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Walter Fiedler
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Journal Articles

Developmental trajectories and cooperating genomic events define molecular subtypes of BCR :: ABL1 -positive ALL

Clinical Trials & Observations Brief Report
Lorenz Bastian, Thomas Beder, Malwine J. Barz, Sonja Bendig, Lorenz Bartsch, Wencke Walter, Nadine Wolgast, Björn Brändl, Christian Rohrandt, Björn-Thore Hansen, Alina M. Hartmann, Katharina Iben, Dennis Das Gupta, Miriam Denker, Johannes Zimmermann, Michael Wittig, Guranda Chitadze, Martin Neumann, Folker Schneller, Walter Fiedler, Björn Steffen, Matthias Stelljes, Christoph Faul, Stefan Schwartz, Franz-Josef Müller, Gunnar Cario, Lana Harder, Claudia Haferlach, Heike Pfeifer, Nicola Gökbuget, Monika Brüggemann, Claudia D. Baldus
Journal: Blood
Blood (2024) 143 (14): 1391–1398.
https://doi.org/10.1182/blood.2023021752
Published: 2024
Includes: Supplemental data
Journal Articles

Molecular Subtypes in BCR::ABL1 -Positive ALL Are Defined By Cellular Origins and Cooperating Genomic Events

Lorenz Bastian, Thomas Beder, Malwine Barz, Sonja Bendig, Lorenz Bartsch, Wencke Walter, Nadine Wolgast, Björn Brändl, Christian Rohrandt, Björn-Thore Hansen, Alina M. Hartmann, Katharina Iben, Miriam Bultmann, Johannes Zimmermann, Michael Wittig, Guranda Chitadze, Martin Neumann, Folker Schneller, Walter Fiedler, Björn Steffen, Matthias Stelljes, Christoph Faul, Stefan Schwartz, Franz-Josef Müller, Gunnar Cario, Lana Harder, Claudia Haferlach, Heike Pfeifer, Nicola Goekbuget, Monika Brüggemann, Claudia D Baldus
Journal: Blood
Blood (2023) 142 (Supplement 1): 843.
https://doi.org/10.1182/blood-2023-187315
Published: 2023
Journal Articles

The Genomic Landscape and Its Clinical Implication in NPM1 -Mutated AML Patients: A Study within the AMLSG 09-09 Clinical Trial

Sibylle Cocciardi, Nina Weiß, Maral Saadati, Sabrina Skambraks, Daniela Weber, Isabelle Schneider, Annika Meid, Sophia Aicher, Kathrin Bengesser-Kuhn, Andrea Corbacioglu, Verena I. Gaidzik, Frauke Theis, Walter Fiedler, Michael Kühn, Ulrich Germing, Karin T. Mayer, Michael Lübbert, Felicitas Thol, Michael Heuser, Arnold Ganser, Lars Bullinger, Axel Benner, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2023) 142 (Supplement 1): 4311.
https://doi.org/10.1182/blood-2023-185566
Published: 2023
Journal Articles

Phase Ib/II Study (NCT02488408 / BGBC003) of Bemcentinib Monotherapy or in Combination with Cytarabine or Decitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS): FINAL Results

Sonja Loges, Michael Heuser, Jolanta Chromik, Grerk Sutamtewagul, Silke Kapp-Schwoerer, Monica Crugnola, Nicola Di Renzo, Roberto Massimo Lemoli, Daniele Giovanni Mattei, Isabel Ben Batalla, Jonas Waizenegger, Melanie Janning, Lisa-Marie Rieckmann, Charles Imbusch, Niklas Beumer, David Micklam, Claudia Gorcea-Carson, Cristina Oliva, Walter Fiedler, Yesid Alvarado-Valero, Nigel McCracken, Bjorn T. Gjertsen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4287.
https://doi.org/10.1182/blood-2023-181833
Published: 2023
Journal Articles

Myelodysplasia-Related Gene Mutations for NGS-Based MRD Assessment in Acute Myeloid Leukemia

Maximilian Bader, Arba Mahmuti, Jannika Leßmann, Henri C Hupe, Razif Gabdoulline, Martin Wichmann, Letizia Venturini, Michael Stadler, Wolfram Puppe, Walter Fiedler, Jürgen Krauter, Arne Trummer, Bernd Hertenstein, Matthias Eder, Arnold Ganser, Felicitas Thol, Michael Heuser, Rabea Mecklenbrauck
Journal: Blood
Blood (2023) 142 (Supplement 1): 2944.
https://doi.org/10.1182/blood-2023-181637
Published: 2023
Journal Articles

CNS Irradiation in Adult De Novo B-Precursor ALL / Lbl: Results of the Randomized GMALL T rial 08/2013 Indicate Potential Antileukemic Efficacy

Nicola Goekbuget, Björn Steffen, Kathrin Nachtkamp, Boris Böll, Veit L. Buecklein, Christoph Faul, Jens Panse, Christoph Röllig, Folker Schneller, Bernd Spriewald, Matthias Stelljes, Max S. Topp, Andreas Viardot, Vladan Vucinic, Knut Wendelin, Monika Brüggemann, Monika Szczepanowski, Stefan Schwartz, Thomas Burmeister, Axel Benner, Nicholas Schreck, Lena Reiser, Hubert Serve, Walter Fiedler
Journal: Blood
Blood (2023) 142 (Supplement 1): 828.
https://doi.org/10.1182/blood-2023-179442
Published: 2023
Journal Articles

Prognostic Impact of Clonality of Myelodysplasia-Related Gene Mutations in AML

Rabea Mecklenbrauck, Nora Borchert, Piroska Klement, Carolin Funke, Maximilian Brandes, Louisa-Kristin Dallmann, Walter Fiedler, Jürgen Krauter, Arne Trummer, Bernd Hertenstein, Verena I. Gaidzik, Konstanze Döhner, Hartmut Döhner, Arnold Ganser, Felicitas Thol, Michael Heuser
Journal: Blood
Blood (2023) 142 (Supplement 1): 817.
https://doi.org/10.1182/blood-2023-179412
Published: 2023
Journal Articles

Updated Results from a Phase I Dose Escalation Study of the Rapidly-Switchable Universal CAR-T Therapy UniCAR-T-CD123 in Relapsed/Refractory AML

Martin Wermke, Stephan Metzelder, Sabrina Kraus, Elisa Sala, Vladan Vucinic, Walter Fiedler, Katrin Wetzko, Jonas Schäfer, Maria-Elisabeth Goebeler, Jan Koedam, Kristin Franke, Matti Vänskä, Armin Ehninger, Marc Cartellieri, Gerhard Ehninger, Tapan Maniar
Journal: Blood
Blood (2023) 142 (Supplement 1): 3465.
https://doi.org/10.1182/blood-2023-177867
Published: 2023
Journal Articles

Loss of SMARCA4 Leads to an Impaired Hematopoiesis in Mice

Franziska Modemann, Leoni Ramke, Erkin Erdal, Melanie Schoof, Carolin Göbel, Sina Neyazi, Carsten Bokemeyer, Jasmin Wellbrock, Ulrich Schüller, Walter Fiedler
Journal: Blood
Blood (2023) 142 (Supplement 1): 1377.
https://doi.org/10.1182/blood-2023-178137
Published: 2023
Journal Articles

AML Treatment By the AXL Inhibitor Bemcentinib in Combination with Cytarabine Shows Clinical Efficacy Related to TNFα and Cytotoxic Immune Cells: A Single-Cell Translational Study from the BGBC003 Trial

Niklas Beumer, Jonas S. Waizenegger, Michael Heuser, Jörg Chromik, Grerk Sutamtewagul, Silke Kapp-Schwoerer, Monica Crugnola, Nicola Di Renzo, Roberto M. Lemoli, Daniele G. Mattei, Walter Fiedler, Yesid Alvarado-Valero, David Micklem, Linn H. Nilsson, Noelly Madeleine, Nigel McCracken, Cristina Oliva, Claudia Gorcea-Carson, Lisa-Marie Rieckmann, Jenny Krause, Victoria Gensch, Isabel Ben Batalla, Melanie Janning, Nicola Gagliani, Benedikt Brors, Charles D. Imbusch, Bjorn T. Gjertsen, Sonja Loges
Journal: Blood
Blood (2023) 142 (Supplement 1): 1540.
https://doi.org/10.1182/blood-2023-185499
Published: 2023
Journal Articles

Venetoclax and Blinatumomab for Adult Patients with Relapsed/Refractory or MRD Positive Ph-Negative B-Precursor ALL: First Results of the GMALL-Bliven Trial

Lars Fransecky, Walter Fiedler, Christoph Röllig, Tim Sauer, Simon Raffel, Winfried Alsdorf, Lisa Heberling, Kumaran Nagarajan, Britta Steer, Philipp Nakov, Björn Steffen, Dorothee Deckbar, Sonja Bendig, Lorenz Bastian, Martin Neumann, Monika Brueggemann, Nicola Goekbuget, Claudia D Baldus
Journal: Blood
Blood (2023) 142 (Supplement 1): 1502.
https://doi.org/10.1182/blood-2023-173937
Published: 2023
Journal Articles

Long-term follow-up of VIALE-C in patients with untreated AML ineligible for intensive chemotherapy

Clinical Trials & Observations
Andrew H. Wei, Panayiotis Panayiotidis, Pau Montesinos, Kamel Laribi, Vladimir Ivanov, Inho Kim, Jan Novak, Rebecca Champion, Walter Fiedler, Maria Pagoni, Julie Bergeron, Stephen B. Ting, Jing-Zhou Hou, Achilles Anagnostopoulos, Andrew McDonald, Vidhya Murthy, Takahiro Yamauchi, Jianxiang Wang, Qi Jiang, Yan Sun, Brenda Chyla, Wellington Mendes, Courtney D. DiNardo
Journal: Blood
Blood (2022) 140 (25): 2754–2756.
https://doi.org/10.1182/blood.2022016963
Published: 2022
Includes: Supplemental data
Journal Articles

Gemtuzumab Ozogamicin Plus Intensive Chemotherapy for Patients with NPM1 -Mutated Acute Myeloid Leukemia

Hartmut Döhner, Daniela Weber, Julia Krzykalla, Walter Fiedler, Michael W.M. Kühn, Thomas Schroeder, Karin Mayer, Michael Lübbert, Mohammad Wattad, Katharina Götze, Lars Fransecky, Elisabeth Koller, Gerald Wulf, Jan Schleicher, Mark Ringhoffer, Richard Greil, Bernd Hertenstein, Jürgen Krauter, Uwe M. Martens, David Nachbaur, Maisun Abu Samra, Sigrid Machherndl-Spandl, Nadezda Basara, Claudia Leis, Anika Schrade, Silke Kapp-Schwoerer, Lars Bullinger, Felicitas R. Thol, Michael Heuser, Peter Paschka, Verena I. Gaidzik, Maral Saadati, Axel Benner, Richard F. Schlenk, Konstanze Döhner, Arnold Ganser
Journal: Blood
Blood (2022) 140 (Supplement 1): 2010–2013.
https://doi.org/10.1182/blood-2022-166084
Published: 2022
Journal Articles

Prognostic Impact of Clonal Hierarchy of Myelodysplasia-Related Gene Mutations in AML Patients

Rabea Mecklenbrauck, Nora Borchert, Carolin Funke, Maximilian Brandes, Louisa-Kristin Dallmann, Piroska Klement, Walter Fiedler, Jürgen Krauter, Arne Trummer, Bernd Hertenstein, Andreas Voss, Michael Lübbert, Verena I. Gaidzik, Konstanze Döhner, Hartmut Döhner, Arnold Ganser, Felicitas R. Thol, Michael Heuser
Journal: Blood
Blood (2022) 140 (Supplement 1): 6254–6255.
https://doi.org/10.1182/blood-2022-162725
Published: 2022
Journal Articles

Phase 1 Dose Escalation Study of the Rapidly Switchable Universal CAR-T Therapy Unicar-T-CD123 in Relapsed/Refractory AML

Gerhard Ehninger, Sabrina Kraus, Elisa Sala, Stephan K Metzelder, Vladan Vucinic, Walter Fiedler, Maria-Elisabeth Goebeler, Jan Moritz Middeke, Malte von Bonin, Carla Kreissig, Jan Koedam, Marc Cartellieri, Armin Ehninger, Martin Wermke, Jonas A. Schäfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 2367–2368.
https://doi.org/10.1182/blood-2022-168877
Published: 2022
Journal Articles

Long-Term Follow-up of the Phase 3 Viale-a Clinical Trial of Venetoclax Plus Azacitidine for Patients with Untreated Acute Myeloid Leukemia Ineligible for Intensive Chemotherapy

Keith W. Pratz, Brian A. Jonas, Vinod A. Pullarkat, Michael J. Thirman, Jacqueline S. Garcia, Walter Fiedler, Kazuhito Yamamoto, Jianxiang Wang, Sung-Soo Yoon, Ofir Wolach, Jun-Ho Jang, Su-Peng Yeh, Grace Ku, Ying Zhou, Brenda Chyla, Jalaja Potluri, Courtney D. DiNardo
Journal: Blood
Blood (2022) 140 (Supplement 1): 529–531.
https://doi.org/10.1182/blood-2022-158518
Published: 2022
Journal Articles

Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 281 T-ALL / T-Lbl Patients: Excellent Outcome of Standard Risk Thymic T-ALL

Nicola Goekbuget, Walter Fiedler, Nael Alakel, Max S. Topp, Maher Hanoun, Björn Steffen, Ralph Wäsch, Andreas Viardot, Kathrin Nachtkamp, Matthias Stelljes, Hendrik Poeck, Vladan Vucinic, Boris Böll, Joachim Beck, Lars Fransecky, Knut Wendelin, Folker Schneller, Christoph Faul, Veit L Buecklein, Lena Reiser, Monika Brüggemann, Hubert Serve, Stefan Schwartz
Journal: Blood
Blood (2022) 140 (Supplement 1): 115–117.
https://doi.org/10.1182/blood-2022-158381
Published: 2022
Journal Articles

Safety and Efficacy of Cusatuzumab in Combination with Venetoclax and Azacitidine (CVA) in Patients with Previously Untreated Acute Myeloid Leukemia (AML) Who Are Not Eligible for Intensive Chemotherapy; An Open-Label, Multicenter, Phase 1b Study

Gail J. Roboz, Thomas Pabst, Ahmed Aribi, Joseph M. Brandwein, Hartmut Döhner, Walter Fiedler, Domenica Gandini, Michelle Geddes, Jing-Zhou Hou, Angela J. Howes, Anna Hultberg, Eric Huselton, Julie Jacobs, Colleen Kane, Ewa Lech-Marańda, Marieke Louwers, Kerri Nottage, Uwe Platzbecker, Raajit Rampal, Mariya Salman, Priya Shah, Don Stevens, Monic Stuart, Marion Subklewe, Anne Sumbul, Eunice S. Wang, Agnieszka Wierzbowska, Bin Yao, Karen Yee, Hagop Kantarjian, Gautam Borthakur
Journal: Blood
Blood (2021) 138 (Supplement 1): 369.
https://doi.org/10.1182/blood-2021-150371
Published: 2021
Journal Articles

A Comparative Outcome Analysis of COVID-19 and Influenza Infection in Patients with Hematological Malignancies

Susanne Ghandili, Christian Niederwieser, Katja Weisel, Carsten Bokemeyer, Walter Fiedler, Franziska Modemann
Journal: Blood
Blood (2021) 138 (Supplement 1): 2286.
https://doi.org/10.1182/blood-2021-147438
Published: 2021
Journal Articles

First Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 705 Adults with Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma (ALL/LBL)

Nicola Goekbuget, Matthias Stelljes, Andreas Viardot, Kathrin Nachtkamp, Björn Steffen, Folker Schneller, Nael Alakel, Max Topp, Boris Böll, Christoph Faul, Karsten Spiekermann, Knut Wendelin, Maher Hanoun, Ralph Wäsch, Joachim Beck, Sonja Martin, Vladan Vucinic, Claudia D. Baldus, Monika Brüggemann, Thomas Burmeister, Heike Pfeifer, Stefan Schwartz, Lena Baumann, Diana Tichy, Hubert Serve, Walter Fiedler
Journal: Blood
Blood (2021) 138 (Supplement 1): 362.
https://doi.org/10.1182/blood-2021-146306
Published: 2021