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Journal Articles

Hypomethylating agent with venetoclax versus hypomethylating agent alone in frontline management of myelodysplastic syndrome - impact of subgroups on clinical outcomes

Free
Guru Subramanian Guru Murthy, Yasmin Abaza, Somedeb Ball, Ramzi Abboud, Michael Haddadin, Jonathan Feld, Suresh Kumar Balasubramanian, Ashwin Kishtagari, Adam Cohen-Nowak, Veronica Guerra, Hayley Hawkins, Asmita Shukla, Virginia Tan, Dominika Dulak, Reema Tawfiq, Emily Dworkin, Julian Weiss, Amber Feng, Jesus Gonzalez-Lugo, Prajwal Dhakal, Jessica Leonard, Charles Foucar, Talha Badar, Rory Shallis, Annie Im, Shyam Patel, Chenyu Lin, Anand Patel, Eric Winer, Ehab Atallah, Rami Komrokji
Journal: Blood
Blood (2025) 146 (Supplement 1): 239.
https://doi.org/10.1182/blood-2025-239
Published: 2025
Journal Articles

Asciminib as initial therapy with addition of lower dose tyrosine kinase inhibitors (TKIs) for patients with chronic myeloid leukemia who do not achieve optimal response or a deep molecular remission

Free
James Thompson, Lisa Rein, Michael Mauro, Srinivas Tantravahi, Jay Yang, Arielle Baim, Sonia Maldonado-Schmidt, Claire Olig, Kathryn Flynn, Yan Gao, Jerald Radich, Ehab Atallah, Jorge Cortes
Journal: Blood
Blood (2025) 146 (Supplement 1): 7311.
https://doi.org/10.1182/blood-2025-7311
Published: 2025
Journal Articles

Real world outcomes of patients with CML-CP treated with tyrosine kinase inhibitors from the h. jean khoury cure CML consortium (HJKC3)

Free
Ehab Atallah, Emily Giever, Jorge Cortes, Ryan Conrardy, Lisa Rein, Arielle Baim, Idayat Akinola, James Thompson, Yan Gao, Richard Larson, Ravi Bhatia, B. Douglas Smith, Kathryn Flynn
Journal: Blood
Blood (2025) 146 (Supplement 1): 2844.
https://doi.org/10.1182/blood-2025-2844
Published: 2025
Journal Articles

Choice of hypomethylating agent for newly diagnosed TP53-mutant Acute Myeloid Leukemia: A command registry study

Free
Talha Badar, Omer Jamy, Chenyu Lin, Anand Patel, Yu-Hung Wang, Rory Shallis, Kendall Diebold, Alex Coltoff, Aaron Goldberg, Jan Philipp Bewersdorf, Kenneth Zabel, Charles Foucar, Yasmin Abaza, Guru Subramanian Guru Murthy, Neil Palmisiano, Adam Duvall, Vamsi Kota, Shyam Patel, Amer Zeidan, Ehab Atallah, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 874.
https://doi.org/10.1182/blood-2025-874
Published: 2025
Journal Articles

Bone marrow biopsy characteristics at nadir after intensive induction therapy do not predict outcomes in acute myeloid leukemia (AML): An analysis of ECOG-ACRIN clinical trials

Free
Douglas Tremblay, Li Chen, Zhuoxin Sun, Chezi Ganzel, Hugo Fernandez, James Foran, Daniel Arber, Hillard Lazarus, Yanming Zhang, Elisabeth Paietta, John Bennett, Jacob Rowe, Mark Litzow, Martin Tallman, Ehab Atallah, Selina Luger
Journal: Blood
Blood (2025) 146 (Supplement 1): 871.
https://doi.org/10.1182/blood-2025-871
Published: 2025
Journal Articles

SWOG 1318: Combination of dasatinib, prednisone, and blinatumomab for older patients with Philadelphia chromosome positive acute lymphoblastic leukemia:  longer follow up and predictors of outcomes

Free
Anjali Advani, Anna Moseley, Kristen O'Dwyer, Cecilia Yeung, Olga Sala Torra, Brent Wood, Jae Park, Matthew Wieduwilt, Deepa Jeyakumar, George Yaghmour, Ehab Atallah, Aaron Gerds, Susan O'Brien, Jane Liesveld, Megan Othus, Mark Litzow, Richard Stone, Jerald Radich, Harry Erba
Journal: Blood
Blood (2025) 146 (Supplement 1): 3343.
https://doi.org/10.1182/blood-2025-3343
Published: 2025
Journal Articles

Hairy cell leukemia treatment strategies: A real-world multicenter experience

Free
James Fradin, Lisa Rein, Aniko Szabo, Karen-Sue Carlson, Talha Badar, Troy Holden, Shiv Shah, Annie Im, Anand Patel, Ehab Atallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 1802.
https://doi.org/10.1182/blood-2025-1802
Published: 2025
Journal Articles

Treatment free remission after asciminib (ABL001) based therapy in chronic Phase chronic myeloid leukemia (CP-CML) patients who relapsed after a prior attempt at TKI discontinuation-h jean khoury cure CML consortium study HJKC3-0003

Free
Michael Mauro, Lisa Rein, Jay Yang, Srinivas Tantravahi, Sonia Maldonado-Schmidt, Claire Olig, Alexander Hinman, Arielle Baim, Jerald Radich, Kathryn Flynn, Ehab Atallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 7293.
https://doi.org/10.1182/blood-2025-7293
Published: 2025
Journal Articles

Toxicities on the E1910 phase III randomized trial of blinatumomab plus chemotherapy in adults with BCR:ABL-1 negative acute lymphoblastic leukemia

Free
Anjali Advani, Li Chen, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Dan Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 5120.
https://doi.org/10.1182/blood-2025-5120
Published: 2025
Journal Articles

The predictive value of the interleukin 2 receptor (IL2)/ferritin ratio in the diagnosis of lymphoma associated hemophagocytic lymphohistiocytosis (LAHS): A United States, multi center experience

Free
Dariusz Uczkowski, Linzi Hobbs-Parker, Stephanie Yohay, Adarsh Ettyreddy, Natalia Gontarczyk Uczkowski, Chenyu Lin, Alexander Coltoff, Laura Michaelis, Lisa Baumann Kreuziger, Nirav Shah, Ehab Atallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 4769.
https://doi.org/10.1182/blood-2025-4769
Published: 2025
Journal Articles

Impact of therapy delays on outcomes in adults with BCR::ABL1 negative b-lineage acute lymphoblastic leukemia (ALL) in the ECOG-ACRIN E1910 trial randomized to conventional chemotherapy +/- blinatumomab

Free
Bhavana Bhatnagar, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1549.
https://doi.org/10.1182/blood-2025-1549
Published: 2025
Journal Articles

Asciminib (ASC) in chronic myeloid leukemia in chronic Phase (CML-CP): Interim analysis (IA) efficacy and safety results of the Phase 2 ASC2ESCALATE trial in the cohort of newly diagnosed (1L) patients (pts)

Free
Moshe Levy, David Andorsky, CelesteAnn Bremer, Joshua Zeidner, Neil Palmisiano, Steven McCune, Anthony Hunter, Zohra Nooruddin, Haifaa Abdulhaq, Vivian Oehler, Shaker Dakhil, Brian Mulherin, Gustavo Fonseca, Michael Heinrich, Omer Jamy, Paul Koller, Koji Sasaki, Islam Mohamad Sadek, Daisy Yang, Dramane Laine, John (randy) Sabo, Amanda Hall, Dheeraj Gianchandani, Michael Mauro, Jorge Cortes, Ehab Atallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 3775.
https://doi.org/10.1182/blood-2025-3775
Published: 2025
Journal Articles

Real-world practice patterns of IDH inhibitors and outcomes of on-label IDH inhibitor use for Acute Myeloid Leukemia in the United States

Free
Chenyu Lin, Ashley Woods, Zhiguo Li, Sami Leone, Emily Dworkin, Justin Kahla, Moiez Ali, Nepheli Raptis, Yasmin Abaza, Alifya Lokhandwala, Cilomar Martins de Oliveira Filho, Michelle Lee, Cristian Taborda, Jan Philipp Bewersdorf, Jordan Ritchie, Alexander Coltoff, Sean Ormond, Madelyn Burkart, Dominika Dulak, Annie Im, Mahesh Kumar, Amy Song, Sunil Iyer, Guru Subramanian Guru Murthy, Katherine Zhou, Micaela Scobie, Jessica Lewis-Gonzalez, Charles Foucar, Ehab Atallah, Eric Winer, Harry Erba, Thomas LeBlanc, E. Dianne Pulte, Joseph Wynne, Anand Patel, Talha Badar, Kelly Norsworthy
Journal: Blood
Blood (2025) 146 (Supplement 1): 1614.
https://doi.org/10.1182/blood-2025-1614
Published: 2025
Journal Articles

Asciminib (ASC) in chronic myeloid leukemia in chronic Phase (CML-CP): Efficacy and safety results of the Phase 2 ASC2ESCALATE trial in the cohort of patients (pts) with 1 prior tyrosine kinase inhibitor (TKI)

Free
Jorge Cortes, Ehab Atallah, David Andorsky, Marlise Luskin, Srinivas Tantravahi, Koji Sasaki, James Dugan, CelesteAnn Bremer, Vivian Oehler, Joshua Zeidner, Moshe Levy, Camille Abboud, Paul Koller, Bonnie Kiner-Strachan, Habte Yimer, Islam Mohamad Sadek, Daisy Yang, Dramane Laine, John (randy) Sabo, Bridget Cooper, Ennan Gu, Michael Mauro
Journal: Blood
Blood (2025) 146 (Supplement 1): 906.
https://doi.org/10.1182/blood-2025-906
Published: 2025
Journal Articles

Management and outcomes of patients diagnosed with chronic myeloid leukemia in blast Phase: A multicenter analysis by the h jean khoury cure CML consortium

Free
Akriti Jain, Umar Iqbal, Colin Vale, Anthony Hunter, Wei Wei, Kinaya Smith, Shivani Handa, Allyson Waller, Alice Mims, Benjamin McCormick, Genevieve Crane, Ling Zhang, Asmita Shukla, Jay Yang, Amanda Dailey-Hansen, Srinivas Tantravahi, Suravi Raychaudhuri, Vivian Oehler, Jerald Radich, B. Douglas Smith, Nhi Nai, Charles Foucar, Onyee Chan, Javier Pinilla-Ibarz, Michael Deininger, Talha Badar, Sudipto Mukherjee, Kendra Sweet, Ehab Atallah, Zhuoer Xie
Journal: Blood
Blood (2025) 146 (Supplement 1): 904.
https://doi.org/10.1182/blood-2025-904
Published: 2025
Journal Articles

Real-world analysis of asciminib as first-line therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase: A chart review Study in the United States

Free
Ehab Atallah, Islam Mohamad Sadek, Emily McGovern, Dominick Latremouille-Viau, Carmine Rossi, Remi Bellefleur, Gabriel Marquez, Annie Guerin, Daisy Yang, David Wei
Journal: Blood
Blood (2025) 146 (Supplement 1): 8178.
https://doi.org/10.1182/blood-2025-8178
Published: 2025
Journal Articles

Cladribine based salvage chemotherapy in AML patients with persistent or recurrent disease after venetoclax/HMA

Free
Sameem Abedin, Guru Subramanian Guru Murthy, Karen-Sue Carlson, Lyndsey Runaas, Walter Longo, Laura Michaelis, Ehab Atallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 5238.
https://doi.org/10.1182/blood-2025-5238
Published: 2025
Journal Articles

Clinical and molecular characteristics of Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia with central nervous system relapse versus systemic relapse: Results from consortium on myeloid malignancies and neoplastic diseases (COMMAND)

Free
Rafael Madero-Marroquin, Ravi Kishore Narra, Alice Mims, Alexander Coltoff, Georgio Medawar, Brooke Hisrich, Rory Shallis, Cameron Hunter, Vamsi Kota, Tamer Othman, Brian Jonas, Shreya Desai, Guilherme Sacchi De Camargo Correia, Adam Duvall, Neil Palmisiano, Emily Curran, Zulfa Omer, Anjali Advani, Ehab Atallah, Mark Litzow, Anand Patel, Talha Badar
Journal: Blood
Blood (2025) 146 (Supplement 1): 3320.
https://doi.org/10.1182/blood-2025-3320
Published: 2025
Journal Articles

Myeloid malignancies molecular analysis for therapy choice (myeloMATCH): Rapid availability of clinical, pathologic and molecular features for treatment assignment in the first 550 patients.

Free
Eric Winer, Megan Othus, Ehab Atallah, Stephanie Tsai, Mitchell Sabloff, Afaf Osman, Annie Im, Sanam Loghavi, Anna Moseley, Brent Wood, Min Fang, Cecilia Yeung, Xueyan Chen, Xiaoyu QU, Lyndsay Harris, Sayak Ghatak, Steven Gore, Geoffrey Uy, Laura Michaelis, Olatoyosi Odenike, Richard Stone, Selina Luger, Sarit Assouline, Harry Erba, Mark Litzow, Curtis Lachowiez, John Reagan, Uma Borate, Mary Lynn Savoie, Brian Jonas, Ntasha Roy, Jerald Radich, Richard Little, Shahanawaz Jiwani
Journal: Blood
Blood (2025) 146 (Supplement 1): 5279.
https://doi.org/10.1182/blood-2025-5279
Published: 2025
Journal Articles

A comparison of real-world outcomes of asciminib versus ATP-competitive tyrosine kinase inhibitors as second-line treatment in patients with chronic myeloid leukemia in chronic phase

Free
Ehab Atallah, Islam Mohamad Sadek, Emily McGovern, Dominick Latremouille-Viau, Carmine Rossi, Remi Bellefleur, Nathan Gobeil, Gabriel Marquez, Annie Guerin, Daisy Yang, David Wei
Journal: Blood
Blood (2025) 146 (Supplement 1): 724.
https://doi.org/10.1182/blood-2025-724
Published: 2025