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Ulrich Germing
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Journal Articles

Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion

CME Clinical Trials & Observations
Maria Julia Montoro, Laura Palomo, Claudia Haferlach, Pamela Acha, Onyee Chan, Víctor Navarro, Yasuo Kubota, Felicitas Isabel Schulz, Manja Meggendorfer, Robert Briski, Najla Al Ali, Blanca Xicoy, Félix López-Cadenas, Francesc Bosch, Teresa González, Lea Naomi Eder, Andrés Jerez, Yu-Hung Wang, Alessia Campagna, Valeria Santini, Teresa Bernal del Castillo, Esperanza Such, Hwei-Fang Tien, Nicolás Diaz Varela, Uwe Platzbecker, Detlef Haase, María Díez-Campelo, Matteo Della Porta, Guillermo Garcia-Manero, Daniel H. Wiseman, Ulrich Germing, Jaroslaw P. Maciejewski, Rami S. Komrokji, Francesc Sole, Torsten Haferlach, David Valcárcel
Journal: Blood
Blood (2024) 144 (16): 1722–1731.
https://doi.org/10.1182/blood.2024023840
Published: 2024
Includes: Supplemental data
Journal Articles

Molecular taxonomy of myelodysplastic syndromes and its clinical implications

Clinical Trials & Observations
Elsa Bernard, Robert P. Hasserjian, Peter L. Greenberg, Juan E. Arango Ossa, Maria Creignou, Heinz Tuechler, Jesus Gutierrez-Abril, Dylan Domenico, Juan S. Medina-Martinez, Max Levine, Konstantinos Liosis, Noushin Farnoud, Maria Sirenko, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Yasuhito Nannya, Olivier Kosmider, Matilde Y. Follo, Felicitas Thol, Lurdes Zamora, Ronald F. Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, José Cervera, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Eva Hellström-Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2024) 144 (15): 1617–1632.
https://doi.org/10.1182/blood.2023023727
Published: 2024
Includes: Supplemental data
Journal Articles

Molecular and clinical presentation of UBA1 -mutated myelodysplastic syndromes

Brief Report
Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E. Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Birgitta Sander, Elisa Orna, Katharina Zoldan, Lea Naomi Eder, Wolfgang R. Sperr, Renate Thalhammer, Christina Ganster, Lionel Adès, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B. Beck, Eva Hellström-Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2024) 144 (11): 1221–1229.
https://doi.org/10.1182/blood.2023023723
Published: 2024
Includes: Supplemental data
Journal Articles

Diagnosis and classification of myelodysplastic syndromes

Robert P. Hasserjian, Ulrich Germing, Luca Malcovati
Journal: Blood
Blood (2023) 142 (26): 2247–2257.
https://doi.org/10.1182/blood.2023020078
Published: 2023
Includes: Supplemental data
Journal Articles

Data-Driven Harmonization of 2022 Who and ICC Classifications of Myelodysplastic Syndromes/Neoplasms (MDS): A Study By the International Consortium for MDS (icMDS)

Luca Lanino, Somedeb Ball, Jan Philipp Bewersdorf, Monia Marchetti, Giulia Maggioni, Erica Travaglino, Najla H Al Ali, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Maria Diez-Campelo, Avani M Singh, Akriti Gupta Jain, Luis E. Aguirre, Sara M. Tinsley-Vance, Zaker I. Schwabkey, Onyee Chan, Zhuoer Xie, Andrew M. Brunner, Andrew T. Kuykendall, John M. Bennett, Rena Buckstein, Rafael Bejar, Hetty E. Carraway, Amy E. DeZern, Elizabeth A. Griffiths, Stephanie Halene, Robert Hasserjian, Jeffrey Lancet, Alan F. List, Sanam Loghavi, Olatoyosi Odenike, Eric Padron, Mrinal M. Patnaik, Gail J. Roboz, Maximilian Stahl, Mikkael A. Sekeres, David Peter Steensma, Michael R. Savona, Justin Taylor, Mina Xu, Kendra Sweet, David A Sallman, Stephen D. Nimer, Christopher S. Hourigan, Andrew H. Wei, Elisabetta Sauta, Saverio D'Amico, Gianluca Asti, Gastone Castellani, Uma M. Borate, Guillermo Sanz, Fabio Efficace, Steven D. Gore, Tae Kon Kim, Naval Daver, Guillermo Garcia-Manero, María Rozman, Alberto Orfao, Sa A. Wang, M. Kathy Foucar, Ulrich Germing, Torsten Haferlach, Phillip Scheinberg, Yasushi Miyazaki, Marcelo Iastrebner, Austin Kulasekararaj, Thomas Cluzeau, Shahram Kordasti, Arjan A. van de Loosdrecht, Lionel Ades, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta
Journal: Blood
Blood (2023) 142 (Supplement 1): 998.
https://doi.org/10.1182/blood-2023-186580
Published: 2023
Journal Articles

Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications

Elsa Bernard, Robert Hasserjian, Peter L. Greenberg, Juan E Arango Ossa, Maria Creignou, Yasuhito Nannya, Heinz Tuechler, Juan S Medina-Martínez, Max F Levine, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Olivier Kosmider, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K Elias, Detlef Haase, Maria Sirenko, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Sole, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Luca Malcovati, Mario Cazzola, Seishi Ogawa, Eva Hellstrom Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 997.
https://doi.org/10.1182/blood-2023-186863
Published: 2023
Journal Articles

TP53 G ene a llelic State in Myelodysplastic Syndromes (MDS) with Isolated 5q Deletion

Julia Montoro, Laura Palomo, Claudia Haferlach, Pamela Acha, Onyee Chan, Victor Navarro Garces, Yasuo Kubota, Felicitas Schulz, Manja Meggendorfer, Robert Briski, Najla H Al Ali, Blanca Xicoy, Felix Lopez, Pablo Vidal, Francesc Bosch, Teresa González, Lea Naomi Eder, Andres Jerez, Hwei-Fang Tien, Valeria Santini, Teresa Bernal Del Castillo, Esperanza Such, Yu-Hung Wang, Anne Sophie Kubasch, Uwe Platzbecker, Detlef Haase, Maria Diez-Campelo, Matteo Giovanni Della Porta, Guillermo Garcia-Manero, Daniel H Wiseman, Ulrich Germing, Jaroslaw P. Maciejewski, Rami S. Komrokji, Francesc Sole, Torsten Haferlach, David Valcarcel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1001.
https://doi.org/10.1182/blood-2023-179171
Published: 2023
Journal Articles

Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes

David Rombaut, Tobias Tekath, Sarah Sandmann, Simon Crouch, Aniek O. de Graaf, Olivier Kosmider, Magnus Tobiasson, Andreas Lennartsson, Bert A. Van der Reijden, Sophie Park, Maud D'Aveni, Bohrane Slama, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Arjan A. van de Loosdrecht, Saskia MC Langemeijer, Argiris S. Symeonidis, Jaroslav Čermák, Claude Preudhomme, Aleksandar Savic, Ulrich Germing, Reinhard Stauder, David T. Bowen, Corine J. Van Marrewijk, Elsa Bernard, Alexandra Smith, Daniel Painter, Theo J.M. de Witte, Eva Hellstrom Lindberg, Julian Varghese, Martin Dugas, Joost H.A. Martens, Luca Malcovati, Joop H. Jansen, Michaela Fontenay
Journal: Blood
Blood (2023) 142 (Supplement 1): 4587.
https://doi.org/10.1182/blood-2023-180071
Published: 2023
Journal Articles

Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Myelodysplastic Syndromes (MDS)

Cristina Astrid Tentori, Caterina Gregorio, Marie Robin, Nico Gagelmann, Carmelo Gurnari, Somedeb Ball, Juan Carlos Caballero Berrocal, Luca Lanino, Saverio D'Amico, Marta Spreafico, Giulia Maggioni, Erica Travaglino, Elisabetta Sauta, Manja Meggendorfer, Lin-Pierre Zhao, Massimo Bernardi, Carmen Di Grazia, Luca Vago, Giulia Rivoli, Lorenza Maria Borin, Patrizia Chiusolo, Luisa Giaccone, Maria Teresa Voso, Jan Philipp Bewersdorf, Olivier Nibourel, Marina Díaz-Beyá, Andres Jerez, Francisca Maria Hernandez, Kyra Velázquez Kennedy, Blanca Xicoy, Marta Ubezio, Alessia Campagna, Antonio Russo, Gabriele Todisco, Daniele Mannina, Stefania Bramanti, Matteo Zampini, Elena Riva, Marilena Bicchieri, Gianluca Asti, Filippo Viviani, Alessandro Buizza, Benedetta Tinterri, Andrea Bacigalupo, Alessandro Rambaldi, Francesco Passamonti, Fabio Ciceri, Victor Savevski, Armando Santoro, Najla H Al Ali, David A Sallman, Francesc Sole, Guillermo Garcia-Manero, Ulrich Germing, Shahram Kordasti, Valeria Santini, Guillermo Sanz, Wolfgang Kern, Anne Sophie Kubasch, Uwe Platzbecker, Maria Diez-Campelo, Jaroslaw P. Maciejewski, Lionel Ades, Pierre Fenaux, Torsten Haferlach, Amer M. Zeidan, Gastone Castellani, Rami S. Komrokji, Francesca Ieva, Matteo Giovanni Della Porta
Journal: Blood
Blood (2023) 142 (Supplement 1): 197.
https://doi.org/10.1182/blood-2023-182194
Published: 2023
Journal Articles

Molecular Classification of Chronic Myelomonocytic Leukemia: Results of the Analysis of an International Cohort of 2,471 Patients

Luca Lanino, Anthony M. Hunter, Claudia Sala, Daniele Dall'Olio, Lorenzo Dall'Olio, Lisa Pleyer, Blanca Xicoy, Manja Meggendorfer, Elisabetta Sauta, Erica Travaglino, Marie Robin, Laura Palomo, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Giulia Rivoli, Massimo Bernardi, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Filippo Viviani, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Armando Santoro, Wolfgang Kern, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Angela Consagra, Najla H Al Ali, David A Sallman, Pierre Fenaux, Raphael Itzykson, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Eric Solary, Eric Padron, Matteo Giovanni Della Porta
Journal: Blood
Blood (2023) 142 (Supplement 1): 3244.
https://doi.org/10.1182/blood-2023-184536
Published: 2023
Journal Articles

The Genomic Landscape and Its Clinical Implication in NPM1 -Mutated AML Patients: A Study within the AMLSG 09-09 Clinical Trial

Sibylle Cocciardi, Nina Weiß, Maral Saadati, Sabrina Skambraks, Daniela Weber, Isabelle Schneider, Annika Meid, Sophia Aicher, Kathrin Bengesser-Kuhn, Andrea Corbacioglu, Verena I. Gaidzik, Frauke Theis, Walter Fiedler, Michael Kühn, Ulrich Germing, Karin T. Mayer, Michael Lübbert, Felicitas Thol, Michael Heuser, Arnold Ganser, Lars Bullinger, Axel Benner, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2023) 142 (Supplement 1): 4311.
https://doi.org/10.1182/blood-2023-185566
Published: 2023
Journal Articles

Chronic Myelomonocytic Leukemia (CMML) with AML Typical Mutations ( NPM1, FLT3 or CEBPA ) Identify a High-Risk CMML Group Independent of Molecular-Cpss

Sandra Castaño-Díez, Ines Zugasti, Xavier Calvo, Felicitas Schulz, Alejandro Avendaño Pita, Elvira Mora, Jose Francisco Falantes, Gemma Azaceta, Mariam Ibáñez, Tzu Chen, Cristina Notario, Neus Amer Salas, Mònica López-Guerra, Carlos Jimenez-Vicente, Daniel Esteban, Francesca Guijarro, José Ramón Álamo Moreno, Albert Cortés-Bullich, Daniel Munárriz, Víctor Torrecillas-Mayayo, Ana Triguero, Natalia Tovar, Alexandra Martínez-Roca, Beatriz Merchán Muñoz, Esther Carcelero, Ulrich Germing, Beate Betz, María Rozman, Leonor Arenillas, Lurdes Zamora, Maria Diez-Campelo, Blanca Xicoy, Jordi Esteve, Marina Díaz-Beyá
Journal: Blood
Blood (2023) 142 (Supplement 1): 3231.
https://doi.org/10.1182/blood-2023-173311
Published: 2023
Journal Articles

UBA1 Mutations Identify a Rare but Distinct Subtype of Myelodysplastic Syndromes

Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Andrea Pellagatti, Harold K Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Sole, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B Beck, Eva Hellstrom Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1862.
https://doi.org/10.1182/blood-2023-182949
Published: 2023
Journal Articles

The Significance of Variant Allele Frequency in SF3B1 Mutated Myelodysplastic Neoplasms/Syndromes

Curtis A. Lachowiez, Georgios Asimomitis, Elsa Bernard, Ivory Tang, Maria Creignou, Ulrich Germing, Norbert Gattermann, Luca Malcovati, Mario Cazzola, Eva Hellstrom Lindberg, Elli Papaemmanuil, Sanam Loghavi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1870.
https://doi.org/10.1182/blood-2023-179899
Published: 2023
Journal Articles

Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes

Clinical Trials & Observations
Amer M. Zeidan, Uwe Platzbecker, Jan Philipp Bewersdorf, Maximilian Stahl, Lionel Adès, Uma Borate, David Bowen, Rena Buckstein, Andrew Brunner, Hetty E. Carraway, Naval Daver, Maria Díez-Campelo, Theo de Witte, Amy E. DeZern, Fabio Efficace, Guillermo Garcia-Manero, Jacqueline S. Garcia, Ulrich Germing, Aristoteles Giagounidis, Elizabeth A. Griffiths, Robert P. Hasserjian, Eva Hellström-Lindberg, Marcelo Iastrebner, Rami Komrokji, Austin G. Kulasekararaj, Luca Malcovati, Yasushi Miyazaki, Olatoyosi Odenike, Valeria Santini, Guillermo Sanz, Phillip Scheinberg, Reinhard Stauder, Arjan A. van de Loosdrecht, Andrew H. Wei, Mikkael A. Sekeres, Pierre Fenaux
Journal: Blood
Blood (2023) 141 (17): 2047–2061.
https://doi.org/10.1182/blood.2022018604
Published: 2023
Includes: Supplemental data
Journal Articles

Comparison of Cytomorphology and Histopathology in Myelodysplastic Syndromes (MDS)

Kathrin Nachtkamp, Corinna Strupp, Rosa Faoro, Norbert Gattermann, Ulrich Germing, Stephan E Baldus
Journal: Blood
Blood (2022) 140 (Supplement 1): 12345–12346.
https://doi.org/10.1182/blood-2022-166172
Published: 2022
Journal Articles

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry: A Report on 197 Cases

Inga Mandac Smoljanovic, Adele Taylor, Pierre Fenaux, Agnès Guerci-Bresler, Raphael Itzykson, Argiris Symeonidis, Ioannis Kotsianidis, Moshe Mittelman, Guillermo Sanz, Dominic J. Culligan, Jaroslav Cermak, Reinhard Stauder, Eva Hellström-Lindberg, Luca Malcovati, Saskia M.C. Langemeijer, Ulrich Germing, Krzysztof Madry, Howard S. Oster, Alexandra Smith, Corine van Marrewijk, Theo M de Witte, David Bowen
Journal: Blood
Blood (2022) 140 (Supplement 1): 9802–9803.
https://doi.org/10.1182/blood-2022-167716
Published: 2022
Journal Articles

Real-World Validation of Molecular International Prognostic Scoring System (IPSS-M) for Myelodysplastic Syndromes

Elisabetta Sauta, Marie Robin, Matteo Bersanelli, Erica Travaglino, Manja Meggendorfer, Lin-Pierre Zhao, Juan Carlos Caballero Berrocal, Giulia Maggioni, Cristina Astrid Tentori, Massimo Bernardi, Carmen Di Grazia, Luca Vago, Giulia Rivoli, Lorenza Borin, Saverio D'Amico, Marta Ubezio, Alessia Campagna, Antonio Russo, Daniele Mannina, Luca Lanino, Patrizia Chiusolo, Luisa Giaccone, Maria Teresa Voso, Marta Riva, Esther Natalie Oliva, Matteo Zampini, Elena Riva, Olivier Nibourel, Claudia Sala, Marilena Bicchieri, Niccolò Bolli, Alessandro Rambaldi, Francesco Passamonti, Victor Savevski, Armando Santoro, Ulrich Germing, Shahram Kordasti, Valeria Santini, Maria Diez-Campelo, Guillermo Sanz, Francesc Solé, Wolfgang Kern, Uwe Platzbecker, Lionel Ades, Pierre Fenaux, Torsten Haferlach, Castellani Gastone, Matteo G. Della Porta
Journal: Blood
Blood (2022) 140 (Supplement 1): 1121–1124.
https://doi.org/10.1182/blood-2022-163634
Published: 2022
Journal Articles

Imetelstat Achieved Prolonged, Continuous Transfusion Independence (TI) in Patients with Heavily Transfused Non-Del(5q) Lower-Risk Myelodysplastic Syndrome (LR-MDS) Relapsed/Refractory (R/R) to Erythropoiesis Stimulating Agents (ESAs) within the IMerge Phase 2 Study

Uwe Platzbecker, Rami S. Komrokji, Pierre Fenaux, Amer M. Zeidan, Mikkael A. Sekeres, Michael Robert Savona, Yazan F. Madanat, Valeria Santini, Koen Van Eygen, Azra Raza, Ulrich Germing, Tymara Berry, Souria Dougherty, Sheetal Shah, Libo Sun, Fei Huang, Faye Feller, Ying Wan, Annat Ikin, Laurie Sherman
Journal: Blood
Blood (2022) 140 (Supplement 1): 1106–1108.
https://doi.org/10.1182/blood-2022-169050
Published: 2022
Journal Articles

Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories

Michael Pfeilstocker, Heinz Tuechler, Lionel Ades, Jaroslav Cermak, Fatiha Chermat, Matteo G. Della Porta, Pierre Fenaux, Guillermo Garcia-Manero, Ulrich Germing, Detlef Haase, Andrea Kuendgen, Michael Luebbert, Silvia Maria Meira Magalhaes, Luca Malcovati, Yasushi Miyazaki, Guillermo Sanz, Valeria Santini, Mikkael A. Sekeres, Matthew J Walter, Peter Valent, Peter L Greenberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 6976–6978.
https://doi.org/10.1182/blood-2022-158671
Published: 2022