

https://doi.org/10.1182/blood.2024027270

Published: 2025

Includes: Supplemental data

Journal Articles

STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

Blood (2025) 145 (23): 2793–2798.

https://doi.org/10.1182/blood.2025028566

Published: 2025

Includes: Supplemental data

Journal Articles

Classification and risk stratification in T-lineage acute lymphoblastic leukemia

Petri Pölönen, Charles G. Mullighan, David T. Teachey

Blood (2025) 145 (14): 1464–1474.

https://doi.org/10.1182/blood.2023022920

Published: 2025

Journal Articles

A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

Blood (2024) 144 (Supplement 1): 2830.

https://doi.org/10.1182/blood-2024-198354

Published: 2024

Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Blood (2024) 144 (Supplement 1): 1464.

https://doi.org/10.1182/blood-2024-211090

Published: 2024

Journal Articles

Refined Immunophenotypic Criteria Using CD184 and CD165 Improves Sensitivity of Identification of ETP T-ALL

Monica Singh, David Westerman, Stuart S. Winter, Kimberly P. Dunsmore, David T. Teachey, Rawan Shraim, Petri Pölönen, Charles G. Mullighan, Brent L. Wood

Blood (2024) 144 (Supplement 1): 5923.

https://doi.org/10.1182/blood-2024-209533

Published: 2024

Journal Articles

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Blood (2024) 144 (Supplement 1): 313.

https://doi.org/10.1182/blood-2024-203827

Published: 2024

Journal Articles

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Masayuki Umeda, Nicole L Michmerhuizen, Ryan Hiltenbrand, Juan M Barajas, Bright Arthur, Michael P Walsh, Guangchun Song, Jing Ma, Tamara Westover, Petri Pölönen, Cristina Mecucci, Danika Di Giacomo, Franco Locatelli, Riccardo Masetti, Salvatore Bertuccio, Martina Pigazzi, Ilaria Iacobucci, Charles G. Mullighan, Jeffery M Klco

Blood (2024) 144 (Supplement 1): 325.

https://doi.org/10.1182/blood-2024-210208

Published: 2024

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

Journal Articles

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

Blood (2023) 141 (13): 1610–1625.

https://doi.org/10.1182/blood.2021011094

Published: 2023

Includes: Supplemental data

Journal Articles

The Influence of Genetic Ancestry on Disease Biology in Pediatric T-Cell Acute Lymphoblastic Leukemia

Blood (2022) 140 (Supplement 1): 3458–3460.

https://doi.org/10.1182/blood-2022-159159

Published: 2022

Journal Articles

Single-Cell Functional Genomics of Natural Killer Cell Interaction with Blood Cancers

Blood (2022) 140 (Supplement 1): 8343–8344.

https://doi.org/10.1182/blood-2022-167535

Published: 2022

Journal Articles

Erythroid/Megakaryocytic Differentiation Confers BCL-XL Dependency and Venetoclax Resistance in Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 101–103.

https://doi.org/10.1182/blood-2022-158694

Published: 2022

Journal Articles

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

Blood (2022) 140 (Supplement 1): 1727–1729.

https://doi.org/10.1182/blood-2022-167157

Published: 2022

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LDB1-dependent enhancer networks drive high-risk transcriptional programs in T-cell acute lymphoblastic leukemia

Immunophenotypic identification of ETP-like T-ALL using CD1a, CD165 and CD184.

Effects of ZMIZ1 mutations in newly defined early T-cell precursor leukemia

Genomic determinants of treatment outcome and identification of a new genomic subset of adult acute lymphoblastic leukemia from the ECOG-ACRIN E1910 randomized phase III trial

Tallforest: Multi-omic classifier for T-lineage acute lymphoblastic leukemia

Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98 -rearranged leukemia

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

Classification and risk stratification in T-lineage acute lymphoblastic leukemia

A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Refined Immunophenotypic Criteria Using CD184 and CD165 Improves Sensitivity of Identification of ETP T-ALL

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

The Influence of Genetic Ancestry on Disease Biology in Pediatric T-Cell Acute Lymphoblastic Leukemia

Single-Cell Functional Genomics of Natural Killer Cell Interaction with Blood Cancers

Erythroid/Megakaryocytic Differentiation Confers BCL-XL Dependency and Venetoclax Resistance in Acute Myeloid Leukemia

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

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American Society of Hematology

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