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Journal Articles

Choice of hypomethylating agent for newly diagnosed TP53-mutant Acute Myeloid Leukemia: A command registry study

Free
Talha Badar, Omer Jamy, Chenyu Lin, Anand Patel, Yu-Hung Wang, Rory Shallis, Kendall Diebold, Alex Coltoff, Aaron Goldberg, Jan Philipp Bewersdorf, Kenneth Zabel, Charles Foucar, Yasmin Abaza, Guru Subramanian Guru Murthy, Neil Palmisiano, Adam Duvall, Vamsi Kota, Shyam Patel, Amer Zeidan, Ehab Atallah, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 874.
https://doi.org/10.1182/blood-2025-874
Published: 2025
Journal Articles

Ziftomenib in combination with venetoclax and azacitidine in newly diagnosed NPM1-m acute myeloid leukemia: Phase 1b results from KOMET-007

Free
Gail Roboz, Eunice Wang, Amir Fathi, Harry Erba, Keith Pratz, Guru Subramanian Guru Murthy, Leonard Alsfeld, James Blachly, Kiran Naqvi, Ghayas Issa, Ayman Qasrawi, Stephen Strickland, Neil Palmisiano, Jessica Altman, Cecilia Arana Yi, Grerk Sutamtewagul, Yazan Madanat, Suresh Kumar Balasubramanian, Christine McMahon, Hongling Zhang, Tianle Chen, Marcie Riches, Daniel Corum, Mollie Leoni, Amer Zeidan
Journal: Blood
Blood (2025) 146 (Supplement 1): 766.
https://doi.org/10.1182/blood-2025-766
Published: 2025
Journal Articles

Ziftomenib in combination with venetoclax and azacitidine in relapsed/refractory NPM1-m or KMT2A-r acute myeloid leukemia: Updated phase 1a/b safety and clinical activity results from KOMET-007

Free
Ghayas Issa, Amir Fathi, Amer Zeidan, Harry Erba, Gail Roboz, Jessica Altman, Keith Pratz, Mark Juckett, Tara Lin, Suresh Kumar Balasubramanian, Anjali Advani, Gary Schiller, Neil Palmisiano, Marcello Rotta, Stephen Strickland, Christine McMahon, Yazan Madanat, Talha Badar, Mohamad Khawandanah, George Yaghmour, James McCloskey, James Mangan, Antoine Saliba, Ivana Gojo, Diaa Osman, Hongling Zhang, Ying Tian, Marcie Riches, Daniel Corum, Mollie Leoni, Eunice Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 764.
https://doi.org/10.1182/blood-2025-764
Published: 2025
Journal Articles

Monotherapy update from Phase 1 portion in Phase1/2 trial of the menin-MLL inhibitor enzomenib (DSP-5336) in patients with relapsed or refractory acute leukemia

Free
Naval Daver, Joshua Zeidner, Justin Watts, Junichiro Yuda, Mark Levis, Pau Montesinos, Cristina Papayannidis, Kentaro Fukushima, Takahiro Shima, Emmanuel Raffoux, Uma Borate, Neil Palmisiano, Joseph Brandwein, Mael Heiblig, Yasushi Miyazaki, Takayuki Ikezoe, Melissa Ooi, Shang-Ju Wu, Eunice Wang, Susana Vives, Stephen Strickland, Dimitri Breems, Naoko Hosono, Yoshiaki Ogawa, Koichi Onodera, Andrew Brunner, Gina Keiffer, Timothy Pardee, Paul Shami, Alireza Eghtedar, Hongliang Cai, Bo Xu, Priya Robson, Akinobu Watanabe, Matthew Hitron, Jatin Shah, Hagop Kantarjian, Harry Erba
Journal: Blood
Blood (2025) 146 (Supplement 1): 763.
https://doi.org/10.1182/blood-2025-763
Published: 2025
Journal Articles

Trial in progress: A phase I study evaluating the safety of cirtuvivint (CIRT) as monotherapy and in combination with ASTX727 in patients with myelodysplastic syndromes (MDS) and Acute Myeloid Leukemia (AML)

Free
Evan Chen, Yiwen Liu, Eytan Stein, Brian Ball, Ivana Gojo, Olatoyosi Odenike, Neil Palmisiano, Vu Duong, Zimu Gong, Michael Hochman, Carine Bossard, John Hill, Mirta Grifman, Daniel Deangelo, Richard Stone, Ilene Galinsky, Rebecca Leonard, Richard Little, Steven Gore, Jan Philipp Bewersdorf, Lourdes Mendez, Nikolai Podoltsev, Amer Zeidan, Omar Abdel-Wahab, Maximilian Stahl
Journal: Blood
Blood (2025) 146 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2025-3431
Published: 2025
Journal Articles

Asciminib (ASC) in chronic myeloid leukemia in chronic Phase (CML-CP): Interim analysis (IA) efficacy and safety results of the Phase 2 ASC2ESCALATE trial in the cohort of newly diagnosed (1L) patients (pts)

Free
Moshe Levy, David Andorsky, CelesteAnn Bremer, Joshua Zeidner, Neil Palmisiano, Steven McCune, Anthony Hunter, Zohra Nooruddin, Haifaa Abdulhaq, Vivian Oehler, Shaker Dakhil, Brian Mulherin, Gustavo Fonseca, Michael Heinrich, Omer Jamy, Paul Koller, Koji Sasaki, Islam Mohamad Sadek, Daisy Yang, Dramane Laine, John (randy) Sabo, Amanda Hall, Dheeraj Gianchandani, Michael Mauro, Jorge Cortes, Ehab Atallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 3775.
https://doi.org/10.1182/blood-2025-3775
Published: 2025
Journal Articles

Preliminary safety and efficacy of the frida study: Iadademstat and gilteritinib in FLT3-mutated relapsed/refractory acute myeloid leukemia

Free
Sangeetha Venugopal, Neil Palmisiano, Guru Subramanian Guru Murthy, Theodore Braun, Alex Ambinder, Jonathan Feld, Sharad Khurana, Stephen Strickland, Rajneesh Nath, Konstantinos Sdrimas, Raquel Ruiz, Beatriz Bruno, Sonia Gutierrez, Douglas Faller, Ana Limon, Amir Fathi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5197.
https://doi.org/10.1182/blood-2025-5197
Published: 2025
Journal Articles

Clinical and molecular characteristics of Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia with central nervous system relapse versus systemic relapse: Results from consortium on myeloid malignancies and neoplastic diseases (COMMAND)

Free
Rafael Madero-Marroquin, Ravi Kishore Narra, Alice Mims, Alexander Coltoff, Georgio Medawar, Brooke Hisrich, Rory Shallis, Cameron Hunter, Vamsi Kota, Tamer Othman, Brian Jonas, Shreya Desai, Guilherme Sacchi De Camargo Correia, Adam Duvall, Neil Palmisiano, Emily Curran, Zulfa Omer, Anjali Advani, Ehab Atallah, Mark Litzow, Anand Patel, Talha Badar
Journal: Blood
Blood (2025) 146 (Supplement 1): 3320.
https://doi.org/10.1182/blood-2025-3320
Published: 2025
Journal Articles

Phase II Results of ECOG-ACRIN EA9152: A multicenter study of liposomal vincristine (L-VCR) or vincristine sulfate (VCR) and venetoclax (VEN) in relapsed or refractory acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL)

Free
Neil Palmisiano, Juwhei Lee, David Claxton, Elisabeth Paietta, Nikolai Podoltsev, Jae Park, Dale Schaar, Jonathan Webster, Selina Luger, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1577.
https://doi.org/10.1182/blood-2025-1577
Published: 2025
Journal Articles

Comparable Survival of Treatment Naïve TP53 Mutated Acute Myeloid Leukemia Treated with Hypomethylating Agent Compared to Hypomethylating Agent Plus Venetoclax Based Therapy

Free
Talha Badar, Ehab L. Atallah, Rory M. Shallis, Anand Ashwin Patel, Guilherme Sacchi De Camargo Correia, Aaron D. Goldberg, Antoine Saliba, Jan Philipp Bewersdorf, Adam S Duvall, Danielle Bradshaw, Yasmin Abaza, Guru Subramanian Guru Murthy, Neil Palmisiano, Vamsi K. Kota, Mark R. Litzow
Journal: Blood
Blood (2023) 142 (Supplement 1): 592.
https://doi.org/10.1182/blood-2023-184626
Published: 2023
Journal Articles

Achievement of Undetectable BCR::ABL1 (uBCR::ABL1) Is Predictive of Improved Survival in Philadelphia Chromosome Positive (Ph+ve) Acute Lymphoblastic Leukemia (ALL) Patients Not Receiving Allogeneic Stem Cell Transplantation

Free
Talha Badar, Ravi Narra, Alice Mims, Rory M. Shallis, Guilherme Sacchi De Camargo Correia, Cameron Hunter, Vamsi K. Kota, Shreya Desai, Anand Ashwin Patel, Adam S Duvall, Neil Palmisiano, Emily K Curran, Omer Zulfa, Anjali S. Advani, Ehab L. Atallah, Mark R. Litzow
Journal: Blood
Blood (2023) 142 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2023-188188
Published: 2023
Journal Articles

A Phase Ib/II Study Evaluating Navitoclax after Failure of Hypomethylating Agent and Venetoclax for Treatment of Relapsed or Refractory High-Risk Myelodysplastic Syndrome

Free
Gina Keiffer, Sara E. Meyer, Christine Eischen, Ubaldo Martinez Outschoorn, Onder Alpdogan, Adam F. Binder, Pierluigi Porcu, Lindsay Wilde, Margaret Kasner, Neil Palmisiano
Journal: Blood
Blood (2023) 142 (Supplement 1): 1551.
https://doi.org/10.1182/blood-2023-186765
Published: 2023
Journal Articles

No Place like Home: Home-Based Intravenous Arsenic Trioxide for the Treatment of Acute Promyelocytic Leukemia (APL)

Free
Brooke Kania, David Awad, Michael Kane, Andrew M Evens, Neil Palmisiano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2357.
https://doi.org/10.1182/blood-2023-190597
Published: 2023
Journal Articles

Predictors of Long-Term Outcome in TP53 -Mutated Acute Myeloid Leukemia Patients Receiving Allogeneic Stem Cell Transplant after First- or Second-Line Therapy: Results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

Free
Talha Badar, Ehab L. Atallah, Rory Michael Shallis, Antoine N. Saliba, Maximilian F. Stahl, Jan Philipp Bewersdorf, Justin Grenet, Anand Ashwin Patel, Yasmin Abaza, Guru Subramanian Guru Murthy, Adam S Duvall, Madelyn Burkart, Neil Palmisiano, Michal Jakub Kubiak, Vamsi K. Kota, Shira Dinner, Aaron D Goldberg, Mark R. Litzow
Journal: Blood
Blood (2022) 140 (Supplement 1): 1435–1437.
https://doi.org/10.1182/blood-2022-167731
Published: 2022
Journal Articles

Smoking and Its Prognostic Effect on Survival in Patients with TP53 Mutated MDS

Free
Sean Patrick Reilly, Xia Bi, Zachary French, Lindsay Wilde, Neil Palmisiano
Journal: Blood
Blood (2022) 140 (Supplement 1): 12339–12340.
https://doi.org/10.1182/blood-2022-164712
Published: 2022
Journal Articles

Assessment of Concurrent Personal and Family History of Hematologic Malignancies in Patients Referred for Genetic Counseling at Thomas Jefferson University Hospital (TJUH), Sidney Kimmel Cancer Center (SKCC) from 2014-2021

Free
Molly Halloran, Gina Keiffer, Veda Giri, Laura Gross, Lindsay Wilde, Neil Palmisiano, Pierluigi Porcu, Margaret Kasner
Journal: Blood
Blood (2022) 140 (Supplement 1): 11466–11467.
https://doi.org/10.1182/blood-2022-165510
Published: 2022
Journal Articles

Clinical Outcomes of Patients with TP53 -Mutated AML after First Relapse or with Primary Refractory Disease: Results from Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

Free
Talha Badar, Ehab L. Atallah, Antoine N. Saliba, Rory Michael Shallis, Maximilian F. Stahl, Jan Philipp Bewersdorf, Guillerhme Sacchi De Camargo Correia, Anand Ashwin Patel, Yasmin Abaza, Guru Subramanian Guru Murthy, Adam S Duvall, Madelyn Burkart, Neil Palmisiano, Danielle Bradshaw, Vamsi K. Kota, Shira Dinner, Aaron D Goldberg, Mark R. Litzow
Journal: Blood
Blood (2022) 140 (Supplement 1): 6058–6060.
https://doi.org/10.1182/blood-2022-163795
Published: 2022
Journal Articles

Randomized Phase II Study to Assess the Role of Nivolumab As Single Agent to Eliminate Minimal Residual Disease and Maintain Remission in Acute Myelogenous Leukemia (AML) Patients after Chemotherapy (NCI9706 protocol; REMAIN Trial)

Free
Hongtao Liu, Elad Sharon, Theodore G. Karrison, Yuanyuan Zha, Noreen Fulton, Howard Streicher, Kendra Sweet, George Yaghmour, Jane Jijun Liu, Brian A. Jonas, Aaron D. Schimmer, Steven Grant, Amer M. Zeidan, Gerhard C. Hildebrandt, Christopher S. Hourigan, Christopher H. Lowrey, Ryan J. Mattison, Neil Palmisiano, Amandeep Salhotra, Dimitrios Tzachanis, Maria R. Baer, Tara L. Lin, Prapti Patel, Helen Chen, Walter M. Stadler, Olatoyosi Odenike, Richard A. Larson, Thomas F. Gajewski, Wendy Stock
Journal: Blood
Blood (2022) 140 (Supplement 1): 1716–1719.
https://doi.org/10.1182/blood-2022-157326
Published: 2022
Journal Articles

Outpatient Vyxeos Induction without Planned Admission for Select Patients with Secondary Acute Myeloid Leukemia (sAML): A Multicenter Analysis of Safety and Healthcare Resource Utilization

Free
Gina Keiffer, Guneet Kaleka, Caspian Oliai, Lindsay Wilde, Neil Palmisiano, Margaret Kasner
Journal: Blood
Blood (2022) 140 (Supplement 1): 3320–3321.
https://doi.org/10.1182/blood-2022-170710
Published: 2022
Journal Articles

A Large Multicenter Real-World Evidence (RWE) Analysis of Autoimmune (AI) Diseases and Lymphoma: Histologic Associations, Disease Characteristics, Survival, and Prognostication

Free
Jordan Carter, Adam J. Olszewski, Tatyana A. Feldman, Reem Karmali, Jean L. Koff, Sabarish Ayyappan, Matthew A. Lunning, Shazia Nakohda, Nadia Khan, Aryeh Pelcovits, Jason Lofters, Timothy Seijung Oh, Colin Burke O'Leary, Kittika Poonsombudlert, Carman Tong, Elaine Kuhn, Mingen Liu, Andrea Anampa-Guzman, Megha Shalavadi, Colin Thomas, Melissa Kives, Ning C. Dong, Alexander Hershey, Neil Palmisiano, Alexey V. Danilov, Francisco J. Hernandez-Ilizaliturri, Stefan K. Barta, Frederick Lansigan, Kerry J. Savage, Andrew M. Evens
Journal: Blood
Blood (2021) 138 (Supplement 1): 50.
https://doi.org/10.1182/blood-2021-149728
Published: 2021