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Journal Articles

Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS

Blood (2025) 146 (Supplement 1): 115.

https://doi.org/10.1182/blood-2025-115

Published: 2025

Journal Articles

Therapy-induced senescence reprograms non-M3 AML into a drug-exploitable APL-like state

Martin Schönlein, Wencke Walter, Paulina Richter-Pechanska, Katharina Barbara Rösel, Diego Gilioli, Zhiting Shao, Jana Ihlow, Karsten Spiekermann, Katharina S. Götze, Soyoung Lee, Yong Yu, Torsten Haferlach, Hugues De Thé, Raffaella Di Micco, Clemens Schmitt

Blood (2025) 146 (Supplement 1): 3244.

https://doi.org/10.1182/blood-2025-3244

Published: 2025

Journal Articles

MPN with multiple driver clones show distinct patterns of therapy response and progression - “MPN double driver”

Blood (2025) 146 (Supplement 1): 1021.

https://doi.org/10.1182/blood-2025-1021

Published: 2025

Journal Articles

Determining the origin of TP53 mutations in patients with mature B-cell neoplasms is essential to distinguish lymphoma-related mutations from those due to clonal hematopoiesis, helping to guide treatment decisions

Veronika Ecker, Wencke Walter, Martha-Lena Mueller, Nicola Goetz, Christiane Eder, Manja Meggendorfer, Sandra Huber, Jana Wobst, Wolfgang Kern, Gregor Hoermann

Blood (2025) 146 (Supplement 1): 5389.

https://doi.org/10.1182/blood-2025-5389

Published: 2025

Journal Articles

Long-read single-cell isoform sequencing for cell type-specific detection of genomic rearrangement-dependent and -independent fusion transcripts

Wencke Walter, Wolfgang Kern, Anna Stengel

Blood (2025) 146 (Supplement 1): 6117.

https://doi.org/10.1182/blood-2025-6117

Published: 2025

Journal Articles

CLL with t(11;14)(q13;q32) or t(14:18)(q32:q21) – is this CLL or lymphoma?

Alessandro Baldi, Wencke Walter, Anna Stengel, Heiko Mueller, Manja Meggendorfer, Isolde Summerer, Wolfgang Kern, Veronika Ecker

Blood (2025) 146 (Supplement 1): 2114.

https://doi.org/10.1182/blood-2025-2114

Published: 2025

Journal Articles

The rearrangement partner and the presence of MYC mutations determines outcome of patients with MYC and BCL6 rearrangements

Anna Stengel, Miriam Lenk, Wolfgang Kern, Wencke Walter

Blood (2025) 146 (Supplement 1): 1749.

https://doi.org/10.1182/blood-2025-1749

Published: 2025

Journal Articles

MDS without clonal marker: When depth outperforms breadth

Sandra Huber, Wencke Walter, Marietta Truger, Stephan Hutter, Heiko Mueller, Torsten Haferlach, Manja Meggendorfer

Blood (2025) 146 (Supplement 1): 2071.

https://doi.org/10.1182/blood-2025-2071

Published: 2025

Journal Articles

EZH2 molecular alterations drive micromegakaryocyte expansion in MDS defining a specific high-risk group

Blood (2025) 146 (Supplement 1): 2084.

https://doi.org/10.1182/blood-2025-2084

Published: 2025

Journal Articles

Bi-allelic TET2 alterations are frequently found in NPM1 mutated AML and constitute a distinct subgroup with unfavorable prognosis

Wencke Walter, Sarah Keppler, Veronika Ecker, Wolfgang Kern, Torsten Haferlach, Anna Stengel

Blood (2025) 146 (Supplement 1): 339.

https://doi.org/10.1182/blood-2025-339

Published: 2025

Journal Articles

Determining telomere content and genomics of myeloid neoplasia by whole-genome sequencing

Blood blood.2025028644.

https://doi.org/10.1182/blood.2025028644

Published: 2025

Includes: Supplemental data

Journal Articles

Integrateall, a Machine Learning Pipeline for Multi-Level Data Extraction from RNA-Seq Profiles Unravels Novel Drivers and Systematic Subtype Classification in B-Cell Precursor ALL

Nadine Wolgast, Thomas Beder, Mayukh Mondal, Wencke Walter, Stephan Hutter, Sonja Bendig, Jan Kässens, Björn-Thore Hansen, Katharina Iben, Barz Malwine, Martin Neumann, Nicola Goekbuget, Claudia Haferlach, Monika Brüggemann, Claudia D Baldus, Alina M. Hartmann, Lorenz Bastian

Blood (2024) 144 (Supplement 1): 4213.

https://doi.org/10.1182/blood-2024-199557

Published: 2024

Journal Articles

Subtype Classification of BCP-ALL Dic(9;20)

Wencke Walter, Anna Stengel, Manja Meggendorfer, Torsten Haferlach, Wolfgang Kern, Claudia Haferlach

Blood (2024) 144 (Supplement 1): 5914.

https://doi.org/10.1182/blood-2024-204542

Published: 2024

Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Blood (2024) 144 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2024-209923

Published: 2024

Journal Articles

Single-Cell Transcriptomics of Bone Marrow Mesenchymal Stromal Cells Identifies Altered CLCF1 Signaling in DNMT3A -Mutated Clonal Hematopoiesis

Anna Navarro Figueredo, Daniele Scarcella, Michele C Buck, Maximilian Buser, Jennifer Rivière, Michael Sterr, Wencke Walter, Priyansh Srivastava, Judith S. Hecker, Ana Conesa, Mark van der Garde, Carsten Marr, Katharina S. Götze

Blood (2024) 144 (Supplement 1): 2676.

https://doi.org/10.1182/blood-2024-210254

Published: 2024

Journal Articles

C/EBP Family Member Gene Fusions and Cooperating Genomic Events Define Two Distinct Molecular Sub-Groups in Adult B Precursor ALL

Blood (2024) 144 (Supplement 1): 1458.

https://doi.org/10.1182/blood-2024-211088

Published: 2024

Journal Articles

Phenotypic and Genetic Heterogeneity of NPM1 Mutated AML at Diagnosis and during Course of Disease

Veronika Ecker, Sandra Huber, Wencke Walter, Stephan Hutter, Martha-Lena Mueller, Manja Meggendorfer, Constance Regina Baer, Claudia Haferlach, Torsten Haferlach, Wolfgang Kern

Blood (2024) 144 (Supplement 1): 6118.

https://doi.org/10.1182/blood-2024-209675

Published: 2024

Journal Articles

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A. Betram, Richard Moriggl, Thomas Rülicke, Charles G. Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt

Blood (2024) 143 (24): 2474–2489.

https://doi.org/10.1182/blood.2023022655

Published: 2024

Includes: Supplemental data

Journal Articles

Developmental trajectories and cooperating genomic events define molecular subtypes of BCR :: ABL1 -positive ALL

Blood (2024) 143 (14): 1391–1398.

https://doi.org/10.1182/blood.2023021752

Published: 2024

Includes: Supplemental data

Journal Articles

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Francis Baumgartner, Constance Baer, Stefanos Bamopoulos, Edward Ayoub, Marietta Truger, Manja Meggendorfer, Miriam Lenk, Gregor Hoermann, Stephan Hutter, Heiko Müller, Wencke Walter, Martha-Lena Müller, Niroshan Nadarajah, Piers Blombery, Ulrich Keller, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach

Blood (2024) 143 (12): 1139–1156.

https://doi.org/10.1182/blood.2023021199

Published: 2024

Includes: Supplemental data

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Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS

Therapy-induced senescence reprograms non-M3 AML into a drug-exploitable APL-like state

MPN with multiple driver clones show distinct patterns of therapy response and progression - “MPN double driver”

Determining the origin of TP53 mutations in patients with mature B-cell neoplasms is essential to distinguish lymphoma-related mutations from those due to clonal hematopoiesis, helping to guide treatment decisions

Long-read single-cell isoform sequencing for cell type-specific detection of genomic rearrangement-dependent and -independent fusion transcripts

CLL with t(11;14)(q13;q32) or t(14:18)(q32:q21) – is this CLL or lymphoma?

The rearrangement partner and the presence of MYC mutations determines outcome of patients with MYC and BCL6 rearrangements

MDS without clonal marker: When depth outperforms breadth

EZH2 molecular alterations drive micromegakaryocyte expansion in MDS defining a specific high-risk group

Bi-allelic TET2 alterations are frequently found in NPM1 mutated AML and constitute a distinct subgroup with unfavorable prognosis

Determining telomere content and genomics of myeloid neoplasia by whole-genome sequencing

Integrateall, a Machine Learning Pipeline for Multi-Level Data Extraction from RNA-Seq Profiles Unravels Novel Drivers and Systematic Subtype Classification in B-Cell Precursor ALL

Subtype Classification of BCP-ALL Dic(9;20)

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Single-Cell Transcriptomics of Bone Marrow Mesenchymal Stromal Cells Identifies Altered CLCF1 Signaling in DNMT3A -Mutated Clonal Hematopoiesis

C/EBP Family Member Gene Fusions and Cooperating Genomic Events Define Two Distinct Molecular Sub-Groups in Adult B Precursor ALL

Phenotypic and Genetic Heterogeneity of NPM1 Mutated AML at Diagnosis and during Course of Disease

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Developmental trajectories and cooperating genomic events define molecular subtypes of BCR :: ABL1 -positive ALL

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

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