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Journal Articles

SRSF2 mutation-induced CHD8 exon skipping represents a novel pathogenic mediator and therapeutic dependence in chronic myelomonocytic leukemia (CMML)

Yu-Hung Wang, Kristian Gurashi, Laura Guest, Roberto Paredes, Carlos Rivera, Luciano Nicosia, Shalini Sankar, David Walter, Curtis Hart, Sylvie Lachmann, Wei-Hsiang Lin, Antony Adamson, Kiran Batta, Daniel Wiseman

Blood (2025) 146 (Supplement 1): 676.

https://doi.org/10.1182/blood-2025-676

Published: 2025

Journal Articles

Refining the prognostic hierarchy of TP53 multihit alterations and isolated deletion of chromosome 5q in myelodysplastic syndromes

Blood (2025) 146 (Supplement 1): 2068.

https://doi.org/10.1182/blood-2025-2068

Published: 2025

Journal Articles

Myelodysplastic/myeloproliferative overlap neoplasms: Clinicopathological features, treatment strategies, and outcomes — a UK multicentre cohort Study

Blood (2025) 146 (Supplement 1): 7365.

https://doi.org/10.1182/blood-2025-7365

Published: 2025

Journal Articles

Investigating the clonal and biological underpinnings of systemic mastocytosis with an associated hematological neoplasm

Nana Adjoa Ben-Crentsil, Somedeb Ball, Hannah Newman, Christopher Ryder, Surendra Neupane, Anthony Hunter, Yu-Hung Wang, Kiran Batta, Kristian Gurashi, Traci Kruer, Maria Balasis, Ariel Quintana, Rami Komrokji, David Sallman, Andrew Kuykendall, Tracy George, Daniel Wiseman, Eric Padron

Blood (2025) 146 (Supplement 1): 3763.

https://doi.org/10.1182/blood-2025-3763

Published: 2025

Journal Articles

Choice of hypomethylating agent for newly diagnosed TP53-mutant Acute Myeloid Leukemia: A command registry study

Blood (2025) 146 (Supplement 1): 874.

https://doi.org/10.1182/blood-2025-874

Published: 2025

Journal Articles

Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS

Blood (2025) 146 (Supplement 1): 115.

https://doi.org/10.1182/blood-2025-115

Published: 2025

Journal Articles

Genomic and transcriptomic characterization of acute myeloid leukemia with CD123 overexpression

Chi-Yuan Yao, Chia-Lang Hsu, Yi-Tsung Yang, Feng-Ming Tien, Chien-Chin Lin, Yu-Hung Wang, Xavier Cheng-Hong Tsai, Wan Hsuan Lee, Hsin-An Hou, Hwei-Fang Tien, Wen-Chien Chou

Blood (2025) 146 (Supplement 1): 7013.

https://doi.org/10.1182/blood-2025-7013

Published: 2025

Journal Articles

Redefining the myeloid disease continuum: Machine learning–based development and validation of an integrated multimodal classification of myeloid neoplasms

Yu-Hung Wang, Kristian Gurashi, Chien-Chin Lin, Carmelo Gurnari, Hussein Awada, Adrian Mosquera, Manuel Perez Encinas, Donal McLornan, Andrius Zucenka, Talha Badar, Bor-Sheng Ko, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Nick Telford, Kiran Batta, Daniel Wiseman

Blood (2025) 146 (Supplement 1): 4347.

https://doi.org/10.1182/blood-2025-4347

Published: 2025

Journal Articles

Incorporating TET2 Variant Allele Frequency Enhances Prognostication in CMML: Insights from 849 Patients across Multiple Institutions

Yu-Hung Wang, Dorothée Selimoglu-Buet, Carmelo Gurnari, Andres Jerez, Andrius Zucenka, Chi-Yuan Yao, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Eric Solary, Kiran Batta, Daniel H Wiseman

Blood (2024) 144 (Supplement 1): 4579.

https://doi.org/10.1182/blood-2024-194319

Published: 2024

Journal Articles

Newly Developed Prognostic Score for Myelodysplastic Syndrome (MDS) with Isolated 5q Deletion (IPSS-del(5q))

Blood (2024) 144 (Supplement 1): 666.

https://doi.org/10.1182/blood-2024-194405

Published: 2024

Journal Articles

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Luca Lanino, Anthony M. Hunter, Nico Gagelmann, Marie Robin, Claudia Sala, Daniele Dall'Olio, Carmelo Gurnari, Lorenzo Dall'Olio, Yu-Hung Wang, Lisa Pleyer, Blanca Xicoy, Guillermo Montalban-Bravo, Lee-Yung Shih, Tamanna Haque, Omar Abdel-Wahab, Klaus Geissler, Alex Bataller, Alexandre Bazinet, Manja Meggendorfer, Ilaria Carola Casetti, Elisabetta Sauta, Erica Travaglino, Laura Palomo, Lurdes Zamora, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Esperanza Such, Guillermo Sanz, Anne Sophie Kubasch, Cristina Castilla-Llorente, Claude-Éric Bulabois, Laetitia Souchet, Hussein Awada, Massimo Bernardi, Patrizia Chiusolo, Antonio Curti, Luisa Giaccone, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Elisa Diral, Vladan Vucinic, Gregorio Maria Bergonzi, Maria Teresa Voso, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Elena Riva, Mattia Delleani, Angela Consagra, Francesca Ficara, Armando Santoro, Luciana Carota, Tiziana Sanavia, Cesare Rollo, Ahmad Kiwan, Jennifer VanOudenhove, Piero Fariselli, Najla H. Al Ali, David Sallman, Wolfgang Kern, Guillermo Garcia-Manero, Swapna Thota, Elizabeth A. Griffiths, Matilde Yung Follo, Carlo Finelli, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Rafael Bejar, Felicitas R. Thol, Nicolaus Kröger, Pierre Fenaux, Raphael Itzykson, Timothy Aaron Graubert, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Mrinal M. Patnaik, Eric Solary, Eric Padron, Matteo Giovanni Della Porta

Blood (2024) 144 (Supplement 1): 1003.

https://doi.org/10.1182/blood-2024-200104

Published: 2024

Journal Articles

Artificial-Intelligence, Data-Driven, Comprehensive Classification of Myeloid Neoplasms Based on Genomic, Morphological and Histological Features

Luca Lanino, Saverio D'Amico, Giulia Maggioni, Najla H. Al Ali, Yu-Hung Wang, Carmelo Gurnari, Nico Gagelmann, Jan Philipp Bewersdorf, Somedeb Ball, Paola Guglielmelli, Manja Meggendorfer, Anthony M. Hunter, Anne Sophie Kubasch, Erica Travaglino, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Cristina Astrid Tentori, Alessandro Buizza, Elisabetta Sauta, Matteo Zampini, Elena Riva, Gianluca Asti, Mattia Delleani, Francesca Ficara, Armando Santoro, Claudia Sala, Daniele Dall'Olio, Lorenzo Dall'Olio, Tariq Kewan, Ilaria Carola Casetti, Hussein Awada, Blanca Xicoy, Vladan Vucinic, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Angela Consagra, David Sallman, Wolfgang Kern, Massimo Bernardi, Patrizia Chiusolo, Lorenza Maria Borin, Maria Teresa Voso, Lisa Pleyer, Laura Palomo, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Guillermo Garcia-Manero, Sanam Loghavi, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Nicolaus Kröger, Pierre Fenaux, Michaela Fontenay, Valeria Santini, Torsten Haferlach, Ulrich Germing, Eric Padron, Marie Robin, Francesco Passamonti, Eric Solary, Alessandro M. Vannucchi, Gastone Castellani, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta

Blood (2024) 144 (Supplement 1): 1005.

https://doi.org/10.1182/blood-2024-204826

Published: 2024

Journal Articles

Granulocyte Derived Resistin Induces Classical Monocyte Repartition and Immune Suppression in CMML

Nathan J Hull, Rachel Cant, Yu-Hung Wang, Kristian Gurashi, Laura A Guest, Daniel H Wiseman, Kiran Batta

Blood (2024) 144 (Supplement 1): 880.

https://doi.org/10.1182/blood-2024-205238

Published: 2024

Journal Articles

Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion

Blood (2024) 144 (16): 1722–1731.

https://doi.org/10.1182/blood.2024023840

Published: 2024

Includes: Supplemental data

Journal Articles

Prognostic and Therapeutic Implications of TP53 expression in Chronic Myelomonocytic Leukaemia: Results of a Multicentre Study

Yu-Hung Wang, Chien-Chin Lin, Kristian Gurashi, Fabio Amaral, Chi-Yuan Yao, Joanna Storer, Luciano Nicosia, Bettina Wingelhofer, Hsin-An Hou, Andres Jerez, Wen-Chien Chou, Kiran Batta, Hwei-Fang Tien, Daniel H Wiseman

Blood (2023) 142 (Supplement 1): 3213.

https://doi.org/10.1182/blood-2023-180034

Published: 2023

Journal Articles

HMR Mutations Drive Poor Prognosis in Myelofibrosis Patients with Lower JAK2 V617F Allele Burden but Not in Those with Higher Allele Burden: Results of a Multicenter Study

Yu-Hung Wang, Carmelo Gurnari, Chao-Hung Wei, Hussein Awada, Chien-Chin Lin, Andrius Zucenka, Chi-Yuan Yao, Kristian Gurashi, Hsin-An Hou, Kiran Batta, Wen-Chien Chou, Jaroslaw P. Maciejewski, Daniel H Wiseman, Hwei-Fang Tien

Blood (2023) 142 (Supplement 1): 627.

https://doi.org/10.1182/blood-2023-179907

Published: 2023

Journal Articles

TP53 G ene a llelic State in Myelodysplastic Syndromes (MDS) with Isolated 5q Deletion

Blood (2023) 142 (Supplement 1): 1001.

https://doi.org/10.1182/blood-2023-179171

Published: 2023

Journal Articles

Validation and Retraining of the Stellae-123 Gene Expression Signature Improved Risk Stratification in Taiwanese Acute Myeloid Leukemia Patients

Yu-Hung Wang, Adrian Mosquera Orgueira, Chien-Chin Lin, Chi-Yuan Yao, Min Yen Lo, Cheng-Hong Tsai, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien

Blood (2023) 142 (Supplement 1): 1472.

https://doi.org/10.1182/blood-2023-179847

Published: 2023

Journal Articles

Integrative Analysis of Blast Phase Chronic Myelomonocytic Leukemia Reveals Distinct Transformation Phenotypes Predictive of Drug Response

Kristian Gurashi, Yu-Hung Wang, Tim C.P Somervaille, Kiran Batta, Daniel H Wiseman

Blood (2022) 140 (Supplement 1): 213–214.

https://doi.org/10.1182/blood-2022-168831

Published: 2022

Journal Articles

A Three Gene Leukemic Stem Cell Signature Score Is Robustly Prognostic in Chronic Myelomonocytic Leukemia

Yu-Hung Wang, Chi-Yuan Yao, Chien-Chin Lin, Kristian Gurashi, Fabio Amaral, Andres Jerez, Tim C.P Somervaille, Hsin-An Hou, Wen-Chien Chou, Kiran Batta, Hwei-Fang Tien, Daniel H Wiseman

Blood (2022) 140 (Supplement 1): 1104–1105.

https://doi.org/10.1182/blood-2022-165449

Published: 2022

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SRSF2 mutation-induced CHD8 exon skipping represents a novel pathogenic mediator and therapeutic dependence in chronic myelomonocytic leukemia (CMML)

Refining the prognostic hierarchy of TP53 multihit alterations and isolated deletion of chromosome 5q in myelodysplastic syndromes

Myelodysplastic/myeloproliferative overlap neoplasms: Clinicopathological features, treatment strategies, and outcomes — a UK multicentre cohort Study

Investigating the clonal and biological underpinnings of systemic mastocytosis with an associated hematological neoplasm

Choice of hypomethylating agent for newly diagnosed TP53-mutant Acute Myeloid Leukemia: A command registry study

Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS

Genomic and transcriptomic characterization of acute myeloid leukemia with CD123 overexpression

Redefining the myeloid disease continuum: Machine learning–based development and validation of an integrated multimodal classification of myeloid neoplasms

Incorporating TET2 Variant Allele Frequency Enhances Prognostication in CMML: Insights from 849 Patients across Multiple Institutions

Newly Developed Prognostic Score for Myelodysplastic Syndrome (MDS) with Isolated 5q Deletion (IPSS-del(5q))

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Artificial-Intelligence, Data-Driven, Comprehensive Classification of Myeloid Neoplasms Based on Genomic, Morphological and Histological Features

Granulocyte Derived Resistin Induces Classical Monocyte Repartition and Immune Suppression in CMML

Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion

Prognostic and Therapeutic Implications of TP53 expression in Chronic Myelomonocytic Leukaemia: Results of a Multicentre Study

HMR Mutations Drive Poor Prognosis in Myelofibrosis Patients with Lower JAK2 V617F Allele Burden but Not in Those with Higher Allele Burden: Results of a Multicenter Study

TP53 G ene a llelic State in Myelodysplastic Syndromes (MDS) with Isolated 5q Deletion

Validation and Retraining of the Stellae-123 Gene Expression Signature Improved Risk Stratification in Taiwanese Acute Myeloid Leukemia Patients

Integrative Analysis of Blast Phase Chronic Myelomonocytic Leukemia Reveals Distinct Transformation Phenotypes Predictive of Drug Response

A Three Gene Leukemic Stem Cell Signature Score Is Robustly Prognostic in Chronic Myelomonocytic Leukemia

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